Model_id Action ARO_name ARO_category Changes To Summary 212 UPDATE Staphylococcus aureus parC conferring resistance to fluoroquinolone antibiotic resistant gene variant or mutant; fluoroquinolone resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1301 UPDATE Staphylococcus aureus cls conferring resistance to daptomycin antibiotic resistant gene variant or mutant; lipopeptide antibiotic resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 660 UPDATE Streptococcus pneumonia parC conferring resistance to fluoroquinolone antibiotic resistant gene variant or mutant; fluoroquinolone resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2097 UPDATE Escherichia coli 16S rRNA mutation in the rrsB gene conferring resistance to paromomycin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2096 UPDATE Escherichia coli 16S rRNA mutation in the rrsC gene conferring resistance to kasugamicin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2091 UPDATE Mycobacterium chelonae 16S rRNA mutation conferring resistance to gentamicin C antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2090 UPDATE Mycobacterium abscessus 16S rRNA mutation conferring resistance to kanamycin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2093 UPDATE Chlamydophila psittaci 16S rRNA mutation conferring resistance to spectinomycin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_sequences; model_param "UPDATED fmin with 0 UPDATED NCBI_taxonomy_cvterm_id with 40343 UPDATED NCBI_taxonomy_name with Chlamydia psittaci 6BC UPDATED NCBI_taxonomy_id with 331636 UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2092 UPDATE Enterobacter aerogenes acrR mutation resulting in antibiotic resistance chloramphenicol resistance gene; gene modulating antibiotic efflux; fluoroquinolone resistance gene; efflux pump conferring antibiotic resistance; antibiotic resistant gene variant or mutant; tetracycline resistance gene; rifampin resistance gene; beta-lactam resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2099 UPDATE Mycobacterium smegmatis 16S rRNA mutation in the rrsB gene conferring resistance to kanamycin A antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2098 UPDATE Mycobacterium smegmatis 16S rRNA mutation in the rrsB gene conferring resistance to viomycin peptide antibiotic resistance gene; antibiotic resistant gene variant or mutant; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1545 UPDATE Escherichia coli gyrA conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; fluoroquinolone resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1540 UPDATE rmtC antibiotic target modifying enzyme; aminoglycoside resistance gene; model_sequences "UPDATED fmax with 925 UPDATED strand with + UPDATED accession with KJ476816.1 UPDATED fmin with 79 UPDATED sequence with ATGAAAACCAACGATAATTATATCGAAGAAGTAACAGCCAAAGTACTCACAAGTGGTAAATACTCCACACTTTATCCACCAACTGTACGACGTGTAACTGAGAGGCTTTTCGATCGATACCCTCCCAAGCAGCTAGAGAAGGAGGTTCGCAAGAAATTGCATCAAGCATATGGTGCTTATATTGGTGGGATCGATGGGAAAAGGTTGGAGAAGAAGATTGAGAAGATAATTCATGAGATACCAAATCCAACTACGGATGAAGCAACTCGTACGGAGTGGGAAAAAGAGATCTGCCTGAAAATATTGAACTTGCACACTTCAACAAATGAGCGAACGGTGGCTTACGATGAGCTTTACCAAAAGATCTTTGAGGTAACAGGGGTTCCAACAAGTATCACCGATGCAGGTTGCGCTTTGAATCCATTTTCTTTTCCATTCTTTACGGAGGCTGGCATGCTTGGGCAATACATAGGTTTCGATCTTGATAAAGGTATGATCGAAGCGATCGAACACTCGTTGAGAACGCTTAACGCCCCAGAGGGTATTGTTGTCAAACAGGGAGATATATTATCCGATCCGTCAGGCGAGAGTGATCTTCTACTTATGTTCAAGCTATATACTCTACTCGATCGGCAGGAAGAGGCCTCTGGTTTGAAAATTCTTCAAGAGTGGAAATACAAAAATGCTGTGATCTCTTTTCCTATTAAAACTATAAGTGGGAGAGATGTTGGGATGGAAGAGAATTACACTGTTAAGTTCGAGAATGATCTTGTTGGGTCAGATCTGAGAATCATGCAAAAATTGAAATTAGGAAACGAGATGTATTTTATCGTATCGAGATTGTAA UPDATED NCBI_taxonomy_name with Pseudomonas aeruginosa UPDATED NCBI_taxonomy_id with 287 UPDATED NCBI_taxonomy_cvterm_id with 36752 UPDATED GI with AIA09786.1 UPDATED sequence with MKTNDNYIEEVTAKVLTSGKYSTLYPPTVRRVTERLFDRYPPKQLEKEVRKKLHQAYGAYIGGIDGKRLEKKIEKIIHEIPNPTTDEATRTEWEKEICLKILNLHTSTNERTVAYDELYQKIFEVTGVPTSITDAGCALNPFSFPFFTEAGMLGQYIGFDLDKGMIEAIEHSLRTLNAPEGIVVKQGDILSDPSGESDLLLMFKLYTLLDRQEEASGLKILQEWKYKNAVISFPIKTISGRDVGMEENYTVKFENDLVGSDLRIMQKLKLGNEMYFIVSRL " 1943 UPDATE Mycobacterium tuberculosis kasA mutant conferring resistance to isoniazid antibiotic resistant gene variant or mutant; isoniazid resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 29 UPDATE Escherichia coli sulfonamide resistant mutant folP antibiotic resistant gene variant or mutant; sulfonamide resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2154 UPDATE Borrelia burgdorferi 16S rRNA mutation conferring resistance to spectinomycin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_sequences; model_param "UPDATED fmin with 0 UPDATED NCBI_taxonomy_cvterm_id with 40345 UPDATED NCBI_taxonomy_name with Borrelia burgdorferi UPDATED NCBI_taxonomy_id with 139 UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2155 UPDATE Propionibacterium acnes 16S rRNA mutation conferring resistance to tetracycline antibiotic resistant gene variant or mutant; tetracycline resistance gene; model_sequences; model_param "UPDATED fmin with 0 UPDATED NCBI_taxonomy_cvterm_id with 40344 UPDATED NCBI_taxonomy_name with Propionibacterium acnes UPDATED NCBI_taxonomy_id with 1747 UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2157 UPDATE Escherichia coli 16S rRNA mutation in the rrsB gene conferring resistance to gentamicin C antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2150 UPDATE efflux pump conferring antibiotic resistance model_description "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. " 2152 UPDATE Neisseria meningitidis 16S rRNA mutation conferring resistance to spectinomycin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2158 UPDATE Escherichia coli EF-Tu mutants conferring resistance to Pulvomycin antibiotic resistant gene variant or mutant; elfamycin resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1671 UPDATE Salmonella serovars soxS mutants chloramphenicol resistance gene; gene modulating antibiotic efflux; gene modulating permeability to antibiotic; fluoroquinolone resistance gene; efflux pump conferring antibiotic resistance; antibiotic resistant gene variant or mutant; tetracycline resistance gene; rifampin resistance gene; beta-lactam resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2073 UPDATE Escherichia coli 16S rRNA mutation in the rrsB gene conferring resistance to G418 antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1558 UPDATE Bacillus subtilis mprF mutations conferring resistance to daptomycin antibiotic resistant gene variant or mutant; lipopeptide antibiotic resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1822 UPDATE Staphylococcus aureus gyrB conferring resistance to aminocoumarin aminocoumarin resistance gene; antibiotic resistant gene variant or mutant; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2147 UPDATE Escherichia coli EF-Tu mutants conferring resistance to Enacyloxin IIa antibiotic resistant gene variant or mutant; elfamycin resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2146 UPDATE Escherichia coli 16S rRNA mutation in the rrnB gene conferring resistance to streptomycin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2145 UPDATE Escherichia coli 16S rRNA mutation in the rrsB gene conferring resistance to tetracycline antibiotic resistant gene variant or mutant; tetracycline resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2144 UPDATE Mycobacterium bovis embB mutations conferring resistance to ethambutol ethambutol resistance gene; antibiotic resistant gene variant or mutant; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2143 UPDATE Borrelia burgdorferi 16S rRNA mutation conferring resistance to gentamicin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_sequences; model_param "UPDATED fmin with 0 UPDATED NCBI_taxonomy_cvterm_id with 40345 UPDATED NCBI_taxonomy_name with Borrelia burgdorferi UPDATED NCBI_taxonomy_id with 139 UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2142 UPDATE Mycobacterium smegmatis 16S rRNA mutation in the rrsA gene conferring resistance to viomycin peptide antibiotic resistance gene; antibiotic resistant gene variant or mutant; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2141 UPDATE Mycobacterium smegmatis 16S rRNA mutation in the rrsB gene conferring resistance to neomycin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2140 UPDATE Escherichia coli 16S rRNA mutation in the rrsB gene conferring resistance to streptomycin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 821 UPDATE Mycobacterium tuberculosis embB mutants conferring resistance to rifampicin rifampin resistance gene; antibiotic resistant gene variant or mutant; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2149 UPDATE Mycobacterium smegmatis 16S rRNA mutation in the rrsA gene conferring resistance to hygromycin B antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2148 UPDATE Ureaplasma urealyticum gyrB conferring resistance to fluoroquinolone antibiotic resistant gene variant or mutant; fluoroquinolone resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1323 UPDATE Salmonella serovars parE conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; fluoroquinolone resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1320 UPDATE Klebsiella mutant PhoP conferring antibiotic resistance to colistin gene modulating antibiotic efflux; gene altering cell wall charge conferring antibiotic resistance; macrolide resistance gene; efflux pump conferring antibiotic resistance; antibiotic resistant gene variant or mutant; polymyxin resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 597 UPDATE Klebsiella pneumoniae ramR mutants chloramphenicol resistance gene; gene modulating antibiotic efflux; fluoroquinolone resistance gene; efflux pump conferring antibiotic resistance; antibiotic resistant gene variant or mutant; tetracycline resistance gene; rifampin resistance gene; beta-lactam resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 196 UPDATE Mycobacterium tuberculosis embB mutations conferring resistance to ethambutol ethambutol resistance gene; antibiotic resistant gene variant or mutant; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 984 UPDATE Bartonella bacilliformis gyrA conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; fluoroquinolone resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1088 UPDATE Staphylococcus aureus rpoB mutants conferring resistance to daptomycin antibiotic resistant gene variant or mutant; lipopeptide antibiotic resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 117 UPDATE elfamycin resistant EF-Tu antibiotic resistant gene variant or mutant; elfamycin resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 111 UPDATE Escherichia coli gyrB conferring resistance to aminocoumarin aminocoumarin resistance gene; antibiotic resistant gene variant or mutant; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 276 UPDATE tetR efflux pump conferring antibiotic resistance; antibiotic resistant gene variant or mutant; tetracycline resistance gene; gene modulating antibiotic efflux; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2068 UPDATE Escherichia coli 16S rRNA mutation conferring resistance to edeine peptide antibiotic resistance gene; antibiotic resistant gene variant or mutant; polyamine resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 794 UPDATE Staphylococcus aureus rpoC conferring resistance to daptomycin antibiotic resistant gene variant or mutant; lipopeptide antibiotic resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2069 UPDATE Escherichia coli 16S rRNA mutation in the rrsB gene conferring resistance to neomycin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 535 UPDATE Morganella morganii gyrB conferring resistance to fluoroquinolone antibiotic resistant gene variant or mutant; fluoroquinolone resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 3 UPDATE Escherichia coli ompF mutants antibiotic resistant gene variant or mutant; beta-lactam resistance gene; gene modulating permeability to antibiotic; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2078 UPDATE Mycobacterium chelonae 16S rRNA mutation conferring resistance to kanamycin A antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 919 UPDATE PER-1 antibiotic inactivation enzyme; beta-lactam resistance gene; model_sequences "UPDATED fmax with 1211 UPDATED strand with - UPDATED accession with Z21957.1 UPDATED fmin with 284 UPDATED sequence with TTAATTTGGGCTTAGGGCAGAAAGCTTTTTCAATTCAAATTGATACGCAGTCTGAGCAACCTGCGCAATGATAGCTTCATTGGTTCGGCTTGACTCGGCTGAGTCTTTCACAAAAACAGCAACCAGCAAGGGCCGTCCATCAGGCAACAGAATGATACCTAAATCATTAGTGGCCGCAGTTTTTCCGGCTTTGATACCCGAAGTACCAGTTTTATGTGCGACCACAGTACCAGCTGGTAACAAACCTTTTAACCGCTCTGGTCCTGTGGTGGTTTCGACCATCCACTTCCATAACAAAGCCTGCGAGGTTTCAGACAGCTGTGTTTTTTGCTCAAACTTTTTCAGGATCTCTGCAGCACCTTTCATCGAGGTCCAGTTTTGATACTGCACCTGATCATCGGCGTGCATCTGCGCTTCATTTGCGACCACAGCGGTCTCCTTTATACCCATAGACTGGATATAGTCATGCAAAGCAGCTGGTCCACCAACCAGTTCAAATAACAAATCACAGGCCACGTTATCGCTGTGCGAGACCGAGTATTGCAGCAGTTGCTGCACTGGAACACTAAACTCGTCTCCCTGATACGCTTTCATTATCGGAGCCCAGGTATTCTGTAAAACCTTAGCCCTGTTTACGATAACGGTCTGATTTAAATCCAACTTTCCCTGATCAACCTGATGCAGTACCAACATAGCTAAATGCAATTTAAATACACTTTGCATTGGGAATTTTTCAAAAGGATTAATCAGTAAAGGTTCCAGATCGTCAGGCCCCCACACTGCAACGCCTACAGTGGCTTTTTTTCCAATGACTATGGATTCAATTTGCTCTTTTAACAGTGGGGATTGCGCTGAGGTTTCGAATGAACTAAAAGATACCATCAGTAGCGTCGAGGCAGTAACTACAGCTTTTATAATGACATTCAT UPDATED NCBI_taxonomy_name with Pseudomonas aeruginosa UPDATED NCBI_taxonomy_id with 287 UPDATED NCBI_taxonomy_cvterm_id with 36752 UPDATED GI with CAA79968.1 UPDATED sequence with MNVIIKAVVTASTLLMVSFSSFETSAQSPLLKEQIESIVIGKKATVGVAVWGPDDLEPLLINPFEKFPMQSVFKLHLAMLVLHQVDQGKLDLNQTVIVNRAKVLQNTWAPIMKAYQGDEFSVPVQQLLQYSVSHSDNVACDLLFELVGGPAALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQALLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGIKAGKTAATNDLGIILLPDGRPLLVAVFVKDSAESSRTNEAIIAQVAQTAYQFELKKLSALSPN " 366 UPDATE Mycobacterium tuberculosis iniA mutant conferring resistance to Ethambutol efflux pump conferring antibiotic resistance; antibiotic resistant gene variant or mutant; ethambutol resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 914 UPDATE ANT(6)-Ia antibiotic inactivation enzyme; aminoglycoside resistance gene; model_sequences "UPDATED fmax with 61860 UPDATED strand with - UPDATED accession with NC_023287 UPDATED fmin with 60996 UPDATED sequence with TTAAAAATAGTCATTTTCAACATATTTTTTATACATGTCCTCGGTATATCTTGTTATGTTCTTACCATACTCTGGATAATCAAACCCCAGTAGTTCTGCTACCTCTTTGGACACTTCCCTGAACAATTGGTGGCATATAAATAATGACTTCCAAATATTTTCATAGGAATCCATGCGATATGTAGATAATAATCTATTCCATAGATCTTCATCAATGTATTTGTTAATATACTTATAATTTTTCCCAACACTTAATGAAAATTCTGTCTTTATCCCAACCTTCCACGACATCATCCTAAGTAGTTCAAACCGTAGAATCTGGTTCAGATGATCGATTGCAAACAGTATCTCTTTGCGGCACAATCCTTTAATAACATAAGGTGTTACATTCCAAAATTCATTGCAGCAATCATCATACTCCCTTGCGCTTGGCTTTCTTACATGATAATCTATATCAGTCGGAACTATGTCCCTTTTAATTCTACAATCTTTATCAATTAGAACCTTTATTAATTTATCGCCCTTTAGGTAATTATCTAACTCTTCCAAGGGCAATAAGGTAAGATCAATTTTATTGTAATCATCAAATAGCATAAGATAGGAAAATCCCTTTTCTTCAGGTGGGAATAATTCCATATCCTCCGGCTTTTGCATCATTATTATATTCCCAAATTGATTAAGCCAGTCATCATTAGATATAAACGGTTCTATATCACTTACAAAATATGTAATATCATAATCCTGAAATTCATCTTTAGGTATATTAATATTTGCGCGTGACCCCTCAAGGGTCACAATTCGAATACGTTCATCCTGTTCTGCTAAAGAAAGTACTAAATCCATCATTTCTTTTTCTGATCTCAT UPDATED NCBI_taxonomy_name with Exiguobacterium sp. S3-2 UPDATED NCBI_taxonomy_id with 1389960 UPDATED NCBI_taxonomy_cvterm_id with 39580 UPDATED GI with 571046704 UPDATED sequence with MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYDITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLTLLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNVTPYVIKGLCRKEILFAIDHLNQILRFELLRMMSWKVGIKTEFSLSVGKNYKYINKYIDEDLWNRLLSTYRMDSYENIWKSLFICHQLFREVSKEVAELLGFDYPEYGKNITRYTEDMYKKYVENDYF " 1395 UPDATE Neisseria gonorrhoeae mutant porin PIB (por) with reduced permeability to antibiotic beta-lactam resistance gene; antibiotic resistant gene variant or mutant; tetracycline resistance gene; gene modulating permeability to antibiotic; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2070 UPDATE Mycobacterium tuberculosis 16S rRNA mutation conferring resistance to amikacin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2077 UPDATE Mycobacterium smegmatis 16S rRNA mutation in the rrsA gene conferring resistance to neomycin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2076 UPDATE Neisseria gonorrhoeae 16S rRNA mutation conferring resistance to spectinomycin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1405 UPDATE armA antibiotic target modifying enzyme; aminoglycoside resistance gene; model_sequences "UPDATED fmax with 774 UPDATED strand with + UPDATED accession with GU437214.1 UPDATED fmin with 0 UPDATED sequence with ATGGATAAGAATGATGTTGTTAAGAAGATACTTGAATCAAAAAAGTACGAAAACCTTGATTCAGATATTGTTGAAAAGGTTGTTTCCATTTCTGAGAAGAAATATAAATTAAAGGAAGTTGAGAATTATTCTAAAAAGAAATTGCATCAAATATGGGGGTCTTACTATTCTGCCTATCCTAATTGGGATAAATTATTAAAAAAGTACAATCAGGGGCAGTTATCAATAGAAGATTTACTAAAGATTCATTCTTCGACGAATGAAAGAGTCGCAACATTAAATGACTTTTACACTTATGTATTTGGAAATATCAAACATGTCTCATCTATTTTAGATTTTGGTTGTGGCTTCAATCCATTAGCTTTATACCAATGGAATGAAAATGAAAAAATAATATATCATGCATACGATATTGATAGAGCTGAGATAGCTTTTTTGAGTAGCATTATTGGGAAGTTAAAGACGACGATAAAGTATAGGTTTTTGAATAAAGAGAGTGATGTCTACAAAGGTACTTATGATGTAGTATTCCTTTTAAAGATGCTTCCTGTGCTAAAACAGCAAGATGTAAATATCTTGGATTTCCTACAGCTTTTTCATACTCAAAACTTTGTAATATCTTTTCCAATAAAGTCTTTATCTGGAAAGGAGAAGGGAATGGAAGAGAATTACCAGCTATGGTTTGAATCTTTTACAAAAGGTTGGATAAAAATCCTTGATTCGAAGGTTATAGGGAATGAGTTAGTATATATTACTAGTGGATTTCAGAAATAA UPDATED NCBI_taxonomy_name with Pseudomonas aeruginosa UPDATED NCBI_taxonomy_id with 287 UPDATED NCBI_taxonomy_cvterm_id with 36752 UPDATED GI with ADC55560.1 UPDATED sequence with MDKNDVVKKILESKKYENLDSDIVEKVVSISEKKYKLKEVENYSKKKLHQIWGSYYSAYPNWDKLLKKYNQGQLSIEDLLKIHSSTNERVATLNDFYTYVFGNIKHVSSILDFGCGFNPLALYQWNENEKIIYHAYDIDRAEIAFLSSIIGKLKTTIKYRFLNKESDVYKGTYDVVFLLKMLPVLKQQDVNILDFLQLFHTQNFVISFPIKSLSGKEKGMEENYQLWFESFTKGWIKILDSKVIGNELVYITSGFQK " 2074 UPDATE Salmonella enterica serovar Typhimurium 16S rRNA mutation in the rrsD gene conferring resistance to spectinomycin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1235 UPDATE AAC(6')-Ib' antibiotic inactivation enzyme; aminoglycoside resistance gene; model_sequences "UPDATED fmax with 3902 UPDATED strand with + UPDATED accession with AY660529.1 UPDATED fmin with 0 UPDATED sequence with GGCATCCAAGCAGCAAGCGCGTTACGCCGTGGGTCGATGTTTGATGTTATGGAGCAGCAACGATGTTACGCAGCAGGGCAGTCGCCCTAAAACAAAGTTAGGCATCACAAAGTACAGCATCGTGACCAACAGCAACGATTCCGTCACACTGCGCCTCATGACTGAGCATGACCTTGCGATGCTCTATGAGTGGCTAAATCGATCTCATATCGTCGAGTGGTGGGGCGGAGAAGAAGCACGCCCGACACTTGCTGACGTACAGGAACAGTACTTGCCAAGCGTTTTAGCGCAAGAGTCCGTCACTCCATACATTGCAATGCTGAATGGAGAGCCGATTGGGTATGCCCAGTCGTACGTTGCTCTTGGAAGCGGGGACGGATGGTGGGAAGAAGAAACCGATCCAGGAGTACGCGGAATAGACCAGTCACTGGCGAATGCATCACAACTGGGCAAAGGCTTGGGAACCAAGCTGGTTCGAGCTCTGGTTGAGTTGCTGTTCAATGATCCCGAGGTCACCAAGATCCAAACGGACCCGTCGCCGAGCAACTTGCGAGCGATCCGATGCTACGAGAAAGCGGGGTTTGAGAGGCAAGGTACCGTAACCACCCCAGATGGTCCAGCCGTGTACATGGTTCAAACACGCCAGGCATTCGAGCGAACACGCAGTGTTGCCTAACCCTTCCATCGAGGGGGACGTCCAAGGGCTGGCGCCCTTGGCCGCCCCTCATGTCAAACGTTAGCCACCAAGAAGGTGCCATGAAAACATTTGCCGCATATGTAATTACTGCGTGTCTTTCAAGTACGGCATTAGCTAGTTCAATTACAGAAAATACGTTTTGGAACAAAGAGTTCTCTGCCGAAGCCGTCAATGGTGTTTTCGTGCTTTGTAAAAGTAGCAGTAAATCCTGCGCTACCAATAACTTAGCTCGTGCATCAAAGGAATATCTTCCAGCATCAACATTTAAGATCCCCAACGCAATTATCGGCCTAGAAACTGGTGTCATAAAGAATGAGCATCAGATTTTCAAATGGGACGGAAAGCCAAGAGCCATGAAACAATGGGAAAGAGACTTGAGCTTAAGAGGGGCAATACAAGTTTCAGCGGTTCCCGTATTTCAACAAATCGCCAGAGAAGTTGGCGAAGTAAGAATGCAGAAATATCTTAAAAAATTTTCATATGGTAACCAGAATATCAGTGGTGGCATTGACAAATTCTGGTTGGAGGGTCAGCTTAGAATTTCCGCAGTTAATCAAGTGGAGTTTCTAGAGTCTCTATTTTTAAATAAATTGTCAGCATCAAAAGAAAATCAGCTAATAGTAAAAGAGGCTTTGGTAACGGAGGCTGCGCCTGAATATCTTGTGCATTCAAAAACTGGTTTTTCTGGTGTGGGAACTGAGTCAAATCCTGGTGTCGCATGGTGGGTTGGTTGGGTTGAGAAGGGAGCAGAGGTTTACTTTTTCGCCTTTAACATGGATATAGACAACGAAAATAAGTTGCCGCTAAGAAAATCCATTCCCACCAAAATCATGGCAAGTGAGGGCATCATTGGTGGCTAACAATTCGCTGCAGGCGCGACGGCCCTGACGGGTCCGCGGCCTGAGCTCAAACGTTAGACATCATGAGTGAAAAAGTGCCCGCCGAGATTTCGGTGCAACTATCACAAGCACTCAACGTCATCGGGCGCCACTTGGAGTCGACGTTGCTGGCCGTGCATTTGTACGGCTCCGCACTGGATGGCGGATTGAAACCGTACAGTGATATTGATTTGCTGGTGGCTGTAGCTGCACCGCTCAATGATGCCGTGCGGCAAGCCCTGCTCGTCGATCTCTTGGAGGTTTCAGCTTCCCCTGGCCAAAACAAGGCACTCCGCGCCTTGGAAGTGACCATCGTCGTGCACAGTGACATCGTACCTTGGCGTTATCCGGCCAGGCGGGAACTGCAGTTCGGAGAGTGGCAGCGCAAAGACATCCTTGCGGGCATCTTCGAGCCCGCCACAACCGATTCTGACTTGGCGATTCTGCTAACAAAGGCAAAGCAACATAGCATCGTCTTGGCAGGTTCAGCAGCGAAGGATCTCTTCAGCTCAGTCCCAGAAAGCGATCTATTCAAGGCACTGGCCGATACTCTGAAGCTATGGAACTCGCCGCCAGATTGGGCGGGCGATGAGCGGAATGTAGTGCTTACTTTGTCTCGTATCTGGTACACCGCAGCAACCGGCAAGATCGCGCCAAAGGATGTTGCTGCCACTTGGGCAATGGCACGCTTGCCAGCTCAACATCAGCCCATCCTGTTGAATGCCAAGCGGGCTTATCTTGGGCAAGAAGAAGATTATTTGCCCGCTCGTGCGGATCAGGTGGCGGCGCTCATTAAATTCGTGAAGTATGAAGCAGTTAAACTGCTTGGTGCCAGCCAATGATGTCTAACAATTCATATATGGACTCTCCCCACAAGCAGTGAGGAAAGCTTTTTTCGATCCTGTCGTCAGCGCGGTTGCATTCGTATATCCGGCCTTGTCGTGGGCAGTGCCCTGGCCATGCTGTAGTTCGCGCAGCGGGGGCCAAGCGTTCAAACGATCCCGAAGATCATGATTGTTATCGGCCTTGTACCGCTGCAGGACTCGCCTGTTCCGACAGTCTCGCTTCTCACCACAACCGCAAGAAATAACGCGTCTTCCTGATTACCCCGCCGTCAGGCGGGCCTTGCACTCTGCCAGTCGCCACTGAAGCGGCGTTCGTGGCACCACACCGCCCAGCAGATCCTCACCAGTTTGTTCGCCAGGGCCACGGCAGCCTTGTTGTGGCCGATGCGTTCGGCCGTCTGCAGGGCCCAGCGCTGCAGCTGGGTCAGGCGTTGCGGCGTTCGTGCCTGGCAGCGCTTGGCGGCCAGCAACGCCGCGCGGGCGCCGTGGATCAGCAGCGTTCGCACGTAAACATTGCCCTTGCAGCTGATGCGGCCGAGCTTGCGGCGCTCGCCGCTGCTGTATTCGTTGGGCGTCATGCCCAGCCAGGCGCTCAGATGCCGGCCGCTGGCAAAGCGTTCGGGTTTGCCCACAGCGGTTTTCAGGGCGCTGGCGGTGAGCAGGCCGATGCCGCTGACTTCATCGAGCTTGTGCACGATGTCGTCGTCGGCATGCCAGCGCGCCAGTTGGTCTTCGCACTCACGCATCGACTGTTCGTAGAGGTTGATTTCAGCCAGTACCACTTGCAGGACACCACGCAGAGCCTGCACCTCGGGCTGCTCGATCAACGCGCAGGCCTGGCGCAGAAACGCCTGGGTGCCGTTGGGCGCGGCCACGCCCATCTCGCGCAGGATGCCGCGCAACAGGTTGATGCGCTGGACCCGGGTCTTCTTCCAGGCCTCGCGCATTTTGTGCAGCTGCTGCACCTGTTGCTGCTGCACGCTTTTGACCGGCACCGGACGGATACCCTCGCAACGAGCCGCCTCCAGGATCGCATCGCAGTCGTTGCGATCGGTCTTACTGCGCCGGCGATAGGCCCGCACGTAGCGCGGATGCAGCAGCACCACGCGATGCCCCGCCGCCTGCATCAACCGGCCCCAGTGGTGAGCCGTGCCGCAGGCCTCCATCACCCACTCGACAGGCGCCGGCTGCTCCTGTACATAACGCCAGAACGCCTCCGGATCGAGCCGCCTGCGACGATCCACCCGACCGACATGGATACTTTCGGCAACTTGGTAAACGGACTTGGCCAAATCAATTGCAATGCGTTTCATCTTCACTCTCCCGGCAAACAGACACCTCGTGTCTTATAGAAGAAACGCGGTGCGGGGAGAGTCCATTACAGCCTTCAAGCCGACGCCGCTTCGCGGCGCGGCTTAATTCAAGCGTTAGATGCACTAAGCACATAATTGCTCACAGCCAAACTATCAGGTCAAGTCTGCT UPDATED NCBI_taxonomy_name with Pseudomonas aeruginosa UPDATED NCBI_taxonomy_id with 287 UPDATED NCBI_taxonomy_cvterm_id with 36752 UPDATED GI with AAT74613.1 UPDATED sequence with MTNSNDSVTLRLMTEHDLAMLYEWLNRSHIVEWWGGEEARPTLADVQEQYLPSVLAQESVTPYIAMLNGEPIGYAQSYVALGSGDGWWEEETDPGVRGIDQSLANASQLGKGLGTKLVRALVELLFNDPEVTKIQTDPSPSNLRAIRCYEKAGFERQGTVTTPDGPAVYMVQTRQAFERTRSVA " 1237 UPDATE Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin rifampin resistance gene; antibiotic resistant gene variant or mutant; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1339 UPDATE Mycobacterium tuberculosis embR mutant conferring resistance to ethambutol ethambutol resistance gene; antibiotic resistant gene variant or mutant; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1135 UPDATE Staphylococcus aureus parE conferring resistance to aminocoumarin aminocoumarin resistance gene; antibiotic resistant gene variant or mutant; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1935 UPDATE Mycobacterium tuberculosis gyrA conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; fluoroquinolone resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 100 UPDATE mycobacterium tuberculosis ethA mutant conferring resistance to ethionamide antibiotic resistant gene variant or mutant; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1849 UPDATE Mycobacterium tuberculosis tlyA mutations conferring resistance to aminoglycosides antibiotic target modifying enzyme; antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1432 UPDATE Mycobacterium tuberculosis mutant embC conferring resistance to ethambutol ethambutol resistance gene; antibiotic resistant gene variant or mutant; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 904 UPDATE rmtB antibiotic target modifying enzyme; aminoglycoside resistance gene; model_sequences "UPDATED fmax with 252 UPDATED strand with + UPDATED accession with FJ483516.1 UPDATED fmin with 0 UPDATED sequence with TATGGAACTATTCACGATGCCCTCACCTCCATCCTGGCCTCAAAAAAATACCGCGCCCTTTGCCCGGATACCGTGCGGCGCATCCTGACTGAGGAATGGGGGCGGCATAAATCCCCCAAACAGACCGTAGAGGCTGCACGCACCCGGCTGCATGGAATTTGCGGGGCATATGTCACCCCGGAATCGCTCAAGGCTGCTGCCGCCGCGCTTTCTGCGGGCGATGTAAAAAAGGCATTGTCGCTGCATGCCTCC UPDATED NCBI_taxonomy_name with Pseudomonas aeruginosa UPDATED NCBI_taxonomy_id with 287 UPDATED NCBI_taxonomy_cvterm_id with 36752 UPDATED GI with ACL31576.1 UPDATED sequence with YGTIHDALTSILASKKYRALCPDTVRRILTEEWGRHKSPKQTVEAARTRLHGICGAYVTPESLKAAAAALSAGDVKKALSLHASTKERLAELDTLYDFIFSAETPRRVLDIACGLNPLALYERGIASVWGCDIHQGLGDVITPFAREKDWDFTFALQDVLCAPPAEAGDLALIFKLLPLLEREQAGSAMALLQSLNTPRMAVSFPTRSLGGRGKGMEANYAAWFEGGLPAEFEIEDKKTIGTELIYLIKKNG " 36 UPDATE Mycobaterium leprae gyrA conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; fluoroquinolone resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1721 UPDATE Mycobacterium leprae dapsone resistant folP mutants antibiotic resistant gene variant or mutant; sulfonamide resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2105 UPDATE Mycobacterium abscessus 16S rRNA mutation conferring resistance to neomycin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1005 UPDATE Escherichia coli soxR mutants chloramphenicol resistance gene; gene modulating antibiotic efflux; fluoroquinolone resistance gene; efflux pump conferring antibiotic resistance; antibiotic resistant gene variant or mutant; tetracycline resistance gene; rifampin resistance gene; beta-lactam resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1001 UPDATE Staphylococcus aureus mprF mutations conferring resistance to daptomycin antibiotic resistant gene variant or mutant; lipopeptide antibiotic resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 431 UPDATE Escherichia coli marR mutant resulting in antibiotic resistance chloramphenicol resistance gene; gene modulating antibiotic efflux; fluoroquinolone resistance gene; efflux pump conferring antibiotic resistance; antibiotic resistant gene variant or mutant; tetracycline resistance gene; rifampin resistance gene; beta-lactam resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1227 UPDATE aadA2 antibiotic inactivation enzyme; aminoglycoside resistance gene; model_sequences "UPDATED fmax with 5792 UPDATED strand with + UPDATED accession with AF156486 UPDATED fmin with 5012 UPDATED sequence with GTGACCATCGAAATTTCGAACCAACTATCAGAGGTGCTAAGCGTCATTGAGCGCCATCTGGAATCAACGTTGCTGGCCGTGCATTTGTACGGCTCCGCAGTGGATGGCGGCCTGAAGCCATACAGCGATATTGATTTGTTGGTTACTGTGGCCGTAAAGCTTGATGAAACGACGCGGCGAGCATTGCTCAATGACCTTATGGAGGCTTCGGCTTTCCCTGGCGAGAGCGAGACGCTCCGCGCTATAGAAGTCACCCTTGTCGTGCATGACGACATCATCCCGTGGCGTTATCCGGCTAAGCGCGAGCTGCAATTTGGAGAATGGCAGCGCAATGACATTCTTGCGGGTATCTTCGAGCCAGCCATGATCGACATTGATCTAGCTATCCTGCTTACAAAAGCAAGAGAACATAGCGTTGCCTTGGTAGGTCCGGCAGCGGAGGAATTCTTTGACCCGGTTCCTGAACAGGATCTATTCGAGGCGCTGAGGGAAACCTTGAAGCTATGGAACTCGCAGCCCGACTGGGCCGGCGATGAGCGAAATGTAGTGCTTACGTTGTCCCGCATTTGGTACAGCGCAATAACCGGCAAAATCGCGCCGAAGGATGTCGCTGCCGACTGGGCAATAAAACGCCTACCTGCCCAGTATCAGCCCGTCTTACTTGAAGCTAAGCAAGCTTATCTGGGACAAAAAGAAGATCACTTGGCCTCACGCGCAGATCACTTGGAAGAATTTATTCGCTTTGTGAAAGGCGAGATCATCAAGTCAGTTGGTAAATGA UPDATED NCBI_taxonomy_name with Klebsiella pneumoniae UPDATED NCBI_taxonomy_id with 573 UPDATED NCBI_taxonomy_cvterm_id with 35915 UPDATED GI with 6752465 UPDATED sequence with MTIEISNQLSEVLSVIERHLESTLLAVHLYGSAVDGGLKPYSDIDLLVTVAVKLDETTRRALLNDLMEASAFPGESETLRAIEVTLVVHDDIIPWRYPAKRELQFGEWQRNDILAGIFEPAMIDIDLAILLTKAREHSVALVGPAAEEFFDPVPEQDLFEALRETLKLWNSQPDWAGDERNVVLTLSRIWYSAITGKIAPKDVAADWAIKRLPAQYQPVLLEAKQAYLGQKEDHLASRADHLEEFIRFVKGEIIKSVGK " 627 UPDATE Escherichia coli rpoB mutants conferring resistance to rifampicin rifampin resistance gene; antibiotic resistant gene variant or mutant; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 624 UPDATE Mycobacterium leprae rpoB mutants conferring resistance to rifampicin rifampin resistance gene; antibiotic resistant gene variant or mutant; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 335 UPDATE Staphylococcus aureus parE conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; fluoroquinolone resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 570 UPDATE Streptococcus pyogenes sulfonamide resistant folP mutants antibiotic resistant gene variant or mutant; sulfonamide resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2191 UPDATE AAC(6')-Iaj antibiotic inactivation enzyme; aminoglycoside resistance gene; ARO_description "UPDATED ARO_description with AAC(6')-Iaj is a functional acetyltransferase that modifies the amino groups at the 6' positions of aminoglycosides and contributes to aminoglycoside resistance of P. aeruginosa " 2195 UPDATE OpmH efflux pump conferring antibiotic resistance; ARO_description "UPDATED ARO_description with OpmH is an outer membrane efflux protein required for triclosan-specific efflux pump function. " 2196 UPDATE Pseudomonas aeruginosa gyrA conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; fluoroquinolone resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2198 UPDATE Pseudomonas aeruginosa parE conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; fluoroquinolone resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 851 UPDATE Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide antibiotic resistant gene variant or mutant; pyrazinamide resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1989 UPDATE Klebsiella pneumoniae acrR mutant resulting in high level antibiotic resistance chloramphenicol resistance gene; gene modulating antibiotic efflux; fluoroquinolone resistance gene; efflux pump conferring antibiotic resistance; antibiotic resistant gene variant or mutant; tetracycline resistance gene; rifampin resistance gene; beta-lactam resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2111 UPDATE Mycobacterium chelonae 16S rRNA mutation conferring resistance to tobramycin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2113 UPDATE Escherichia coli 16S rRNA mutation in the rrsB gene conferring resistance to tobramycin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2116 UPDATE Pasteurella multocida 16S rRNA mutation conferring resistance to spectinomycin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2075 UPDATE Salmonella serovars soxR mutants chloramphenicol resistance gene; gene modulating antibiotic efflux; fluoroquinolone resistance gene; efflux pump conferring antibiotic resistance; antibiotic resistant gene variant or mutant; tetracycline resistance gene; rifampin resistance gene; beta-lactam resistance gene; model_description "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. " 756 UPDATE Enterococcus faecium liaR mutant conferring daptomycin resistance peptide antibiotic resistance gene; antibiotic resistant gene variant or mutant; lipopeptide antibiotic resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 462 UPDATE Staphylococcus aureus pgsA mutations conferring resistance to daptomycin antibiotic resistant gene variant or mutant; lipopeptide antibiotic resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2122 UPDATE Mycobacterium chelonae 16S rRNA mutation conferring resistance to neomycin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2187 UPDATE Staphylococcus aureus parE conferring resistance to aminocoumarin model_description "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. " 90 UPDATE Staphylococcus aureus rpoB mutants conferring resistance to rifampicin rifampin resistance gene; antibiotic resistant gene variant or mutant; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2189 UPDATE Ureaplasma urealyticum parC conferring resistance to fluoroquinolone model_description "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. " 2188 UPDATE Mycoplasma hominis parC conferring resistance to fluoroquinolone model_description "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. " 505 UPDATE Mycobacterium tuberculosis iniC mutant conferring resistance to ethambutol efflux pump conferring antibiotic resistance; antibiotic resistant gene variant or mutant; ethambutol resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2159 UPDATE 23S rRNA with mutation conferring antibiotic resistance antibiotic resistant gene variant or mutant; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2109 UPDATE Mycobacterium tuberculosis gyrB mutant conferring resistance to fluoroquinolone antibiotic resistant gene variant or mutant; fluoroquinolone resistance gene; model_description "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. " 2108 UPDATE Escherichia coli EF-Tu mutants conferring resistance to GE2270A antibiotic resistant gene variant or mutant; elfamycin resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1450 UPDATE Escherichia coli parC conferring resistance to fluoroquinolone antibiotic resistant gene variant or mutant; fluoroquinolone resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2128 UPDATE Mycobacterium abscessus 16S rRNA mutation conferring resistance to gentamicin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2102 UPDATE Mycobacterium smegmatis 16S rRNA mutation in the rrsB gene conferring resistance to hygromycin B antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2100 UPDATE Mycobacterium chelonae 16S rRNA mutation conferring resistance to amikacin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2106 UPDATE Mycobacterium smegmatis 16S rRNA mutation in the rrsA gene conferring resistance to kanamycin A antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1108 UPDATE Enterococcus faecium liaS mutant conferring daptomycin resistance peptide antibiotic resistance gene; antibiotic resistant gene variant or mutant; lipopeptide antibiotic resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2104 UPDATE Ureaplasma urealyticum parC conferring resistance to fluoroquinolone antibiotic resistant gene variant or mutant; fluoroquinolone resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1166 UPDATE Staphylococcus aureus gyrA conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; fluoroquinolone resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1203 UPDATE Mycobacterium tuberculosis ndh mutant conferring resistance to isoniazid antibiotic resistant gene variant or mutant; isoniazid resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1894 UPDATE Salmonella serovars ramR mutants chloramphenicol resistance gene; gene modulating antibiotic efflux; fluoroquinolone resistance gene; efflux pump conferring antibiotic resistance; antibiotic resistant gene variant or mutant; tetracycline resistance gene; rifampin resistance gene; beta-lactam resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2136 UPDATE Escherichia coli 16S rRNA mutation in the rrsB gene conferring resistance to kanamycin A antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2137 UPDATE Escherichia coli EF-Tu mutants conferring resistance to kirromycin antibiotic resistant gene variant or mutant; elfamycin resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2132 UPDATE Mycobacterium tuberculosis 16S rRNA mutation conferring resistance to kanamycin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1055 UPDATE Escherichia coli parE conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; fluoroquinolone resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2131 UPDATE Mycobacterium tuberculosis 16S rRNA mutation conferring resistance to streptomycin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1966 UPDATE lmrA lincosamide resistance gene; antibiotic resistant gene variant or mutant; gene modulating antibiotic efflux; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1192 UPDATE VEB-1 antibiotic inactivation enzyme; beta-lactam resistance gene; ARO_description; model_sequences "UPDATED ARO_description with VEB-1 is a beta-lactamase found in Escherichia coli and Pseudomonas aeruginosa. UPDATED fmax with 627 UPDATED strand with + UPDATED accession with KT283240.1 UPDATED fmin with 0 UPDATED sequence with ATGCAAAGCGTTATGAAATTTCCGATTGCTTTAGCCGTTTTGTCTGAGATAGATAAAGGGAATCTTTCTTTTGAACAAAAAATAGAGATTACCCCCCAAGACCTTTTGCCTAAAACGTGGAGTCCGATTAAAGAGGAATTCCCTAATGGAACAACTTTGACGATTGAACAAATACTAAATTATACAGTATCAGAGAGCGACAATATTGGTTGTGATATTTTGCTAAAATTAATCGGAGGAACTGATTCTGTTCAAAAATTCTTGAATGCTAATCATTTCACTGATATTTCAATCAAAGCAAACGAAGAACAAATGCACAAGGATTGGAATACCCAATATCAAAATTGGGCAACCCCAACAGCGATGAACAAACTGTTAATAAATACTTATAATAATAAGAACCAATTACTTTCTAAAAAAAGTTATGATTTTTTTTGGAAAATTATGAGAGAAACAACAACAGGAAGTAACCGATTAAAAGGACAATTACCAAAGAATACAATTGTTGCTCATAAAACAGGGACTTCCGGAATAAATAATGGAATTGCAGCAGCCACTAATGATGTTGGGGTAATTACTTTACCGAATGGACAATTAATTTTTATAAGCGTATTTGTTGCAGAGTCC UPDATED NCBI_taxonomy_name with Pseudomonas aeruginosa UPDATED NCBI_taxonomy_id with 287 UPDATED NCBI_taxonomy_cvterm_id with 36752 UPDATED GI with ALC76810.1 UPDATED sequence with MQSVMKFPIALAVLSEIDKGNLSFEQKIEITPQDLLPKTWSPIKEEFPNGTTLTIEQILNYTVSESDNIGCDILLKLIGGTDSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLINTYNNKNQLLSKKSYDFFWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGINNGIAAATNDVGVITLPNGQLIFISVFVAES " 2066 UPDATE Escherichia coli soxS mutant chloramphenicol resistance gene; gene modulating antibiotic efflux; gene modulating permeability to antibiotic; fluoroquinolone resistance gene; efflux pump conferring antibiotic resistance; antibiotic resistant gene variant or mutant; tetracycline resistance gene; rifampin resistance gene; beta-lactam resistance gene; model_description "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. " 1197 UPDATE Mycobacterium tuberculosis rpsL mutations conferring resistance to Streptomycin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1696 UPDATE Salmonella serovars gyrB conferring resistance to fluoroquinolone antibiotic resistant gene variant or mutant; fluoroquinolone resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1441 UPDATE Enterobacter aerogenes omp36 mutants antibiotic resistant gene variant or mutant; beta-lactam resistance gene; gene modulating permeability to antibiotic; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1176 UPDATE Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid antibiotic resistant gene variant or mutant; isoniazid resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1175 UPDATE Enterococcus faecium cls conferring resistance to daptomycin antibiotic resistant gene variant or mutant; lipopeptide antibiotic resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1360 UPDATE Bartonella bacilliformis gyrB conferring resistance to aminocoumarin aminocoumarin resistance gene; antibiotic resistant gene variant or mutant; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1710 UPDATE Mycobacterium leprae gyrB conferring resistance to fluoroquinolone antibiotic resistant gene variant or mutant; fluoroquinolone resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 489 UPDATE Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin antibiotic target modifying enzyme; antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1354 UPDATE Mycobacterium tuberculosis embA mutant conferring resistance to ethambutol ethambutol resistance gene; antibiotic resistant gene variant or mutant; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2133 UPDATE Mycobacterium tuberculosis 16S rRNA mutation conferring resistance to viomycin peptide antibiotic resistance gene; antibiotic resistant gene variant or mutant; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2088 UPDATE Mycobacterium smegmatis 16S rRNA mutation in the rrsB gene conferring resistance to streptomycin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " _timestamp N/A N/A N/A N/A NEW: 2016-03-23T17:46:56+00:00 , OLD: 2015-12-14T16:04:28+00:00 2124 UPDATE Clostridium difficile EF-Tu mutants conferring resistance to elfamycin antibiotic resistant gene variant or mutant; elfamycin resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2127 UPDATE Borrelia burgdorferi 16S rRNA mutation conferring resistance to kanamycin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_sequences; model_param "UPDATED fmin with 0 UPDATED NCBI_taxonomy_cvterm_id with 40345 UPDATED NCBI_taxonomy_name with Borrelia burgdorferi UPDATED NCBI_taxonomy_id with 139 UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2126 UPDATE Mycobacterium abscessus 16S rRNA mutation conferring resistance to tobramycin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2129 UPDATE Escherichia coli 16S rRNA mutation in the rrsB gene conferring resistance to spectinomycin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2083 UPDATE Mycoplasma hominis parC conferring resistance to fluoroquinolone antibiotic resistant gene variant or mutant; fluoroquinolone resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2080 UPDATE Escherichia coli 16S rRNA mutation in the rrsH gene conferring resistance to spectinomycin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2086 UPDATE Escherichia coli 16S rRNA mutation in the rrnB gene conferring resistance to tetracycline antibiotic resistant gene variant or mutant; tetracycline resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2084 UPDATE Mycobacterium abscessus 16S rRNA mutation conferring resistance to amikacin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2085 UPDATE Escherichia coli 16S rRNA mutation in the rrnB gene conferring resistance to spectinomycin antibiotic resistant gene variant or mutant; aminoglycoside resistance gene; model_param "UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1474 UPDATE mexR chloramphenicol resistance gene; gene modulating antibiotic efflux; aminocoumarin resistance gene; macrolide resistance gene; fluoroquinolone resistance gene; efflux pump conferring antibiotic resistance; antibiotic resistant gene variant or mutant; tetracycline resistance gene; polymyxin resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 516 UPDATE PmrC polymyxin resistance gene; gene altering cell wall charge conferring antibiotic resistance; model_param "UPDATED param_value with 1e-150 " 953 UPDATE Enterococcus faecium liaF mutant conferring daptomycin resistance peptide antibiotic resistance gene; antibiotic resistant gene variant or mutant; lipopeptide antibiotic resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 1574 UPDATE Mycobacterium tuberculosis inhA mutations conferring resistance to isoniazid antibiotic resistant gene variant or mutant; isoniazid resistance gene; model_description; model_param "UPDATED model_description with A model to detect proteins that confer elevated resistance to antibiotic(s) relative to wild type. These models include reference sequences (which may or may not be a wild type sequence), a curated BLASTP cut-off, and mapped resistance variants. UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). " 2199 DELETE oprD N/A N/A 2232 ADD ESP-1 N/A N/A 2204 ADD AAC(6')-IId antibiotic inactivation enzyme; aminoglycoside resistance gene; N/A N/A 2205 ADD mexJ efflux pump conferring antibiotic resistance; tetracycline resistance gene; N/A N/A 2206 ADD mexK efflux pump conferring antibiotic resistance; tetracycline resistance gene; N/A N/A 2207 ADD mexV efflux pump conferring antibiotic resistance; chloramphenicol resistance gene; tetracycline resistance gene; fluoroquinolone resistance gene; N/A N/A 2208 ADD mexW efflux pump conferring antibiotic resistance; chloramphenicol resistance gene; tetracycline resistance gene; fluoroquinolone resistance gene; N/A N/A 2227 ADD VCC-1 N/A N/A 2224 ADD oprD N/A N/A 2222 ADD VEB-1b N/A N/A 2223 ADD mexZ N/A N/A 2220 ADD soxR chloramphenicol resistance gene; gene modulating antibiotic efflux; fluoroquinolone resistance gene; efflux pump conferring antibiotic resistance; antibiotic resistant gene variant or mutant; tetracycline resistance gene; rifampin resistance gene; beta-lactam resistance gene; N/A N/A 2221 ADD VEB-1a N/A N/A 2239 ADD ampC N/A N/A 2238 ADD vanXY glycopeptide resistance gene; gene conferring antibiotic resistance via molecular bypass; N/A N/A 2216 ADD mexM N/A N/A 2213 ADD opmE N/A N/A 2212 ADD mexQ N/A N/A 2211 ADD mexP N/A N/A 2217 ADD mexN N/A N/A 2228 ADD PEDO-1 antibiotic inactivation enzyme; beta-lactam resistance gene; N/A N/A 2215 ADD Pseudomonas aeruginosa gyrA and parC conferring resistance to fluoroquinolone N/A N/A 2231 ADD CPS-1 N/A N/A 2230 ADD PEDO-3 N/A N/A 2219 ADD mexL N/A N/A 2229 ADD PEDO-2 N/A N/A 2235 ADD SPG-1 N/A N/A 2234 ADD MSI-OXA N/A N/A 2237 ADD vanW glycopeptide resistance gene; gene conferring antibiotic resistance via molecular bypass; N/A N/A 2236 ADD vanT glycopeptide resistance gene; gene conferring antibiotic resistance via molecular bypass; N/A N/A 2233 ADD MSI-1 N/A N/A