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These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "117": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "111": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "276": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "2147": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "794": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "2146": {"$update": {"model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "2145": {"$update": {"model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "3": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "2078": {"$update": {"model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "919": {"$update": {"model_sequences": {"$update": {"sequence": {"$insert": {"3414": {"dna_sequence": {"fmax": "1211", "fmin": "284", "accession": "Z21957.1", "strand": "-", "sequence": "TTAATTTGGGCTTAGGGCAGAAAGCTTTTTCAATTCAAATTGATACGCAGTCTGAGCAACCTGCGCAATGATAGCTTCATTGGTTCGGCTTGACTCGGCTGAGTCTTTCACAAAAACAGCAACCAGCAAGGGCCGTCCATCAGGCAACAGAATGATACCTAAATCATTAGTGGCCGCAGTTTTTCCGGCTTTGATACCCGAAGTACCAGTTTTATGTGCGACCACAGTACCAGCTGGTAACAAACCTTTTAACCGCTCTGGTCCTGTGGTGGTTTCGACCATCCACTTCCATAACAAAGCCTGCGAGGTTTCAGACAGCTGTGTTTTTTGCTCAAACTTTTTCAGGATCTCTGCAGCACCTTTCATCGAGGTCCAGTTTTGATACTGCACCTGATCATCGGCGTGCATCTGCGCTTCATTTGCGACCACAGCGGTCTCCTTTATACCCATAGACTGGATATAGTCATGCAAAGCAGCTGGTCCACCAACCAGTTCAAATAACAAATCACAGGCCACGTTATCGCTGTGCGAGACCGAGTATTGCAGCAGTTGCTGCACTGGAACACTAAACTCGTCTCCCTGATACGCTTTCATTATCGGAGCCCAGGTATTCTGTAAAACCTTAGCCCTGTTTACGATAACGGTCTGATTTAAATCCAACTTTCCCTGATCAACCTGATGCAGTACCAACATAGCTAAATGCAATTTAAATACACTTTGCATTGGGAATTTTTCAAAAGGATTAATCAGTAAAGGTTCCAGATCGTCAGGCCCCCACACTGCAACGCCTACAGTGGCTTTTTTTCCAATGACTATGGATTCAATTTGCTCTTTTAACAGTGGGGATTGCGCTGAGGTTTCGAATGAACTAAAAGATACCATCAGTAGCGTCGAGGCAGTAACTACAGCTTTTATAATGACATTCAT"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Pseudomonas aeruginosa", "NCBI_taxonomy_id": "287", "NCBI_taxonomy_cvterm_id": "36752"}, "protein_sequence": {"GI": "CAA79968.1", "sequence": "MNVIIKAVVTASTLLMVSFSSFETSAQSPLLKEQIESIVIGKKATVGVAVWGPDDLEPLLINPFEKFPMQSVFKLHLAMLVLHQVDQGKLDLNQTVIVNRAKVLQNTWAPIMKAYQGDEFSVPVQQLLQYSVSHSDNVACDLLFELVGGPAALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQALLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGIKAGKTAATNDLGIILLPDGRPLLVAVFVKDSAESSRTNEAIIAQVAQTAYQFELKKLSALSPN"}}}}}}}}, "2073": {"$update": {"model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "914": {"$update": {"model_sequences": {"$update": {"sequence": {"3403": {"dna_sequence": {"fmax": "61860", "fmin": "60996", "accession": "NC_023287", "strand": "-", "sequence": "TTAAAAATAGTCATTTTCAACATATTTTTTATACATGTCCTCGGTATATCTTGTTATGTTCTTACCATACTCTGGATAATCAAACCCCAGTAGTTCTGCTACCTCTTTGGACACTTCCCTGAACAATTGGTGGCATATAAATAATGACTTCCAAATATTTTCATAGGAATCCATGCGATATGTAGATAATAATCTATTCCATAGATCTTCATCAATGTATTTGTTAATATACTTATAATTTTTCCCAACACTTAATGAAAATTCTGTCTTTATCCCAACCTTCCACGACATCATCCTAAGTAGTTCAAACCGTAGAATCTGGTTCAGATGATCGATTGCAAACAGTATCTCTTTGCGGCACAATCCTTTAATAACATAAGGTGTTACATTCCAAAATTCATTGCAGCAATCATCATACTCCCTTGCGCTTGGCTTTCTTACATGATAATCTATATCAGTCGGAACTATGTCCCTTTTAATTCTACAATCTTTATCAATTAGAACCTTTATTAATTTATCGCCCTTTAGGTAATTATCTAACTCTTCCAAGGGCAATAAGGTAAGATCAATTTTATTGTAATCATCAAATAGCATAAGATAGGAAAATCCCTTTTCTTCAGGTGGGAATAATTCCATATCCTCCGGCTTTTGCATCATTATTATATTCCCAAATTGATTAAGCCAGTCATCATTAGATATAAACGGTTCTATATCACTTACAAAATATGTAATATCATAATCCTGAAATTCATCTTTAGGTATATTAATATTTGCGCGTGACCCCTCAAGGGTCACAATTCGAATACGTTCATCCTGTTCTGCTAAAGAAAGTACTAAATCCATCATTTCTTTTTCTGATCTCAT"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Exiguobacterium sp. S3-2", "NCBI_taxonomy_id": "1389960", "NCBI_taxonomy_cvterm_id": "39580"}, "protein_sequence": {"GI": "571046704", "sequence": "MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYDITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLTLLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNVTPYVIKGLCRKEILFAIDHLNQILRFELLRMMSWKVGIKTEFSLSVGKNYKYINKYIDEDLWNRLLSTYRMDSYENIWKSLFICHQLFREVSKEVAELLGFDYPEYGKNITRYTEDMYKKYVENDYF"}}}}}}}, "1395": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "2070": {"$update": {"model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "2077": {"$update": {"model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "2076": {"$update": {"model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "1405": {"$update": {"model_sequences": {"$update": {"sequence": {"$insert": {"3397": {"dna_sequence": {"fmax": "774", "fmin": "0", "accession": "GU437214.1", "strand": "+", "sequence": "ATGGATAAGAATGATGTTGTTAAGAAGATACTTGAATCAAAAAAGTACGAAAACCTTGATTCAGATATTGTTGAAAAGGTTGTTTCCATTTCTGAGAAGAAATATAAATTAAAGGAAGTTGAGAATTATTCTAAAAAGAAATTGCATCAAATATGGGGGTCTTACTATTCTGCCTATCCTAATTGGGATAAATTATTAAAAAAGTACAATCAGGGGCAGTTATCAATAGAAGATTTACTAAAGATTCATTCTTCGACGAATGAAAGAGTCGCAACATTAAATGACTTTTACACTTATGTATTTGGAAATATCAAACATGTCTCATCTATTTTAGATTTTGGTTGTGGCTTCAATCCATTAGCTTTATACCAATGGAATGAAAATGAAAAAATAATATATCATGCATACGATATTGATAGAGCTGAGATAGCTTTTTTGAGTAGCATTATTGGGAAGTTAAAGACGACGATAAAGTATAGGTTTTTGAATAAAGAGAGTGATGTCTACAAAGGTACTTATGATGTAGTATTCCTTTTAAAGATGCTTCCTGTGCTAAAACAGCAAGATGTAAATATCTTGGATTTCCTACAGCTTTTTCATACTCAAAACTTTGTAATATCTTTTCCAATAAAGTCTTTATCTGGAAAGGAGAAGGGAATGGAAGAGAATTACCAGCTATGGTTTGAATCTTTTACAAAAGGTTGGATAAAAATCCTTGATTCGAAGGTTATAGGGAATGAGTTAGTATATATTACTAGTGGATTTCAGAAATAA"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Pseudomonas aeruginosa", "NCBI_taxonomy_id": "287", "NCBI_taxonomy_cvterm_id": "36752"}, "protein_sequence": {"GI": "ADC55560.1", "sequence": "MDKNDVVKKILESKKYENLDSDIVEKVVSISEKKYKLKEVENYSKKKLHQIWGSYYSAYPNWDKLLKKYNQGQLSIEDLLKIHSSTNERVATLNDFYTYVFGNIKHVSSILDFGCGFNPLALYQWNENEKIIYHAYDIDRAEIAFLSSIIGKLKTTIKYRFLNKESDVYKGTYDVVFLLKMLPVLKQQDVNILDFLQLFHTQNFVISFPIKSLSGKEKGMEENYQLWFESFTKGWIKILDSKVIGNELVYITSGFQK"}}}}}}}}, "2074": {"$update": {"model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "1235": {"$update": {"model_sequences": {"$update": {"sequence": {"3393": {"dna_sequence": {"fmax": "3902", "fmin": "0", "accession": "AY660529.1", "strand": "+", "sequence": "GGCATCCAAGCAGCAAGCGCGTTACGCCGTGGGTCGATGTTTGATGTTATGGAGCAGCAACGATGTTACGCAGCAGGGCAGTCGCCCTAAAACAAAGTTAGGCATCACAAAGTACAGCATCGTGACCAACAGCAACGATTCCGTCACACTGCGCCTCATGACTGAGCATGACCTTGCGATGCTCTATGAGTGGCTAAATCGATCTCATATCGTCGAGTGGTGGGGCGGAGAAGAAGCACGCCCGACACTTGCTGACGTACAGGAACAGTACTTGCCAAGCGTTTTAGCGCAAGAGTCCGTCACTCCATACATTGCAATGCTGAATGGAGAGCCGATTGGGTATGCCCAGTCGTACGTTGCTCTTGGAAGCGGGGACGGATGGTGGGAAGAAGAAACCGATCCAGGAGTACGCGGAATAGACCAGTCACTGGCGAATGCATCACAACTGGGCAAAGGCTTGGGAACCAAGCTGGTTCGAGCTCTGGTTGAGTTGCTGTTCAATGATCCCGAGGTCACCAAGATCCAAACGGACCCGTCGCCGAGCAACTTGCGAGCGATCCGATGCTACGAGAAAGCGGGGTTTGAGAGGCAAGGTACCGTAACCACCCCAGATGGTCCAGCCGTGTACATGGTTCAAACACGCCAGGCATTCGAGCGAACACGCAGTGTTGCCTAACCCTTCCATCGAGGGGGACGTCCAAGGGCTGGCGCCCTTGGCCGCCCCTCATGTCAAACGTTAGCCACCAAGAAGGTGCCATGAAAACATTTGCCGCATATGTAATTACTGCGTGTCTTTCAAGTACGGCATTAGCTAGTTCAATTACAGAAAATACGTTTTGGAACAAAGAGTTCTCTGCCGAAGCCGTCAATGGTGTTTTCGTGCTTTGTAAAAGTAGCAGTAAATCCTGCGCTACCAATAACTTAGCTCGTGCATCAAAGGAATATCTTCCAGCATCAACATTTAAGATCCCCAACGCAATTATCGGCCTAGAAACTGGTGTCATAAAGAATGAGCATCAGATTTTCAAATGGGACGGAAAGCCAAGAGCCATGAAACAATGGGAAAGAGACTTGAGCTTAAGAGGGGCAATACAAGTTTCAGCGGTTCCCGTATTTCAACAAATCGCCAGAGAAGTTGGCGAAGTAAGAATGCAGAAATATCTTAAAAAATTTTCATATGGTAACCAGAATATCAGTGGTGGCATTGACAAATTCTGGTTGGAGGGTCAGCTTAGAATTTCCGCAGTTAATCAAGTGGAGTTTCTAGAGTCTCTATTTTTAAATAAATTGTCAGCATCAAAAGAAAATCAGCTAATAGTAAAAGAGGCTTTGGTAACGGAGGCTGCGCCTGAATATCTTGTGCATTCAAAAACTGGTTTTTCTGGTGTGGGAACTGAGTCAAATCCTGGTGTCGCATGGTGGGTTGGTTGGGTTGAGAAGGGAGCAGAGGTTTACTTTTTCGCCTTTAACATGGATATAGACAACGAAAATAAGTTGCCGCTAAGAAAATCCATTCCCACCAAAATCATGGCAAGTGAGGGCATCATTGGTGGCTAACAATTCGCTGCAGGCGCGACGGCCCTGACGGGTCCGCGGCCTGAGCTCAAACGTTAGACATCATGAGTGAAAAAGTGCCCGCCGAGATTTCGGTGCAACTATCACAAGCACTCAACGTCATCGGGCGCCACTTGGAGTCGACGTTGCTGGCCGTGCATTTGTACGGCTCCGCACTGGATGGCGGATTGAAACCGTACAGTGATATTGATTTGCTGGTGGCTGTAGCTGCACCGCTCAATGATGCCGTGCGGCAAGCCCTGCTCGTCGATCTCTTGGAGGTTTCAGCTTCCCCTGGCCAAAACAAGGCACTCCGCGCCTTGGAAGTGACCATCGTCGTGCACAGTGACATCGTACCTTGGCGTTATCCGGCCAGGCGGGAACTGCAGTTCGGAGAGTGGCAGCGCAAAGACATCCTTGCGGGCATCTTCGAGCCCGCCACAACCGATTCTGACTTGGCGATTCTGCTAACAAAGGCAAAGCAACATAGCATCGTCTTGGCAGGTTCAGCAGCGAAGGATCTCTTCAGCTCAGTCCCAGAAAGCGATCTATTCAAGGCACTGGCCGATACTCTGAAGCTATGGAACTCGCCGCCAGATTGGGCGGGCGATGAGCGGAATGTAGTGCTTACTTTGTCTCGTATCTGGTACACCGCAGCAACCGGCAAGATCGCGCCAAAGGATGTTGCTGCCACTTGGGCAATGGCACGCTTGCCAGCTCAACATCAGCCCATCCTGTTGAATGCCAAGCGGGCTTATCTTGGGCAAGAAGAAGATTATTTGCCCGCTCGTGCGGATCAGGTGGCGGCGCTCATTAAATTCGTGAAGTATGAAGCAGTTAAACTGCTTGGTGCCAGCCAATGATGTCTAACAATTCATATATGGACTCTCCCCACAAGCAGTGAGGAAAGCTTTTTTCGATCCTGTCGTCAGCGCGGTTGCATTCGTATATCCGGCCTTGTCGTGGGCAGTGCCCTGGCCATGCTGTAGTTCGCGCAGCGGGGGCCAAGCGTTCAAACGATCCCGAAGATCATGATTGTTATCGGCCTTGTACCGCTGCAGGACTCGCCTGTTCCGACAGTCTCGCTTCTCACCACAACCGCAAGAAATAACGCGTCTTCCTGATTACCCCGCCGTCAGGCGGGCCTTGCACTCTGCCAGTCGCCACTGAAGCGGCGTTCGTGGCACCACACCGCCCAGCAGATCCTCACCAGTTTGTTCGCCAGGGCCACGGCAGCCTTGTTGTGGCCGATGCGTTCGGCCGTCTGCAGGGCCCAGCGCTGCAGCTGGGTCAGGCGTTGCGGCGTTCGTGCCTGGCAGCGCTTGGCGGCCAGCAACGCCGCGCGGGCGCCGTGGATCAGCAGCGTTCGCACGTAAACATTGCCCTTGCAGCTGATGCGGCCGAGCTTGCGGCGCTCGCCGCTGCTGTATTCGTTGGGCGTCATGCCCAGCCAGGCGCTCAGATGCCGGCCGCTGGCAAAGCGTTCGGGTTTGCCCACAGCGGTTTTCAGGGCGCTGGCGGTGAGCAGGCCGATGCCGCTGACTTCATCGAGCTTGTGCACGATGTCGTCGTCGGCATGCCAGCGCGCCAGTTGGTCTTCGCACTCACGCATCGACTGTTCGTAGAGGTTGATTTCAGCCAGTACCACTTGCAGGACACCACGCAGAGCCTGCACCTCGGGCTGCTCGATCAACGCGCAGGCCTGGCGCAGAAACGCCTGGGTGCCGTTGGGCGCGGCCACGCCCATCTCGCGCAGGATGCCGCGCAACAGGTTGATGCGCTGGACCCGGGTCTTCTTCCAGGCCTCGCGCATTTTGTGCAGCTGCTGCACCTGTTGCTGCTGCACGCTTTTGACCGGCACCGGACGGATACCCTCGCAACGAGCCGCCTCCAGGATCGCATCGCAGTCGTTGCGATCGGTCTTACTGCGCCGGCGATAGGCCCGCACGTAGCGCGGATGCAGCAGCACCACGCGATGCCCCGCCGCCTGCATCAACCGGCCCCAGTGGTGAGCCGTGCCGCAGGCCTCCATCACCCACTCGACAGGCGCCGGCTGCTCCTGTACATAACGCCAGAACGCCTCCGGATCGAGCCGCCTGCGACGATCCACCCGACCGACATGGATACTTTCGGCAACTTGGTAAACGGACTTGGCCAAATCAATTGCAATGCGTTTCATCTTCACTCTCCCGGCAAACAGACACCTCGTGTCTTATAGAAGAAACGCGGTGCGGGGAGAGTCCATTACAGCCTTCAAGCCGACGCCGCTTCGCGGCGCGGCTTAATTCAAGCGTTAGATGCACTAAGCACATAATTGCTCACAGCCAAACTATCAGGTCAAGTCTGCT"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Pseudomonas aeruginosa", "NCBI_taxonomy_id": "287", "NCBI_taxonomy_cvterm_id": "36752"}, "protein_sequence": {"GI": "AAT74613.1", "sequence": "MTNSNDSVTLRLMTEHDLAMLYEWLNRSHIVEWWGGEEARPTLADVQEQYLPSVLAQESVTPYIAMLNGEPIGYAQSYVALGSGDGWWEEETDPGVRGIDQSLANASQLGKGLGTKLVRALVELLFNDPEVTKIQTDPSPSNLRAIRCYEKAGFERQGTVTTPDGPAVYMVQTRQAFERTRSVA"}}}}}}}, "1237": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "1339": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "1135": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "1935": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "100": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "1849": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "1432": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). 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In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "2104": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "1166": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "1203": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "1894": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "2136": {"$update": {"model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "2137": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "2132": {"$update": {"model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "1055": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "2131": {"$update": {"model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "1966": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "1192": {"$update": {"ARO_description": "VEB-1 is a beta-lactamase found in Escherichia coli and Pseudomonas aeruginosa.", "model_sequences": {"$update": {"sequence": {"$insert": {"3418": {"dna_sequence": {"fmax": "627", "fmin": "0", "accession": "KT283240.1", "strand": "+", "sequence": "ATGCAAAGCGTTATGAAATTTCCGATTGCTTTAGCCGTTTTGTCTGAGATAGATAAAGGGAATCTTTCTTTTGAACAAAAAATAGAGATTACCCCCCAAGACCTTTTGCCTAAAACGTGGAGTCCGATTAAAGAGGAATTCCCTAATGGAACAACTTTGACGATTGAACAAATACTAAATTATACAGTATCAGAGAGCGACAATATTGGTTGTGATATTTTGCTAAAATTAATCGGAGGAACTGATTCTGTTCAAAAATTCTTGAATGCTAATCATTTCACTGATATTTCAATCAAAGCAAACGAAGAACAAATGCACAAGGATTGGAATACCCAATATCAAAATTGGGCAACCCCAACAGCGATGAACAAACTGTTAATAAATACTTATAATAATAAGAACCAATTACTTTCTAAAAAAAGTTATGATTTTTTTTGGAAAATTATGAGAGAAACAACAACAGGAAGTAACCGATTAAAAGGACAATTACCAAAGAATACAATTGTTGCTCATAAAACAGGGACTTCCGGAATAAATAATGGAATTGCAGCAGCCACTAATGATGTTGGGGTAATTACTTTACCGAATGGACAATTAATTTTTATAAGCGTATTTGTTGCAGAGTCC"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Pseudomonas aeruginosa", "NCBI_taxonomy_id": "287", "NCBI_taxonomy_cvterm_id": "36752"}, "protein_sequence": {"GI": "ALC76810.1", "sequence": "MQSVMKFPIALAVLSEIDKGNLSFEQKIEITPQDLLPKTWSPIKEEFPNGTTLTIEQILNYTVSESDNIGCDILLKLIGGTDSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLINTYNNKNQLLSKKSYDFFWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGINNGIAAATNDVGVITLPNGQLIFISVFVAES"}}}}}}}}, "2066": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants."}}, "1197": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "1696": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "1441": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "1176": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "1175": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "1474": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "1710": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "489": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "1354": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "2133": {"$update": {"model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "2088": {"$update": {"model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "2122": {"$update": {"model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "2124": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "2127": {"$update": {"model_sequences": {"$update": {"sequence": {"$update": {"3266": {"$update": {"dna_sequence": {"$update": {"fmin": "0"}}, "NCBI_taxonomy": {"$update": {"NCBI_taxonomy_cvterm_id": "40345"}, "$insert": {"NCBI_taxonomy_name": "Borrelia burgdorferi", "NCBI_taxonomy_id": "139"}}}}}}}}, "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "2126": {"$update": {"model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "2129": {"$update": {"model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "2128": {"$update": {"model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "2080": {"$update": {"model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "2086": {"$update": {"model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "2084": {"$update": {"model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "2085": {"$update": {"model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "1360": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "516": {"$update": {"model_param": {"$update": {"blastp_evalue": {"$update": {"param_value": "1e-150"}}}}}}, "953": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}, "1574": {"$update": {"model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "model_param": {"$update": {"snp": {"$update": {"param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}}}}}}, "$delete": ["2199"], "$insert": {"2204": {"model_id": "2204", "ARO_accession": "3002548", "ARO_description": "AAC(6')-IId is an integron-encoded aminoglycoside acetyltransferase in P. aeruginosa, E. cloacae, and C. freundii.", "model_sequences": {"sequence": {"3392": {"dna_sequence": {"fmax": "405451", "fmin": "404932", "accession": "KC543497.1", "strand": "+", "sequence": "ATGACTGAGCATGACCTTGCGATGCTCTATGAGTGGCTAAATCGATCTCATATCGTCGAGTGGTGGGGCGGAGAAGAAGCACGCCCGACACTTGCTGACGTACAGGAACAGTACTTGCCAAGCGTTTTAGCGCAAGAGTCCGTCACTCCATACATTGCAATGCTGAATGGAGAGCCGATTGGGTATGCCCAGTCGTACGTTGCTCTTGGAAGCGGGGACGGATGGTGGGAAGAAGAAACCGATCCAGGAGTACGCGGAATAGACCAGTCACTGGCGAATGCATCACAACTGGGCAAAGGCTTGGGAACCAAGCTGGTTCGAGCTCTGGTTGAGTTGCTGTTCAATGATCCCGAGGTCACCAAGATCCAAACGGACCCGTCGCCGAGCAACTTGCGAGCGATCCGATGCTACGAGAAAGCGGGGTTTGAGAGGCAAGGTACCGTAACCACCCCAGATGGTCCAGCCGTGTACATGGTTCAAACACGCCAGGCATTCGAGCGAACACGCAGTGATGCCTAA"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Pseudomonas aeruginosa PA96", "NCBI_taxonomy_id": "1457392", "NCBI_taxonomy_cvterm_id": "40337"}, "protein_sequence": {"GI": "AGL46466.1", "sequence": "MTEHDLAMLYEWLNRSHIVEWWGGEEARPTLADVQEQYLPSVLAQESVTPYIAMLNGEPIGYAQSYVALGSGDGWWEEETDPGVRGIDQSLANASQLGKGLGTKLVRALVELLFNDPEVTKIQTDPSPSNLRAIRCYEKAGFERQGTVTTPDGPAVYMVQTRQAFERTRSDA"}}}}, "ARO_category": {"36696": {"category_aro_name": "antibiotic inactivation enzyme", "category_aro_cvterm_id": "36696", "category_aro_accession": "3000557", "category_aro_description": "Enzyme that catalyzes the inactivation of an antibiotic resulting in resistance.  Inactivation includes chemical modification, destruction, etc."}, "36243": {"category_aro_name": "aminoglycoside resistance gene", "category_aro_cvterm_id": "36243", "category_aro_accession": "3000104", "category_aro_description": "Genes conferring resistance to aminoglycoside antibiotics."}}, "ARO_name": "AAC(6')-IId", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "38948", "model_name": "AAC(6')-IId", "model_type_id": "40292"}, "2205": {"model_id": "2205", "ARO_accession": "3003692", "ARO_description": "mexJ is the membrane fusion protein of the MexJK multidrug efflux protein.", "model_sequences": {"sequence": {"3399": {"dna_sequence": {"fmax": "4120373", "fmin": "4119269", "accession": "NC_002516.2", "strand": "-", "sequence": "CTACTCCTTGGCCGCCAGTTTCACCGTGCGGTTGGCCCGGTCGATCGGACGCACCTGCTGCCCTTCGCGAAGCACCTGGACCCCGGTGGCCACCACCCAGTCGCCAGCCTTCAGGCCTTCGAGCACCGGCACCCGGTCCTCGGCATAGGGACCGGTGCGCACCGCCTGCCGGCGCAGGGTCGAGCTGCCCGGCTCGACCACCCAGACGAACGCCTGGCCGGCCTCTGCGGTCAGCGCCGACAAGGGAACCGATAACGGCACCGCCTCGGCGGCGGCGACGTAGACCCGCGCGCTCTGGCCCAGTTCGGCCGGAGTCGCGCGGTCGTCGAAGGCCACCCGGGCGGCGAAGGTACGCGATTGCGGATCGGCCGCGGGCGAGAGCTCGCGGATATGCCCGGCGAAGCGTCTGTCGCGTTGCGACCAGAGTTCGACCGACACCGGCTGGCCGATGCGGAAACGTTCGAAGCTGTGTTCCGGCAGGCCGATCAGCACCTCGCGTTCGCCGTCGGCGGCCAGGCTGAAGACCGTCTGTCCGGCCGCCACCACCTGGCCCACCTCGACGCGCCGGCTGGCGATCACGCCATCCTGGGGCGAGCGCAGCACGGCGTAGCCGGCCTGGTTGTCGGCGACGTTGAATTCGGCGCGGATCTGCTTCAGCCGCGCCTCGCCGGCGCGGTAGCTGTTCTGGATGTTCTCGAACTGGGAATGGCTGACCAGGTTGCGGTCGAGCAAGGTGCGGTAGCGCCGGTACTCGGCGCGCACGGTCTGCAAGTTGGCCTCGGCGGCACTGACCTGGGCCCGCGCCGCCTCCAGTTGCAGGCGCACGTCCTGGGGATCGAGTTCGGCCAGGGGCTGGTCCTTCTTTACCCGCTCGCCGACTTCCACCAGCCGGCGGATGACCTTGCCGCCGATGCGGAAGGCCAGCTCCGGCTCGTGGCGGGCGCGGATCTCGCCGGGAAAGGCCTGGCTCACCTCCCCCGCCGGCTGGGGCTGGACGACGATCGCCGGACGCGCCGCGGCTGGCGGCGGCGTGCCGTTGCCGCAGGCGGCGAGGAACAGGGAGGAAAACAGGGACAGGGCGACGAGCGGGATATGGCGGTACAT"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Pseudomonas aeruginosa PAO1", "NCBI_taxonomy_id": "208964", "NCBI_taxonomy_cvterm_id": "36804"}, "protein_sequence": {"GI": "NP_252367.1", "sequence": "MYRHIPLVALSLFSSLFLAACGNGTPPPAAARPAIVVQPQPAGEVSQAFPGEIRARHEPELAFRIGGKVIRRLVEVGERVKKDQPLAELDPQDVRLQLEAARAQVSAAEANLQTVRAEYRRYRTLLDRNLVSHSQFENIQNSYRAGEARLKQIRAEFNVADNQAGYAVLRSPQDGVIASRRVEVGQVVAAGQTVFSLAADGEREVLIGLPEHSFERFRIGQPVSVELWSQRDRRFAGHIRELSPAADPQSRTFAARVAFDDRATPAELGQSARVYVAAAEAVPLSVPLSALTAEAGQAFVWVVEPGSSTLRRQAVRTGPYAEDRVPVLEGLKAGDWVVATGVQVLREGQQVRPIDRANRTVKLAAKE"}}}}, "ARO_category": {"36298": {"category_aro_name": "efflux pump conferring antibiotic resistance", "category_aro_cvterm_id": "36298", "category_aro_accession": "3000159", "category_aro_description": "Efflux proteins that pump antibiotic out of a cell to confer resistance."}, "36611": {"category_aro_name": "tetracycline resistance gene", "category_aro_cvterm_id": "36611", "category_aro_accession": "3000472", "category_aro_description": "Genes conferring resistance to tetracycline antibiotics."}}, "ARO_name": "mexJ", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "40340", "model_name": "mexJ", "model_type_id": "40292"}, "2206": {"model_id": "2206", "ARO_accession": "3003693", "ARO_description": "mexK is the inner membrane resistance-nodulation-cell division (RND) transporter in the MexJK multidrug efflux protein.", "model_sequences": {"sequence": {"3400": {"dna_sequence": {"fmax": "4119265", "fmin": "4116187", "accession": "NP_252366.1", "strand": "-", "sequence": ""}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Pseudomonas aeruginosa PAO1", "NCBI_taxonomy_id": "208964", "NCBI_taxonomy_cvterm_id": "36804"}, "protein_sequence": {"GI": "AAG07064.1", "sequence": "MSFNLSAWALQNRQIVLYLMILLGAVGALSYSKLGQSEDPPFTFKAMVVQTNWPGASAEEVARQVTERIEKKLMETGDYDRIVSFSRPGVSQVTFMAREDIHSSEIPELWYQIRKKISDIRATLPQSIQGPFFNDEFGTTYGNIYALTGKGFDYAVMKDYADRLQLQLQRIRNVGKVELIGLQDEKIWIDLSNTKLATLGLPLAAVQKALEEQNAVASSGFFETASDRVQLRVSGRFDSVEEIRDFPIRVGDRTFRIGDVAEVRRGFNDPPAPRMRFMGEDAIGLAVAMKPGGDILVLGKALETEFARLQQSLPAGLELRKVSDQPAAVRTGVGEFIRVLAEALVIVLLVSFFSLGLRTGLVVALSIPLVLAMTFAAMHYFGIGLHKISLGALVLALGLLVDDAIIAVEMMAVKMEQGYDRLKAASFAWTSTAFPMLTGTLITAAGFLPIATAQSGTGEYTRSLFQVVTIALVVSWFAAVVFVPYLGAKLLPDLARLHAQKHGGSADGYDPYATAFYQRFRRLVEWCVRYRKTVIVLTLAAFVGALLLFRLVPQQFFPPSARLELLLDIKLAEGASLRSTGEEVQRLEKMLQGHDGIDNYVAYVGTGSPRFYLPLDQQLPAASFAQVVVLAKDLESREALRKWLIERMNEDFPHLRSRISRLENGPPVGYPVQFRVSGEDIPQVRELARKVADKMRENPHVVNVHLDWEEPSKVVYLSIDQERARALGVSTASLSQFLQSALTGSHVSFFREDNELIEILLRGTEQERRDLSLLPSLAVPTENGRSVALSQIATLEYGFEEGIIWHRNRLPTVTVRADIYDDSLPATLVAQIAPTLEPIRAELPDGYLLEVGGTVEDAAKGQSSVNAGVPLFIVVVLSLLMVQLRSFSRMAMVFLTAPLGLIGVTLFLLLFRQPFGFVAMLGTIALAGMIMRNSVILVDQIEQDISHGLDRWHAIIEATVRRFRPIVLTALAAVLAMIPLSRSVFFGPMAVAIMGGLIVATVLTLLFLPALYAAWFRVKKDEARA"}}}}, "ARO_category": {"36298": {"category_aro_name": "efflux pump conferring antibiotic resistance", "category_aro_cvterm_id": "36298", "category_aro_accession": "3000159", "category_aro_description": "Efflux proteins that pump antibiotic out of a cell to confer resistance."}, "36611": {"category_aro_name": "tetracycline resistance gene", "category_aro_cvterm_id": "36611", "category_aro_accession": "3000472", "category_aro_description": "Genes conferring resistance to tetracycline antibiotics."}}, "ARO_name": "mexK", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "40341", "model_name": "mexK", "model_type_id": "40292"}, "2207": {"model_id": "2207", "ARO_accession": "3003030", "ARO_description": "MexV is the membrane fusion protein of the MexVW-OprM multidrug efflux complex.", "model_sequences": {"sequence": {"3401": {"dna_sequence": {"fmax": "4904596", "fmin": "4903465", "accession": "NP_253064.1", "strand": "+", "sequence": ""}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Pseudomonas aeruginosa PAO1", "NCBI_taxonomy_id": "208964", "NCBI_taxonomy_cvterm_id": "36804"}, "protein_sequence": {"GI": "AAG07762.1", "sequence": "MLLRRMLIMLAAVIAVVAILAGYKVYSIRQQIALFSAPKPPISVTASLAEKRPWQSRLPAIGSLKAFQGVTLTAEVSGTVRDVLFLSGDQVKLDQPLIQLESDVEEATLRTAEADLGLARAEYQRGRELIGSKAISKSEFDRLAAQWAKTSATVAELKAALAKKRVLAPFAGTIGIRQVDVGDYVSPGTPIATLQDLSTLLLDFHLPEQDFPLLSRGQLVKVRVAAYPAQVFDAEIAAINPKVDNETRNLQVRAALENPDGKLLPGMFANLEVMLPGEEQRVVVPETAITFTLYGDSIYVVGQKKDEQGQVSKDDKGQPQQVVERRFVRIGERREGLAVVLEGLEGGEQVVTSGQLKLDNGAAVAIVAERDLQQEH"}}}}, "ARO_category": {"36298": {"category_aro_name": "efflux pump conferring antibiotic resistance", "category_aro_cvterm_id": "36298", "category_aro_accession": "3000159", "category_aro_description": "Efflux proteins that pump antibiotic out of a cell to confer resistance."}, "36537": {"category_aro_name": "chloramphenicol resistance gene", "category_aro_cvterm_id": "36537", "category_aro_accession": "3000398", "category_aro_description": "Genes conferring resistance to chloramphenicol."}, "36611": {"category_aro_name": "tetracycline resistance gene", "category_aro_cvterm_id": "36611", "category_aro_accession": "3000472", "category_aro_description": "Genes conferring resistance to tetracycline antibiotics."}, "36241": {"category_aro_name": "fluoroquinolone resistance gene", "category_aro_cvterm_id": "36241", "category_aro_accession": "3000102", "category_aro_description": "Genes conferring resistance to fluoroquinolones."}}, "ARO_name": "mexV", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "39464", "model_name": "mexV", "model_type_id": "40292"}, "2208": {"model_id": "2208", "ARO_accession": "3003031", "ARO_description": "MexW is the RND-type membrane protein of the efflux complex MexVW-OprM.", "model_sequences": {"sequence": {"3402": {"dna_sequence": {"fmax": "4907703", "fmin": "4904646", "accession": "\tNP_253065.1", "strand": "+", "sequence": ""}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Pseudomonas aeruginosa PAO1", "NCBI_taxonomy_id": "208964", "NCBI_taxonomy_cvterm_id": "36804"}, "protein_sequence": {"GI": "AAG07763.1", "sequence": "MAFTDPFIRRPVLASVVSLLIVLLGMQAFSKLVIREYPQMENALITVTTLYAGANAETIQGYITQPLQQSLASAEGIDYMTSVSRQNYSTISIYARIGANTDRLVTELLAKSNEVKSQLPPDAEDPVLQKEAADASALMYISFYSEQMNNPQITDYLSRVIQPKLATLPGIAEAEILGNQVFAMRLWLDPVKMAAFGVTAGEINQAVQQYNFLAAAGEVKGQLVVTSVNASTDLKSPQAFAAIPVKTDGDRRVLMGDVARVELGAASYDAISSFNGIPSVYIGIKGTPSANPLDVIKEVRAKMPELEEQLPPNLKVSIAYDATRFIQASIDEVVKTLGEAVLIVIVVVFLFLGAFRSVLIPVVTIPLSMIGVLFFMQAMGYSINLLTLLAMVLAIGLVVDDAIVVVENIHRHIEEGKPPFEAALEGAREIAVPVVSMTITLAAVYAPIGFLTGLTGALFKEFAFTLAGAVIISGIVALTLSPMMCSRLLRHEENPSGLAHRLDLIFEGLKQRYQRALHGTLDTRPVVLVFAVLVLALIPVLLMFTKKELAPEEDQGIVFLMTNSPQTANLDYLNRYTAEFEGIFRSFPEYYSAFQINGYNGVQAGIGGMLLKPWDEREKSQMELLHAVQAKLNEIPGVQIFAFNLPSLPGTGEGLPFQFVLNTANDYESLLQVAQRVKQRASESGKFAFLDLDLAFDKPELVVDIDREKAAQMGVSMQDLGVALASLLGEGEINRFTIDGRSYKVIAQVERPYRDNPGWLGSYYVKSRNGQLVALSTLIETHERARPRQLNQFQQLNSAIISGFPIVSMGEAIETVQQIAREEAPRGFAVDYAGASRQYVQEGSALLVTFGLALAIIFLVLAAQFESFRDPLVIMVTVPLSICGALIPLFLGVSSLNIYTQVGLVTLIGLISKHGILIVEFANQLRHEQGLGRREAIEQAAAIRLRPVLMTTAAMVLGVIPLILATGAGAVSRFDIGIVIATGMSVGTLFTLFVLPCIYTLVARPDAPPGVTQAANAH"}}}}, "ARO_category": {"36298": {"category_aro_name": "efflux pump conferring antibiotic resistance", "category_aro_cvterm_id": "36298", "category_aro_accession": "3000159", "category_aro_description": "Efflux proteins that pump antibiotic out of a cell to confer resistance."}, "36537": {"category_aro_name": "chloramphenicol resistance gene", "category_aro_cvterm_id": "36537", "category_aro_accession": "3000398", "category_aro_description": "Genes conferring resistance to chloramphenicol."}, "36611": {"category_aro_name": "tetracycline resistance gene", "category_aro_cvterm_id": "36611", "category_aro_accession": "3000472", "category_aro_description": "Genes conferring resistance to tetracycline antibiotics."}, "36241": {"category_aro_name": "fluoroquinolone resistance gene", "category_aro_cvterm_id": "36241", "category_aro_accession": "3000102", "category_aro_description": "Genes conferring resistance to fluoroquinolones."}}, "ARO_name": "mexW", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "39465", "model_name": "mexW", "model_type_id": "40292"}, "2227": {"model_id": "2227", "ARO_accession": "3003713", "ARO_description": "VCC-1 is a Class A carbapenemase isolated from Vibrio cholerae and exhibits resistance to penicillins, carbapenems and monobactam antibiotics.", "model_sequences": {"sequence": {"3430": {"dna_sequence": {"fmax": "10865", "fmin": "10010", "accession": "KT818596", "strand": "+", "sequence": "ATGAAACGTATTGCTATGTATGTTGCATTATCAATCTCTACTTCAACAGCTTTCGCTGATGAGCACAACAAAAATATGGCTGATATTGAAGCTGCTTTTGAGGGGCGTGTCGGTGTTTACGCAATAAACACTGGCAGCGGCAAGGCATATTCATATCGAGCTAACGAACGCTTCCCCTTATGTAGTTCATTTAAAGCATTTTTGGCGGCAGCAGTTTTAAAAATGGATCAAGATAGTCCTGGAGTCCTGCTTGAAAAAGTAAATTATCATAACAGAACTATGGAACCCCATTCACCCATAACAGAGAAATTTCAGTCACAAGGAATGGCCGTAGGGGAACTGGCTGCTGCAACACTTCAGTATAGTGATAATGGTGCTGCTAACCTTCTCATGGAGAAATATATAAAAGGACCAGAGGGCATGACTCAGTTCATGAACAGTATTGGTGATACTAAGTTTAGGTTGGACCGATGGGAGTTGGACCTTAATAGTGCTATACCTGGAGATGAACGTGACACATCAACACCGAAGGCCGTGGCAGAAAGTCTGAATAAGTTAATATCAAATACCGTCTTAGACAACTACCATCAAGAGATATTCAAAAAGTGGATGATCGGTAATACTACAGGAGATAATAGAATAAGAGCTGCTGTGCCTGATGGTTGGGTTGTCGGTGATAAAACGGGAACTTGCGGAAAGTATGGCACAGCAAACGATCATGCGTTTATTTTACAAGGTAATAATGCTGCCCCTCTGATTTTATCTATATATACAACCAGAAAGGGAGAACATATGAAGCATGATGATGAGGTGATTGCTAAAGCAGCTAGGATTGCAATAGAAAATGTAAAGTGA"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Vibrio cholerae", "NCBI_taxonomy_id": "666", "NCBI_taxonomy_cvterm_id": "36789"}, "protein_sequence": {"GI": "ALU64000", "sequence": "MKRIAMYVALSISTSTAFADEHNKNMADIEAAFEGRVGVYAINTGSGKAYSYRANERFPLCSSFKAFLAAAVLKMDQDSPGVLLEKVNYHNRTMEPHSPITEKFQSQGMAVGELAAATLQYSDNGAANLLMEKYIKGPEGMTQFMNSIGDTKFRLDRWELDLNSAIPGDERDTSTPKAVAESLNKLISNTVLDNYHQEIFKKWMIGNTTGDNRIRAAVPDGWVVGDKTGTCGKYGTANDHAFILQGNNAAPLILSIYTTRKGEHMKHDDEVIAKAARIAIENVK"}}}}, "ARO_category": [], "ARO_name": "VCC-1", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "40367", "model_name": "VCC-1", "model_type_id": "40292"}, "2224": {"model_id": "2224", "ARO_accession": "3003686", "model_param": {"snp": {"param_value": {"3176": "Q142X"}, "param_type_id": "36301", "param_type": "resistance variant", "param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}, "ARO_description": "oprD is an outer membrane porin which facilitates the uptake of basic amino acids and imipenem in Pseudomonas aeruginosa.", "model_sequences": {"sequence": {"3421": {"dna_sequence": {"fmax": "1045314", "fmin": "1043982", "accession": "NC_002516.2", "strand": "-", "sequence": "TTACAGGATCGACAGCGGATAGTCGACGATCAGGCGGAACTCGTTCTGGTCGCCTTCGCCCTGGTCGGCGTTGGCACGGTGCCAGGCCTGGCGGATGCGGAACGACAGGTCCTTGGCCGGACCGGACTGGACCACGTACTTGGCTTCGAGGTTGGTTTCGTGGTGCTTGCCATCCTCGCCGTAGCCGTAGTTCTTATAGCCGACGTTGTTGTCAGACATCTTGGTGCCATCGATGTCCTTGCCATTGATATAGCGGACCATGAAAGTCAGGCCGGGAACGCCATAGGAGGCTAGGTTCAGGTCGTAGCGAGCCTGCCAGGATTTCTCGCCAGGGCCGTTGAAGTCGGAGTACTGGACAGAGTTGGCGAGGAAAATCGAGTCGCCACCTGCGCCAGAGCCGTTGCGGCCGAAGCCGATATAATCAAACGGCTGATCGCCATGGACCTTCTGGTAGGCCAAGGTGAAAGTGTGCGCATCCAGAGTGTAGGCTGCCGCCAGGGACCAAGTGGTGTTGCTGATGTCGCCGGCCTTGGCCTTGCCTTCATCGTTTGTGCGGTAGATGTTGAAATCGAAGCCCAGCGATTGGTCGGATGCCAGTGGGATGGTGTAGTTGCTGTTCAGGTAATACTGGCGATAGATGTCTTCGAGTTCGGCGCCGTACAGGGAGGCGCTGAGGTTATCGGTGATTGCGTAGCGGCCCCCAATGAAATCGGCGCTCTTGGCGGTCTCGCCTGCGTAGGTGGCATAGAGTTCGCCACGCGATTTGACGGTGGTCGGCTCCTTGCCCTCGGTGAAGTGGCCTGCCTCGAGGTCGAGCCCTTCGAATTCGCTGCTCTGCAGCTGGAAGCCGGTCGCGGTCTGCGGGAACAGGCGGCTGCCGCCAGCGGCGAAGACCGGGGCGGTCGGTTGCATCTCGCCCCACTTCAGCATGGTCTTGGAGATGCGCACCTTCACGGCGCCGCCGGCGCGGCTGTAGTCATCGCGCGGCTTGCCGTCGTTCATCACCGGCAGGTTGCCGGTGCCGGTCTTGTCGGAGGTGCCGTCGAGCTTCAGGCCCAGGTAGCCGAAGGCATCGACGCCGAAGCCCACAGTGCCTTGGGTGAAGCCGGATTCATAGGTGGTGAGGAAGCCTTGGGTCCAGTCGACGCGGTCCCCGCTGCCGCTCTTGCCGTCACGGTTGAAATAGTAGTTGCGGAGCAGCAGGTCGAGGCTGCTGTCTTCGATGAACCCCTTCGCTTCGGCCTGATCGCTGACGAATGCGTCGGCCACGGCGAACTGAGTGCTACCTGCGGAAACCGCCAGTGCAATGGCGCTCCACTTCATCACTTTCAT"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Pseudomonas aeruginosa PAO1", "NCBI_taxonomy_id": "208964", "NCBI_taxonomy_cvterm_id": "36804"}, "protein_sequence": {"GI": "NP_249649.1", "sequence": "MKVMKWSAIALAVSAGSTQFAVADAFVSDQAEAKGFIEDSSLDLLLRNYYFNRDGKSGSGDRVDWTQGFLTTYESGFTQGTVGFGVDAFGYLGLKLDGTSDKTGTGNLPVMNDGKPRDDYSRAGGAVKVRISKTMLKWGEMQPTAPVFAAGGSRLFPQTATGFQLQSSEFEGLDLEAGHFTEGKEPTTVKSRGELYATYAGETAKSADFIGGRYAITDNLSASLYGAELEDIYRQYYLNSNYTIPLASDQSLGFDFNIYRTNDEGKAKAGDISNTTWSLAAAYTLDAHTFTLAYQKVHGDQPFDYIGFGRNGSGAGGDSIFLANSVQYSDFNGPGEKSWQARYDLNLASYGVPGLTFMVRYINGKDIDGTKMSDNNVGYKNYGYGEDGKHHETNLEAKYVVQSGPAKDLSFRIRQAWHRANADQGEGDQNEFRLIVDYPLSIL"}}}}, "ARO_category": [], "ARO_name": "oprD", "model_type": "protein variant model", "model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "ARO_id": "40321", "model_name": "oprD", "model_type_id": "40293"}, "2222": {"model_id": "2222", "ARO_accession": "3003712", "ARO_description": "VEB-1b is a beta-lactamase that is found in Pseudomonas aeruginosa.", "model_sequences": {"sequence": {"3416": {"dna_sequence": {"fmax": "900", "fmin": "0", "accession": "AF324834.1", "strand": "+", "sequence": "ATGAAAATCGTAAAAAGGATATTATTAGTATTGTTAAGTTTATTTTTTACAGTTGAGTATTCAAATGCTCAAACTGACAACTTAACTTTGAAAATTGAGAATGTTTTAAAGGCAAAAAATGCCAGAATAGGAGTAGCAATATTCAACAGCAATGAGAAGGATACTTTGAAGATTAATAACGACTTCCATTTCCCGATGCAAAGCGTTATGAAATTTCCGATTGCTTTAGCCGTTTTGTCTGAGATAGATAAAGGGAATCTTTCTTTTGAACAAAAAATAGAGATTACCCCTCAAGACCTTTTGCCTAAAACGTGGAGTCCGATTAAAGAGGAATTCCCTAATGGAACAACTTTGACGATTGAACAAATACTAAATTATACAGTATCAGAGAGCGACAATATTGGTTGTGATATTTTGCTAAAATTAATCGGAGGAACTGATTCTGTTCAAAAATTCTTGAATGCTAATCATTTCACTGATATTTCAATCAAAGCAAACGAAGAACAAATGCACAAGGATTGGAATACCCAATATCAAAATTGGGCAACCCCAACAGCGATGAACAAACTGTTAATAGATACTTATAATAATAAGAACCAATTACTTTCTAAAAAAAGTTATGATTTTATTTGGAAAATTATGAGAGAAACAACAACAGGAAGTAACCGATTAAAAGGACAATTACCAAAGAATACAATTGTTGCTCATAAAACAGGGACTTCCGGAATAAATAATGGAATTGCAGCAGCCACTAATGATGTTGGGGTAATTACTTTACCGAATGGACAATTAATTTTTATAAGCGTATTTGTTGCAGAGTCCAAAGAAACTTCGGAAATTAATGAAAAGATTATTTCAGACATTGCAAAAATAACGTGGAATTACTATTTGAATAAATAA"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Pseudomonas aeruginosa", "NCBI_taxonomy_id": "287", "NCBI_taxonomy_cvterm_id": "36752"}, "protein_sequence": {"GI": "AAK14294.1", "sequence": "MKIVKRILLVLLSLFFTVEYSNAQTDNLTLKIENVLKAKNARIGVAIFNSNEKDTLKINNDFHFPMQSVMKFPIALAVLSEIDKGNLSFEQKIEITPQDLLPKTWSPIKEEFPNGTTLTIEQILNYTVSESDNIGCDILLKLIGGTDSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNKNQLLSKKSYDFIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGINNGIAAATNDVGVITLPNGQLIFISVFVAESKETSEINEKIISDIAKITWNYYLNK"}}}}, "ARO_category": [], "ARO_name": "VEB-1b", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "40366", "model_name": "VEB-1b", "model_type_id": "40292"}, "2223": {"model_id": "2223", "ARO_accession": "3003709", "model_param": {"snp": {"param_value": {"3173": "V44A", "3175": "Q10Z", "3174": "G46S", "3168": "G195E"}, "param_type_id": "36301", "param_type": "resistance variant", "param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}, "ARO_description": "MexZ is a transcriptional regulator of the mexXY multidrug transporter operon, which confers to aminoglycoside resistance on Pseudomonas aeruginosa.", "model_sequences": {"sequence": {"3420": {"dna_sequence": {"fmax": "2213309", "fmin": "2212676", "accession": "NC_002516.2", "strand": "+", "sequence": "GTGGCCAGGAAAACCAAAGAGGAATCCCAGAAAACCCGCGACGGCATACTCGATGCCGCCGAGCGGGTTTTCCTGGAAAAGGGCGTGGGCACCACTGCCATGGCCGACCTGGCGGACGCCGCCGGGGTTTCTCGCGGTGCGGTCTACGGCCACTACAAGAACAAGATCGAGGTCTGCCTGGCGATGTGCGACCGCGCCTTCGGCCAGATCGAGGTACCCGACGAAAACGCCAGGGTGCCGGCGCTGGATATCCTCCTGCGCGCCGGCATGGGCTTTCTCCGCCAGTGCTGCGAGCCCGGTTCGGTGCAGCGGGTGCTGGAGATCCTCTACCTCAAGTGCGAACGCAGCGACGAGAACGAGCCGCTGTTGCGCCGCCGCGAGCTGCTCGAGAAGCAGGGGCAACGCTTCGGCCTCCGGCAGATCCGCCGGGCGGTGGAACGCGGCGAACTGCCGGCGCGGCTGGACGTCGAGCTGGCCAGCATCTATCTGCAATCGCTCTGGGACGGCATCTGCGGCACCCTGGCCTGGACCGAGCGCCTGCGCGACGATCCCTGGAACCGCGCCGAACGCATGTTCCGCGCCGGCCTCGACAGCCTGCGCAGTTCTCCCTACCTGTTGCTGGCGGACGCCTGA"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Pseudomonas aeruginosa PAO1", "NCBI_taxonomy_id": "208964", "NCBI_taxonomy_cvterm_id": "36804"}, "protein_sequence": {"GI": "NP_250710.1", "sequence": "MARKTKEESQKTRDGILDAAERVFLEKGVGTTAMADLADAAGVSRGAVYGHYKNKIEVCLAMCDRAFGQIEVPDENARVPALDILLRAGMGFLRQCCEPGSVQRVLEILYLKCERSDENEPLLRRRELLEKQGQRFGLRQIRRAVERGELPARLDVELASIYLQSLWDGICGTLAWTERLRDDPWNRAERMFRAGLDSLRSSPYLLLADA"}}}}, "ARO_category": [], "ARO_name": "mexZ", "model_type": "protein variant model", "model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "ARO_id": "40363", "model_name": "mexZ", "model_type_id": "40293"}, "2220": {"model_id": "2220", "ARO_accession": "3000836", "ARO_description": "SoxR is a sensory protein that upregulates soxS expression in the presence of redox-cycling drugs. This stress response leads to the expression many multidrug efflux pumps. In Pseudomonas aeruginosa, which lacks SoxS, SoxR is able to directly upregulate the expression of the MexGHI-OpmD efflux pump.", "model_sequences": {"sequence": {"3413": {"dna_sequence": {"fmax": "2503895", "fmin": "2503424", "accession": "AE004091.2", "strand": "-", "sequence": "CTAGCCGTCGTGCTCGCGGCCCTCGGCGTCCAGCCAGTGCGCTCCCGGCCCCTCGGCGGAAAGCTGGTCGCCGGGGTTGCGCAACGGGCAGGCCTGGAGCGACAGGCAGCCGCAACCGATGCAGCCGTCCAGTTGGTCGCGCAACAGCAGCAGCTTGTCGATGCGCTCGGTGAGATCCTCCTTCCACTGCGCCGACAGGCGCGCCCAGTCCGCCGCGCTAGGGCTGCGCCCCGCCGGCAGGGTCTGCAGGGCGCGAGCGATCTCCGCGAGGGGAATGCCGACCCGCTGGGCGACCTTGATCACCACCACCCGGCGTAGCGTCTCGCGACTGAAGCGCCGCTGGTTGCCGGCGTTGCGCTGGCTGCTGATCAGCCCCTTGGTTTCGTAGAAATGCAGGGCGGAGACCGCCACGCCGGCACGCCTGGCCAGTTCGCCGACGCTCAGTTCACGAGATGCGCAGGAATTCTTCAT"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Pseudomonas aeruginosa PAO1", "NCBI_taxonomy_id": "208964", "NCBI_taxonomy_cvterm_id": "36804"}, "protein_sequence": {"GI": "AAG05661.1", "sequence": "MKNSCASRELSVGELARRAGVAVSALHFYETKGLISSQRNAGNQRRFSRETLRRVVVIKVAQRVGIPLAEIARALQTLPAGRSPSAADWARLSAQWKEDLTERIDKLLLLRDQLDGCIGCGCLSLQACPLRNPGDQLSAEGPGAHWLDAEGREHDG"}}}}, "ARO_category": {"36537": {"category_aro_name": "chloramphenicol resistance gene", "category_aro_cvterm_id": "36537", "category_aro_accession": "3000398", "category_aro_description": "Genes conferring resistance to chloramphenicol."}, "36590": {"category_aro_name": "gene modulating antibiotic efflux", "category_aro_cvterm_id": "36590", "category_aro_accession": "3000451", "category_aro_description": "Genes that directly or indirectly change rates of antibiotic efflux."}, "36241": {"category_aro_name": "fluoroquinolone resistance gene", "category_aro_cvterm_id": "36241", "category_aro_accession": "3000102", "category_aro_description": "Genes conferring resistance to fluoroquinolones."}, "36298": {"category_aro_name": "efflux pump conferring antibiotic resistance", "category_aro_cvterm_id": "36298", "category_aro_accession": "3000159", "category_aro_description": "Efflux proteins that pump antibiotic out of a cell to confer resistance."}, "35950": {"category_aro_name": "antibiotic resistant gene variant or mutant", "category_aro_cvterm_id": "35950", "category_aro_accession": "0000031", "category_aro_description": "Resistance to antibiotics is often conferred by single nucleotide polymorphisms (SNPs) and other mutations in target genes."}, "36611": {"category_aro_name": "tetracycline resistance gene", "category_aro_cvterm_id": "36611", "category_aro_accession": "3000472", "category_aro_description": "Genes conferring resistance to tetracycline antibiotics."}, "36522": {"category_aro_name": "rifampin resistance gene", "category_aro_cvterm_id": "36522", "category_aro_accession": "3000383", "category_aro_description": "Genetic determinants which confer resistance to rifampin."}, "36268": {"category_aro_name": "beta-lactam resistance gene", "category_aro_cvterm_id": "36268", "category_aro_accession": "3000129", "category_aro_description": "Genes conferring resistance to beta-lactams."}}, "ARO_name": "soxR", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "37216", "model_name": "soxR", "model_type_id": "40292"}, "2221": {"model_id": "2221", "ARO_accession": "3003711", "ARO_description": "VEB-1a is a beta-lactamase that is found in Pseudomonas aeruginosa.", "model_sequences": {"sequence": {"3415": {"dna_sequence": {"fmax": "900", "fmin": "0", "accession": "AF324833.1", "strand": "+", "sequence": "ATGAAAATCGTAAAAAGGATATTATTAGTATTGTTAAGTTTATTTTTTACAGTTGTGTATTCAAATGCTCAAACTGACAACTTAACTTTGAAAATTGAGAATGTTTTAAAGGCAAAAAATGCCAGAATAGGAGTAGCAATATTCAACAGCAATGAGAAGGATACTTTGAAGATTAATAACGACTTCCATTTCCCGATGCAAAGCGTTATGAAATTTCCGATTGCTTTAGCCGTTTTGTCTGAGATAGATAAAGGGAATCTTTCTTTTGAACAAAAAATAGAGATTACCCCTCAAGACCTTTTGCCTAAAACGTGGAGTCCGATTAAAGAGGAATTCCCTAATGGAACAACTTTGACGATTGAACAAATACTAAATTATACAGTATCAGAGAGCGACAATATTGGTTGTGATATTTTGCTAAAATTAATCGGAGGAACTGATTCTGTTCAAAAATTCTTGAATGCTAATCATTTCACTGATATTTCAATCAAAGCAAACGAAGAACAAATGCACAAGGATTGGAATACCCAATATCAAAATTGGGCAACCCCAACAGCGATGAACAAACTGTTAATAGATACTTATAATAATAAGAACCAATTACTTTCTAAAAAAAGTTATGATTTTATTTGGAAAATTATGAGAGAAACAACAACAGGAAGTAACCGATTAAAAGGACAATTACCAAAGAATACAATTGTTGCTCATAAAACAGGGACTTCCGGAATAAATAATGGAATTGCAGCAGCCACTAATGATGTTGGGGTAATTACTTTACCGAATGGACAATTAATTTTTATAAGCGTATTTGTTGCAGAGTCCAAAGAAACTTCGGAAATTAATGAAAAGATTATTTCAGACATTGCAAAAATAACGTGGAATTACTATTTGAATAAATAA"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Pseudomonas aeruginosa", "NCBI_taxonomy_id": "287", "NCBI_taxonomy_cvterm_id": "36752"}, "protein_sequence": {"GI": "AAK14293.1", "sequence": "MKIVKRILLVLLSLFFTVVYSNAQTDNLTLKIENVLKAKNARIGVAIFNSNEKDTLKINNDFHFPMQSVMKFPIALAVLSEIDKGNLSFEQKIEITPQDLLPKTWSPIKEEFPNGTTLTIEQILNYTVSESDNIGCDILLKLIGGTDSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNKNQLLSKKSYDFIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGINNGIAAATNDVGVITLPNGQLIFISVFVAESKETSEINEKIISDIAKITWNYYLNK"}}}}, "ARO_category": [], "ARO_name": "VEB-1a", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "40365", "model_name": "VEB-1a", "model_type_id": "40292"}, "2213": {"model_id": "2213", "ARO_accession": "3003700", "ARO_description": "opmE is an outer membrane factor protein that is part of the multidrug efflux pump MexPQ-OpmE.", "model_sequences": {"sequence": {"3407": {"dna_sequence": {"fmax": "5810", "fmin": "4334", "accession": "AB219524.1", "strand": "+", "sequence": "ATGAAGCCATACCTGCGGTCTTCGTTGAGCGCGCTGATCCTGCTGGGCGGCTGTGCCGCGGTGGGGCCCGACTATGCGCCGCCGAGCGCGTCCGCACCGGCCAGCTTCGGCGCGATGCCGGCGGGTATCGATGGCAGTGGCGTGGAGATCGAGTGGTGGCGCGGGTTCGACGAGCCAGCCCTGGAGTCTCTGATCCAGCGGGCGCTCGCGGCGAACCTCGACATCGCCCTTGCCGGCGCGCGCCTGGACGAAGCGAAGGCGCTGCTGCGCGAGAACCGCGAAGAGTTCCTGCCGCGCGGCGGCCCGGCGTTCGATTACCAGGCCCGGCGGCGCGGCGAGGTGGAAACACCGGCCGGCCAGCAGCGCGACATCGAGACCTATCGCGGCGCGCTGGATGCTTCCTGGGAAATCGACCTGTTCGGCCGGGTGCGGCGCTCGGTGGAGGCCGCCGAGGCGCAGGCGGGCTCGCGCGAGGCCCTGCTGCGCAACGTGCAGGCGAGCGTCGCGGCTACGGTTGCCATGTCCTGGTTCCAGCTACAGGGCATCGAGGCCGAACTTGCGGTGGTCCATGACATCGCCGGCAACCAGCGCGACAGCCTGGAGATGGTCGAACGCCTGGTCAGCGCCGGCTCCGCCCACGAGTTCGACCGGTTGCGCGCCGAAGCGTTATTGCACAACGTCGAGGCGGCCGTGCCCGACCTCGAACGGCGCCGCGCCGCCACCCGCAATGCGCTGGCCGTTCTCCTCGCGGAAGCCCCGCAGGCCTTCAGCCCGCCGGTCGCCCGTGCCTCCGGGGAAAGGCTGACGCTCCGCACCCTCGGGGTCGGCGACCCGGCGGGACTGCTGGCGCGTCGCGCTGACATCGCCGCGGCCGAACGCAACCTGGCGGCCGCGACCGCACGTATCGGCGTCGAGACCGCGGGGCTGTATCCGCAGGTCGAGGTACGCGGCTCGATCGGCCTGGTCGCCGGCAATCTCGATGCTTTGGACGAGAGTGGTACGTCCTTCAACGTCCTGAACCCGGTGATTCGCTGGGCGTTACTCGACCGCGGTCGCGTGTGGGCGCGGATCGCCGCCAGCGAAGCCCGTGCGCAGGAGGCATTGATCCTCTACGACCGGACGGTACTGCGCGCCCTGCAGGAGACCGATGATGCCTTCAACGGCTATGGCGCTGCCGCTGACAGGCTCCGCCTGCGCCTGCTCGAGGCGACGGCCAATCGCGAGGCGGCGCGCCTGGCCCGGGAGCGCTTCGTCCAGGGGGACGGCGAGTACCTGGACGTGCTCGAGGCGGAACGCTCGGACTACCTCAGCCGGCGCGCATTGAGCATCGCGCGCACCGAGCAGCGCCTTGCCGTCGTGGGTATCTACAAGGCGCTGGGGGGTGGCTGGGAGGCCTGCGCGGGGGCGCGGCGCTGTGGCGTGGCTACCGACGATACCTCTCCAGGCGTGGCACGGCAGCGCGACAGTCGCTCCTGA"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Pseudomonas aeruginosa", "NCBI_taxonomy_id": "287", "NCBI_taxonomy_cvterm_id": "36752"}, "protein_sequence": {"GI": "BAE06009.1", "sequence": "MKPYLRSSLSALILLGGCAAVGPDYAPPSASAPASFGAMPAGIDGSGVEIEWWRGFDEPALESLIQRALAANLDIALAGARLDEAKALLRENREEFLPRGGPAFDYQARRRGEVETPAGQQRDIETYRGALDASWEIDLFGRVRRSVEAAEAQAGSREALLRNVQASVAATVAMSWFQLQGIEAELAVVHDIAGNQRDSLEMVERLVSAGSAHEFDRLRAEALLHNVEAAVPDLERRRAATRNALAVLLAEAPQAFSPPVARASGERLTLRTLGVGDPAGLLARRADIAAAERNLAAATARIGVETAGLYPQVEVRGSIGLVAGNLDALDESGTSFNVLNPVIRWALLDRGRVWARIAASEARAQEALILYDRTVLRALQETDDAFNGYGAAADRLRLRLLEATANREAARLARERFVQGDGEYLDVLEAERSDYLSRRALSIARTEQRLAVVGIYKALGGGWEACAGARRCGVATDDTSPGVARQRDSRS"}}}}, "ARO_category": [], "ARO_name": "opmE", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "40352", "model_name": "opmE", "model_type_id": "40292"}, "2212": {"model_id": "2212", "ARO_accession": "3003699", "ARO_description": "MexQ is the inner membrane transporter of the multidrug efflux pump MexPQ-OpmE.", "model_sequences": {"sequence": {"3406": {"dna_sequence": {"fmax": "4338", "fmin": "1176", "accession": "AB219524.1", "strand": "+", "sequence": "ATGACATTCCCACGCTTCTTCATCGATAGGCCGATCTTCGCCATCGTTCTTTCGGTGCTGATGATGATCGGAGGCATCGTTTCGTTCTTCCAGTTGCCGCTGAGCGAATACCCGGCGGTGACGCCGCCGACCGTGCAGGTGACTACCGCCTATCCCGGCGCCAACCCCGACGTGATCGCGCAGACGGTGGCGACACCGCTGGAGCAGGCGATCACCGGGGTCGAGGGGATGCTGTACATGTCCTCGCAGTCGGCCACCGACGGGCGAATGATCCTGACCATCACCTTCGACCAGCACATCGATCCCGACATGGCCCAGATCCAGGTGCAGAACCGGGTCTCGCGGGTGCTCTCGCGCCTGCCCGACGAGGTGCAGCGGCAGGGCGTGGTCACCCAGAAGACCTCGCCGGACATCCTCATGGTGGTGCACCTGCTGTCGCCGGAGCAACGCTACGACCCGCTGTACATCTCGAACTACGCCTACCTCCAGGTGCGCGACGAACTGCTGCGCCTGCCGGGGATCAGCGATGTGGTGGTGTGGGGCGCCGGCGAGTACAGCATGCGCCTGTGGCTCGACCCCGACCTGATCGCCGCGCGCGGGCTGACGGCGGGCGAAGTGATCGCCGCGGTACGCGAACAGAACGTCCAGGTGGCGGCCGGCGCCGTCGGCCAGGCGCCGGACTCCACCGCGGCCTTCCAGGTCACGGTGAATACCCTCGGGCGGCTGAGCGACGAAGAGCAGTTCGGCGACATCATCGTCCGCACCGGCGCCGACGGCCAGGTGACGCGCCTGCGCGACGTCGCGCGGATCGAGATGGGCGGCGATGCCTATGCGCTGCGCAGCCTGCTGGACGGCGAGCCGGCGGTGGCCTTGCAGATCATCCAGAGCCCCGGAGCCAACGCGCTGGATACCGCCGAAGCGGTGCGTGCCACCGTGGCGAGGCTCGAAGGCAACTTCCCGGCCGGCCTGAGCGCGCGCATCGCCTACGACCCGACGGTGTTCGTCCGCGCTTCGTTGCAGACCGTGGCCACCACCCTGCTGGAGGCGATCCTGCTGGTCGTGGTGGTGGTGGTGCTGTTCCTGCGTAGCTGGCGTGCTTCGCTGATTCCGCTGATGGCCGTGCCGGTCTCGCTGGTCGGCACCTTCGCCGTCATGCACCTGATGGGTTTCTCGCTGAATACCCTGTCGTTGTTCGGCCTGGTGTTGTCGATCGGCATCGTCGTCGATGACGCCATCGTGGTGGTGGAAAACGTCGAGCGCCACATCGAGAACGGCGAGCCGCCGCTCCAGGCCGCGCGGCGTGCGATGGACGAGGTCACCGGGCCGATCATGGCGATCACCTCGGTGCTGGCGGCGGTGTTCATCCCCACGGCCTTTCTCAGTGGCCTGCAGGGCGAGTTCTATCGTCAGTTCGCCCTGACCATCGCCATCTCCACCATCCTGTCGGCGCTCAACTCGCTGACCCTCAGCCCGGCCCTGGCGGGCCTGCTGTTGCGTCCGCGGCCGGCCGGAGGTGCGGTGGCGGGGCGCTTCCAGCGACTGCTCCAGGTCCTCGGCCGACCGTTGCGAAATGCCCCCGAGGCCTACGGCAACGCGGTGCGCAAGGTGGTGCGGGTGAGCGGCCTGGCCCTGGTGGTGTATGGGGGCCTGCTTGGCCTGACCTGGGTCGGTTTCCAGGCGGTGCCGCCGGGCTTCGTGCCGATGCAGGACAAGTACTATCTGATCGGCATCGCCCAGTTGCCGAACGGAGCGTCGCTGGAGCGTACCGATGCGGTGGTCAGGCAGATGTCCCGGATCGGCCTCGACGAGCCGGGGGTGGAGAGCGTCGTGGCCTTCCCGGGCCTGTCGGTGAACGGTTTCGTCAACGTGCCGAACGCCGCGGTCATGTTCTTCATGCTCGATCCGTTCGAATCGCGCACCTCCGCCGATCTCGGCGCGCTGGCCATCGCCGGGCGCCTGCAAGCCAGGTTCGCCAGCATTCCCGACGGCTTCCTCGGGGTCTTCCCGCCGCCGCCGGTACCGGGGCTGGGAACCATCGGCGGCTTCAAGATGCAGGTCGAGGATCGCGGCGGCGCCGGGCTGGAAGCCCTGGCCAGGCAGACCCAGGTGCTGATGATGAAGGCCACTGAGTCCGGCCAGCTCGGGGGCTTGATGACCAGCTTCGATATCAATGCCCCGCAGCTCGAGGTGGTGGTCGACCGCACCAAGGTGAAGAGCCAGGGCGTTCGCCTGGCCGATGTGTTCGAGGCATTGCAGGTCTACCTCGGCTCGCTGTACATCAACGACTTCAACCGCTTCGGTCGCACCTACAAGGTCACTGCCCAGGCCGATGCGCCGCACCGCATGCAGGCCGAAGCCATCGGGCGCCTGCAGGTACGCAATGCCGCCGGGGCGATGTTGCCGCTGTCCTCGTTCGTCACCGTGACGCCCAGCTCCGGTCCCGACCGGGTGATCCACTACAACGGCTATCCGTCGGCGGATATCAGCGGCGGCGCGCTTCCCGGCGTCAGTTCGGGACAGGCGGTGGCGTTGATGGAGCGCCTGGCCGGCGAAGTGCTGCCCGAGGGCATGACCTTCGAATGGACCGACCTGACCTACCAGCAGAAGCTGGCCGGCAACAGCGCGCTGTTCATCTTCCCGCTGTGCGTGCTGCTGGCCTACCTGATCCTCGCCGCGCAGTACAACAGCTGGCTGTTGCCGCTGGCGGTCCTGCTGATCGTGCCGATGTGCCTGCTCAGCGCGATCGCCGGGGTGTGGCTGGTGGGCGGCGACAACAACGTGTTCGTCCAGATCGGGCTGGTGGTGCTGGTAGGCCTGGCGGCGAAGAACGCGATCCTGATCGTCGAGTTCGCCCGCACGCTGGAGGCCGAGGGCGCCCGTGCGCTGGAGGCGGTGGTCGAGGCTTGCCGCCTGCGCCTGCGGCCGATCCTGATGACCTCGCTGGCGTTCATCGCCGGCGTGGTGCCGTTGGTCATGGCCAGCGGCGCCGGAGCGGAAATGCGCCAGGCGATGGGCGTCGCGGTATTCGCCGGGATGCTCGGGGTGACGCTGTTCGGCCTGTTCCTCACGCCGGTGTTCTACGTACTGGTACGGGCACTGGCGGCGCGCCTGGAGCGACGCGCCGGCGGCAGCCTGGCGCATCTGGAGGGAGGCCGTCCATGA"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Pseudomonas aeruginosa", "NCBI_taxonomy_id": "287", "NCBI_taxonomy_cvterm_id": "36752"}, "protein_sequence": {"GI": "BAE06008.1", "sequence": "MTFPRFFIDRPIFAIVLSVLMMIGGIVSFFQLPLSEYPAVTPPTVQVTTAYPGANPDVIAQTVATPLEQAITGVEGMLYMSSQSATDGRMILTITFDQHIDPDMAQIQVQNRVSRVLSRLPDEVQRQGVVTQKTSPDILMVVHLLSPEQRYDPLYISNYAYLQVRDELLRLPGISDVVVWGAGEYSMRLWLDPDLIAARGLTAGEVIAAVREQNVQVAAGAVGQAPDSTAAFQVTVNTLGRLSDEEQFGDIIVRTGADGQVTRLRDVARIEMGGDAYALRSLLDGEPAVALQIIQSPGANALDTAEAVRATVARLEGNFPAGLSARIAYDPTVFVRASLQTVATTLLEAILLVVVVVVLFLRSWRASLIPLMAVPVSLVGTFAVMHLMGFSLNTLSLFGLVLSIGIVVDDAIVVVENVERHIENGEPPLQAARRAMDEVTGPIMAITSVLAAVFIPTAFLSGLQGEFYRQFALTIAISTILSALNSLTLSPALAGLLLRPRPAGGAVAGRFQRLLQVLGRPLRNAPEAYGNAVRKVVRVSGLALVVYGGLLGLTWVGFQAVPPGFVPMQDKYYLIGIAQLPNGASLERTDAVVRQMSRIGLDEPGVESVVAFPGLSVNGFVNVPNAAVMFFMLDPFESRTSADLGALAIAGRLQARFASIPDGFLGVFPPPPVPGLGTIGGFKMQVEDRGGAGLEALARQTQVLMMKATESGQLGGLMTSFDINAPQLEVVVDRTKVKSQGVRLADVFEALQVYLGSLYINDFNRFGRTYKVTAQADAPHRMQAEAIGRLQVRNAAGAMLPLSSFVTVTPSSGPDRVIHYNGYPSADISGGALPGVSSGQAVALMERLAGEVLPEGMTFEWTDLTYQQKLAGNSALFIFPLCVLLAYLILAAQYNSWLLPLAVLLIVPMCLLSAIAGVWLVGGDNNVFVQIGLVVLVGLAAKNAILIVEFARTLEAEGARALEAVVEACRLRLRPILMTSLAFIAGVVPLVMASGAGAEMRQAMGVAVFAGMLGVTLFGLFLTPVFYVLVRALAARLERRAGGSLAHLEGGRP"}}}}, "ARO_category": [], "ARO_name": "mexQ", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "40351", "model_name": "mexQ", "model_type_id": "40292"}, "2229": {"model_id": "2229", "ARO_accession": "3003714", "ARO_description": "PEDO-2 is a subclass B3 metallo-beta lactamase isolated from Pedobacter borealis exhibiting carbapenem resistance.", "model_sequences": {"sequence": {"3428": {"dna_sequence": {"fmax": "6675", "fmin": "5817", "accession": "KP109678", "strand": "+", "sequence": "ATGAAAAAAATATTTTTAATGGTTTTATTTTCTTGCAGTCTGTTGGGTTTTGCTCAAACAGTAACAGAGCCGGCTAATAATCCAAAAGAATGGTCTCAAGCTACAGAGCCATTTAGAATTGCAGGTAATCTATATTATGTTGGCACTTATGATTTAGCTTCTTATTTAATTGTAACAGAAAAAGGAAATATATTAATAAATACAGGTTTAGCTAATTCGCTTTCAATAATAAAAGAAAATATAAAAGCTTTGGGATTTGATTATAAATCAATCAAAATTTTGCTCTTAACCCAAGCTCATTTTGATCATTTGGGTGCGATGTCTGAGATTAAAAAAGAAACCGGTGCAAAACTTTATGTAGATGAGAAAGATGCGGACGCTCTTGAAACAGGCGGAAAATTGGATTATGAGCTTGGAAAATATGGCATAAGTTTCAAGCCTGTAAAACCTGATTTCCTATTGAAGAATAACGATAAGATTAAATTAGGCAACACTACTTTAACAATGCTTCATCATCCTGGGCATACTAAAGGATCGTGTAGTTTTATATTTGATACAAAAGATAAAAATTCTAGCTACAAAATTTTGATTGCCAATATGCCATCCATAATTGTTGATAGAAAATTCTCAGAAATAGCATCATATAAAGATATCCAAAAAGATTATACCGAAACTTTTAAAGCAATGAAAAAGCTTGACTTTGATCTTTGGGTTGCCTCTCATGCAAGTCAGTTTGAGCTCCATGATAAACGTAAATCAGGAGCCCCTTATAATCCAAAAATCTTTATGGATAAAAGTAAATTTTTCAAGAATCTTGAAGATCTGGAAAATATTTTCCTCGAAAAAATAAAAAATTAA"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Pedobacter sp. ALS-14", "NCBI_taxonomy_id": "1620221", "NCBI_taxonomy_cvterm_id": "40284"}, "protein_sequence": {"GI": "AJP77071", "sequence": "MKKIFLMVLFSCSLLGFAQTVTEPANNPKEWSQATEPFRIAGNLYYVGTYDLASYLIVTEKGNILINTGLANSLSIIKENIKALGFDYKSIKILLLTQAHFDHLGAMSEIKKETGAKLYVDEKDADALETGGKLDYELGKYGISFKPVKPDFLLKNNDKIKLGNTTLTMLHHPGHTKGSCSFIFDTKDKNSSYKILIANMPSIIVDRKFSEIASYKDIQKDYTETFKAMKKLDFDLWVASHASQFELHDKRKSGAPYNPKIFMDKSKFFKNLEDLENIFLEKIKN"}}}}, "ARO_category": [], "ARO_name": "PEDO-2", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "40368", "model_name": "PEDO-2", "model_type_id": "40292"}, "2216": {"model_id": "2216", "ARO_accession": "3003704", "ARO_description": "mexM is the membrane fusion protein of the MexMN-OprM multidrug efflux complex.", "model_sequences": {"sequence": {"3409": {"dna_sequence": {"fmax": "1179", "fmin": "21", "accession": "AB219523.1", "strand": "+", "sequence": "ATGCAGGCGTTGCGCAGTGGTGGGGGACGGGTCCTGGTGGGCGTGCTGGCGGCGGGCCTGGTCGCCTTCGGCGGTTGGGCATGGCTCGGCGGCGACGCCGGGGCGAAGGCGGCGCCCGCGCCGGCCAGGGTCCCGGTGATCGTGGCGCGGGTGGAGCGGCGCGACGTCGAGCAACAGGTCAGCGGCATCGGCACGGTGACTTCGTTGCACAACGTGGTGATCCGCACCCAGATCGACGGCCAGTTGACCCGCCTGCTGGTGAGCGAAGGGCAGATGGTCGAGGCGGGCGAGTTACTGGCGACCATCGATGACCGCGCCGTCGTCGCCGCGCTGGAGCAGGCGCAGGCCTCCAGGGCGAGCAACCAGGCCCAGCTGAAATCCGCCGAGCAGGACCTGCAACGCTACCGCAGCCTGTATGCCGAGCGTGCGGTGTCACGCCAACTGCTGGACCAGCAGCAGGCGACGGTCGACCAGTTGCGCGCGACCCTGAAGGCCAACGATGCCACCATCAACGCCGAGCGGGTGCGCCTGTCCTACACCCGGATCACCTCGCCGGTATCCGGCAAGGTCGGTATCCGCAACGTCGATGTCGGCAACCTGGTGCGGGTCGGCGACAGTCTCGGCCTGTTCAGCGTGACCCAGATCGCACCGATCTCCGTAGTCTTCTCCCTGCAACAGGAACAGTTGCTCCAGTTGCAGGCGCTGCTCGGCGGCGAGGCGGCGGTGCGCGCCTACAGCCGCGACGGCGGGAGCGCGCTGGGCGAGGGCCGGTTGCTGACCATCGACAACCAGATCGACAGTTCCACCGGCACCATCCGCGTGCGCGCCTCCTTCGATAACCGCCAGGCCCGGCTCTGGCCCGGGCAGTTCGTCGCGGTGAGCCTGCACACCGGGGTCCGGCGCGACCAGTTGGTGCTGTCGAGCAAGGCGGTGCGCCGCGGCCTGGAGGGCAATTTCGTCTACCGGGTCGCCGACGACCGGGTCGAGGCGGTGCCGGTGCGGGTGCTCCAGGACATCGACGGCCTCAGTGTGGTGGAAGGCCTGGCCAGCGGTGACCAGGTGGTGGTGGACGGCCACTCGCGGCTGATGCCCGGCGCCCTGGTCGATATCCAGGAGCCGCGCCCGAGCCTGGCCCAGGCCACGGAGCGGCGGCCGTGA"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Pseudomonas aeruginosa", "NCBI_taxonomy_id": "287", "NCBI_taxonomy_cvterm_id": "36752"}, "protein_sequence": {"GI": "BAE06005.1", "sequence": "MQALRSGGGRVLVGVLAAGLVAFGGWAWLGGDAGAKAAPAPARVPVIVARVERRDVEQQVSGIGTVTSLHNVVIRTQIDGQLTRLLVSEGQMVEAGELLATIDDRAVVAALEQAQASRASNQAQLKSAEQDLQRYRSLYAERAVSRQLLDQQQATVDQLRATLKANDATINAERVRLSYTRITSPVSGKVGIRNVDVGNLVRVGDSLGLFSVTQIAPISVVFSLQQEQLLQLQALLGGEAAVRAYSRDGGSALGEGRLLTIDNQIDSSTGTIRVRASFDNRQARLWPGQFVAVSLHTGVRRDQLVLSSKAVRRGLEGNFVYRVADDRVEAVPVRVLQDIDGLSVVEGLASGDQVVVDGHSRLMPGALVDIQEPRPSLAQATERRP"}}}}, "ARO_category": [], "ARO_name": "mexM", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "40358", "model_name": "mexM", "model_type_id": "40292"}, "2239": {"model_id": "2239", "ARO_accession": "3003721", "ARO_description": "ampC is a beta-lactamase isolated from Salmonella that confers resistance to cephalosporin", "model_sequences": {"sequence": {"3439": {"dna_sequence": {"fmax": "3520", "fmin": "2374", "accession": "NC_010259", "strand": "+", "sequence": "ATGATGAAAAAATCGTTATGCTGCGCTCTGCTGCTGACAGCCTCTTTCTCCACATTTGCTGCCGCAAAAACAGAACAACAGATTGCCGATATCGTTAATCGCACCATCACCCCGTTGATGCAGGAGCAGGCTATTCCGGGTATGGCCGTTGCCGTTATCTACCAGGGAAAACCCTATTATTTCACCTGGGGTAAAGCCGATATCGCCAATAACCACCCAGTCACGCAGCAAACGCTGTTTGAGCTAGGATCGGTTAGTAAGACGTTTAACGGCGTGTTGGGCGGCGATGCTATCGCCCGCGGCGAAATTAAGCTCAGCGATCCGGTCACGAAATACTGGCCAGAACTGACAGGCAAACAGTGGCAGGGTATCCGCCTGCTGCACTTAGCCACCTATACGGCAGGCGGCCTACCGCTGCAGATCCCCGATGACGTTAGGGATAAAGCCGCATTACTGCATTTTTATCAAAACTGGCAGCCGCAATGGACTCCGGGCGCTAAGCGACTTTACGCTAACTCCAGCATTGGTCTGTTTGGCGCGCTGGCGGTGAAACCCTCAGGAATGAGTTACGAAGAGGCAATGACCAGACGCGTCCTGCAACCATTAAAACTGGCGCATACCTGGATTACGGTTCCGCAGAACGAACAAAAAGATTATGCCTGGGGCTATCGCGAAGGGAAGCCCGTACACGTTTCTCCGGGACGACTTGACGCCGAAGCCTATGGCGTGAAATCCAGCGTTATTGATATGGCCCGCTGGGTTCAGGCCAACATGGATGCCAGCCACGTTCAGGAGAAAACGCTCCAGCAGGGCATTGCGCTTGCGCAGTCTCGCTACTGGCGTATTGGCGATATGTACCAGGGATTAGGCTGGGAGATGCTGAACTGGCCGCTGAAAGCTGATTCGATCATCAACGGCAGCGACAGCAAAGTGGCATTGGCAGCGCTTCCCGCCGTTGAGGTAAACCCGCCCGCCCCCGCAGTGAAAGCCTCATGGGTGCATAAAACGGGCTCCACTGGTGGATTTGGCAGCTACGTAGCCTTCGTTCCAGAAAAAAACCTTGGCATCGTGATGCTGGCAAACAAAAGCTATCCTAACCCTGTCCGTGTCGAGGCGGCCTGGCGCATTCTTGAAAAGCTGCAATAA"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Salmonella enterica subsp. enterica serovar Newport", "NCBI_taxonomy_id": "108619", "NCBI_taxonomy_cvterm_id": "35735"}, "protein_sequence": {"GI": "YP_001649321.1", "sequence": "MMKKSLCCALLLTASFSTFAAAKTEQQIADIVNRTITPLMQEQAIPGMAVAVIYQGKPYYFTWGKADIANNHPVTQQTLFELGSVSKTFNGVLGGDAIARGEIKLSDPVTKYWPELTGKQWQGIRLLHLATYTAGGLPLQIPDDVRDKAALLHFYQNWQPQWTPGAKRLYANSSIGLFGALAVKPSGMSYEEAMTRRVLQPLKLAHTWITVPQNEQKDYAWGYREGKPVHVSPGRLDAEAYGVKSSVIDMARWVQANMDASHVQEKTLQQGIALAQSRYWRIGDMYQGLGWEMLNWPLKADSIINGSDSKVALAALPAVEVNPPAPAVKASWVHKTGSTGGFGSYVAFVPEKNLGIVMLANKSYPNPVRVEAAWRILEKLQ"}}}}, "ARO_category": [], "ARO_name": "ampC", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "40375", "model_name": "ampC", "model_type_id": "40292"}, "2238": {"model_id": "2238", "ARO_accession": "3000496", "ARO_description": "VanXY is a protein with both D,D-carboxypeptidase and D,D-dipeptidase activity, found in Enterococcus gallinarum. It cleaves and removes the terminal D-Ala of peptidoglycan subunits for the incorporation of D-Ser by VanC. D-Ala-D-Ser has low binding affinity with vancomycin.", "model_sequences": {"sequence": {"3438": {"dna_sequence": {"fmax": "3011", "fmin": "2438", "accession": "AF162694", "strand": "+", "sequence": "ATGAACACATTACAATTGATCAATAAAAACCATCCATTGAAAAAAAATCAAGAGCCCCCGCACTTAGTGCTAGCTCCTTTTAGCGATCACGATGTTTACCTGCAGCCAGAAGTGGCAAAACAATGGGAACGACTCGTACGAGCAACCGGACTAGAAAAGGACATTCGTCTGGTAGATGGGTATCGTACGGAAAAAGAACAGCGACGCTTGTGGGAGTATTCTCTAAAAGAAAACGGGTTAGCTTATACCAAACAATTCGTTGCTTTGCCAGGTTGCAGTGAACATCAAATCGGTCTGGCCATTGATGTAGGACTAAAGAAACAAGAAGATGATGATCTTATCTGCCCTCATTTTCGAGATAGTGCTGCTGCTGATTTATTTATGCAGCAGATGATGAATTATGGCTTTATTCTACGCTATCCGGAAGATAAACAAGAGATCACCGGTATCAGTTATGAACCTTGGCATTTTCGTTATGTCGGGCTTCCCCATAGCCAAGTCATCACTGCCCAAAAATGGACTCTGGAAGAATACCATGATTACTTGGCTCAGACAGTGAGGCAGTTCGCATGA"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Enterococcus gallinarum", "NCBI_taxonomy_id": "1353", "NCBI_taxonomy_cvterm_id": "36781"}, "protein_sequence": {"GI": "AAF61331", "sequence": "MNTLQLINKNHPLKKNQEPPHLVLAPFSDHDVYLQPEVAKQWERLVRATGLEKDIRLVDGYRTEKEQRRLWEYSLKENGLAYTKQFVALPGCSEHQIGLAIDVGLKKQEDDDLICPHFRDSAAADLFMQQMMNYGFILRYPEDKQEITGISYEPWHFRYVGLPHSQVITAQKWTLEEYHDYLAQTVRQFA"}}}}, "ARO_category": {"36633": {"category_aro_name": "glycopeptide resistance gene", "category_aro_cvterm_id": "36633", "category_aro_accession": "3000494", "category_aro_description": "Genes conferring resistance to glycopeptides."}, "36021": {"category_aro_name": "gene conferring antibiotic resistance via molecular bypass", "category_aro_cvterm_id": "36021", "category_aro_accession": "3000012", "category_aro_description": "Genes involved in restructuring of the cell wall"}}, "ARO_name": "vanXY", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "36635", "model_name": "vanXY", "model_type_id": "40292"}, "2211": {"model_id": "2211", "ARO_accession": "3003698", "ARO_description": "MexP is the membrane fusion protein of the MexPQ-OpmE multidrug efflux complex", "model_sequences": {"sequence": {"3405": {"dna_sequence": {"fmax": "1180", "fmin": "22", "accession": "AB219524.1", "strand": "+", "sequence": "ATGAATCTCAGACACTTCATCCGCATCACCGCGACGCTAGGTGTCGCGGCCCTTATCGCTGGCTGCGGGGAATCGGCGCCGCCGGGGGCGGCGAGCGCCCCGCCAAGCGTTCCCGTCGCCGAGGTGGTGGTTCGCCCGGTGACACCCTACGCCGAGTTCACCGGCTCGCTGACCGCTGTCGAGCAGGTAGAACTGCGGCCGCGCGTCGCCGGCTACATCCAGGACGTTACGGTGCCGGAAGGCCGCCTGGTAGAGAAGGGCCAGCAACTGTTCCTCATCGACCCGCGCGTGTTCAAGGCGGCGCAGGATGCCGCCAGGGCACGCCTGCGCGAGGCCGAGGCCGCGGCGTTGCTGGCGCGCACCGAACACGAGCGAGCCGAGCTGCTGTATGCGCGGAAGGTCGTCGCCCGGGAGCGGCTCGACAGCGCCATCGCCTCGCGCAATGCCAGCAAGGCCCAGGTCGATGCGGCCAGGGCCGCCCTCGACGCGGCGCAACTGGATCTCGGCTTCACGCGGGTGACGGCACCGATCGGCGGGCGTGTCGGGCATATCCAGGTCACCGAGGGCAACTACGTCACCAATGGCGTCACCGCGCTGACCAGCATCGTTTCGGTCGATCCGCTGTACGTGTACTTCGATGTCGACGAGCGCACCTACCTGCAGGCCCTGGCGCCGACCCGCGGCAGGGAAGGCGAGCAGGCCCCCAGGGTCAAGGTGGCGCTGCTCACCGACGAGTCCTATGGACGAAGCAGTCGCCTCGATTTCCTCGCCAACGCCGCCGACCGCGGGACCGGCACGGTCCGGGTTCGGGCGGTGGTGGACAACCCGGACGGGCAACTGACGCCGGGGCTGTTCGCCAAGGTCAGGCTGGAGACCGGCAAGCCTCGCGCGCAGGTGCTGGTCGCCGACCATTCCATCGGCACCGACCAGGGCAGGCGCTATGTGCTGGTCGTCGACGAAGGCAACAAGACCCAGTACCGGCCGGTGGAACTCGGCCCGATGGTCGACGGCCTGCGGGTCGTCCGCCAGGGCCTGCAGCCGGGCGAGCGCATCGTCGTCAAGGGCCTGGTCCGGCCGGACATGCAGATCACACCGCGCCTTGCGGAAATCGATGGCACGCCCGTCGACCTGTCGAAGACCGTGGGGGCCGCACAATGA"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Pseudomonas aeruginosa", "NCBI_taxonomy_id": "287", "NCBI_taxonomy_cvterm_id": "36752"}, "protein_sequence": {"GI": "BAE06007.1", "sequence": "MNLRHFIRITATLGVAALIAGCGESAPPGAASAPPSVPVAEVVVRPVTPYAEFTGSLTAVEQVELRPRVAGYIQDVTVPEGRLVEKGQQLFLIDPRVFKAAQDAARARLREAEAAALLARTEHERAELLYARKVVARERLDSAIASRNASKAQVDAARAALDAAQLDLGFTRVTAPIGGRVGHIQVTEGNYVTNGVTALTSIVSVDPLYVYFDVDERTYLQALAPTRGREGEQAPRVKVALLTDESYGRSSRLDFLANAADRGTGTVRVRAVVDNPDGQLTPGLFAKVRLETGKPRAQVLVADHSIGTDQGRRYVLVVDEGNKTQYRPVELGPMVDGLRVVRQGLQPGERIVVKGLVRPDMQITPRLAEIDGTPVDLSKTVGAAQ"}}}}, "ARO_category": [], "ARO_name": "mexP", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "40350", "model_name": "mexP", "model_type_id": "40292"}, "2217": {"model_id": "2217", "ARO_accession": "3003705", "ARO_description": "MexN is the inner membrane transporter of the MexMN-OprM multidrug efflux complex.", "model_sequences": {"sequence": {"3410": {"dna_sequence": {"fmax": "4286", "fmin": "1175", "accession": "AB219523.1", "strand": "+", "sequence": "GTGACGCCGCGCGCCGGGATTTCCGGCTGGTGCGTACGGCACCCGATCGCCACCGCGCTGCTGACCCTGGCCTCGCTGCTGCTGGGGCTGCTGGCGTTCCTCCGGCTCGGTGTGGCGCCGTTGCCGGAGGCGGACTTCCCGACCATCCAGATCAACGCCTTGCTGCCCGGCGGTAGCCCGGAGACCATGGCCTCGTCGGTGGCCACCCCCTTGGAAGTGCAGTTCAGCGCGATTCCCGGGATCACCGAGATGACTTCCAGCAGCGCCCTGGGCACCACCACCCTGACCCTGCAGTTCAGCCTCGACAAGAGCATCGACGTCGCCGCCCAGGAGGTCCAGGCGGCGATCAACGCCGCGGCCGGGCGGCTGCCGGTGGACATGCCGAACCTGCCGACCTGGCGCAAGGTCAACCCGGCGGACAGCCCGATCATGATCCTGCGGGTCAACTCGGAGATGATGCCGCTGATCGAACTCAGCGATTACGCCGAGACCATCCTCGCCCGCCAGCTCAGCCAGGTGAACGGCGTGGGGCAGATCTTCGTGGTCGGCCAGCAGCGCCCGGCGATCCGCATCCAGGCCCAGCCGGAGAAGCTCGCCGCCTACCAGCTGACCCTGGCCGACCTGCGCCAGTCGTTGCAGTCGGCCAGCGTCAACCTGGCCAAGGGCGCGCTCTACGGCGAGGGGCGGGTGTCGACCCTCGCGGCCAACGACCAGTTGTTCAACGCCAGCGACTATGACGACCTGGTGGTCGCCTACCGCCAGGGCGCGCCGGTGTTCCTCAAGGACGTGGCGCGGATCGTCTCGGCGCCCGAGGACGACTACGTGCAGGCCTGGCCGAACGGCGTGCCCGGGGTGGCGCTGGTGATCCTGCGCCAGCCTGGGGCGAACATCGTCGATACCGCCGACGCGATCCAGGCCGCGCTGCCACGCCTGCGCGAGATGCTCCCGGCGACCATCGAGGTAGACGTGCTCAACGACCGCACCCGGACCATCCGCTCGTCGTTGCACGAGGTCGAACTGACCCTGCTGCTGACCATTGGCCTGGTGGTGCTGGTGATGGGCCTGTTCCTCCGCCAGCTGTCGGCGACCCTGATCGTCGCCACGGTGCTGGCGGTGTCCCTGAGCGCCAGCTTCGCGGCGATGTACGTGCTCGGCTTCACCCTCAACAACCTGACCCTGGTGGCGCTGATCATCGCTGTCGGCTTCATCGTCGACGACGCCATCGTGGTCGTGGAGAACATCCACCGACACCTGGAAGCGGGCGCCTCGAAGGTCGAGGCGGCGCTCAAGGGCGCGGCGGAGATCGGCTTTACCGTGATTTCCATCAGCTTCTCGCTGATCGCCGCGTTCATTCCCCTGCTGTTCATGGGCGGGATCGTCGGCCGGCTGTTCCGCGAATTCGCGGTCAGCGTGACGGTGGCGATCCTGATCTCGGTGGTCGCTTCGCTGACCCTGGCGCCGATGCTGGCTTCGCGCTTCATGCCGGCATTGCGGCATGCCGAAGCGCCGAGAAAGGGCTTCGCCGAATGGCTGACCGGCGGCTACGAACGCGGCCTGCGCTGGGCGCTCGGGCACCAGCGGCTGATGCTGGTCGGCTTCGCCTTTACCGTGCTGGTGGCGGTGGCCGGCTACGTCGGGATTCCCAAGGGTTTCTTCCCCTTGCAGGACACCGCCTTCGTCATCGGCACGAGCCAGGCTGCCGAGGATATCTCCTACGACGACATGGTCGCCAAGCACCGGCAACTGGCCGAGATCATCGCCAGCGACCCGGCGGTGCAGAGCTACAACCATGCGGTGGGCGTCACCGGCGGTAGCCAGAGCCTGGCCAACGGACGTTTCTGGATCGTCCTCAAGGACCGTGGCGAGCGCGATGTCTCGGTCGGCGAGTTCATCGACCGGCTGCGCCCGCAACTGGCCAAGGTGCCGGGAATCATGCTCTACCTGCGCGCGGCGCAGGACATCAACCTCAGTTCCGGACCCTCGCGGACCCAGTACCAGTACGCCCTGCGCAGCAGCGACAGCACCCAGCTGGCGCTCTGGGCGCAACGCCTCACCGAGCGCCTGAAGCAGGTGCCGGGGCTGATGGATGTGTCCAACGACCTGCAGGTCGGCGCCAGCGTCACCGCGCTGGACATCGACCGGGTGGCCGCGGCGCGTTTCGGCCTCAGCGCCGAGGATGTCAGCCAGACCCTCTACGACGCCTTCGGCCAGCGCCAGGTCGGCGAGTACCAGACCGAGGTCAACCAGTACAAGGTGGTCCTCGAACTCGATGCGCGCCAGCGCGGCCGCGCGGAAAGCCTGGACTGGTTCTACCTGCGCTCGCCGCTGAGCGGCGAGATGGTCCCGCTGTCGGCCATCGCCAAGGTCGCGGCGCCGCGCTCCGGGCCGCTGCAGATCAACCACAACGGCATGTTCCCGGCGGTCAACCTGTCCTTCAACCTGGCTGCCGGGGTGTCCCTCGGCGAGGCGGTGCAGGCGGTGCAGCGCGCCCAGGAGGAGATCGGCATGCCCTCGACCATTATCGGCGTGTTCCAGGGCGCGGCGCAGGCCTTCCAGAGCTCGCTGGCCTCGCAACCGCTGCTGATCCTCGCCGCGCTGATCGCGGTGTACATCATCCTCGGCGTGCTCTACGAGAGTTTCGTACATCCGCTGACGATCCTCTCGACCCTGCCCTCGGCGGGGATCGGCGCGGTGTTCCTGCTCTGGGCCTGGGGCCAGGACTTCTCGATCATGGCGCTGATCGGCATCGTGCTGCTGATCGGCATCGTCAAGAAGAACGGCATCCTCATGGTCGACTTCGCCATCGTCGCCCAGCGCGAGCAGGGCATGAGCGCGGAGCAGGCGATCTACCAGGCCTGCCTGACCCGTTTCCGGCCGATCATGATGACCACCCTGGCCGCGCTGCTGGGCGCGATACCCCTGATGATCGGCTTCGGCACCGGTTCCGAGCTGCGCCAGCCTCTGGGCATCGCGGTGGTCGGCGGGCTGCTGGTGAGCCAGGTGCTGACCCTGTTCAGCACGCCGGTGGTATACCTGGCCCTGGAGCGGCTGTTCCACCGGCGCGGGACGACGACCTCGGACGGCGGAACCGCTGGGGCGACGGCGACATGA"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Pseudomonas aeruginosa", "NCBI_taxonomy_id": "287", "NCBI_taxonomy_cvterm_id": "36752"}, "protein_sequence": {"GI": "BAE06006.1", "sequence": "MTPRAGISGWCVRHPIATALLTLASLLLGLLAFLRLGVAPLPEADFPTIQINALLPGGSPETMASSVATPLEVQFSAIPGITEMTSSSALGTTTLTLQFSLDKSIDVAAQEVQAAINAAAGRLPVDMPNLPTWRKVNPADSPIMILRVNSEMMPLIELSDYAETILARQLSQVNGVGQIFVVGQQRPAIRIQAQPEKLAAYQLTLADLRQSLQSASVNLAKGALYGEGRVSTLAANDQLFNASDYDDLVVAYRQGAPVFLKDVARIVSAPEDDYVQAWPNGVPGVALVILRQPGANIVDTADAIQAALPRLREMLPATIEVDVLNDRTRTIRSSLHEVELTLLLTIGLVVLVMGLFLRQLSATLIVATVLAVSLSASFAAMYVLGFTLNNLTLVALIIAVGFIVDDAIVVVENIHRHLEAGASKVEAALKGAAEIGFTVISISFSLIAAFIPLLFMGGIVGRLFREFAVSVTVAILISVVASLTLAPMLASRFMPALRHAEAPRKGFAEWLTGGYERGLRWALGHQRLMLVGFAFTVLVAVAGYVGIPKGFFPLQDTAFVIGTSQAAEDISYDDMVAKHRQLAEIIASDPAVQSYNHAVGVTGGSQSLANGRFWIVLKDRGERDVSVGEFIDRLRPQLAKVPGIMLYLRAAQDINLSSGPSRTQYQYALRSSDSTQLALWAQRLTERLKQVPGLMDVSNDLQVGASVTALDIDRVAAARFGLSAEDVSQTLYDAFGQRQVGEYQTEVNQYKVVLELDARQRGRAESLDWFYLRSPLSGEMVPLSAIAKVAAPRSGPLQINHNGMFPAVNLSFNLAAGVSLGEAVQAVQRAQEEIGMPSTIIGVFQGAAQAFQSSLASQPLLILAALIAVYIILGVLYESFVHPLTILSTLPSAGIGAVFLLWAWGQDFSIMALIGIVLLIGIVKKNGILMVDFAIVAQREQGMSAEQAIYQACLTRFRPIMMTTLAALLGAIPLMIGFGTGSELRQPLGIAVVGGLLVSQVLTLFSTPVVYLALERLFHRRGTTTSDGGTAGATAT"}}}}, "ARO_category": [], "ARO_name": "mexN", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "40359", "model_name": "mexN", "model_type_id": "40292"}, "2228": {"model_id": "2228", "ARO_accession": "3003670", "ARO_description": "PEDO-1 is a subclass B3 metallo-beta lactamase isolated from Pedobacter roseus exhibiting resistance to carbapenems.", "model_sequences": {"sequence": {"3429": {"dna_sequence": {"fmax": "5179", "fmin": "4318", "accession": "KP109677", "strand": "+", "sequence": "ATGAAAATTAAATTTATTTTTTGCCTCTTGCTTTTTCCGCTCTTTGTATTTTCACAAAATGTACAAGAACCTACCGATACGCCAAAAGAGTGGTCGGCTGCTTATGCCCCATTCCGCATTGTTGGGAATGTTTATTATGTTGGCACTTACGATCTGGCCTGCTACCTTATTACCACTCCGAAAGGAAATATACTGATCAATACCGGACTGCGTTCCTCGGCTGCGCAGATCAAAAAAAACGTGGAACTTTTGGGCTTTAACTTTAAAGACATCAAAATCCTGCTGACCACACAGGCACATTACGACCATTTGGGTGCTATGGCGGAGATCAAGAAACTTACTGGTGCAAAAATGATGGTTGATGAAAAAGATGCCAGTGTGATGAAGGATGGCGGCCGTACGGATTACGCACTGGGTAACGGAAAAACAACCTACGCTCCTATTATACCAGACCGTTTATTAAAGGATGGAGATCAGATCCAGCTCGGAAATACCAGTATTGTAATGCTCCACCACCCCGGCCATACTAAAGGATCATGCAGTTTTATGCTTAAAACTAAAGATGAAACAAGAGACTATTCGGTGCTGATTGCGAATATGCCCAGTATTGTTACCGAAAAAAAGTTTTCTGAAATACCAGCTTATCCGCAAATTGAAAAAGATTACGCCTATACTTTAAGTTCGCTCAAAAAATTATCATTTGATATCTGGTTGTCGTCTCATGCAAGCCAGTTTTGTCTGCACGAGAAACATAAACCTGGCGATAAATATAATCCTACCGCTTTTATAGATCGTGCAGGATACGATAAGGTATTAAACAGCCTTCAGCTCGAATTTGATAAAAAGATTGGCAAGAAATAG"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Pedobacter sp. SI-33", "NCBI_taxonomy_id": "1620222", "NCBI_taxonomy_cvterm_id": "40283"}, "protein_sequence": {"GI": "AJP77059", "sequence": "MKIKFIFCLLLFPLFVFSQNVQEPTDTPKEWSAAYAPFRIVGNVYYVGTYDLACYLITTPKGNILINTGLRSSAAQIKKNVELLGFNFKDIKILLTTQAHYDHLGAMAEIKKLTGAKMMVDEKDASVMKDGGRTDYALGNGKTTYAPIIPDRLLKDGDQIQLGNTSIVMLHHPGHTKGSCSFMLKTKDETRDYSVLIANMPSIVTEKKFSEIPAYPQIEKDYAYTLSSLKKLSFDIWLSSHASQFCLHEKHKPGDKYNPTAFIDRAGYDKVLNSLQLEFDKKIGKK"}}}}, "ARO_category": {"36696": {"category_aro_name": "antibiotic inactivation enzyme", "category_aro_cvterm_id": "36696", "category_aro_accession": "3000557", "category_aro_description": "Enzyme that catalyzes the inactivation of an antibiotic resulting in resistance.  Inactivation includes chemical modification, destruction, etc."}, "36268": {"category_aro_name": "beta-lactam resistance gene", "category_aro_cvterm_id": "36268", "category_aro_accession": "3000129", "category_aro_description": "Genes conferring resistance to beta-lactams."}}, "ARO_name": "PEDO-1", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "40288", "model_name": "PEDO-1", "model_type_id": "40292"}, "2215": {"model_id": "2215", "ARO_accession": "3003702", "model_param": {"snp": {"param_value": {"3166": "E91K", "3167": "S87W", "3165": "S87L"}, "param_type_id": "36301", "param_type": "resistance variant", "param_description": "A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s)."}}, "ARO_description": "Point mutation in Pseudomonas aeruginosa parC resulting in fluoroquinolone resistance also requiring a gyrA mutation.", "model_sequences": {"sequence": {"3408": {"dna_sequence": {"fmax": "2416", "fmin": "151", "accession": "AB003428.1", "strand": "+", "sequence": "ATGAGCGAATCCCTCGATCTGAGCCTGGAAGGGGTCGAACGCCGGTCGTTGGCCGAGTTCACCGAGCAGGCCTATCTGAACTATTCCATGTACGTGATCATGGACCGCGCCCTGCCGCATATCGGCGACGGCCTGAAACCGGTGCAGCGACGCATCGTCTACGCCATGAGCGAACTGGGGCTGGATGCCGATTCCAAGCACAAGAAGTCGGCGCGCACCGTCGGCGACGTGCTCGGCAAGTTCCACCCGCACGGCGACTCGGCCTGCTACGAGGCCATGGTGCTGATGGCGCAGCCGTTCTCCTATCGCTATCCGCTGGTGGACGGCCAGGGCAACTGGGGGGCTCCGGACGATCCCAAGTCCTTCGCCGCCATGCGTTATACCGAGGCGCGCCTGTCGCGCTATTCCGAGGTGCTGCTCAGCGAACTGGGCCAGGGTACCGTGGACTGGGTACCGAACTTCGACGGCACCCTCGACGAGCCGGCCGTGCTGCCGGCCCGCCTGCCCAACCTGCTGCTCAACGGCACCACCGGCATCGCGGTGGGCATGGCCACCGACGTGCCGCCGCACAACCTGCGGGAAGTCGCGTCGGCCTGCGTGCGCCTGCTCGACCAGCCGGGCGCGACGGTCGCCGAATTGTGCGAACACGTGCCGGGCCCGGACTTCCCCACCGAAGCCGAGATCATCACCCCGCGCGCCGACCTGCAGAAGGTCTACGAGACCGGCCGCGGTTCGGTGCGCATGCGCGCGGTGTACCGCTTCGAGGACGGCGATATCGTCATCCACGCCCTGCCGCACCAGGTGTCCGGTTCCAAGGTGCTGGAACAGATCGCCGGGCAGATGCAGGCCAAGAAGCTGCCGATGGTGGCCGACCTGCGCGACGAGTCGGACCACGAGAACCCGACCCGCATCGTCATCATCCCGCGTTCGAACCGGGTCGATGTCGAAGAGCTGATGACCCATCTGTTCGCCACCACCGACCTGGAGACCAGCTACCGGGTCAACCTGAACATCATCGGCCTCGACGGCAAGCCGGCAGTCAAGGACCTGCGCCAGTTGCTCTCGGAGTGGCTGCAGTTCCGCATCGGCACCGTGCGTCGACGCCTGCAGTTCCGCCTGGACAAGGTCGAGCGCCGCCTGCATCTGCTGGATGGCTTGCTGATCGCCTTCCTCAACCTCGACGAGGTGATCCACATCATCCGCACCGAGGACCAGCCCAAGGCGGTGCTGATGGAGCGCTTCGAACTCAGCGAGGTGCAGGCCGACTACATCCTCGACACCCGCCTGCGCCAGTTGGCACGCCTGGAAGAGATGAAGATCCGCGGCGAGCAGGAAGAGTTGCTGAAGGAGCAGAAGCGCCTGCAGACCCTGCTCGGCAGCGAGGCCAAGCTGAAGAAGCTGGTGCGCGAGGAGCTGATCAAGGACGCCGAGACCTACGGCGACGACCGCCGTTCGCCGATCGTCGCCCGCGCCGAGGCCCGCGCGCTGTCGGAAACCGAGCTGATGCCCACCGAACCGGTGACCGTGGTGCTCTCGGAAAAAGGCTGGGTGCGTTGCGCCAAGGGCCACGACATCGACGCCGCCGGCCTCTCCTACAAGGCCGGCGACGGCTTCAAGGCCGCCGCGCCGGGACGCTCGAACCAGTATGCGGTGTTCATCGACTCCACCGGGCGCAGCTACTCGCTGCCGGCCCACAGCCTGCCGTCCGCGCGAGGCCAGGGCGAGCCACTCAGCGGCCGGCTGACGCCGCCGCCGGGGGCCAGCTTCGAATGCGTGCTGCTGCCGGACGACGATGCGCTGTTCGTGATCGCTTCCGACGCCGGCTATGGTTTCGTGGTCAAGGGCGAGGACCTGCAGGCCAAGAACAAGGCCGGCAAGGCCCTGCTCAGCCTGCCCAACGGCTCCGCCGTGGTGGCGCCGCGCCCGGTGCGCGATGTGGAGCAGGATTGGCTGGCGGCCGTGACGACCGAGGGCCGTCTGCTATTGTTCAAGGTCTCCGACCTGCCGCAGCTCGGCAAGGGCAAGGGCAACAAGATCATCGGCATCCCCGGCGAACGCGTGGCCAGCCGCGAGGAATACCTCACCGACCTGGCTGTTCTGCCAGCCGGGGCGACGTTGGTCCTGCAGGCCGGAAAGCGTACCCTGTCGCTCAAGGGCGACGACCTGGAACACTACAAGGGGGAGCGAGGCCGGCGAGGCAACAAGCTGCCGCGCGGTTTCCAGCGCGTCGACAGCCTGCTGGTGGATATTCCGCCACAGGATTGA"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Pseudomonas aeruginosa", "NCBI_taxonomy_id": "287", "NCBI_taxonomy_cvterm_id": "36752"}, "protein_sequence": {"GI": "BAA37152.1", "sequence": "MSESLDLSLEGVERRSLAEFTEQAYLNYSMYVIMDRALPHIGDGLKPVQRRIVYAMSELGLDADSKHKKSARTVGDVLGKFHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTEARLSRYSEVLLSELGQGTVDWVPNFDGTLDEPAVLPARLPNLLLNGTTGIAVGMATDVPPHNLREVASACVRLLDQPGATVAELCEHVPGPDFPTEAEIITPRADLQKVYETGRGSVRMRAVYRFEDGDIVIHALPHQVSGSKVLEQIAGQMQAKKLPMVADLRDESDHENPTRIVIIPRSNRVDVEELMTHLFATTDLETSYRVNLNIIGLDGKPAVKDLRQLLSEWLQFRIGTVRRRLQFRLDKVERRLHLLDGLLIAFLNLDEVIHIIRTEDQPKAVLMERFELSEVQADYILDTRLRQLARLEEMKIRGEQEELLKEQKRLQTLLGSEAKLKKLVREELIKDAETYGDDRRSPIVARAEARALSETELMPTEPVTVVLSEKGWVRCAKGHDIDAAGLSYKAGDGFKAAAPGRSNQYAVFIDSTGRSYSLPAHSLPSARGQGEPLSGRLTPPPGASFECVLLPDDDALFVIASDAGYGFVVKGEDLQAKNKAGKALLSLPNGSAVVAPRPVRDVEQDWLAAVTTEGRLLLFKVSDLPQLGKGKGNKIIGIPGERVASREEYLTDLAVLPAGATLVLQAGKRTLSLKGDDLEHYKGERGRRGNKLPRGFQRVDSLLVDIPPQD"}}}}, "ARO_category": [], "ARO_name": "Pseudomonas aeruginosa gyrA and parC conferring resistance to fluoroquinolone", "model_type": "protein variant model", "model_description": "A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants.", "ARO_id": "40355", "model_name": "Pseudomonas aeruginosa parC conferring resistance to fluoroquinolone", "model_type_id": "40293"}, "2231": {"model_id": "2231", "ARO_accession": "3003716", "ARO_description": "CPS-1 is a subclass B3 metallo-beta lactamase isolated from Chyseobacterium piscium exhibiting carbapenem resistance.", "model_sequences": {"sequence": {"3431": {"dna_sequence": {"fmax": "2201", "fmin": "1328", "accession": "KP109675", "strand": "+", "sequence": "ATGAGAAACCTGACACTTTTATTTTTACTATGCCTATCTTTTTTTGGAACTGCACAAACCGTAACAGAGCCTAAAAATAATCCGGCAGAATGGTCAAAAGACTATGAACCTTTCAAAATTGTGGGGAATTTATATTATGTAGGAACTTACGATCTTGCATCTTATCTTATCGTGACCGATAAAGGCAATATTTTGATCAACACAGGTTTGGCGGATTCTTATTCTACCATTAAAAAAAATATCGAAAAGTTTGGTTTTAAGTATAAAGATATCAAAATTCTTACCTTAACGCAGGCACATTATGATCACATGGGAGCAATGGCTCAAATAAAAAAAGAAACCGGTGCAAAACTTTATGTTGACGAAAAAGATGCTGCAGAACTTAAAAGTGGTGGAAAATCTGACTACGAAATGGGAAAATACGGCGTTACTTTCGAACCTGTGCATCCTGATTTTCTTTTGAAAAACAATGCTAAAATAAAATTGGGAAATACGGTATTAACCTTGCTTCATCATCCCGGTCATACAAAAGGATCTTGCAGTTTCTTATTTGAAACCAAAGAAGGAAACAAAAATTACAAAGTTTTGATCGCCAATTTACCTTCAATTATTATTGACCATAAATTTTCTGATGTAAAGAAATATCCTACCATTCAGAAAGATTATGGATACACTTTTGAGGCCATGAAAAAAATAAATTTCGATGTTTGGGTAGCTTCGCATGCAAGTCAGTTTGATCTTCATAAAAAGCGGAAAGAAGGAGATTCTTACAATCCGAAATTGTTTATGGATAAAGAAAATTATTTTAAAAGGCTTAAAGATCTGGAAAACGATTATCTGGAAAAAGTAAAAGAAGATTCAGCGAAAAAATAA"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Chryseobacterium sp. Stok-1", "NCBI_taxonomy_id": "1620218", "NCBI_taxonomy_cvterm_id": "40281"}, "protein_sequence": {"GI": "AJP77054", "sequence": "MRNLTLLFLLCLSFFGTAQTVTEPKNNPAEWSKDYEPFKIVGNLYYVGTYDLASYLIVTDKGNILINTGLADSYSTIKKNIEKFGFKYKDIKILTLTQAHYDHMGAMAQIKKETGAKLYVDEKDAAELKSGGKSDYEMGKYGVTFEPVHPDFLLKNNAKIKLGNTVLTLLHHPGHTKGSCSFLFETKEGNKNYKVLIANLPSIIIDHKFSDVKKYPTIQKDYGYTFEAMKKINFDVWVASHASQFDLHKKRKEGDSYNPKLFMDKENYFKRLKDLENDYLEKVKEDSAKK"}}}}, "ARO_category": [], "ARO_name": "CPS-1", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "40370", "model_name": "CPS-1", "model_type_id": "40292"}, "2230": {"model_id": "2230", "ARO_accession": "3003715", "ARO_description": "PEDO-3 is a class B1 metallo-beta lactamase isolated from Pedobacter kyungheensis exhibiting resistance to carbapenems.", "model_sequences": {"sequence": {"3427": {"dna_sequence": {"fmax": "2974", "fmin": "2260", "accession": "KP109679", "strand": "+", "sequence": "CTACTTTTTCTCCCTCAATAGCTTTAGGGTATGGTCTAGAGATTCCCTGTTTCCCCAGGCAGCGTGTCCGGTAATAACAATTTTGGTATCAGGATATTTCTGTTTTAACTTTTCGATGCTTTTTGGCCATGCGGCTAAATCGGATTCTCCAATATAGCCCAAATCATTGGCTTCGATGCTTTTAATCAGGCAGCCACCGAATAAAACTTTGTCTTTTGGAAACCAAACTACCAGATTATCCTTTGTATGCCCCTTGCCGGCATAGTAGGTGTTTATTTTATATTGTCCCACTGTAAAAGTAGTGTCGTTGGTAAAGGTGTAGGCTGCGCGTGGCTCTTTATTAGTTTTCAGAATTTCGTCGGTTAATTTATTGGTATAGGTTTTTATGCCCTTACTTTTAAAGAACGCTAAACCGCCTGCGCGGTCGCCATGCGAATGTGTGGCAATGGCCAGCACTACTTTTTGGTGATGTTTGGTCTGAATAGAGTCTAAAAAGGGCTGGAACTGCGTAGCATCCCAAGGGGCATCGATTACTACAACACCTTTATTGGTAACCAGGTAAACCGCATTTGCATCTGTTAAAGCGCCTTTGTAGGTATTGTATGTGGTGTAAACATAAAGATCGCCAGTTAAATGTTTGATTTTTATTTTTGGATTTTGCGCGAAAGAGGCAAAGGCAGATAAACAAAGTAAAAAGGAAAGAAGATAACGCAT"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Pedobacter sp. Stok-3", "NCBI_taxonomy_id": "1620223", "NCBI_taxonomy_cvterm_id": "40285"}, "protein_sequence": {"GI": "AJP77076", "sequence": "MRYLLSFLLCLSAFASFAQNPKIKIKHLTGDLYVYTTYNTYKGALTDANAVYLVTNKGVVVIDAPWDATQFQPFLDSIQTKHHQKVVLAIATHSHGDRAGGLAFFKSKGIKTYTNKLTDEILKTNKEPRAAYTFTNDTTFTVGQYKINTYYAGKGHTKDNLVVWFPKDKVLFGGCLIKSIEANDLGYIGESDLAAWPKSIEKLKQKYPDTKIVITGHAAWGNRESLDHTLKLLREKK"}}}}, "ARO_category": [], "ARO_name": "PEDO-3", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "40369", "model_name": "PEDO-3", "model_type_id": "40292"}, "2219": {"model_id": "2219", "ARO_accession": "3003710", "ARO_description": "MexL is a specific repressor of mexJK transcription and autoregulates its own expression.", "model_sequences": {"sequence": {"3412": {"dna_sequence": {"fmax": "4121107", "fmin": "4120468", "accession": "AE004091.2", "strand": "+", "sequence": "ATGTCAGAATCCACCTCCTCCGTCGGTCCCGGCCGGCCCAAGGACCCGGCCAAACGGGAAGCCATTCTCGAGGCGGCCAAGCGCCTGTTCCTCTGCAACGGCTACGACGGCAGCAGCATGGAAGCCATCGCCTCGGAAGCCGGCGTTTCCAAGCTCACCGTCTACAGCCACTTCACCGACAAGGAAACCCTGTTCAGCGAAGCGGTGAAGGCCAAGTGCGCCGAGCAGCTTCCCGCCCTGTACTTCCAGCTGGCCGAAGGCGCGCCACTGGAAAAGGTCCTGCTGAATATCGCCCGCGGCTTCCACCGGCTGATCAACAGCCACGAGGCGATCGCCCTGACCCGCCTGATGGCCGCGCAGGCCGGGCAGAACCCCAAGCTTTCCGAGCTGTTCTTCGAGGCCGGGCCGAAGCAGGTGATCGACGAGATGGAACGCCTCCTCGAGCAGGCCCGCCGCAGCGGCAAGCTGGCGTTCCCGGACGCGCGCCACGCCGCCGAACACTTCTTCATGCTGGTCAAGGGCTGCGCCAATTACCGTCTGTTGATCGGCTGCGCCGAACCGCTGGACGAGGCCGAAGGCGAGCGGCACGTGGAAGAAGTGGTGGCGCTGTTCCTGCGCGCCTTCGCCGCGGGCGGCTGA"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Pseudomonas aeruginosa PAO1", "NCBI_taxonomy_id": "208964", "NCBI_taxonomy_cvterm_id": "36804"}, "protein_sequence": {"GI": "NP_252368.1", "sequence": "MSESTSSVGPGRPKDPAKREAILEAAKRLFLCNGYDGSSMEAIASEAGVSKLTVYSHFTDKETLFSEAVKAKCAEQLPALYFQLAEGAPLEKVLLNIARGFHRLINSHEAIALTRLMAAQAGQNPKLSELFFEAGPKQVIDEMERLLEQARRSGKLAFPDARHAAEHFFMLVKGCANYRLLIGCAEPLDEAEGERHVEEVVALFLRAFAAGG"}}}}, "ARO_category": [], "ARO_name": "mexL", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "40364", "model_name": "mexL", "model_type_id": "40292"}, "2232": {"model_id": "2232", "ARO_accession": "3003717", "ARO_description": "ESP-1 is a subclass B3 metallo-beta lactamase isolated from Epilithonimonas tenax conferring resistance to carbapenems.", "model_sequences": {"sequence": {"3432": {"dna_sequence": {"fmax": "2515", "fmin": "1642", "accession": "KP109681", "strand": "+", "sequence": "ATGAAAAAACTTACCCTAATACTTTCACTGATCATTGCCTTTTTCGGATATGCACAAACCGTAACAGAACCAACCAATCATTCTGCAGAATGGTCGCAACCTTACGAGCCATTCAGAATTGTCGGGAATTTGTATTACGTTGGAACTTATGATTTGGCTTCGTATCTCATTGTGACGGAAAAGGGAAATATCCTTATCAACACAGGTTTGGCGGATTCTTATCCTCAAATAAAAGCGAATATCGAGAAACTCGGATTCAAATACAAAGACACCAAAATCCTGACTTTGACACAAGCGCATTTTGACCATATGGGCGCAATGGCCGATATCAAAGCGGAAACCGGCGCAAAACTTTATGTAGACGAAGCAGATGCTGCGGAACTGAAATCAGGCGGAAAATCGGATTACGAACTGGGAAAATATGGTGTGACTTTCAAACCCTTAACGCCGGATTTTCTTCTGAAAAATAATGGTAAAATAAAATTAGGAAATACCACCTTGACCTTGCTTCATCATCCTGGTCACACAAAAGGTTCGTGCAGTTTTATCTTCGAAACCAAAGATGAAAATCGAAAATATAAAGTTGTGATCGCCAATATGCCATCCATCATCATCGATCATAAATTTTCTGATGTGAAAACTTATCCTTCAATTCAGAAAGATTATGCTTACACTTTGGAGGCGATGAAAAAACTGGATTTCGATGTTTGGGTAGCTTCGCACGCCAGCCAATTCGATCTTCATAAAAAAAGAAAAGAAGGCGATGCTTACAACCCGAAACTATTTATGGATAAAGAGAATTATTTTAAAAGACTGAAAGATTTGGAAGATGATTATCTGGAGAAAGTGAAAGAAGAAAATAAACCAGAATAA"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Epilithonimonas sp. Stok-2", "NCBI_taxonomy_id": "1620219", "NCBI_taxonomy_cvterm_id": "40287"}, "protein_sequence": {"GI": "AJP77085", "sequence": "MKKLTLILSLIIAFFGYAQTVTEPTNHSAEWSQPYEPFRIVGNLYYVGTYDLASYLIVTEKGNILINTGLADSYPQIKANIEKLGFKYKDTKILTLTQAHFDHMGAMADIKAETGAKLYVDEADAAELKSGGKSDYELGKYGVTFKPLTPDFLLKNNGKIKLGNTTLTLLHHPGHTKGSCSFIFETKDENRKYKVVIANMPSIIIDHKFSDVKTYPSIQKDYAYTLEAMKKLDFDVWVASHASQFDLHKKRKEGDAYNPKLFMDKENYFKRLKDLEDDYLEKVKEENKPE"}}}}, "ARO_category": [], "ARO_name": "ESP-1", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "40371", "model_name": "ESP-1", "model_type_id": "40292"}, "2235": {"model_id": "2235", "ARO_accession": "3003720", "ARO_description": "SPG-1 is a subclass B3 metallo-beta lactamase isolated from Spingomonas sp.", "model_sequences": {"sequence": {"3435": {"dna_sequence": {"fmax": "2112", "fmin": "1254", "accession": "KP109680", "strand": "+", "sequence": "TCAGCGCCGATCCGCATTCGCCGCTTGCTGCTTCGCCAGCGTCGCATCGAAAGCCTTCTCCGCCAGATCGACCTGGCGTGACAATTCGTTCGGATCGACAAAGGCGTCGGTGGCACCCGCCTGCGCCCTGGCGCGTTTTTCATCGAGCGCGAAAGCCTCGGCGTGGAAGCTCAGGAAGATATCTGCCTTCAACGCGCGGAGTTTCGCAAAGCTGGCACGGAAATCGGCGGCGGCGTTCGGATAATTTATATTATTGATAAGATTTTGGCCGGCGACACTGATACTCGATGTGAAGATCACATTCTTGCTGCCAATGCGGGTCGTCCAGCTCGTCGCGCCTTTTGTATGGCCGGGTGTCAGGATGGCGACGAGCGCGATCGGGCCGAGCGTCAGCCGGTCGCCGTCGCCGATCACACGATCGACCTTCACTGCCGGAAAGTCCGCGATATCGGTGCGGCCGATGGTGGTACCTGCTTCGAGATCGGGCTTGTCCGCAACGTTTGCGACCATTTGCGCGCCGGTCAGCCGCTTGAGTTCGGCCAGTCCACCGGCGTGATCGACATGCGAATGGTTGCTGAGCAGATATTTCACATCGGACAGTTTGAAGCCCAGTTTGCGGATGTTCGCGGCGATCAGCGGCGCGCTTTCCGGCAGAGCGCCGTCGATCAGCACATGGCCGCGCGGCCCGGCGATCAGATAGGCCGAAAGCCCGCTGGTGCCGACATAATAGAGATTGCCGGTGATGCGGAATGGCTCGCGCGGCCCGTTCCATTTCGCGCGCTGCTCGGCCGATTGGGCGAGGGCGCCGGATGGGGCTGTCATGGCGAGCGCGGATGCGAGCAGTATCAGGGGGCGCAT"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Sphingomonas sp. ALS-13", "NCBI_taxonomy_id": "1620224", "NCBI_taxonomy_cvterm_id": "40286"}, "protein_sequence": {"GI": "AJP77080", "sequence": "MRPLILLASALAMTAPSGALAQSAEQRAKWNGPREPFRITGNLYYVGTSGLSAYLIAGPRGHVLIDGALPESAPLIAANIRKLGFKLSDVKYLLSNHSHVDHAGGLAELKRLTGAQMVANVADKPDLEAGTTIGRTDIADFPAVKVDRVIGDGDRLTLGPIALVAILTPGHTKGATSWTTRIGSKNVIFTSSISVAGQNLINNINYPNAAADFRASFAKLRALKADIFLSFHAEAFALDEKRARAQAGATDAFVDPNELSRQVDLAEKAFDATLAKQQAANADRR"}}}}, "ARO_category": [], "ARO_name": "SPG-1", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "40374", "model_name": "SPG-1", "model_type_id": "40292"}, "2234": {"model_id": "2234", "ARO_accession": "3003719", "ARO_description": "MSI_OXA is an OXA-85-like class D beta lactamase isolated from Massilia oculi.", "model_sequences": {"sequence": {"3434": {"dna_sequence": {"fmax": "1841", "fmin": "1022", "accession": "KP109676", "strand": "+", "sequence": "ATGAGTCACACGTTCATCATCGACCGACTTGGAGCATCCATGATCAAGCAAATTCTCGCAGCACTGTTGTTGATCAGCCCGCTGCTGGCGCAGGCCGCCGAATGGAAGGAAAGCGCGCAGGTGGCGCGCCTGTTCAAGCAGGAAGGCGTGAGCGGCACCTTCGTCGTCTACGACGTGGCCGCCGACAGCTACACGGTGCATGACCGCCAGCGCGCCAACACGCGCTTCATTCCGGCGTCGACCTTCAAGATCCCGAACACGCTGATCGCGCTGGCGCATGGCGCGGTGGCCAACGTCGACGAAGTGGTGCCGTATGGCGGCAAGCCGGTAGCGCGGCCCGAGTGGGCGCGCGACATGGGGCTGCGCGAGGCGATCCGGATCTCGAACGTGCCGGTGTACCAGGAAGTGGCGCGGCGCGTGGGCCTGGACCGGATGCGCTCGGAGCTGGTCCGGATGAAGTACGGGAACATGCAGACCGGGACCGTGGTGGACCGGTTCTGGCTCGATGGGCCTTTGAAGATCAGCGCGGTGGAGCAGACCGAATTTTTGACCAAGCTGGCGCAGGGTACGCTGCCGTTCACCAACGTGGCGATGGCGGCGGTGCGCGAGATCAGCCGTCAGGATGGAGCGCCCGAGCTGTATGCCAAGACCGGGTGGGGCAGTCGGCCGGGCGAGGCCGATATCGGGTGGTGGGTCGGTTGGCTGAAGAAGGATGGCAAGCTGTATGCATTTGCGCTGAATATGGATCTTCCCGATGGTGCGCAGGACAAGCGGGTGTCGCTGGCGAAGGCGGCGTTGCGGGAACTGGGCCTGCTGTAG"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Massilia sp. SB1-3", "NCBI_taxonomy_id": "1620220", "NCBI_taxonomy_cvterm_id": "40282"}, "protein_sequence": {"GI": "AJP77058", "sequence": "MSHTFIIDRLGASMIKQILAALLLISPLLAQAAEWKESAQVARLFKQEGVSGTFVVYDVAADSYTVHDRQRANTRFIPASTFKIPNTLIALAHGAVANVDEVVPYGGKPVARPEWARDMGLREAIRISNVPVYQEVARRVGLDRMRSELVRMKYGNMQTGTVVDRFWLDGPLKISAVEQTEFLTKLAQGTLPFTNVAMAAVREISRQDGAPELYAKTGWGSRPGEADIGWWVGWLKKDGKLYAFALNMDLPDGAQDKRVSLAKAALRELGLL"}}}}, "ARO_category": [], "ARO_name": "MSI-OXA", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "40373", "model_name": "MSI-OXA", "model_type_id": "40292"}, "2237": {"model_id": "2237", "ARO_accession": "3000002", "ARO_description": "vanW is an accessory gene, with unknown function, found on vancomycin resistance operons.", "model_sequences": {"sequence": {"3437": {"dna_sequence": {"fmax": "3713", "fmin": "2978", "accession": "AF253562", "strand": "+", "sequence": "ATGAAATTTGACGGCAATAGATACGCAAAAAAGACATCTGAGAAATTGTTACCAAACACAGTATTTGAAACATCATCACTTATGCTAAATGAAAATAGTGGATTTGATATGAAGTACCAAATCAATAAGGTACACAACCTAAAACTTGCCGCAAAAACAATCAATAAAGTGATTATTGAGCCGAAAGAAACATTTTCATTTTGGCAGCTTGTACGATGGGCAGACCGTCACGAGAAATATAAGGACGGATTAAATCTTGTTAATGGAAAGATTGTAGGCTCTTATGGCGGAGGTTTGTGTCAATTGAGTAATATGCTATTTTGGCTTTTTTTACACACGCCGCTTGTTATTGTCGAGCGACACGGACACGCAGTTGAGTCTTTCCCATCAACAACCGAAGAGATGCCCCGCCGGAACGAAGCTACGATTAACGAAGGTTGGTTAGACCTAAAACCCCGAAAAAAAACGAACATACTTTCCAGATTGAGATTAGTTTTGATGACAACTTTAGTATGGTGCAATTTTGTCGCAAAGCTCGTAAATATTGATATACGGTTTTTATTCGTCTGTTTCCTATTTCAAGCGAGGGAAAAAGTATATCAAATAGCTTCTGTTTGTCGTACAGAAAAAGACAAAATGACTGGTAGTCAGACGGAAAAAGAATTGTATGTCAACCAATGTAAAATAGCCTATAAGCTACCCGATGGTGTAAAAATTGAAGAAAGAGGTGTGTAA"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Enterococcus faecalis", "NCBI_taxonomy_id": "1351", "NCBI_taxonomy_cvterm_id": "35918"}, "protein_sequence": {"GI": "AAF71280", "sequence": "MKFDGNRYAKKTSEKLLPNTVFETSSLMLNENSGFDMKYQINKVHNLKLAAKTINKVIIEPKETFSFWQLVRWADRHEKYKDGLNLVNGKIVGSYGGGLCQLSNMLFWLFLHTPLVIVERHGHAVESFPSTTEEMPRRNEATINEGWLDLKPRKKTNILSRLRLVLMTTLVWCNFVAKLVNIDIRFLFVCFLFQAREKVYQIASVCRTEKDKMTGSQTEKELYVNQCKIAYKLPDGVKIEERGV"}}}}, "ARO_category": {"36633": {"category_aro_name": "glycopeptide resistance gene", "category_aro_cvterm_id": "36633", "category_aro_accession": "3000494", "category_aro_description": "Genes conferring resistance to glycopeptides."}, "36021": {"category_aro_name": "gene conferring antibiotic resistance via molecular bypass", "category_aro_cvterm_id": "36021", "category_aro_accession": "3000012", "category_aro_description": "Genes involved in restructuring of the cell wall"}}, "ARO_name": "vanW", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "36011", "model_name": "vanW", "model_type_id": "40292"}, "2236": {"model_id": "2236", "ARO_accession": "3000372", "ARO_description": "VanT is a membrane bound serine racemase, converting L-serine to D-serine. It is associated with VanC, which incorporated D-serine into D-Ala-D-Ser terminal end of peptidoglycan subunits that have a decreased binding affinity with vancomycin. It was isolated from Enterococcus gallinarum.", "model_sequences": {"sequence": {"3436": {"dna_sequence": {"fmax": "5104", "fmin": "3007", "accession": "AF162694", "strand": "+", "sequence": "ATGAAAAATAAAGGAATCGATCAATTTCGTGTGATTGCAGCCATGATGGTGGTTGCGATCCATTGTCTTCCCCTTCACTATTTATGGCCAGAAGGCGATATCCTAATCACATTGACGATTTTTCGAGTAGCTGTTCCTTTCTTTTTTATGATCAGTGGTTACTATGTGTTTGCAGAACTTGCTGTGGCCAATAGTTATCCTTCGCGACAACGAGTATTCAACTTTATCAAAAAACAGCTAAAAGTCTATCTATTAGCCACACTAATGTTTTTACCATTAGCACTCTATAGTCAAACGATCGGCTTCGATCTACCAGTTGGAACATTAGTACAAGTACTTTTGGTCAATGGCATTCTTTATCATCTTTGGTACTTTCCGGCTTTGATTACTGGGAGCCTGCTCCTAACAAGTTTGCTGATACATGTCTCCTTCAAAAAAGTGTTCTGGCTTGCGGCTGGATTGTACCTGATTGGATTAGGTGGTGATAGTTGGTTTGGACTGATCCAACAGACACCAATCGAACCATTCTATACTGCTGTGTTCCACCTATTAGATGGTACCCGCAACGGTATTTTCTTTACACCATTGTTTTTGTGCTTAGGTGTGCTGGTCAGAAAACAATCAGAGAAAAGAAGTTTATCCAAAACAGCTCTCTTCTTTTTGATCAGTCTTATCGGATTGCTTATTGAGAGTGCGTACTTGCATGGGTTTTCTATACCTAAACATGACAGTATGTATCTCTTCTTGCCTGTTGTACTCTTTTTCTTATTTCCGCTGATCTTGCGCTGGCATCCCCACAGGACTTGGAAGCATCCAGGACAGCTATCTTTGTGGCTTTACCTTTTACATCCTTATACAATTGCCGGCACACACTTTTTGAGCCAAAAAATCAGCATTCTGCAAAACAATCTAATCAACTATTTGGTTGTTTTGATCTTGACGATTGGATTCATTTGCCTCTTTTTAAGACAAAAACACTCATGGTTTAGACACAAACAAACAACGCCCGTTAAAAGGGCCGTAAAAGAATTCTCAAAGACAGCCCTTTTGCATAATCTACAGGAGATCCAGCGGATCATCTCACCGAAAACAAAAGTGATGGCAGTCGTTAAAGCCGATGCCTACGGCTGTGGTGCCAAGGAAGTTGCTCCTGTTTTAGAACAAGCCGGAATTGATTTTTTTGCGGTGGCTACGATTGATGAAGGTATTCGATTGCGGAAAAATGCTGTCAAAAGCCCCATCTTGGTCTTGGGATATACCTCTCCAAAACGCATAAAAGAACTTCGTCGCTACTCATTGACCCAATCGATCATCAGCGAAGGTCATGCTGTAGCATTGTCACAAAGAAAAGTAGCGATTGACTGTCATTTAGCCATCGATACTGGGATGCATCGGTTAGGTGTAACACCGACTATCGATTCGATTCTTTCGATTTTCGATTTGCCCTTCTTGACGATCAGTGGTGTTTATTCTCATCTTGGTTCGGCAGATCGCTTAAATCCTGATAGTATGATTCGCACTCAGAAGCAGATTGCCTGCTTCGATCAGATTCTCCTAGAGTTGGATCAGAGACAGATTTCTTATGGTATCACACACTTACAAAGCAGTTATGGTATTTTGAATTATCCAGACTTAAACTATGATTATGTGCGTCCGGGGATTTTATTGACAGGATCCCTCAGTGATACGAACGAGCCTACAAAACAACGAGTAAGCTTACAGCCTATTCTGACCCTCAAAGCACAGTTGATCACTAAGCGAGTCGTTGCCAAAGGGGAAGCGATCGGTTATGGGCAAACCGCCGTCGCGAATCAAGAAACAACTGTTGGTGTTGTGAGCATCGGCTATTGTGACGGACTGCCCCGTTCTCTATCAAATCAAGAGTTTTGTCTTTCCTATCGCGGTCAGTCCTTGCCGCAGATCGGCTTGATCTGCATGGACATGCTTTTGATAGACTTGAGCCATTGTCCTACGATCCCAATTGAAAGTGAAATTGAAATTCTGACAGATTGGAGCGATACTGCCGAGCAAGTACAAACTATAACCAATGAGTTGATTTGTCGGATCGGTCCACGAGTCAGTGCTAGGATCAAATAG"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Enterococcus gallinarum", "NCBI_taxonomy_id": "1353", "NCBI_taxonomy_cvterm_id": "36781"}, "protein_sequence": {"GI": "AAD22403", "sequence": "MKNKGIDQFRVIAAMMVVAIHCLPLHYLWPEGDILITLTIFRVAVPFFFMISGYYVFAELAVANSYPSRQRVFNFIKKQLKVYLLATLMFLPLALYSQTIGFDLPVGTLVQVLLVNGILYHLWYFPALITGSLLLTSLLIHVSFKKVFWLAAGLYLIGLGGDSWFGLIQQTPIEPFYTAVFHLLDGTRNGIFFTPLFLCLGVLVRKQSEKRSLSKTALFFLISLIGLLIESAYLHGFSIPKHDSMYLFLPVVLFFLFPLILRWHPHRTWKHPGQLSLWLYLLHPYTIAGTHFLSQKISILQNNLINYLVVLILTIGFICLFLRQKHSWFRHKQTTPVKRAVKEFSKTALLHNLQEIQRIISPKTKVMAVVKADAYGCGAKEVAPVLEQAGIDFFAVATIDEGIRLRKNAVKSPILVLGYTSPKRIKELRRYSLTQSIISEGHAVALSQRKVAIDCHLAIDTGMHRLGVTPTIDSILSIFDLPFLTISGVYSHLGSADRLNPDSMIRTQKQIACFDQILLELDQRQISYGITHLQSSYGILNYPDLNYDYVRPGILLTGSLSDTNEPTKQRVSLQPILTLKAQLITKRVVAKGEAIGYGQTAVANQETTVGVVSIGYCDGLPRSLSNQEFCLSYRGQSLPQIGLICMDMLLIDLSHCPTIPIESEIEILTDWSDTAEQVQTITNELICRIGPRVSARIK"}}}}, "ARO_category": {"36633": {"category_aro_name": "glycopeptide resistance gene", "category_aro_cvterm_id": "36633", "category_aro_accession": "3000494", "category_aro_description": "Genes conferring resistance to glycopeptides."}, "36021": {"category_aro_name": "gene conferring antibiotic resistance via molecular bypass", "category_aro_cvterm_id": "36021", "category_aro_accession": "3000012", "category_aro_description": "Genes involved in restructuring of the cell wall"}}, "ARO_name": "vanT", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "36511", "model_name": "vanT", "model_type_id": "40292"}, "2233": {"model_id": "2233", "ARO_accession": "3003718", "ARO_description": "MSI-1 is a subclass B3 metallo-beta lactamase isolated from Massilia oculi conferring resistance to carbapenems.", "model_sequences": {"sequence": {"3433": {"dna_sequence": {"fmax": "1026", "fmin": "0", "accession": "KP109676", "strand": "+", "sequence": "ATGGGCGCACGATCGTGTTCGCGCGCATGGTGCTGCAGCCGCGCGACCCGGAGCGCGCCGCCGGGCCGGCGCTCAGGCAGGCTTTCCTGCGCGCGTTGCCGGCGACCCTCGACAGGCTGTAATCCTTCCTCTACTCCACCCATCACGGGAGACATCATGAAGCACATCCGCCTCGCCTGCGTCGCGGCCGGACTGGTCGCGGCCGCATCCTCCGTCAGCGCCATCGGCGCCGACTGGAACGCGCCGCAGGAACCGTTCGCCCTGTTCGGCAACAGCTACTACGTCGGCCCGCACGGCGTGGCCTCGGTCTTGATCACGTCGAATCAGGGTCACATCCTGATCGACGGCGGCAGCGACAAATCGCCGCCGCAGATCGCCGCGCGCATCCGCCAGCTCGGCTTCAAGCCGGAAGACATCCGCTTCATCCTGGTCTCGCACGAGCACATCGACCATGCGGGCGGTGTCGCCGAGCTGCAGCGCCTGTCGAACGCCGAGGTGCTGGCCGGCGCCGCCGCGGTGCCGGTGCTGCATAGCGGCGAGGCCGGTCGCAACGATCCGCAATACGGCGGCCTGCCGAAGATGGCGCCGGTGGCGCGGGTGCGCGCGGTGCGCGACGGCGAGGTGGTCAAACTCGGGCCGCTGGCGGTGACGATGCACGCCACGCCGGGCCATACGCAGGGTGGCGCCAGCTGGACCTGGCAATCAAACGAAGGCGGACGCACGGCCAACATGGTGTATGCCGACAGCCTGACGGCGTTCGGATCCGGGGGCTTTCGCTACAGCGGCGATGCGCGCTATCCGAGCGCGCGCGCCGACGTCGAGCGATCGATCGCGAAGGTCGCCGCGCTGCCGTGCGACATCCTGGTGTCGGCGCATCCGGAAGTGAGCGAGCTGTGGACCCGGTACGAGCGGCGCGCGGCGCAAGGCAACGCCGCGTTCATCGACGCCGGCGCCTGCAAGGCCTATGCCGTCAAGGCCCGCGTGAAGCTGCAGGAACAACTGGCCAGGGAAACGGCCAAGCCATGA"}, "NCBI_taxonomy": {"NCBI_taxonomy_name": "Massilia sp. SB1-3", "NCBI_taxonomy_id": "1620220", "NCBI_taxonomy_cvterm_id": "40282"}, "protein_sequence": {"GI": "AJP77057", "sequence": "MGARSCSRAWCCSRATRSAPPGRRSGRLSCARCRRPSTGCNPSSTPPITGDIMKHIRLACVAAGLVAAASSVSAIGADWNAPQEPFALFGNSYYVGPHGVASVLITSNQGHILIDGGSDKSPPQIAARIRQLGFKPEDIRFILVSHEHIDHAGGVAELQRLSNAEVLAGAAAVPVLHSGEAGRNDPQYGGLPKMAPVARVRAVRDGEVVKLGPLAVTMHATPGHTQGGASWTWQSNEGGRTANMVYADSLTAFGSGGFRYSGDARYPSARADVERSIAKVAALPCDILVSAHPEVSELWTRYERRAAQGNAAFIDAGACKAYAVKARVKLQEQLARETAKP"}}}}, "ARO_category": [], "ARO_name": "MSI-1", "model_type": "protein homolog model", "model_description": "Models to detect proteins conferring antibiotic resistance, which include a reference protein sequence and a curated BLASTP cut-off.", "ARO_id": "40372", "model_name": "MSI-1", "model_type_id": "40292"}}}