Model_id Action ARO_name ARO_category Changes To Summary 344 UPDATE SHV-188 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 346 UPDATE QnrB23 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 347 UPDATE SFH-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 340 UPDATE CMY-51 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 341 UPDATE IMP-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 343 UPDATE OXA-31 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 348 UPDATE OXY-3-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 349 UPDATE vanL determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 512 UPDATE CTX-M-82 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2317 UPDATE mgrB efflux pump complex or subunit conferring antibiotic resistance; determinant of polymyxin resistance; gene conferring resistance via absence; protein(s) and two-component regulatory system modulating antibiotic efflux; gene altering cell wall charge; ARO_category "UPDATED category_aro_name with determinant of polymyxin resistance " 2310 UPDATE Streptomyces cinnamoneus EF-Tu mutants conferring resistance to elfamycin gene involved in self-resistance to antibiotic; antibiotic resistant gene variant or mutant; determinant of elfamycin resistance; ARO_category "UPDATED category_aro_name with determinant of elfamycin resistance " 298 UPDATE vanYG1 determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 299 UPDATE CepS beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 296 UPDATE VIM-23 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 297 UPDATE CMY-98 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 294 UPDATE CfxA4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 295 UPDATE OXA-145 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 292 UPDATE TEM-17 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 293 UPDATE SHV-180 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 290 UPDATE vatD antibiotic inactivation enzyme; determinant of streptogramin resistance; ARO_category "UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 291 UPDATE APH(3')-Ia antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 270 UPDATE LEN-20 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 271 UPDATE CMY-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 272 UPDATE QnrB36 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 273 UPDATE VEB-7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 274 UPDATE OXA-174 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 275 UPDATE OKP-B-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 277 UPDATE TEM-91 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 278 UPDATE imiS antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 279 UPDATE CTX-M-107 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 642 UPDATE aadA25 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2260 UPDATE vatF antibiotic inactivation enzyme; determinant of streptogramin resistance; ARO_category "UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 2261 UPDATE lnuE determinant of lincosamide resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. " 2267 UPDATE Escherichia coli nfsA mutations conferring resistance to nitrofurantoin determinant of nitrofuratoin resistance; antibiotic resistant gene variant or mutant; ARO_category; model_name; model_param "UPDATED category_aro_name with determinant of nitrofuratoin resistance UPDATED model_name with Escherichia coli nfsA mutations conferring resistance to nitrofurantoin UPDATED param_value with 1e-100 UPDATED param_type_id with 36302 UPDATED param_type with BLASTP e-value UPDATED param_description with A curated expectation value (e-value) for assignment of an Antibiotic Resistance Ontology term based on a BLASTP hit to a CARD reference sequence. " 2445 UPDATE erm(44) antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 108 UPDATE PDC-8 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 109 UPDATE ErmE antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 102 UPDATE TLA-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 103 UPDATE SHV-12 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 100 UPDATE Mycobacterium tuberculosis ethA with mutation conferring resistance to ethionamide determinant of ethionamide resistance; antibiotic resistant gene variant or mutant; ARO_category; model_name; model_param "UPDATED category_aro_name with determinant of ethionamide resistance UPDATED category_aro_cvterm_id with 41151 UPDATED category_aro_accession with 3004071 UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to the second-line anti-tubercular agent, ethionamide. UPDATED model_name with Mycobacterium tuberculosis ethA with mutation conferring resistance to ethionamide UPDATED param_description with A parameter to describe the mapped insertion or deletion. For an insertion: insert the location and genetic sequence of the insertion. For a deletion: insert the location of the deletion. For nucleotide space: insertion: [nt][position]+[number of nucleotides]:[nucleotides] eg. nt312+1:G. For protein space: insertion: +[amino acids][start position:end position] eg. +S3:12. If both are known, a ""/"" may be used to separate the protein and nucleotide notation eg. nt312+3:AGC/+S312. " 101 UPDATE TEM-109 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 106 UPDATE catB9 determinant of phenicol resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of phenicol resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to phenicol (chloramphenicol) antibiotics. These include chloramphenicol acetyltransferase (CAT) enzymes, which are found in a large number of species. " 107 UPDATE TEM-43 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 104 UPDATE OXA-61 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 105 UPDATE CARB-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2046 UPDATE tet(33) efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with tet(33) " 2047 UPDATE OXA-322 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2044 UPDATE QnrB31 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 2045 UPDATE OXY-2-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2042 UPDATE IND-8 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2043 UPDATE aadA8 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2040 UPDATE TEM-60 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2041 UPDATE OXA-424 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2048 UPDATE OXA-57 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2049 UPDATE QnrB72 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1213 UPDATE nalD efflux pump complex or subunit conferring antibiotic resistance; protein(s) and two-component regulatory system modulating antibiotic efflux; model_type; model_description; model_param; model_type_id "UPDATED model_type with presence and absence of protein variant model UPDATED model_description with This model detects the presence and absence of mutations in protein space. This model reflects how certain proteins are functional with and without mutations. For example, efflux pump subunits and regulators are functional with mutations and without mutations. Without mutations, efflux pump subunits and regulators are usually expressed at a low level. When an efflux pump subunit has a mutation, it can cause the drug resistance profile of the efflux pump to change. When an efflux pump regulator has a mutation, it can cause the overexpression of the efflux pump it is responsible for regulating, leading to resistance to specific drugs. Thus, the goal is to be able to detect the presence and absence of mutations in efflux pump subunits and regulators to identify a functional efflux pump system, as well as, a mutated and functional efflux pump system. UPDATED param_description with A parameter to describe the mapped insertion or deletion. For an insertion: insert the location and genetic sequence of the insertion. For a deletion: insert the location of the deletion. For nucleotide space: insertion: [nt][position]+[number of nucleotides]:[nucleotides] eg. nt312+1:G. For protein space: insertion: +[amino acids][start position:end position] eg. +S3:12. If both are known, a ""/"" may be used to separate the protein and nucleotide notation eg. nt312+3:AGC/+S312. UPDATED model_type_id with 41091 " 99 UPDATE QnrB38 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 98 UPDATE CMY-48 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 90 UPDATE Staphylococcus aureus rpoB mutants conferring resistance to rifampicin determinant of rifamycin resistance; antibiotic resistant gene variant or mutant; ARO_category "UPDATED category_aro_name with determinant of rifamycin resistance UPDATED category_aro_description with Enzymes, other proteins, or other gene products shown clinically to confer resistance to rifamycin (rifampin) antibiotics. " 93 UPDATE SHV-105 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 92 UPDATE CTX-M-42 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 95 UPDATE CMY-56 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 94 UPDATE CMY-79 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 97 UPDATE vanXYC determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 96 UPDATE OXA-426 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1623 UPDATE GIM-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1990 UPDATE CMY-82 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1993 UPDATE QnrB74 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1620 UPDATE CTX-M-156 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1627 UPDATE CTX-M-95 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1994 UPDATE gimA antibiotic inactivation enzyme; determinant of macrolide resistance; ARO_category; model_name "UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED model_name with gimA " 1625 UPDATE OXA-179 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1996 UPDATE vanXM determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1999 UPDATE TEM-215 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1998 UPDATE CTX-M-83 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1628 UPDATE SHV-154 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 559 UPDATE vanXYE determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 555 UPDATE OXA-133 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 554 UPDATE OXA-163 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 557 UPDATE SHV-9 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 556 UPDATE vanYB determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 551 UPDATE CTX-M-117 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 550 UPDATE CMY-71 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 553 UPDATE VIM-35 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 552 UPDATE QnrB28 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1199 UPDATE SHV-168 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1190 UPDATE OXA-354 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1193 UPDATE ErmH antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 1192 UPDATE VEB-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1195 UPDATE SHV-55 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1194 UPDATE OXA-16 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1197 UPDATE Mycobacterium tuberculosis rpsL mutations conferring resistance to Streptomycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1196 UPDATE OXA-71 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1759 UPDATE vanF determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1758 UPDATE OXA-326 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1756 UPDATE CMY-93 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1755 UPDATE CTX-M-23 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1754 UPDATE vanO determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1753 UPDATE SHV-148 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1751 UPDATE Erm(33) antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 1750 UPDATE OXA-254 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1177 UPDATE KPC-12 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1176 UPDATE Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid antibiotic resistant gene variant or mutant; determinant of isoniazid resistance; ARO_category; model_param "UPDATED category_aro_name with determinant of isoniazid resistance UPDATED param_description with A parameter to describe the mapped insertion or deletion. For an insertion: insert the location and genetic sequence of the insertion. For a deletion: insert the location of the deletion. For nucleotide space: insertion: [nt][position]+[number of nucleotides]:[nucleotides] eg. nt312+1:G. For protein space: insertion: +[amino acids][start position:end position] eg. +S3:12. If both are known, a ""/"" may be used to separate the protein and nucleotide notation eg. nt312+3:AGC/+S312. " 1175 UPDATE Enterococcus faecium cls conferring resistance to daptomycin antibiotic resistant gene variant or mutant; determinant of resistance to lipopeptide antibiotics; ARO_category; model_param "UPDATED category_aro_name with determinant of resistance to lipopeptide antibiotics UPDATED param_description with A parameter to describe the mapped insertion or deletion. For an insertion: insert the location and genetic sequence of the insertion. For a deletion: insert the location of the deletion. For nucleotide space: insertion: [nt][position]+[number of nucleotides]:[nucleotides] eg. nt312+1:G. For protein space: insertion: +[amino acids][start position:end position] eg. +S3:12. If both are known, a ""/"" may be used to separate the protein and nucleotide notation eg. nt312+3:AGC/+S312. " 1174 UPDATE QnrB22 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1173 UPDATE TEM-54 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1172 UPDATE OXA-194 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1171 UPDATE tet44 antibiotic target protection protein; determinant of tetracycline resistance; ARO_category "UPDATED category_aro_name with determinant of tetracycline resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to tetracycline antibiotics or tetracycline-like derivatives. " 1170 UPDATE CMY-46 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1179 UPDATE IMP-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1178 UPDATE CMY-81 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 511 UPDATE dfrA3 antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 510 UPDATE CTX-M-9 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1005 UPDATE Escherichia coli soxR mutants efflux pump complex or subunit conferring antibiotic resistance; antibiotic resistant gene variant or mutant; protein(s) and two-component regulatory system modulating antibiotic efflux; model_param; ARO_name; model_name "UPDATED 7540 with nt1130-2 UPDATED param_description with A parameter to describe the mapped insertion or deletion. For an insertion: insert the location and genetic sequence of the insertion. For a deletion: insert the location of the deletion. For nucleotide space: insertion: [nt][position]+[number of nucleotides]:[nucleotides] eg. nt312+1:G. For protein space: insertion: +[amino acids][start position:end position] eg. +S3:12. If both are known, a ""/"" may be used to separate the protein and nucleotide notation eg. nt312+3:AGC/+S312. UPDATED 7541 with L148fs UPDATED param_type_id with 40494 UPDATED param_type with frameshift UPDATED param_description with Insertion or deletion causing a frameshift mutation. These may contain data on the new STOP codon location if reported in the literature. For example, the notation for a frameshift after K136 creating a new STOP codon at P167 is: K136fs;P167STOP. If new STOP is unknown, K136fs is sufficient. UPDATED ARO_name with Escherichia coli soxR with mutation conferring antibiotic resistance UPDATED model_name with Escherichia coli soxR with mutation conferring antibiotic resistance " 1285 UPDATE SAT-1 determinant of resistance to nucleoside antibiotics; antibiotic inactivation enzyme; ARO_category; model_name "UPDATED category_aro_name with determinant of resistance to nucleoside antibiotics UPDATED model_name with SAT-1 " 1284 UPDATE IND-15 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1287 UPDATE CTX-M-110 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1286 UPDATE SHV-34 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1281 UPDATE OXA-110 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1280 UPDATE QnrB12 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1283 UPDATE KPC-6 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1282 UPDATE SIM-1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1003 UPDATE OXA-18 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 879 UPDATE TEM-185 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1289 UPDATE OKP-B-7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1288 UPDATE OXA-82 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 514 UPDATE LEN-10 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1579 UPDATE QnrB9 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1578 UPDATE SHV-123 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 689 UPDATE CTX-M-123 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 688 UPDATE MOX-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 685 UPDATE OXA-239 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 684 UPDATE SHV-37 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 687 UPDATE APH(3')-Vc antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 686 UPDATE OXA-162 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 681 UPDATE TEM-120 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 680 UPDATE CMY-54 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 683 UPDATE CMY-75 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 682 UPDATE QnrS4 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1227 UPDATE aadA2 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 459 UPDATE CTX-M-94 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1240 UPDATE Bacillus Cluster A intrinsic mph antibiotic inactivation enzyme; determinant of macrolide resistance; ARO_category; model_name "UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED model_name with Bacillus Cluster A intrinsic mph " 621 UPDATE ErmF antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 1224 UPDATE Erm(30) antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 627 UPDATE Escherichia coli rpoB mutants conferring resistance to rifampicin determinant of rifamycin resistance; antibiotic resistant gene variant or mutant; ARO_category "UPDATED category_aro_name with determinant of rifamycin resistance UPDATED category_aro_description with Enzymes, other proteins, or other gene products shown clinically to confer resistance to rifamycin (rifampin) antibiotics. " 1222 UPDATE FosA antibiotic inactivation enzyme; determinant of fosfomycin resistance; ARO_category "UPDATED category_aro_name with determinant of fosfomycin resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fosfomycin antibiotics. " 1221 UPDATE OXA-231 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1243 UPDATE mphA determinant of macrolide resistance; antibiotic inactivation enzyme; model_sequences; ARO_category "UPDATED fmax with 2531 UPDATED strand with - UPDATED accession with D16251.1 UPDATED fmin with 1625 UPDATED sequence with TCATTCCGCTGCGGCGAGCTGCGCCTTCGCCGCAGCGAGGTACTCTTCGTTACCCGAGTCGAGGGCGAAGAGTGCGTAGGTGACCGCCCCGAACGCAAGGCGCTCCGCGATGTGGTGGGCGAGCCGCGGCCACACCCGGCCACCGGCCGCTTCATACGTGAGGAGGAGCTTCGCGAGCCCCTCTTCACCAAAGACCATAAGGTGCGCGGCCATGTCGATGGCAGGGTCATCAACGCGGGCCTCGCTCCAGTCGATCATCCCGCTGACGCGCTCCGTGTTGTCGATGAGCACATGGCCCACGTAGAGATCGCCATGCACCACCACGGAGAAATCTGGCCACGACGAATCGTCGTCGAGCCAGCGCTGCCACCGGTGGAGGCGCTTGTCGTTCACCACGAACTCGCGTCGGACGCGGTCAACGTCGTCGGCCACCTTCTGACGGGCCTGCGTCGGTGTACGGATGAGCATCCCCGCATCCACGGCGGCGGAAATGGGGACGGCATGCAGGGCGGCGAGCGCGGTCGCGAAGCTCTCCGCGAAGACCTCCGAGTCCTGCGGCACGACCCAGTCGGGCGTGGACGAACCAGGCTGGATGACCATCGCAGTCGAGTCTTCGAGCATGGGATAGGCAACGAGCTCGGCGTTGGCCACGCGCCAGTCCGGCACCGCGAACGGCAGGCGATTCTTGAGCATTGCCAGCACCCGCGCCTCTGGTTCGACCTTCGCGCTTACCTCGGCTCGGCGCGGGATGCGCAGCACCCACCGACGTCCATCGTCGACGGTGGCGATCACGATCCTATAGTCGAGCCCAAGCTCATTGACAGTCAGCGGGCCATGGAGCTTGAGCCCATGTCGGGCTGCAAGTGCGTACAGTTGGGAGGTATCGGCGGTCGTGACTACGGTCAT UPDATED NCBI_taxonomy_name with Escherichia coli UPDATED NCBI_taxonomy_id with 562 UPDATED NCBI_taxonomy_cvterm_id with 35914 UPDATED GI with BAA03776.1 UPDATED sequence with MTVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVDDGRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTAMVIQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVADDVDRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMIDWSEARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVTYALFALDSGNEEYLAAAKAQLAAAE UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. " 1220 UPDATE OCH-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 407 UPDATE OXA-352 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1370 UPDATE AAC(6')-Ib10 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 405 UPDATE OXA-202 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1372 UPDATE ANT(2'')-Ia antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1375 UPDATE CMY-11 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1374 UPDATE blaI antibiotic resistance gene cluster, cassette, or operon; determinant of beta-lactam resistance; gene modulating beta-lactam resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1377 UPDATE CTX-M-60 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 400 UPDATE PDC-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1379 UPDATE OXA-313 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1378 UPDATE AAC(3)-IIc antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 452 UPDATE QnrVC4 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 409 UPDATE vanRL determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 408 UPDATE OXA-380 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1344 UPDATE mexH efflux pump complex or subunit conferring antibiotic resistance; ARO_name "UPDATED ARO_name with MexH " 1345 UPDATE tet(K) efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with tet(K) " 457 UPDATE OXA-93 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 379 UPDATE OXA-148 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 378 UPDATE TEM-214 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 647 UPDATE TEM-89 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 371 UPDATE SHV-8 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 370 UPDATE SHV-112 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 373 UPDATE MIR-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 374 UPDATE SHV-21 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 376 UPDATE lnuC determinant of lincosamide resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. " 1244 UPDATE OXY-5-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 393 UPDATE QnrS5 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 392 UPDATE TUS-1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 391 UPDATE VIM-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 390 UPDATE vanSG determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 397 UPDATE OXA-357 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 396 UPDATE sul3 antibiotic target replacement protein; determinant of sulfonamide resistance; ARO_category "UPDATED category_aro_name with determinant of sulfonamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to sulfonamide antibiotics. " 395 UPDATE TLE beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 394 UPDATE OXA-130 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 399 UPDATE MIR-16 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 398 UPDATE TEM-71 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2306 UPDATE Escherichia coli acrR mutants resulting in antibiotic resistance efflux pump complex or subunit conferring antibiotic resistance; antibiotic resistant gene variant or mutant; protein(s) and two-component regulatory system modulating antibiotic efflux; model_type; model_description; model_name; ARO_name; model_type_id "UPDATED model_type with presence and absence of protein variant model UPDATED model_description with This model detects the presence and absence of mutations in protein space. This model reflects how certain proteins are functional with and without mutations. For example, efflux pump subunits and regulators are functional with mutations and without mutations. Without mutations, efflux pump subunits and regulators are usually expressed at a low level. When an efflux pump subunit has a mutation, it can cause the drug resistance profile of the efflux pump to change. When an efflux pump regulator has a mutation, it can cause the overexpression of the efflux pump it is responsible for regulating, leading to resistance to specific drugs. Thus, the goal is to be able to detect the presence and absence of mutations in efflux pump subunits and regulators to identify a functional efflux pump system, as well as, a mutated and functional efflux pump system. UPDATED model_name with Escherichia coli acrR with mutation conferring multidrug antibiotic resistance UPDATED ARO_name with Escherichia coli acrR with mutation conferring multidrug antibiotic resistance UPDATED model_type_id with 41091 " 1246 UPDATE AAC(2')-Ic antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 244 UPDATE SHV-164 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 247 UPDATE TEM-158 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 246 UPDATE CTX-M-126 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 241 UPDATE ACT-30 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 240 UPDATE vanRF determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 243 UPDATE OXA-9 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 242 UPDATE SHV-152 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 249 UPDATE basS determinant of polymyxin resistance; gene altering cell wall charge; ARO_category; model_name "UPDATED category_aro_name with determinant of polymyxin resistance UPDATED model_name with basS " 248 UPDATE OKP-B-9 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2275 UPDATE desR gene involved in self-resistance to antibiotic; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_cvterm_id with 36454 UPDATED category_aro_accession with 3000315 UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. " 2274 UPDATE RlmA(II) antibiotic target modifying enzyme; gene involved in self-resistance to antibiotic; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. " 2277 UPDATE Bacillus Cluster B intrinsic mph antibiotic inactivation enzyme; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. " 2404 UPDATE Neisseria gonorrhoeae gyrA conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 2279 UPDATE Listeria monocytogenes mprF antibiotic target modifying enzyme; determinant of resistance to peptide antibiotics; ARO_category "UPDATED category_aro_name with determinant of resistance to peptide antibiotics " 2278 UPDATE Bifidobacteria intrinsic ileS conferring resistance to mupirocin determinant of mupirocin resistance; antibiotic resistant gene variant or mutant; ARO_category "UPDATED category_aro_name with determinant of mupirocin resistance " 179 UPDATE QnrA5 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 178 UPDATE vanHA determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 177 UPDATE IMP-51 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 176 UPDATE CMY-25 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 175 UPDATE CTX-M-24 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 174 UPDATE CfxA2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 173 UPDATE arr-4 determinant of rifamycin resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of rifamycin resistance UPDATED category_aro_description with Enzymes, other proteins, or other gene products shown clinically to confer resistance to rifamycin (rifampin) antibiotics. " 172 UPDATE oprN efflux pump complex or subunit conferring antibiotic resistance; model_name; ARO_name "UPDATED model_name with OprN UPDATED ARO_name with OprN " 171 UPDATE TEM-78 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 170 UPDATE IMP-19 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2051 UPDATE dfrA15 antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 2050 UPDATE OXA-331 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2053 UPDATE dfrA7 antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 2052 UPDATE APH(3'')-Ic antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2055 UPDATE LRA-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2057 UPDATE SHV-179 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 657 UPDATE SHV-142 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2059 UPDATE OKP-A-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 654 UPDATE dfrA26 antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 655 UPDATE OXA-243 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1367 UPDATE oleD determinant of macrolide resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. " 650 UPDATE aadA antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1364 UPDATE CMY-101 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1977 UPDATE AAC(6')-Ik antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1365 UPDATE AAC(6')-I30 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2405 UPDATE Neisseria gonorrhoeae parC conferring resistance to fluoroquinolone antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1973 UPDATE TEM-111 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1972 UPDATE OXA-149 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1971 UPDATE dfrB2 antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 1970 UPDATE SHV-44 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1968 UPDATE SHV-189 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1969 UPDATE tet(35) efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with tet(35) " 1618 UPDATE OXA-362 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1619 UPDATE L1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1616 UPDATE CTX-M-152 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1617 UPDATE vanE determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1614 UPDATE TEM-194 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1615 UPDATE APH(2'')-IIa antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1612 UPDATE ErmR antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 1613 UPDATE CMY-38 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1610 UPDATE OXA-74 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1611 UPDATE SME-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1363 UPDATE CARB-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1768 UPDATE CTX-M-144 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1769 UPDATE CTX-M-115 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1762 UPDATE aadA16 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1763 UPDATE NDM-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1760 UPDATE QnrB35 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1761 UPDATE OXA-351 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1766 UPDATE VIM-14 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1767 UPDATE OKP-A-16 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1764 UPDATE OXA-97 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1765 UPDATE OXA-56 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1142 UPDATE dfrA17 antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 1143 UPDATE OXA-7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1140 UPDATE CMY-86 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1141 UPDATE OXA-169 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1146 UPDATE TEM-156 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1147 UPDATE CMY-63 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1144 UPDATE VgbB antibiotic inactivation enzyme; determinant of streptogramin resistance; ARO_category "UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 1145 UPDATE CTX-M-124 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1148 UPDATE OXA-363 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1149 UPDATE AER-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 769 UPDATE KPC-11 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 692 UPDATE TEM-159 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 693 UPDATE OXA-22 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1544 UPDATE dfrE antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 691 UPDATE vanRE determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 696 UPDATE cfrA determinant of phenicol resistance; determinant of macrolide resistance; determinant of linezolid resistance; antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; ARO_category "UPDATED category_aro_name with determinant of linezolid resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to linezolid antibiotics. UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of phenicol resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to phenicol (chloramphenicol) antibiotics. These include chloramphenicol acetyltransferase (CAT) enzymes, which are found in a large number of species. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 697 UPDATE Erm(42) antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 694 UPDATE CTX-M-40 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1541 UPDATE ACT-14 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 698 UPDATE TEM-205 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 699 UPDATE QnrS9 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1548 UPDATE APH(3')-Vb antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1549 UPDATE ErmB antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 543 UPDATE TEM-106 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 541 UPDATE TEM-133 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 546 UPDATE TLA-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 547 UPDATE arr-5 determinant of rifamycin resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of rifamycin resistance UPDATED category_aro_description with Enzymes, other proteins, or other gene products shown clinically to confer resistance to rifamycin (rifampin) antibiotics. " 544 UPDATE AAC(6')-Is antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 545 UPDATE GES-22 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 548 UPDATE QnrB3 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 549 UPDATE TEM-107 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 760 UPDATE TEM-6 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 761 UPDATE GES-13 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 766 UPDATE SHV-102 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 767 UPDATE OXA-207 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 764 UPDATE FOX-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 765 UPDATE QnrB7 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 414 UPDATE OXA-377 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 415 UPDATE TEM-33 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 416 UPDATE OXA-204 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 417 UPDATE QnrB6 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 410 UPDATE AAC(3)-IIIb antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 411 UPDATE QnrB11 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 412 UPDATE OXA-117 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 413 UPDATE OXA-144 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1384 UPDATE OXA-382 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1386 UPDATE ANT(9)-Ia antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1387 UPDATE OXA-99 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1380 UPDATE TEM-193 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 419 UPDATE SLB-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1382 UPDATE rmtG antibiotic target modifying enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1383 UPDATE IMI-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 368 UPDATE CARB-14 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 369 UPDATE SHV-15 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 366 UPDATE Mycobacterium tuberculosis iniA mutant conferring resistance to Ethambutol efflux pump complex or subunit conferring antibiotic resistance; antibiotic resistant gene variant or mutant; determinant of resistance to polyamine antibiotics; ARO_category; model_param "UPDATED category_aro_name with determinant of resistance to polyamine antibiotics UPDATED param_description with A parameter to describe the mapped insertion or deletion. For an insertion: insert the location and genetic sequence of the insertion. For a deletion: insert the location of the deletion. For nucleotide space: insertion: [nt][position]+[number of nucleotides]:[nucleotides] eg. nt312+1:G. For protein space: insertion: +[amino acids][start position:end position] eg. +S3:12. If both are known, a ""/"" may be used to separate the protein and nucleotide notation eg. nt312+3:AGC/+S312. " 367 UPDATE CTX-M-25 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 364 UPDATE CMY-83 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 365 UPDATE TEM-122 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 362 UPDATE CTX-M-151 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 363 UPDATE TEM-155 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 360 UPDATE AAC(6')-Iy antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 361 UPDATE OXA-278 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 380 UPDATE CTX-M-147 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 381 UPDATE QnrS1 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 382 UPDATE QnrB61 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 383 UPDATE Pseudomonas mutant PhoQ conferring resistance to colistin efflux pump complex or subunit conferring antibiotic resistance; determinant of polymyxin resistance; protein(s) and two-component regulatory system modulating antibiotic efflux; gene altering cell wall charge; ARO_category; model_name "UPDATED category_aro_name with determinant of polymyxin resistance UPDATED model_name with Pseudomonas mutant PhoQ conferring resistance to colistin " 384 UPDATE APH(2'')-IVa antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 385 UPDATE OXA-46 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 386 UPDATE LEN-8 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 388 UPDATE QnrB71 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 389 UPDATE tetW antibiotic target protection protein; determinant of tetracycline resistance; ARO_category "UPDATED category_aro_name with determinant of tetracycline resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to tetracycline antibiotics or tetracycline-like derivatives. " 1253 UPDATE GES-23 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1077 UPDATE OXA-420 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2191 UPDATE AAC(6')-Iaj antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 258 UPDATE OXA-208 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2196 UPDATE Pseudomonas aeruginosa gyrA conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 252 UPDATE APH(9)-Ia antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 253 UPDATE vanXYG determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 251 UPDATE APH(3')-VIIa antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 256 UPDATE CMY-21 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 257 UPDATE ACT-37 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 254 UPDATE OXA-150 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 255 UPDATE bleomycin resistance protein (BRP) determinant of resistance to glycopeptide antibiotics; gene involved in antibiotic sequestration; ARO_category; model_name; ARO_name "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. UPDATED model_name with determinant of bleomycin resistance UPDATED ARO_name with determinant of bleomycin resistance " 2200 UPDATE APH(3')-VI antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2201 UPDATE PvrR determinant of aminoglycoside resistance; gene conferring resistance via absence; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2202 UPDATE AAC(3)-Ib/AAC(6')-Ib'' antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2203 UPDATE MCR-1 determinant of polymyxin resistance; gene altering cell wall charge; ARO_category "UPDATED category_aro_name with determinant of polymyxin resistance " 2204 UPDATE AAC(6')-IId antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2205 UPDATE mexJ efflux pump complex or subunit conferring antibiotic resistance; ARO_name "UPDATED ARO_name with MexJ " 2206 UPDATE mexK efflux pump complex or subunit conferring antibiotic resistance; ARO_name "UPDATED ARO_name with MexK " 2207 UPDATE mexV efflux pump complex or subunit conferring antibiotic resistance; ARO_name "UPDATED ARO_name with MexV " 2208 UPDATE mexW efflux pump complex or subunit conferring antibiotic resistance; ARO_name "UPDATED ARO_name with MexW " 900 UPDATE tet(C) efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with tet(C) " 1848 UPDATE CTX-M-75 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 168 UPDATE VIM-17 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 169 UPDATE IMP-33 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 164 UPDATE vanN determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 165 UPDATE VIM-29 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 166 UPDATE TEM-77 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 167 UPDATE CMY-39 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 160 UPDATE OXA-236 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 161 UPDATE SHV-56 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 162 UPDATE KPC-8 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 163 UPDATE OXA-376 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2518 UPDATE tetB(48) efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with tetB(48) " 908 UPDATE CTX-M-139 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 909 UPDATE OXA-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1090 UPDATE TEM-169 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1091 UPDATE IMP-6 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1814 UPDATE AAC(6')-Ie-APH(2'')-Ia antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1815 UPDATE CTX-M-134 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1816 UPDATE TEM-8 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1810 UPDATE VIM-15 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1811 UPDATE CARB-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1812 UPDATE KHM-1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1813 UPDATE MOX-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1818 UPDATE GES-26 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1819 UPDATE TEM-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1098 UPDATE vanB determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1099 UPDATE OXA-48 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1609 UPDATE QnrC antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1608 UPDATE mexT efflux pump complex or subunit conferring antibiotic resistance; protein(s) and two-component regulatory system modulating antibiotic efflux; ARO_name; ARO_description; model_sequences; model_param; model_type; model_description; model_name; model_type_id "UPDATED ARO_name with MexT UPDATED ARO_description with MexT is a LysR-type transcriptional activator that positively regulates the expression of MexEF-OprN, OprD, and MexS. UPDATED fmax with 2807469 UPDATED strand with + UPDATED accession with NC_002516.2 UPDATED fmin with 2807468 UPDATED sequence with A UPDATED NCBI_taxonomy_name with Pseudomonas aeruginosa PAO1 UPDATED NCBI_taxonomy_id with 208964 UPDATED NCBI_taxonomy_cvterm_id with 36804 UPDATED GI with NP_251182.1 UPDATED sequence with MPVSDPMPLRHLARPRPVSHARLDGEPPRLQPLAPGNEERHEPKRPAPRRSEPADRVRDPDARTQRDPRRRETVPRPAGQPAISAALSRLRTLFDDPLFVRTGRSMEPTARAQEIFAHLSPALDSISTAMSRASEFDPATSTAVFRIGLSDDVEFGLLPPLLRRLRAEAPGFVLVVRRANYLLMPNLLASGEISVGVSYTDELPANAKRKTVRRSKPKILRADSAPGQLTLDDYCARPHALVSFAGDLSGFVDEELEKFGRKRKVVLAVPQFNGLGTLLAGTDIIATVPDYAAQALIAAGGLRAEDPPFETRAFELSMAWRGAQDNDPAERWLRSRISMFIGDPDSL UPDATED 7571 with Y138D UPDATED 7570 with G258D UPDATED 7571 with Y138D UPDATED 7570 with G258D UPDATED param_type with single resistance variant UPDATED param_type_id with 36301 UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). UPDATED model_type with presence and absence of protein variant model UPDATED model_description with This model detects the presence and absence of mutations in protein space. This model reflects how certain proteins are functional with and without mutations. For example, efflux pump subunits and regulators are functional with mutations and without mutations. Without mutations, efflux pump subunits and regulators are usually expressed at a low level. When an efflux pump subunit has a mutation, it can cause the drug resistance profile of the efflux pump to change. When an efflux pump regulator has a mutation, it can cause the overexpression of the efflux pump it is responsible for regulating, leading to resistance to specific drugs. Thus, the goal is to be able to detect the presence and absence of mutations in efflux pump subunits and regulators to identify a functional efflux pump system, as well as, a mutated and functional efflux pump system. UPDATED model_name with MexT UPDATED model_type_id with 41091 " 1979 UPDATE FosA4 antibiotic inactivation enzyme; determinant of fosfomycin resistance; ARO_category "UPDATED category_aro_name with determinant of fosfomycin resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fosfomycin antibiotics. " 1978 UPDATE OXA-200 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1601 UPDATE LRA-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1600 UPDATE Pseudomonas mutant PhoP conferring resistance to colistin efflux pump complex or subunit conferring antibiotic resistance; determinant of polymyxin resistance; protein(s) and two-component regulatory system modulating antibiotic efflux; gene altering cell wall charge; ARO_category; model_name "UPDATED category_aro_name with determinant of polymyxin resistance UPDATED model_name with Pseudomonas mutant PhoP conferring resistance to colistin " 1603 UPDATE SHV-86 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1602 UPDATE AAC(6')-Iai antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1605 UPDATE cphA5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1604 UPDATE CTX-M-84 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1607 UPDATE Streptococcus pneumoniae PBP1a conferring resistance to amoxicillin antibiotic resistant gene variant or mutant; determinant of beta-lactam resistance; ARO_category; model_name "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. UPDATED model_name with Streptococcus pneumoniae PBP1a conferring resistance to amoxicillin " 1606 UPDATE CTX-M-16 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 809 UPDATE lnuB determinant of lincosamide resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. " 808 UPDATE TEM-171 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 803 UPDATE cphA4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 802 UPDATE QnrA3 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 801 UPDATE mfpA antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 800 UPDATE CTX-M-87 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 807 UPDATE OKP-B-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 806 UPDATE SHV-150 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 805 UPDATE mexC efflux pump complex or subunit conferring antibiotic resistance; model_name; ARO_name "UPDATED model_name with MexC UPDATED ARO_name with MexC " 804 UPDATE tetB(P) antibiotic target protection protein; determinant of tetracycline resistance; ARO_category "UPDATED category_aro_name with determinant of tetracycline resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to tetracycline antibiotics or tetracycline-like derivatives. " 1775 UPDATE QnrS7 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1774 UPDATE CTX-M-106 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1777 UPDATE OXA-177 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1776 UPDATE SHV-159 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1771 UPDATE TEM-19 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1770 UPDATE TEM-127 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1773 UPDATE tet(43) efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with tet(43) " 1772 UPDATE aadA11 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1779 UPDATE CTX-M-12 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1778 UPDATE OKP-A-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1159 UPDATE TEM-129 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1158 UPDATE SHV-22 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1155 UPDATE ACT-9 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1154 UPDATE TEM-146 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1157 UPDATE vanG determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1156 UPDATE Erm(31) antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 1151 UPDATE OXA-240 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1150 UPDATE QnrVC5 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1153 UPDATE KPC-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1152 UPDATE CTX-M-39 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1555 UPDATE SHV-140 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1551 UPDATE OXA-78 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1553 UPDATE tetS antibiotic target protection protein; determinant of tetracycline resistance; ARO_category "UPDATED category_aro_name with determinant of tetracycline resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to tetracycline antibiotics or tetracycline-like derivatives. " 1552 UPDATE MUS-1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 59 UPDATE OXA-256 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 58 UPDATE QnrB47 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1557 UPDATE SHV-187 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1556 UPDATE VIM-13 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 55 UPDATE OXA-69 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 54 UPDATE TEM-34 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 57 UPDATE SHV-24 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 56 UPDATE TEM-7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 51 UPDATE AAC(3)-IIIc antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 50 UPDATE SME-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 53 UPDATE MOX-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 52 UPDATE OXY-2-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 537 UPDATE OXA-120 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 536 UPDATE TEM-95 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 535 UPDATE Morganella morganii gyrB conferring resistance to fluoroquinolone antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 534 UPDATE vanV determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 533 UPDATE CARB-16 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 532 UPDATE CTX-M-47 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 531 UPDATE SAT-3 determinant of resistance to nucleoside antibiotics; antibiotic inactivation enzyme; ARO_category; model_name "UPDATED category_aro_name with determinant of resistance to nucleoside antibiotics UPDATED model_name with SAT-3 " 530 UPDATE VIM-11 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 539 UPDATE QnrB59 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1558 UPDATE Bacillus subtilis mprF antibiotic target modifying enzyme; determinant of resistance to peptide antibiotics; ARO_category "UPDATED category_aro_name with determinant of resistance to peptide antibiotics " 428 UPDATE OXY-2-7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1399 UPDATE OXA-315 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1398 UPDATE OXA-108 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 421 UPDATE TEM-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 420 UPDATE CTX-M-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1395 UPDATE Neisseria gonorrhoeae mutant porin PIB (por) with reduced permeability to antibiotic determinant of tetracycline resistance; antibiotic resistant gene variant or mutant; determinant of beta-lactam resistance; protein modulating permeability to antibiotic; ARO_category "UPDATED category_aro_name with determinant of tetracycline resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to tetracycline antibiotics or tetracycline-like derivatives. UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 422 UPDATE FOX-10 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1393 UPDATE THIN-B beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 424 UPDATE SHV-36 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1391 UPDATE CTX-M-92 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 426 UPDATE aadK antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1443 UPDATE CARB-7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1321 UPDATE mecA antibiotic resistance gene cluster, cassette, or operon; determinant of beta-lactam resistance; antibiotic target replacement protein; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 229 UPDATE vanTmL determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 227 UPDATE OKP-B-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 226 UPDATE OXA-113 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 225 UPDATE CTX-M-88 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 224 UPDATE MIR-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 223 UPDATE GES-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 222 UPDATE JOHN-1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 221 UPDATE CMY-100 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 220 UPDATE TEM-92 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2215 UPDATE Pseudomonas aeruginosa gyrA and parC conferring resistance to fluoroquinolone gene involved in self-resistance to antibiotic; antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category; model_name "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics UPDATED model_name with Pseudomonas aeruginosa gyrA and parC conferring resistance to fluoroquinolone " 2219 UPDATE mexL efflux pump complex or subunit conferring antibiotic resistance; protein(s) and two-component regulatory system modulating antibiotic efflux; ARO_name "UPDATED ARO_name with MexL " 151 UPDATE OKP-A-15 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 150 UPDATE catB3 determinant of phenicol resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of phenicol resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to phenicol (chloramphenicol) antibiotics. These include chloramphenicol acetyltransferase (CAT) enzymes, which are found in a large number of species. " 155 UPDATE TEM-195 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 157 UPDATE dfrA21 antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 156 UPDATE AAC(6')-Iaf antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 158 UPDATE myrA antibiotic target modifying enzyme; gene involved in self-resistance to antibiotic; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. " 1293 UPDATE OXA-197 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2436 UPDATE D-Ala-D-Ala ligase determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; ARO_category; model_param "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. UPDATED param_description with A parameter to describe the mapped insertion or deletion. For an insertion: insert the location and genetic sequence of the insertion. For a deletion: insert the location of the deletion. For nucleotide space: insertion: [nt][position]+[number of nucleotides]:[nucleotides] eg. nt312+1:G. For protein space: insertion: +[amino acids][start position:end position] eg. +S3:12. If both are known, a ""/"" may be used to separate the protein and nucleotide notation eg. nt312+3:AGC/+S312. UPDATED param_value with 1e-100 UPDATED param_type_id with 36302 UPDATED param_type with BLASTP e-value UPDATED param_description with A curated expectation value (e-value) for assignment of an Antibiotic Resistance Ontology term based on a BLASTP hit to a CARD reference sequence. " 1807 UPDATE OXA-70 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1806 UPDATE OXA-14 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1805 UPDATE TEM-131 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1804 UPDATE OXA-107 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1803 UPDATE QnrVC3 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1802 UPDATE OXA-168 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1801 UPDATE AAC(6')-Ib11 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1800 UPDATE SHV-120 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1809 UPDATE QnrB5 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1808 UPDATE tet(A) efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with tet(A) " 1948 UPDATE TEM-167 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1949 UPDATE cphA6 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1257 UPDATE QnrB68 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1942 UPDATE BJP-1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category; model_name "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. UPDATED model_name with BJP-1 beta-lactamase " 1943 UPDATE Mycobacterium tuberculosis kasA mutant conferring resistance to isoniazid antibiotic resistant gene variant or mutant; determinant of isoniazid resistance; ARO_category "UPDATED category_aro_name with determinant of isoniazid resistance " 1940 UPDATE QnrB30 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1941 UPDATE SHV-98 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1946 UPDATE CTX-M-10 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1947 UPDATE CTX-M-160 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1944 UPDATE CTX-M-148 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1945 UPDATE SHV-50 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 818 UPDATE SHV-141 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 819 UPDATE CTX-M-68 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1255 UPDATE OXA-119 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 810 UPDATE mecC antibiotic resistance gene cluster, cassette, or operon; determinant of beta-lactam resistance; antibiotic target replacement protein; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 811 UPDATE TEM-26 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 812 UPDATE CMY-10 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 813 UPDATE OXA-216 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 814 UPDATE TEM-113 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 815 UPDATE GOB-1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 816 UPDATE OXA-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 817 UPDATE CTX-M-158 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1250 UPDATE CTX-M-96 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1622 UPDATE vanWG determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1251 UPDATE CTX-M-157 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1621 UPDATE SHV-45 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1490 UPDATE SHV-107 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1491 UPDATE lnuF determinant of lincosamide resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. " 1492 UPDATE MOX-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1493 UPDATE PER-6 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1494 UPDATE LAT-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1495 UPDATE ACT-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1496 UPDATE OXA-224 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1497 UPDATE dfrA10 antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 1498 UPDATE cphA8 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1499 UPDATE VEB-6 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 423 UPDATE DHA-16 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1700 UPDATE ACT-28 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1701 UPDATE Erm(39) antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 1702 UPDATE MIR-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1703 UPDATE FosK antibiotic inactivation enzyme; determinant of fosfomycin resistance; ARO_category "UPDATED category_aro_name with determinant of fosfomycin resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fosfomycin antibiotics. " 1704 UPDATE CMY-57 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1705 UPDATE SHV-111 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1706 UPDATE OXA-142 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1707 UPDATE QnrB4 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1708 UPDATE tet36 antibiotic target protection protein; determinant of tetracycline resistance; ARO_category "UPDATED category_aro_name with determinant of tetracycline resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to tetracycline antibiotics or tetracycline-like derivatives. " 1709 UPDATE TEM-115 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1392 UPDATE aadA22 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 427 UPDATE OCH-7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1629 UPDATE TEM-197 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1128 UPDATE OXA-23 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1129 UPDATE CMY-19 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1120 UPDATE IMI-7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1121 UPDATE APH(3')-VIa antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1122 UPDATE OXA-180 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1123 UPDATE FOX-8 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1124 UPDATE TEM-186 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1125 UPDATE OKP-B-11 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1126 UPDATE OXA-184 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1127 UPDATE CTX-M-64 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 524 UPDATE dfrA25 antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 525 UPDATE CMY-13 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 526 UPDATE ACT-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 527 UPDATE SHV-38 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1018 UPDATE APH(3')-IIc antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 521 UPDATE OXA-386 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 523 UPDATE OXA-75 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1014 UPDATE SHV-25 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 695 UPDATE CMY-66 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1016 UPDATE OXA-255 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1017 UPDATE CTX-M-86 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 528 UPDATE OCH-8 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 529 UPDATE SHV-185 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1012 UPDATE KPC-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1013 UPDATE APH(2'')-IIIa antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1234 UPDATE MIR-13 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1235 UPDATE AAC(6')-Ib' antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1236 UPDATE CMY-53 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1237 UPDATE Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin determinant of rifamycin resistance; antibiotic resistant gene variant or mutant; ARO_category; model_param "UPDATED category_aro_name with determinant of rifamycin resistance UPDATED category_aro_description with Enzymes, other proteins, or other gene products shown clinically to confer resistance to rifamycin (rifampin) antibiotics. UPDATED param_description with A parameter to describe the mapped insertion or deletion. For an insertion: insert the location and genetic sequence of the insertion. For a deletion: insert the location of the deletion. For nucleotide space: insertion: [nt][position]+[number of nucleotides]:[nucleotides] eg. nt312+1:G. For protein space: insertion: +[amino acids][start position:end position] eg. +S3:12. If both are known, a ""/"" may be used to separate the protein and nucleotide notation eg. nt312+3:AGC/+S312. " 1230 UPDATE CTX-M-33 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1233 UPDATE tet32 antibiotic target protection protein; determinant of tetracycline resistance; ARO_category "UPDATED category_aro_name with determinant of tetracycline resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to tetracycline antibiotics or tetracycline-like derivatives. " 1238 UPDATE OXA-397 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1239 UPDATE SHV-81 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " _version N/A N/A N/A N/A NEW: 1.1.6 , OLD: 1.1.5 438 UPDATE VIM-6 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 439 UPDATE SHV-83 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 436 UPDATE OXY-4-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 437 UPDATE SHV-69 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 434 UPDATE LEN-16 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 435 UPDATE OKP-A-9 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 433 UPDATE ACT-25 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 430 UPDATE OXA-87 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 431 UPDATE Escherichia coli marR mutant conferring antibiotic resistance efflux pump complex or subunit conferring antibiotic resistance; antibiotic resistant gene variant or mutant; protein(s) and two-component regulatory system modulating antibiotic efflux; model_type; model_description; model_name; model_param; model_type_id "UPDATED model_type with presence and absence of protein variant model UPDATED model_description with This model detects the presence and absence of mutations in protein space. This model reflects how certain proteins are functional with and without mutations. For example, efflux pump subunits and regulators are functional with mutations and without mutations. Without mutations, efflux pump subunits and regulators are usually expressed at a low level. When an efflux pump subunit has a mutation, it can cause the drug resistance profile of the efflux pump to change. When an efflux pump regulator has a mutation, it can cause the overexpression of the efflux pump it is responsible for regulating, leading to resistance to specific drugs. Thus, the goal is to be able to detect the presence and absence of mutations in efflux pump subunits and regulators to identify a functional efflux pump system, as well as, a mutated and functional efflux pump system. UPDATED model_name with Escherichia coli marR mutant conferring antibiotic resistance UPDATED 7640 with S3N UPDATED 7640 with S3N UPDATED model_type_id with 41091 " 1630 UPDATE IMP-13 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1961 UPDATE TEM-105 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 238 UPDATE SHV-137 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 239 UPDATE OXA-83 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 234 UPDATE QnrS8 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 235 UPDATE OXA-181 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 236 UPDATE ACT-19 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 237 UPDATE BlaB beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 230 UPDATE OXA-422 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 231 UPDATE OXA-178 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 232 UPDATE imiH antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 233 UPDATE LEN-21 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 993 UPDATE AAC(6')-Ib9 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2228 UPDATE PEDO-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2229 UPDATE PEDO-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2227 UPDATE VCC-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2224 UPDATE Pseudomonas aeruginosa oprD with mutation conferring resistance to imipenem protein modulating permeability to antibiotic; model_name "UPDATED model_name with Pseudomonas aeruginosa oprD with mutation conferring resistance to imipenem " 2222 UPDATE VEB-1b antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2223 UPDATE mexZ efflux pump complex or subunit conferring antibiotic resistance; protein(s) and two-component regulatory system modulating antibiotic efflux; ARO_description; model_type; model_type_id; ARO_name; model_description "UPDATED ARO_description with MexZ is a transcriptional regulator that downregulates the mexXY multidrug transporter operon, which confers to aminoglycoside resistance on Pseudomonas aeruginosa. UPDATED model_type with presence and absence of protein variant model UPDATED model_type_id with 41091 UPDATED ARO_name with MexZ UPDATED model_description with This model detects the presence and absence of mutations in protein space. This model reflects how certain proteins are functional with and without mutations. For example, efflux pump subunits and regulators are functional with mutations and without mutations. Without mutations, efflux pump subunits and regulators are usually expressed at a low level. When an efflux pump subunit has a mutation, it can cause the drug resistance profile of the efflux pump to change. When an efflux pump regulator has a mutation, it can cause the overexpression of the efflux pump it is responsible for regulating, leading to resistance to specific drugs. Thus, the goal is to be able to detect the presence and absence of mutations in efflux pump subunits and regulators to identify a functional efflux pump system, as well as, a mutated and functional efflux pump system. " 2221 UPDATE VEB-1a antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1 UPDATE PDC-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 146 UPDATE OXA-98 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 147 UPDATE OXA-27 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 144 UPDATE IMP-12 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 145 UPDATE OXA-229 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 142 UPDATE tet(E) efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with tet(E) " 143 UPDATE cphA7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 140 UPDATE AAC(6')-IIb antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 141 UPDATE vanRB determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 148 UPDATE SHV-92 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 149 UPDATE aadA12 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2088 UPDATE Mycobacterium smegmatis 16S rRNA (rrsB) mutation conferring resistance to streptomycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2083 UPDATE Mycoplasma hominis parC conferring resistance to fluoroquinolone gene involved in self-resistance to antibiotic; antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 2080 UPDATE Escherichia coli 16S rRNA (rrsH) mutation conferring resistance to spectinomycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2086 UPDATE Escherichia coli 16S rRNA (rrnB) mutation conferring resistance to tetracycline antibiotic resistant gene variant or mutant; determinant of tetracycline resistance; ARO_category "UPDATED category_aro_name with determinant of tetracycline resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to tetracycline antibiotics or tetracycline-like derivatives. " 2087 UPDATE aadA13 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2084 UPDATE Mycobacterium abscessus 16S rRNA mutation conferring resistance to amikacin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2085 UPDATE Escherichia coli 16S rRNA (rrnB) mutation conferring resistance to spectinomycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1832 UPDATE QnrS2 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1833 UPDATE OXA-374 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1830 UPDATE APH(3'')-Ib antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1831 UPDATE AAC(6')-Iid antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1836 UPDATE OXA-201 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1837 UPDATE CTX-M-59 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1834 UPDATE TEM-94 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1835 UPDATE tet(38) efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with tet(38) " 1838 UPDATE ACT-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1839 UPDATE aadA14 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2154 UPDATE Borrelia burgdorferi 16S rRNA mutation conferring resistance to spectinomycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2155 UPDATE Propionibacterium acnes 16S rRNA mutation conferring resistance to tetracycline antibiotic resistant gene variant or mutant; determinant of tetracycline resistance; ARO_category "UPDATED category_aro_name with determinant of tetracycline resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to tetracycline antibiotics or tetracycline-like derivatives. " 2156 UPDATE NDM-14 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2157 UPDATE Escherichia coli 16S rRNA (rrsB) mutation conferring resistance to gentamicin C antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2402 UPDATE Haemophilus parainfluenzae parC conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 2403 UPDATE Salmonella enterica gyrA conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 2152 UPDATE Neisseria meningitidis 16S rRNA mutation conferring resistance to spectinomycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2401 UPDATE Haemophilus parainfluenzae gyrA conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 933 UPDATE OKP-A-14 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 932 UPDATE GES-8 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 931 UPDATE OXA-316 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 937 UPDATE OXA-242 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 936 UPDATE OKP-A-13 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 935 UPDATE OXA-314 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2409 UPDATE Neisseria meningititis PBP2 conferring resistance to beta-lactam antibiotic resistant gene variant or mutant; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1955 UPDATE OXA-29 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1954 UPDATE TEM-154 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1957 UPDATE VIM-18 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1956 UPDATE IMI-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1951 UPDATE TEM-76 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1950 UPDATE arr-1 determinant of rifamycin resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of rifamycin resistance UPDATED category_aro_description with Enzymes, other proteins, or other gene products shown clinically to confer resistance to rifamycin (rifampin) antibiotics. " 1953 UPDATE SHV-155 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1952 UPDATE OXA-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1959 UPDATE ACT-7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1958 UPDATE VIM-33 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 829 UPDATE DHA-17 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 828 UPDATE TEM-83 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 825 UPDATE SHV-20 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 824 UPDATE vanD determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 827 UPDATE QnrB55 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 826 UPDATE tolC efflux pump complex or subunit conferring antibiotic resistance; ARO_name "UPDATED ARO_name with TolC " 821 UPDATE Mycobacterium tuberculosis embB mutants conferring resistance to rifampicin determinant of rifamycin resistance; antibiotic resistant gene variant or mutant; ARO_category "UPDATED category_aro_name with determinant of rifamycin resistance UPDATED category_aro_description with Enzymes, other proteins, or other gene products shown clinically to confer resistance to rifamycin (rifampin) antibiotics. " 823 UPDATE cat determinant of phenicol resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of phenicol resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to phenicol (chloramphenicol) antibiotics. These include chloramphenicol acetyltransferase (CAT) enzymes, which are found in a large number of species. " 822 UPDATE QnrD1 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1483 UPDATE AAC(3)-Xa antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1482 UPDATE SME-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1481 UPDATE OXY-1-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1480 UPDATE EXO beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1487 UPDATE SHV-48 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1486 UPDATE CARB-12 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1485 UPDATE MOX-8 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1484 UPDATE ACT-27 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1489 UPDATE CMY-37 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1488 UPDATE TEM-75 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 797 UPDATE TEM-55 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2411 UPDATE Shigella flexneri gyrA conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 795 UPDATE OXA-324 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 794 UPDATE Staphylococcus aureus rpoC conferring resistance to daptomycin antibiotic resistant gene variant or mutant; determinant of resistance to lipopeptide antibiotics; ARO_category "UPDATED category_aro_name with determinant of resistance to lipopeptide antibiotics " 793 UPDATE IMP-34 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 792 UPDATE OXY-1-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 791 UPDATE SHV-14 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 929 UPDATE GES-10 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1718 UPDATE DIM-1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category; model_name "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. UPDATED model_name with DIM-1 beta-lactamase " 799 UPDATE CTX-M-31 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 612 UPDATE PDC-7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2144 UPDATE Mycobacterium bovis embB mutations conferring resistance to ethambutol antibiotic resistant gene variant or mutant; determinant of resistance to polyamine antibiotics; ARO_category "UPDATED category_aro_name with determinant of resistance to polyamine antibiotics " 1271 UPDATE AAC(6')-Iw antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1272 UPDATE CTX-M-67 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1139 UPDATE dfrA12 antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 1138 UPDATE tet(D) efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with tet(D) " 1133 UPDATE SHV-109 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1132 UPDATE OXA-88 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1131 UPDATE AAC(3)-Ic antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1130 UPDATE PDC-9 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1137 UPDATE TEM-90 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1136 UPDATE MIR-6 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1135 UPDATE Staphylococcus aureus parE conferring resistance to aminocoumarin determinant of aminocoumarin resistance; antibiotic resistant gene variant or mutant; ARO_category "UPDATED category_aro_name with determinant of aminocoumarin resistance " 1134 UPDATE linB determinant of lincosamide resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. " 1276 UPDATE OXA-210 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1277 UPDATE GES-16 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 519 UPDATE VIM-26 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 518 UPDATE vanXYN determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 926 UPDATE KPC-15 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1009 UPDATE IND-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1008 UPDATE BEL-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1007 UPDATE OKP-A-8 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1006 UPDATE tet(V) efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with tet(V) " 513 UPDATE CARB-19 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 927 UPDATE OXA-381 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 515 UPDATE mgtA determinant of macrolide resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. " 1002 UPDATE AAC(6')-Ib4 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1001 UPDATE Staphylococcus aureus mprF mutations conferring resistance to daptomycin determinant of resistance to peptide antibiotics; antibiotic resistant gene variant or mutant; determinant of resistance to lipopeptide antibiotics; ARO_category "UPDATED category_aro_name with determinant of resistance to peptide antibiotics UPDATED category_aro_name with determinant of resistance to lipopeptide antibiotics " 1000 UPDATE AAC(6')-Ib-Hangzhou antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 623 UPDATE OXA-68 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 622 UPDATE DHA-7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1225 UPDATE TEM-178 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 620 UPDATE OXA-320 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1223 UPDATE viomycin phosphotransferase determinant of resistance to peptide antibiotics; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of resistance to peptide antibiotics " 626 UPDATE vanHB determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 625 UPDATE QnrB46 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 624 UPDATE Mycobacterium leprae rpoB mutations conferring resistance to rifampicin determinant of rifamycin resistance; antibiotic resistant gene variant or mutant; ARO_category; model_name "UPDATED category_aro_name with determinant of rifamycin resistance UPDATED category_aro_description with Enzymes, other proteins, or other gene products shown clinically to confer resistance to rifamycin (rifampin) antibiotics. UPDATED model_name with Mycobacterium leprae rpoB mutations conferring resistance to rifampicin " 629 UPDATE VIM-28 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 628 UPDATE catB10 determinant of phenicol resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of phenicol resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to phenicol (chloramphenicol) antibiotics. These include chloramphenicol acetyltransferase (CAT) enzymes, which are found in a large number of species. " 1229 UPDATE CTX-M-6 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1228 UPDATE CMY-30 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2 UPDATE CblA-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1714 UPDATE ErmW antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 11 UPDATE Erm(34) antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 10 UPDATE CARB-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 13 UPDATE LRA-12 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 12 UPDATE TEM-126 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 15 UPDATE TEM-59 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 14 UPDATE TEM-72 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 17 UPDATE tet(45) efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with tet(45) " 16 UPDATE KPC-10 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 19 UPDATE IMP-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 18 UPDATE OXA-212 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 201 UPDATE OCH-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 200 UPDATE LEN-14 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 203 UPDATE OXY-2-8 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 202 UPDATE SHV-101 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 205 UPDATE APH(4)-Ia antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 204 UPDATE VIM-43 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 207 UPDATE GES-12 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 206 UPDATE FomA antibiotic inactivation enzyme; determinant of fosfomycin resistance; ARO_category "UPDATED category_aro_name with determinant of fosfomycin resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fosfomycin antibiotics. " 209 UPDATE AAC(3)-Ib/AAC(6')-Ib'' antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 208 UPDATE CMY-105 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1573 UPDATE SHV-110 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1572 UPDATE OXA-205 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1571 UPDATE vanSE determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1570 UPDATE oprA efflux pump complex or subunit conferring antibiotic resistance; ARO_name "UPDATED ARO_name with OprA " 2231 UPDATE CPS-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2230 UPDATE PEDO-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2233 UPDATE MSI-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2232 UPDATE ESP-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2235 UPDATE SPG-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2234 UPDATE MSI-OXA antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1576 UPDATE OXA-17 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1575 UPDATE OXA-91 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1574 UPDATE Mycobacterium tuberculosis inhA mutations conferring resistance to isoniazid antibiotic resistant gene variant or mutant; determinant of isoniazid resistance; determinant of triclosan resistance; ARO_category "UPDATED category_aro_name with determinant of isoniazid resistance UPDATED category_aro_name with determinant of triclosan resistance " 2097 UPDATE Escherichia coli 16S rRNA (rrsB) mutation conferring resistance to paromomycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2096 UPDATE Escherichia coli 16S rRNA (rrsC) mutation conferring resistance to kasugamicin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2091 UPDATE Mycobacterium chelonae 16S rRNA mutation conferring resistance to gentamicin C antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2090 UPDATE Mycobacterium abscessus 16S rRNA mutation conferring resistance to kanamycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2093 UPDATE Chlamydophila psittaci 16S rRNA mutation conferring resistance to spectinomycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2092 UPDATE Enterobacter aerogenes acrR mutation conferring antibiotic resistance efflux pump complex or subunit conferring antibiotic resistance; antibiotic resistant gene variant or mutant; protein(s) and two-component regulatory system modulating antibiotic efflux; model_param; ARO_name; model_name "UPDATED param_description with A parameter to describe the mapped insertion or deletion. For an insertion: insert the location and genetic sequence of the insertion. For a deletion: insert the location of the deletion. For nucleotide space: insertion: [nt][position]+[number of nucleotides]:[nucleotides] eg. nt312+1:G. For protein space: insertion: +[amino acids][start position:end position] eg. +S3:12. If both are known, a ""/"" may be used to separate the protein and nucleotide notation eg. nt312+3:AGC/+S312. UPDATED 7538 with A47fs UPDATED param_type_id with 40494 UPDATED param_type with frameshift UPDATED param_description with Insertion or deletion causing a frameshift mutation. These may contain data on the new STOP codon location if reported in the literature. For example, the notation for a frameshift after K136 creating a new STOP codon at P167 is: K136fs;P167STOP. If new STOP is unknown, K136fs is sufficient. UPDATED ARO_name with Enterobacter aerogenes acrR with mutation conferring multidrug antibiotic resistance UPDATED model_name with Enterobacter aerogenes acrR with mutation conferring multidrug antibiotic resistance " 2099 UPDATE Mycobacterium smegmatis 16S rRNA (rrsB) mutation conferring resistance to kanamycin A antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2098 UPDATE Mycobacterium smegmatis 16S rRNA (rrsB) mutation conferring resistance to viomycin determinant of resistance to peptide antibiotics; antibiotic resistant gene variant or mutant; ARO_category "UPDATED category_aro_name with determinant of resistance to peptide antibiotics " 2525 UPDATE AAC(6')-34 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2524 UPDATE AAC(2')-IIb antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2527 UPDATE mphI antibiotic inactivation enzyme; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. " 2526 UPDATE VgbC antibiotic inactivation enzyme; determinant of streptogramin resistance; ARO_category "UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 2521 UPDATE BahA determinant of resistance to peptide antibiotics; ARO_category "UPDATED category_aro_name with determinant of resistance to peptide antibiotics " 2520 UPDATE CatU determinant of phenicol resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of phenicol resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to phenicol (chloramphenicol) antibiotics. These include chloramphenicol acetyltransferase (CAT) enzymes, which are found in a large number of species. " 2523 UPDATE VatI antibiotic inactivation enzyme; determinant of streptogramin resistance; ARO_category "UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 2522 UPDATE TaeA efflux pump complex or subunit conferring antibiotic resistance; model_param "UPDATED param_value with 1e-150 UPDATED param_value with 1200 " 2529 UPDATE cpaA determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2528 UPDATE rphB determinant of rifamycin resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of rifamycin resistance UPDATED category_aro_description with Enzymes, other proteins, or other gene products shown clinically to confer resistance to rifamycin (rifampin) antibiotics. " 1829 UPDATE CMY-87 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1828 UPDATE GES-6 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1825 UPDATE CTX-M-27 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1824 UPDATE oleI determinant of macrolide resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. " 1827 UPDATE SHV-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1821 UPDATE AAC(6')-Ir antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1820 UPDATE bacA determinant of resistance to peptide antibiotics; gene conferring antibiotic resistance via molecular bypass; ARO_category "UPDATED category_aro_name with determinant of resistance to peptide antibiotics " 1823 UPDATE OXY-1-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1822 UPDATE Staphylococcus aureus gyrB conferring resistance to aminocoumarin determinant of aminocoumarin resistance; antibiotic resistant gene variant or mutant; ARO_category "UPDATED category_aro_name with determinant of aminocoumarin resistance " 2147 UPDATE Escherichia coli EF-Tu mutants conferring resistance to Enacyloxin IIa antibiotic resistant gene variant or mutant; determinant of elfamycin resistance; ARO_category "UPDATED category_aro_name with determinant of elfamycin resistance " 2146 UPDATE Escherichia coli 16S rRNA (rrnB) mutation conferring resistance to streptomycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2145 UPDATE Escherichia coli 16S rRNA (rrsB) mutation conferring resistance to tetracycline antibiotic resistant gene variant or mutant; determinant of tetracycline resistance; ARO_category "UPDATED category_aro_name with determinant of tetracycline resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to tetracycline antibiotics or tetracycline-like derivatives. " 2412 UPDATE Shigella flexneri parC conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 2143 UPDATE Borrelia burgdorferi 16S rRNA mutation conferring resistance to gentamicin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2142 UPDATE Mycobacterium smegmatis 16S rRNA (rrsA) mutation conferring resistance to viomycin determinant of resistance to peptide antibiotics; antibiotic resistant gene variant or mutant; ARO_category "UPDATED category_aro_name with determinant of resistance to peptide antibiotics " 2141 UPDATE Mycobacterium smegmatis 16S rRNA (rrsB) mutation conferring resistance to neomycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2140 UPDATE Escherichia coli 16S rRNA (rrsB) mutation conferring resistance to streptomycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 920 UPDATE TEM-152 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 921 UPDATE OKP-A-11 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 922 UPDATE AAC(6')-30/AAC(6')-Ib' fusion protein antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 923 UPDATE VIM-25 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 924 UPDATE AAC(6')-33 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 925 UPDATE AAC(3)-IIb antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2149 UPDATE Mycobacterium smegmatis 16S rRNA (rrsA) mutation conferring resistance to hygromycin B antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2148 UPDATE Ureaplasma urealyticum gyrB conferring resistance to fluoroquinolone antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1920 UPDATE vanSF determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1921 UPDATE EreB antibiotic inactivation enzyme; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. " 1923 UPDATE APH(3'')-Ia antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1924 UPDATE vanM determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1925 UPDATE mexB efflux pump complex or subunit conferring antibiotic resistance; model_name; ARO_name "UPDATED model_name with MexB UPDATED ARO_name with MexB " 1926 UPDATE CMY-34 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1927 UPDATE SHV-29 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1928 UPDATE OXA-50 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1929 UPDATE ACT-24 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 832 UPDATE SHV-161 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 833 UPDATE CfxA5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 830 UPDATE SHV-157 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 831 UPDATE OKP-B-13 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 836 UPDATE TEM-68 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 837 UPDATE vatH antibiotic inactivation enzyme; determinant of streptogramin resistance; ARO_category "UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 834 UPDATE FosA3 antibiotic inactivation enzyme; determinant of fosfomycin resistance; ARO_category "UPDATED category_aro_name with determinant of fosfomycin resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fosfomycin antibiotics. " 835 UPDATE APH(3')-Ib antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 838 UPDATE CTX-M-102 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 839 UPDATE CMY-44 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 3 UPDATE Escherichia coli ompF with mutation antibiotic resistant gene variant or mutant; determinant of beta-lactam resistance; protein modulating permeability to antibiotic; ARO_category; model_name "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. UPDATED model_name with Escherichia coli ompF with mutation " 784 UPDATE AAC(6')-Iv antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 785 UPDATE OXY-2-9 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 786 UPDATE vanHO determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 787 UPDATE dfrA23 antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 780 UPDATE CARB-9 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 781 UPDATE QnrB25 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 782 UPDATE OXA-63 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1729 UPDATE CTX-M-66 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1726 UPDATE FOX-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1727 UPDATE SHV-73 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1724 UPDATE vanHM determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1725 UPDATE TEM-101 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 788 UPDATE SHV-46 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 789 UPDATE IMP-43 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1721 UPDATE Mycobacterium leprae folP with mutation conferring resistance to dapsone antibiotic resistant gene variant or mutant; determinant of sulfonamide resistance; ARO_category; model_name "UPDATED category_aro_name with determinant of sulfonamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to sulfonamide antibiotics. UPDATED model_name with Mycobacterium leprae folP with mutation conferring resistance to dapsone " 60 UPDATE QnrS6 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 61 UPDATE OXA-330 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 62 UPDATE CMY-42 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 63 UPDATE AAC(6')-Ib antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 64 UPDATE CMY-70 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 65 UPDATE GES-21 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 66 UPDATE SHV-41 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 67 UPDATE OXA-391 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 68 UPDATE TEM-132 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 69 UPDATE aadA23 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1371 UPDATE CTX-M-26 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1588 UPDATE QnrB50 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1589 UPDATE PER-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 406 UPDATE ACC-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1582 UPDATE dfrA5 antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 1583 UPDATE QnrVC6 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1580 UPDATE catIII determinant of phenicol resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of phenicol resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to phenicol (chloramphenicol) antibiotics. These include chloramphenicol acetyltransferase (CAT) enzymes, which are found in a large number of species. " 1581 UPDATE ACT-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1586 UPDATE CTX-M-32 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1373 UPDATE CMY-26 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1584 UPDATE tet(41) efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with tet(41) " 1585 UPDATE CMY-73 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 404 UPDATE OXA-217 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 509 UPDATE FOX-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1032 UPDATE OXA-365 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 403 UPDATE dfrA8 antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 504 UPDATE TEM-52 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1031 UPDATE APH(6)-Id antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 502 UPDATE aadA17 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 503 UPDATE CTX-M-69 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 500 UPDATE OXA-164 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 402 UPDATE tet(Y) efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with tet(Y) " 1212 UPDATE OXA-141 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 631 UPDATE TEM-21 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 632 UPDATE basR determinant of polymyxin resistance; gene altering cell wall charge; ARO_category; model_name "UPDATED category_aro_name with determinant of polymyxin resistance UPDATED model_name with basR " 1211 UPDATE VIM-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1216 UPDATE SHV-119 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 401 UPDATE ACT-22 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 636 UPDATE CFE-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 637 UPDATE OXY-6-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 638 UPDATE ACT-16 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 639 UPDATE AAC(3)-IV antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1218 UPDATE TEM-219 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1219 UPDATE vanRN determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1728 UPDATE OXA-42 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 783 UPDATE NDM-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1454 UPDATE CMY-112 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1455 UPDATE IND-9 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1456 UPDATE IMP-15 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1457 UPDATE CTX-M-13 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1450 UPDATE Escherichia coli parC conferring resistance to fluoroquinolone gene involved in self-resistance to antibiotic; antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1103 UPDATE CMY-17 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1452 UPDATE TEM-216 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1453 UPDATE vanYD determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1458 UPDATE TEM-157 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1459 UPDATE CTX-M-78 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1108 UPDATE Enterococcus faecium liaS mutant conferring daptomycin resistance determinant of resistance to peptide antibiotics; antibiotic resistant gene variant or mutant; determinant of resistance to lipopeptide antibiotics; ARO_category "UPDATED category_aro_name with determinant of resistance to peptide antibiotics UPDATED category_aro_name with determinant of resistance to lipopeptide antibiotics " 1109 UPDATE CAU-1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1722 UPDATE TEM-184 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1723 UPDATE IMP-44 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1577 UPDATE AAC(6')-32 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 959 UPDATE OXA-64 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 958 UPDATE OXA-418 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 216 UPDATE LEN-9 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 217 UPDATE vanXA determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 214 UPDATE SHV-121 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 215 UPDATE bcrC determinant of resistance to peptide antibiotics; gene conferring antibiotic resistance via molecular bypass; ARO_category "UPDATED category_aro_name with determinant of resistance to peptide antibiotics " 213 UPDATE OXA-21 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 210 UPDATE SHV-35 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 211 UPDATE TEM-206 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 218 UPDATE npmA antibiotic target modifying enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 219 UPDATE OKP-A-12 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 957 UPDATE tet(G) efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with tet(G) " 956 UPDATE TEM-88 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 4 UPDATE SHV-52 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2550 UPDATE Clostridium difficile gyrA conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 2396 UPDATE OXA-368 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category; model_param "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. UPDATED param_value with 1e-150 UPDATED param_type_id with 36302 UPDATED param_type with BLASTP e-value UPDATED param_description with A curated expectation value (e-value) for assignment of an Antibiotic Resistance Ontology term based on a BLASTP hit to a CARD reference sequence. " 2397 UPDATE pgpB determinant of polymyxin resistance; gene altering cell wall charge; ARO_category; model_name "UPDATED category_aro_name with determinant of polymyxin resistance UPDATED model_name with pgpB " 2395 UPDATE apmA antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2398 UPDATE TEM-220 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1858 UPDATE OXA-387 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1859 UPDATE QnrVC7 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1850 UPDATE FomB antibiotic inactivation enzyme; determinant of fosfomycin resistance; ARO_category "UPDATED category_aro_name with determinant of fosfomycin resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fosfomycin antibiotics. " 1851 UPDATE KPC-13 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1852 UPDATE rmtF antibiotic target modifying enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1853 UPDATE OXA-20 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1854 UPDATE rmtA antibiotic target modifying enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1855 UPDATE CTX-M-72 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1856 UPDATE QnrB20 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1857 UPDATE VIM-9 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 919 UPDATE PER-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 918 UPDATE TEM-49 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 915 UPDATE SHV-106 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 914 UPDATE ANT(6)-Ia antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 917 UPDATE SHV-186 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 916 UPDATE OXA-36 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 911 UPDATE CMY-50 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 910 UPDATE rphA determinant of rifamycin resistance; antibiotic inactivation enzyme; ARO_category; model_name "UPDATED category_aro_name with determinant of rifamycin resistance UPDATED category_aro_description with Enzymes, other proteins, or other gene products shown clinically to confer resistance to rifamycin (rifampin) antibiotics. UPDATED model_name with rphA " 913 UPDATE OXY-6-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 912 UPDATE LEN-13 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 516 UPDATE PmrC determinant of polymyxin resistance; gene altering cell wall charge; ARO_category "UPDATED category_aro_name with determinant of polymyxin resistance " 1420 UPDATE aadA5 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1933 UPDATE SHV-160 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1932 UPDATE IMP-32 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1931 UPDATE TEM-150 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1930 UPDATE CTX-M-29 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1937 UPDATE OXA-118 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1936 UPDATE CTX-M-43 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1935 UPDATE Mycobacterium tuberculosis gyrA conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1934 UPDATE lnuD determinant of lincosamide resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. " 1939 UPDATE AAC(6')-Ix antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1424 UPDATE OXY-2-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 847 UPDATE CTX-M-108 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 846 UPDATE DHA-12 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 845 UPDATE TEM-163 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 844 UPDATE CMY-117 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 843 UPDATE QnrB14 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 842 UPDATE PmrE determinant of polymyxin resistance; gene altering cell wall charge; ARO_category "UPDATED category_aro_name with determinant of polymyxin resistance " 841 UPDATE CTX-M-14 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 840 UPDATE CMY-20 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1426 UPDATE IMP-7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 849 UPDATE OXA-138 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 848 UPDATE OKP-A-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 663 UPDATE ACT-36 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1587 UPDATE OXA-10 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1739 UPDATE SHV-16 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1738 UPDATE CTX-M-45 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1731 UPDATE mphB determinant of macrolide resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. " 1730 UPDATE OXA-235 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1733 UPDATE OXA-415 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1732 UPDATE SHV-151 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 662 UPDATE TEM-162 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1734 UPDATE IND-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1737 UPDATE ANT(4')-Ia antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1736 UPDATE GES-24 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1039 UPDATE dfrB3 antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 753 UPDATE SMB-1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 752 UPDATE vanRM determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 751 UPDATE TEM-217 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 750 UPDATE SHV-172 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 757 UPDATE CMY-80 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 756 UPDATE Enterococcus faecium liaR mutant conferring daptomycin resistance determinant of resistance to peptide antibiotics; antibiotic resistant gene variant or mutant; determinant of resistance to lipopeptide antibiotics; ARO_category "UPDATED category_aro_name with determinant of resistance to peptide antibiotics UPDATED category_aro_name with determinant of resistance to lipopeptide antibiotics " 755 UPDATE KPC-9 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 754 UPDATE CTX-M-48 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 759 UPDATE OCH-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 758 UPDATE OXA-198 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1595 UPDATE mecB antibiotic resistance gene cluster, cassette, or operon; determinant of beta-lactam resistance; antibiotic target replacement protein; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 506 UPDATE IMP-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1597 UPDATE SHV-2A antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1596 UPDATE OXA-24 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1591 UPDATE CMY-64 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1590 UPDATE QnrB27 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1593 UPDATE CMY-99 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1592 UPDATE dfrA14 antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 1599 UPDATE SHV-23 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1030 UPDATE vanZA determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1025 UPDATE TEM-136 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1024 UPDATE AAC(6')-Ib-SK antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1027 UPDATE tet(H) efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with tet(H) " 1026 UPDATE SHV-74 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1021 UPDATE CTX-M-54 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1020 UPDATE OXA-241 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1023 UPDATE IMP-14 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1022 UPDATE TEM-28 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1036 UPDATE vanWB determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1029 UPDATE CMY-102 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1028 UPDATE SHV-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1034 UPDATE QnrA7 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 501 UPDATE AAC(3)-VIIIa antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 605 UPDATE OXA-96 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 604 UPDATE OXA-385 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 607 UPDATE TEM-201 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 606 UPDATE IMI-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 601 UPDATE dfrA20 antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 600 UPDATE CMY-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 602 UPDATE VIM-16 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1205 UPDATE VIM-39 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1207 UPDATE DHA-13 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1201 UPDATE CARB-22 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 608 UPDATE OXA-361 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1203 UPDATE Mycobacterium tuberculosis ndh mutant conferring resistance to isoniazid antibiotic resistant gene variant or mutant; determinant of isoniazid resistance; ARO_category "UPDATED category_aro_name with determinant of isoniazid resistance " 1202 UPDATE CTX-M-28 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 633 UPDATE OXA-355 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1217 UPDATE OXA-139 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1214 UPDATE TEM-134 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1215 UPDATE FosC antibiotic inactivation enzyme; determinant of fosfomycin resistance; ARO_category "UPDATED category_aro_name with determinant of fosfomycin resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fosfomycin antibiotics. " 1111 UPDATE AAC(6')-Ig antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1110 UPDATE LEN-19 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1113 UPDATE ANT(6)-Ib antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1112 UPDATE OXA-58 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1115 UPDATE OXA-435 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1114 UPDATE ACT-17 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1117 UPDATE ErmD antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 1440 UPDATE CTX-M-103 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1119 UPDATE EBR-1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1118 UPDATE OXA-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1351 UPDATE QnrVC1 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1449 UPDATE OXA-59 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1448 UPDATE SHV-26 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1350 UPDATE TEM-93 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 461 UPDATE OXA-13 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1356 UPDATE dfrA22 antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 463 UPDATE CTX-M-30 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 489 UPDATE Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin antibiotic target modifying enzyme; antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category; model_param "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. UPDATED param_description with A parameter to describe the mapped insertion or deletion. For an insertion: insert the location and genetic sequence of the insertion. For a deletion: insert the location of the deletion. For nucleotide space: insertion: [nt][position]+[number of nucleotides]:[nucleotides] eg. nt312+1:G. For protein space: insertion: +[amino acids][start position:end position] eg. +S3:12. If both are known, a ""/"" may be used to separate the protein and nucleotide notation eg. nt312+3:AGC/+S312. " 488 UPDATE SHV-156 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 485 UPDATE TEM-191 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 484 UPDATE QnrB49 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 483 UPDATE GES-7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 482 UPDATE LEN-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 481 UPDATE VIM-30 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 480 UPDATE GES-9 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 199 UPDATE SRT-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 198 UPDATE TEM-138 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 195 UPDATE CTX-M-58 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 194 UPDATE SHV-61 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 197 UPDATE CTX-M-56 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 196 UPDATE Mycobacterium tuberculosis embB mutations conferring resistance to ethambutol antibiotic resistant gene variant or mutant; determinant of resistance to polyamine antibiotics; ARO_category "UPDATED category_aro_name with determinant of resistance to polyamine antibiotics " 191 UPDATE OXA-199 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 190 UPDATE OXA-195 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 193 UPDATE TEM-121 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 192 UPDATE CTX-M-38 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1106 UPDATE NDM-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1107 UPDATE PDC-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1104 UPDATE acrB efflux pump complex or subunit conferring antibiotic resistance; model_sequences "UPDATED fmax with 484403 UPDATED strand with - UPDATED accession with NC_000913.3 UPDATED fmin with 481253 UPDATED sequence with TCAATGATGATCGACAGTATGGCTGTGCTCGATATCTTCATTCTTGCGGCTAAAGCGGCGGCGAACCACCACAAAGAATACCGGAACGAAGAAGATTGCCAGTACCGTTGCGGTCACCATCCCGCCCATTACACCGGTACCTACTGCGTTCTGCGCGCCGGAACCAGCACCAGTACTGATAACCAGCGGCATAACGCCGAGGATAAACGCCAGCGAGGTCATCAGGATCGGACGTAAACGCATCCGCACCGCATCAAGCGTCGCTTCAATCAGACCTTTACCTTCTTTATCCATCAAGTCTTTGGCGAATTCGACGATAAGGATCGCGTTCTTCGCCGACAACCCAATGGTTGTGAGCAGGCCTACCTGGAAGTAAACGTCATTGGTCAGGCCACGGAAGGTGGCAGCCAGCAACGCACCGATAACCCCCAGCGGAACGACCAGCATAACGGAGAACGGAATCGACCAGCTCTCGTACAGCGCCGCCAGACACAGGAACACGACAATCAACGAAATCGCGTACAGTGAAGGTGCCTGGTTGCCGGAGAGACGTTCCTGATAGGACATCCCCGTCCAGTCATAGCCAACACCGGTAGGCAGTTTGCTCGCCAGTTGTTCCATCAGCTCCATTGCTTCACCGGTACTTTTACCCGGTGCCGCCTGGCCTAAGATTTCCATGGATGGCAGGCCGTTGTAACGTTCCAGACGCGGCGAACCGTACTCCCAACGAGAAGAGGAGAACGCCGAGAATGGCACCATCTGACCATCAGCAGCACGAACATACCAGTCGCCGATATCATCCGGCAGCATACGGTATTTCGCTTCTGACATGACATAAACTTTCTTCACACGACCGCGGTCGATAAAGTCGTTCACATAGCTGCCGCCCCATGCAGCGCCCAGAGTGGTGTTAATGTCGTTGATAGAAACACCCAGCGCCTGCGCTTTTTCCTGGTCGATATCAATCTTAAACTGCGGGGTATCTTCCAGACCGTTTGGACGTACGCTGGTCAACATATCAGGGTGCTTCGCTGCTTCTGCAAGCAACTGGTTACGCGCCTGAGTCAGTTTTTCGTGACCAAGGCCAGCCTGGTCAATCAGCTCAAAGTCAAAGCCGGTTGCAGTACCCAGTTCCACGATTGCGGGCAGGTTAAAGGCGAAAACCATCGCATCTTTGATTTGCGAGAAAGCGCGTGTTGCACGCATGGTAATCGCTTCAACTTTGTTTTCTTCGCCCGGACGATCGGCCCAGTCCTTCAAGGAAACGAACGCAATACCGGTATTCTGACCACGTCCCGCAAAGCCGAAGCCGTTAACGGCGAACACCGACTCAACGTTGTTCTTTTCTTTGGTCAGATAGTAATGCGTTACCTCATTGAGCACTTTCTGTGTACGTTCCTGCGTTGCACCTGCTGGCAGCTGAACCATGGTCATAAACACGCCCTGGTCCTCATCTGGCAAGAAGGAGCTTGGCAGACGCACGAACAGATAGGCCATGCCGACCACGATGATCAGATACAGCACCAGGTAACGCCCCGTACTGCGCAGAATACCGCCTACGCTGTCGGTGTAGTGGTGCGTGCTCTTCTCGAACATGCGGTTAAACCAGCCGAAGAAGCCTTTTTTACCTTCCCCGTGATCGCCTTTGGCAATCGGTTTCAGCATGGTGGCACAAAGAGCTGGAGTCAGGATCAACGCCACCAGTACCGACAGCGCCATTGCTGAAACAATGGTAATAGAGAACTGACGATAGATAGCACCAGTAGAACCGCCAAAGAAGGCCATCGGTACGAATACCGCCGACAGTACCATCGCGATACCGACCAGAGCGCCCTGAATCTGCCCCATCGACTTACGGGTAGCTTCTTTTGGCGGCAAACCTTCTTCCGCCATAACACGCTCAACGTTTTCTACCACAACGATGGCGTCATCCACCAACAGGCCGATGGCGAGCACCATCCCGAACATTGTTAGCGTGTTTATCGAGAAGCCAAAGGCGGCAAGGACGGCAAAGGTCCCGAGCAATACCACCGGTACGGCAATGGTCGGAATCAACGTCGCGCGGAAGTTCTGCAGGAACAGATACATAACCAGGAACACGAGGATGATCGCTTCGACCAGCGTTTTAACCACTTCGTGAATAGAGATTTTCACGAACGGCGTGGTGTCGTATGGGTAAACAATTTTCAGACCCGACGGGAAGAACGGTTCCATCTTCGCCAGTTCAGCACGGATTGCCGCAGCGGTATCCAGCGCGTTTGCACCGGTCGCCAGCTTGATCCCCAGACCGGAAGCCGGTTGGCCGTTAAACTCTGCGATGATGTCGTAGTTCTCACCACCCAGCTCAATCTTCGCGACGTCACGCAGCAGCACGCGGGAACCATCCTGATTCACTTTCAGCAGGATTTTGCCGAACTCTTCAGTAGAGGTCAGACGCGTCTGAGCAATAATAGAGGCGTTAAGCTGTTGGCCTTTCACCGGCGGCGTACCACCGAGCTGACCCGCCGCAACCTGGGCGTTCTGCGCTTTGATGGCGGTAATGACATCAACCGGCGTTAGCTGGAATTTGTTCAGCTCATTCGGGTTCATCCAGATACGCATCGCGTACTGTGAACCGAACAACTGAACATCACCCACGCCCGACGTACGGCTGATGGCATCTTTCATATTCGCCGCCACGTAGTCGGAGATATCCTCCTGCGTCATGGTGCCATCGGTGTTGATAACGCCGACAACCATCAGGAAGCTGCTGGATGATTTCTCAACGCTCACCCCTTGCTGCTGAACTTCTTGCGGCAGCAACGGCATCGCCAGCTGCAGTTTGTTCTGCACCTGAACCTGCGCGATATCCGCATCAGTACCAGACTCAAAGGTCAGGGTGATCTGCACGGTACCCGTGGAGTCACTGTTAGAGGACATGTACATCAGGTTATCGATACCGTTCATATTCTGTTCGATAACCTGTGTCACCGTGTCCTGCACTGTTTTCGCATCAGCGCCGGGGTAGGAGGCGGAGATCGTTACTGCCGGCGGTGCAATCGTAGGATATTGCGCCACCGGCAGTTTGAGGATCGCCAGCCCCCCTGCCAACATGATGATAATGGCGATCACCCACGCAAAAATCGGGCGATCGATAAAGAAATTAGGCAT UPDATED NCBI_taxonomy_name with Escherichia coli str. K-12 substr. MG1655 UPDATED NCBI_taxonomy_id with 511145 UPDATED NCBI_taxonomy_cvterm_id with 36849 UPDATED GI with NP_414995.1 UPDATED sequence with MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRLTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNGLEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFSRKNEDIEHSHTVDHH " 2383 UPDATE ANT(4')-Ib antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1105 UPDATE AAC(3)-VIa antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2387 UPDATE Erm(47) antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 2386 UPDATE cipA determinant of phenicol resistance; determinant of macrolide resistance; determinant of linezolid resistance; antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; ARO_category; model_name "UPDATED category_aro_name with determinant of linezolid resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to linezolid antibiotics. UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of phenicol resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to phenicol (chloramphenicol) antibiotics. These include chloramphenicol acetyltransferase (CAT) enzymes, which are found in a large number of species. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. UPDATED model_name with cipA " 1102 UPDATE QnrB29 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1451 UPDATE MIR-17 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1100 UPDATE OXA-245 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1101 UPDATE CTX-M-21 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 902 UPDATE OXA-92 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 903 UPDATE APH(2'')-Ig antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1849 UPDATE Mycobacterium tuberculosis tlyA mutations conferring resistance to aminoglycosides antibiotic target modifying enzyme; antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category; model_param "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. UPDATED param_description with A parameter to describe the mapped insertion or deletion. For an insertion: insert the location and genetic sequence of the insertion. For a deletion: insert the location of the deletion. For nucleotide space: insertion: [nt][position]+[number of nucleotides]:[nucleotides] eg. nt312+1:G. For protein space: insertion: +[amino acids][start position:end position] eg. +S3:12. If both are known, a ""/"" may be used to separate the protein and nucleotide notation eg. nt312+3:AGC/+S312. " 901 UPDATE LCR-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 906 UPDATE CARB-21 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 904 UPDATE rmtB antibiotic target modifying enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 905 UPDATE CTX-M-93 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1843 UPDATE rmtD antibiotic target modifying enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1842 UPDATE IMI-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1841 UPDATE OXA-76 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1840 UPDATE CMY-59 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1846 UPDATE CTX-M-91 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1845 UPDATE OXA-312 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1844 UPDATE OXA-128 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2614 UPDATE mphD determinant of macrolide resistance; antibiotic inactivation enzyme; ARO_category; model_param "UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED param_value with 1e-140 UPDATED param_type_id with 36302 UPDATED param_type with BLASTP e-value UPDATED param_description with A curated expectation value (e-value) for assignment of an Antibiotic Resistance Ontology term based on a BLASTP hit to a CARD reference sequence. " 1908 UPDATE OKP-A-6 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1909 UPDATE AAC(6')-Iak antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1906 UPDATE CTX-M-17 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1907 UPDATE vanSA determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1904 UPDATE ACT-32 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1905 UPDATE ACT-21 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1902 UPDATE OXA-246 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1900 UPDATE ACT-13 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1901 UPDATE CTX-M-51 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 854 UPDATE CMY-58 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 855 UPDATE TEM-142 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 857 UPDATE nfxB efflux pump complex or subunit conferring antibiotic resistance; protein(s) and two-component regulatory system modulating antibiotic efflux; ARO_name; ARO_description; model_param; model_type; model_description; model_type_id "UPDATED ARO_name with NfxB UPDATED ARO_description with NfxB is a repressor of the efflux pump mexCD-oprJ and itself (NfxB binds upstream of the nfxB gene and negatively regulates its own expression). Increased expression of MexCD–OprJ brought about by mutations in NfxB. UPDATED 7539 with A124E UPDATED 7539 with A124E UPDATED param_type with single resistance variant UPDATED param_type_id with 36301 UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). UPDATED model_type with presence and absence of protein variant model UPDATED model_description with This model detects the presence and absence of mutations in protein space. This model reflects how certain proteins are functional with and without mutations. For example, efflux pump subunits and regulators are functional with mutations and without mutations. Without mutations, efflux pump subunits and regulators are usually expressed at a low level. When an efflux pump subunit has a mutation, it can cause the drug resistance profile of the efflux pump to change. When an efflux pump regulator has a mutation, it can cause the overexpression of the efflux pump it is responsible for regulating, leading to resistance to specific drugs. Thus, the goal is to be able to detect the presence and absence of mutations in efflux pump subunits and regulators to identify a functional efflux pump system, as well as, a mutated and functional efflux pump system. UPDATED model_type_id with 41091 " 850 UPDATE OXA-26 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 851 UPDATE Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide antibiotic resistant gene variant or mutant; determinant of pyrazinamide resistance; ARO_category; model_param "UPDATED category_aro_name with determinant of pyrazinamide resistance UPDATED param_description with A parameter to describe the mapped insertion or deletion. For an insertion: insert the location and genetic sequence of the insertion. For a deletion: insert the location of the deletion. For nucleotide space: insertion: [nt][position]+[number of nucleotides]:[nucleotides] eg. nt312+1:G. For protein space: insertion: +[amino acids][start position:end position] eg. +S3:12. If both are known, a ""/"" may be used to separate the protein and nucleotide notation eg. nt312+3:AGC/+S312. " 852 UPDATE QnrB62 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 853 UPDATE OXA-160 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 858 UPDATE IND-14 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 425 UPDATE TEM-182 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 740 UPDATE QnrB21 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 741 UPDATE CfxA antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 742 UPDATE AAC(3)-Id antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 743 UPDATE arr-3 determinant of rifamycin resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of rifamycin resistance UPDATED category_aro_description with Enzymes, other proteins, or other gene products shown clinically to confer resistance to rifamycin (rifampin) antibiotics. " 744 UPDATE vanSL determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 745 UPDATE CMY-40 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 746 UPDATE AAC(2')-Ib antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 747 UPDATE QnrA4 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 749 UPDATE SHV-97 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1050 UPDATE AAC(6')-Ii antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1051 UPDATE LEN-12 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1052 UPDATE OXA-206 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1053 UPDATE SHV-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1055 UPDATE Escherichia coli parE conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1056 UPDATE VIM-19 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1057 UPDATE CTX-M-114 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1058 UPDATE VIM-27 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1059 UPDATE APH(9)-Ib antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1696 UPDATE Salmonella serovars gyrB conferring resistance to fluoroquinolone antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1697 UPDATE TEM-135 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1694 UPDATE OXA-353 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1695 UPDATE DHA-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1692 UPDATE tetM antibiotic target protection protein; determinant of tetracycline resistance; ARO_category "UPDATED category_aro_name with determinant of tetracycline resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to tetracycline antibiotics or tetracycline-like derivatives. " 1693 UPDATE TEM-143 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1690 UPDATE OXA-317 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1691 UPDATE CMY-31 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 715 UPDATE PDC-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1698 UPDATE OCH-6 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1699 UPDATE vanXO determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1278 UPDATE TEM-45 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1279 UPDATE TEM-104 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 619 UPDATE SHV-30 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1270 UPDATE QnrS3 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 613 UPDATE VEB-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 610 UPDATE SHV-153 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 611 UPDATE OXA-328 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 616 UPDATE NDM-8 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 617 UPDATE OXA-147 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 614 UPDATE SFB-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 615 UPDATE OXA-211 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 711 UPDATE SHV-62 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 710 UPDATE dfrB6 antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 1472 UPDATE DHA-18 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1473 UPDATE CTX-M-44 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1470 UPDATE QnrB26 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1476 UPDATE TEM-199 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1477 UPDATE SHV-39 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1474 UPDATE mexR efflux pump complex or subunit conferring antibiotic resistance; antibiotic resistant gene variant or mutant; protein(s) and two-component regulatory system modulating antibiotic efflux; ARO_name; ARO_description; model_param; model_type; model_description; model_type_id "UPDATED ARO_name with MexR UPDATED ARO_description with MexR is the repressor of the MexRAB-OprM operon. Mutant forms of mexR result in up-regulation of efflux pump system MexAB-OprM. UPDATED 7614 with N53D UPDATED 7615 with H107P UPDATED 7614 with N53D UPDATED 7615 with H107P UPDATED model_type with presence and absence of protein variant model UPDATED model_description with This model detects the presence and absence of mutations in protein space. This model reflects how certain proteins are functional with and without mutations. For example, efflux pump subunits and regulators are functional with mutations and without mutations. Without mutations, efflux pump subunits and regulators are usually expressed at a low level. When an efflux pump subunit has a mutation, it can cause the drug resistance profile of the efflux pump to change. When an efflux pump regulator has a mutation, it can cause the overexpression of the efflux pump it is responsible for regulating, leading to resistance to specific drugs. Thus, the goal is to be able to detect the presence and absence of mutations in efflux pump subunits and regulators to identify a functional efflux pump system, as well as, a mutated and functional efflux pump system. UPDATED model_type_id with 41091 " 1475 UPDATE SHV-99 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1478 UPDATE CARB-10 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1479 UPDATE IMP-40 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1304 UPDATE CTX-M-85 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1305 UPDATE oprM efflux pump complex or subunit conferring antibiotic resistance; model_name; ARO_name "UPDATED model_name with OprM UPDATED ARO_name with OprM " 1306 UPDATE IND-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1307 UPDATE OXY-1-6 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1300 UPDATE mexF efflux pump complex or subunit conferring antibiotic resistance; model_name; ARO_name "UPDATED model_name with MexF UPDATED ARO_name with MexF " 1301 UPDATE Staphylococcus aureus cls conferring resistance to daptomycin antibiotic resistant gene variant or mutant; determinant of resistance to lipopeptide antibiotics; ARO_category "UPDATED category_aro_name with determinant of resistance to lipopeptide antibiotics " 1303 UPDATE BEL-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1308 UPDATE vanTE determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1309 UPDATE ACT-20 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 498 UPDATE QnrB17 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 499 UPDATE vanSB determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 494 UPDATE KPC-14 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 495 UPDATE CMY-28 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 496 UPDATE KPC-16 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 497 UPDATE OXA-79 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 490 UPDATE TEM-188 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 491 UPDATE PER-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 492 UPDATE catB determinant of phenicol resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of phenicol resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to phenicol (chloramphenicol) antibiotics. These include chloramphenicol acetyltransferase (CAT) enzymes, which are found in a large number of species. " 493 UPDATE TEM-84 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 24 UPDATE fusB antibiotic inactivation enzyme; determinant of fusidic acid resistance; ARO_category "UPDATED category_aro_name with determinant of fusidic acid resistance " 25 UPDATE CTX-M-121 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 26 UPDATE VEB-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 27 UPDATE lnuA determinant of lincosamide resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. " 20 UPDATE CMY-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 21 UPDATE OXA-329 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 22 UPDATE ACT-10 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 23 UPDATE OXA-371 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 28 UPDATE OXA-45 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 29 UPDATE Escherichia coli folP with mutation conferring resistance to sulfonamides antibiotic resistant gene variant or mutant; determinant of sulfonamide resistance; ARO_category; model_name "UPDATED category_aro_name with determinant of sulfonamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to sulfonamide antibiotics. UPDATED model_name with Escherichia coli folP with mutation conferring resistance to sulfonamides " 1516 UPDATE CMY-45 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1511 UPDATE OXA-423 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 7 UPDATE CTX-M-130 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2281 UPDATE Brucella suis mprF antibiotic target modifying enzyme; determinant of resistance to peptide antibiotics; ARO_category "UPDATED category_aro_name with determinant of resistance to peptide antibiotics " 2282 UPDATE Clostridium perfringens mprF antibiotic target modifying enzyme; determinant of resistance to peptide antibiotics; ARO_category "UPDATED category_aro_name with determinant of resistance to peptide antibiotics " 2283 UPDATE Streptococcus agalactiae mprF antibiotic target modifying enzyme; determinant of resistance to peptide antibiotics; ARO_category "UPDATED category_aro_name with determinant of resistance to peptide antibiotics " 2284 UPDATE Escherichia coli murA with mutation conferring resistance to fosfomycin determinant of fosfomycin resistance; antibiotic resistant gene variant or mutant; ARO_category; model_name "UPDATED category_aro_name with determinant of fosfomycin resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fosfomycin antibiotics. UPDATED category_aro_name with antibiotic resistant gene variant or mutant UPDATED category_aro_cvterm_id with 35950 UPDATED category_aro_accession with 0000031 UPDATED category_aro_description with Resistance to antibiotics is often conferred by single nucleotide polymorphisms (SNPs) and other mutations in target genes. UPDATED model_name with Escherichia coli murA with mutation conferring resistance to fosfomycin " 2375 UPDATE Rm3 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2372 UPDATE Escherichia coli GlpT with mutation conferring resistance to fosfomycin determinant of fosfomycin resistance; antibiotic resistant gene variant or mutant; ARO_category; model_name; model_param "UPDATED category_aro_name with determinant of fosfomycin resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fosfomycin antibiotics. UPDATED model_name with Escherichia coli GlpT with mutation conferring resistance to fosfomycin UPDATED param_description with A parameter to describe the mapped insertion or deletion. For an insertion: insert the location and genetic sequence of the insertion. For a deletion: insert the location of the deletion. For nucleotide space: insertion: [nt][position]+[number of nucleotides]:[nucleotides] eg. nt312+1:G. For protein space: insertion: +[amino acids][start position:end position] eg. +S3:12. If both are known, a ""/"" may be used to separate the protein and nucleotide notation eg. nt312+3:AGC/+S312. " 2373 UPDATE Escherichia coli UhpT with mutation conferring resistance to fosfomycin determinant of fosfomycin resistance; antibiotic resistant gene variant or mutant; ARO_category; model_name "UPDATED category_aro_name with determinant of fosfomycin resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fosfomycin antibiotics. UPDATED model_name with Escherichia coli UhpT with mutation conferring resistance to fosfomycin " 591 UPDATE CTX-M-122 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 590 UPDATE IND-6 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1876 UPDATE LEN-7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1877 UPDATE CMY-12 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1874 UPDATE OXA-196 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1875 UPDATE MIR-11 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1872 UPDATE vanXYL determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1873 UPDATE linG determinant of lincosamide resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. " 1870 UPDATE OXA-66 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1871 UPDATE OXA-389 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 595 UPDATE SHV-75 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1878 UPDATE SRT-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1879 UPDATE AAC(3)-IIIa antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 977 UPDATE OXA-112 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 976 UPDATE CTX-M-61 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 975 UPDATE QnrB1 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 973 UPDATE OXA-378 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 972 UPDATE CMY-23 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 970 UPDATE OKP-B-18 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 596 UPDATE ROB-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 979 UPDATE TEM-96 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 978 UPDATE OXA-134 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2119 UPDATE LRA-10 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 180 UPDATE DHA-19 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 181 UPDATE GES-14 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 186 UPDATE OXA-12 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 187 UPDATE OXA-348 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 184 UPDATE OCH-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 185 UPDATE OXA-232 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2110 UPDATE CARB-20 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2111 UPDATE Mycobacterium chelonae 16S rRNA mutation conferring resistance to tobramycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 188 UPDATE SHV-89 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2113 UPDATE Escherichia coli 16S rRNA (rrsB) mutation conferring resistance to tobramycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2114 UPDATE APH(3')-IIa antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2115 UPDATE TEM-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2116 UPDATE Pasteurella multocida 16S rRNA mutation conferring resistance to spectinomycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2117 UPDATE AAC(6')-Ib7 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1919 UPDATE SHV-27 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1918 UPDATE spd antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1911 UPDATE AAC(6')-Iad antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1910 UPDATE CTX-M-136 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1913 UPDATE dfrK antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 1912 UPDATE LRA-13 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1915 UPDATE CMY-47 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1914 UPDATE BEL-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1917 UPDATE tet(30) efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with tet(30) " 1916 UPDATE TEM-208 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 868 UPDATE DHA-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 189 UPDATE CTX-M-19 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 861 UPDATE OXA-215 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 860 UPDATE TEM-42 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 863 UPDATE PER-7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 862 UPDATE IMP-16 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 865 UPDATE OXA-244 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 864 UPDATE CMY-61 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 867 UPDATE OXA-175 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2024 UPDATE ACC-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2025 UPDATE TEM-57 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2026 UPDATE OXA-84 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2027 UPDATE CMY-84 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2020 UPDATE tetO antibiotic target protection protein; determinant of tetracycline resistance; ARO_category "UPDATED category_aro_name with determinant of tetracycline resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to tetracycline antibiotics or tetracycline-like derivatives. " 2021 UPDATE SHV-165 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2022 UPDATE CTX-M-104 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2023 UPDATE OXA-132 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2028 UPDATE QnrB43 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 2029 UPDATE TEM-123 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 656 UPDATE OXA-219 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 883 UPDATE LRA-17 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 882 UPDATE NPS beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 881 UPDATE ErmC antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 880 UPDATE APH(6)-Ib antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 887 UPDATE SHV-33 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 886 UPDATE IND-10 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 885 UPDATE TEM-63 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 884 UPDATE CTX-M-99 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 889 UPDATE CMY-74 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 888 UPDATE Erm(36) antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 775 UPDATE CMY-113 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 774 UPDATE tet37 antibiotic inactivation enzyme; determinant of tetracycline resistance; ARO_category "UPDATED category_aro_name with determinant of tetracycline resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to tetracycline antibiotics or tetracycline-like derivatives. " 776 UPDATE tetX antibiotic inactivation enzyme; determinant of tetracycline resistance; ARO_category "UPDATED category_aro_name with determinant of tetracycline resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to tetracycline antibiotics or tetracycline-like derivatives. " 771 UPDATE CMY-24 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 770 UPDATE SHV-57 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 773 UPDATE OCH-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 772 UPDATE LEN-6 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 779 UPDATE OXA-350 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 778 UPDATE IMP-25 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 77 UPDATE TEM-47 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 76 UPDATE SHV-79 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 75 UPDATE fusH antibiotic inactivation enzyme; determinant of fusidic acid resistance; ARO_category "UPDATED category_aro_name with determinant of fusidic acid resistance " 74 UPDATE SHV-18 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 73 UPDATE OXA-35 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 72 UPDATE SHV-42 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 71 UPDATE QnrB66 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 70 UPDATE NDM-10 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 79 UPDATE VIM-37 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 78 UPDATE TEM-16 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1043 UPDATE SHV-76 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1042 UPDATE catB7 determinant of phenicol resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of phenicol resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to phenicol (chloramphenicol) antibiotics. These include chloramphenicol acetyltransferase (CAT) enzymes, which are found in a large number of species. " 1041 UPDATE mexS efflux pump complex or subunit conferring antibiotic resistance; protein(s) and two-component regulatory system modulating antibiotic efflux; ARO_name; model_param; model_type; model_description; model_name; model_type_id "UPDATED ARO_name with MexS UPDATED 7573 with V104A UPDATED 7575 with D44E UPDATED 7574 with F253L UPDATED 7577 with F185L UPDATED 7576 with S60F UPDATED 7579 with L270Q UPDATED 7578 with V73A UPDATED 7580 with C245G UPDATED 7581 with A166P UPDATED 7582 with S60P UPDATED 7583 with L263Q UPDATED 7573 with V104A UPDATED 7575 with D44E UPDATED 7574 with F253L UPDATED 7577 with F185L UPDATED 7576 with S60F UPDATED 7579 with L270Q UPDATED 7578 with V73A UPDATED 7580 with C245G UPDATED 7581 with A166P UPDATED 7582 with S60P UPDATED 7583 with L263Q UPDATED param_type with single resistance variant UPDATED param_type_id with 36301 UPDATED param_description with A mutation or sequence variant that confers elevated resistance to antibiotic(s) relative to wild type. The most common encoded in the CARD is an amino acid substitution gleaned from the literature with format [wild-type][position][mutation], e.g. R184Q. Single or multiple amino acid substitutions can be present in a single gene or across multiple genes to confer resistance to antibiotic(s). In addition, there are insertions and deletions within genome sequences that confer elevated resistance towards antibiotic(s). UPDATED model_type with presence and absence of protein variant model UPDATED model_description with This model detects the presence and absence of mutations in protein space. This model reflects how certain proteins are functional with and without mutations. For example, efflux pump subunits and regulators are functional with mutations and without mutations. Without mutations, efflux pump subunits and regulators are usually expressed at a low level. When an efflux pump subunit has a mutation, it can cause the drug resistance profile of the efflux pump to change. When an efflux pump regulator has a mutation, it can cause the overexpression of the efflux pump it is responsible for regulating, leading to resistance to specific drugs. Thus, the goal is to be able to detect the presence and absence of mutations in efflux pump subunits and regulators to identify a functional efflux pump system, as well as, a mutated and functional efflux pump system. UPDATED model_name with MexS UPDATED model_type_id with 41091 " 1040 UPDATE OXA-95 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1047 UPDATE catS determinant of phenicol resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of phenicol resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to phenicol (chloramphenicol) antibiotics. These include chloramphenicol acetyltransferase (CAT) enzymes, which are found in a large number of species. " 1045 UPDATE ErmO antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 1044 UPDATE CTX-M-22 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1049 UPDATE MOX-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1048 UPDATE QnrB33 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1681 UPDATE APH(4)-Ib antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1683 UPDATE QnrB67 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1682 UPDATE aadA24 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1685 UPDATE SHV-40 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1684 UPDATE LEN-18 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1687 UPDATE CEPH-A3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1686 UPDATE OXA-34 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1689 UPDATE vanRO determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1688 UPDATE CTX-M-90 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1269 UPDATE OXA-192 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1268 UPDATE CMY-115 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 669 UPDATE MIR-12 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 668 UPDATE CTX-M-65 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 667 UPDATE ACT-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1262 UPDATE SHV-149 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 665 UPDATE TEM-10 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 664 UPDATE CMY-43 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1267 UPDATE QnrB40 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1266 UPDATE ANT(4')-IIa antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1265 UPDATE MIR-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 660 UPDATE Streptococcus pneumoniae parC conferring resistance to fluoroquinolone gene involved in self-resistance to antibiotic; antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category; model_name "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics UPDATED model_name with Streptococcus pneumoniae parC conferring resistance to fluoroquinolone " 1469 UPDATE facT efflux pump complex or subunit conferring antibiotic resistance; determinant of elfamycin resistance; ARO_category "UPDATED category_aro_name with determinant of elfamycin resistance " 1468 UPDATE SHV-135 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1465 UPDATE SHV-181 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1464 UPDATE aadA7 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1467 UPDATE LEN-22 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1466 UPDATE SHV-13 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1461 UPDATE SHV-63 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1460 UPDATE FosB3 antibiotic inactivation enzyme; determinant of fosfomycin resistance; ARO_category "UPDATED category_aro_name with determinant of fosfomycin resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fosfomycin antibiotics. " 1463 UPDATE GES-19 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1019 UPDATE IMP-21 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1317 UPDATE CTX-M-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1316 UPDATE catB6 determinant of phenicol resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of phenicol resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to phenicol (chloramphenicol) antibiotics. These include chloramphenicol acetyltransferase (CAT) enzymes, which are found in a large number of species. " 1314 UPDATE OXA-214 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1312 UPDATE OXA-111 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1311 UPDATE OXY-5-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1310 UPDATE IMP-10 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1319 UPDATE SHV-147 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1010 UPDATE TEM-209 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1011 UPDATE TEM-29 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 319 UPDATE OXA-366 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 318 UPDATE OXA-358 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 313 UPDATE OXA-143 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 312 UPDATE OXA-167 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 311 UPDATE IND-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 310 UPDATE SHV-78 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 317 UPDATE TEM-148 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 316 UPDATE CTX-M-36 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 315 UPDATE DHA-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 314 UPDATE TEM-176 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 443 UPDATE OKP-B-10 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 442 UPDATE opmD efflux pump complex or subunit conferring antibiotic resistance; ARO_name "UPDATED ARO_name with OpmD " 440 UPDATE mexA efflux pump complex or subunit conferring antibiotic resistance; model_name; ARO_name "UPDATED model_name with MexA UPDATED ARO_name with MexA " 447 UPDATE SHV-67 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 446 UPDATE catB8 determinant of phenicol resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of phenicol resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to phenicol (chloramphenicol) antibiotics. These include chloramphenicol acetyltransferase (CAT) enzymes, which are found in a large number of species. " 445 UPDATE TEM-22 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 444 UPDATE AAC(6')-Ib-Suzhou antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2298 UPDATE SPM-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2292 UPDATE Streptomyces rishiriensis parY mutant conferring resistance to aminocoumarin determinant of aminocoumarin resistance; gene involved in self-resistance to antibiotic; antibiotic resistant gene variant or mutant; ARO_category "UPDATED category_aro_name with determinant of aminocoumarin resistance " 2291 UPDATE Chlamydia trachomatis intrinsic murA conferring resistance to fosfomycin determinant of fosfomycin resistance; antibiotic resistant gene variant or mutant; ARO_category; model_name "UPDATED category_aro_name with determinant of fosfomycin resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fosfomycin antibiotics. UPDATED category_aro_name with antibiotic resistant gene variant or mutant UPDATED category_aro_cvterm_id with 35950 UPDATED category_aro_accession with 0000031 UPDATED category_aro_description with Resistance to antibiotics is often conferred by single nucleotide polymorphisms (SNPs) and other mutations in target genes. UPDATED model_name with Chlamydia trachomatis intrinsic murA conferring resistance to fosfomycin " 2290 UPDATE Mycobacterium tuberculosis intrinsic murA conferring resistance to fosfomycin determinant of fosfomycin resistance; antibiotic resistant gene variant or mutant; ARO_category; model_name "UPDATED category_aro_name with determinant of fosfomycin resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fosfomycin antibiotics. UPDATED category_aro_name with antibiotic resistant gene variant or mutant UPDATED category_aro_cvterm_id with 35950 UPDATED category_aro_accession with 0000031 UPDATED category_aro_description with Resistance to antibiotics is often conferred by single nucleotide polymorphisms (SNPs) and other mutations in target genes. UPDATED model_name with Mycobacterium tuberculosis intrinsic murA conferring resistance to fosfomycin " 2294 UPDATE Campylobacter jejuni gyrA conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category; model_name "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics UPDATED model_name with Campylobacter jejuni gyrA conferring resistance to fluoroquinolones " 1712 UPDATE IMP-41 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1861 UPDATE LEN-15 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1860 UPDATE OXA-165 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1863 UPDATE VIM-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1862 UPDATE OXA-109 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1865 UPDATE ACC-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1864 UPDATE CMY-67 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1867 UPDATE CTX-M-116 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1866 UPDATE KPC-7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1869 UPDATE OXY-2-6 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1868 UPDATE TEM-82 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 964 UPDATE OXA-129 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 965 UPDATE OXA-333 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 966 UPDATE vanSC determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 967 UPDATE AAC(6')-Isa antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 960 UPDATE TEM-137 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 961 UPDATE SHV-93 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 962 UPDATE OXA-356 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 963 UPDATE CMY-69 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 968 UPDATE MIR-15 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 969 UPDATE VEB-8 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2109 UPDATE Mycobacterium tuberculosis gyrB mutant conferring resistance to fluoroquinolone antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 2108 UPDATE Enterococcus faecium EF-Tu mutants conferring resistance to GE2270A antibiotic resistant gene variant or mutant; determinant of elfamycin resistance; ARO_category; model_name "UPDATED category_aro_name with determinant of elfamycin resistance UPDATED model_name with Enterococcus faecium EF-Tu mutants conferring resistance to GE2270A " 2103 UPDATE SHV-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2102 UPDATE Mycobacterium smegmatis 16S rRNA (rrsB) mutation conferring resistance to hygromycin B antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2100 UPDATE Mycobacterium chelonae 16S rRNA mutation conferring resistance to amikacin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2106 UPDATE Mycobacterium smegmatis 16S rRNA (rrsA) mutation conferring resistance to kanamycin A antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2105 UPDATE Mycobacterium abscessus 16S rRNA mutation conferring resistance to neomycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2104 UPDATE Ureaplasma urealyticum parC conferring resistance to fluoroquinolone gene involved in self-resistance to antibiotic; antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 635 UPDATE OXA-332 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 641 UPDATE CARB-6 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 878 UPDATE CTX-M-142 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 640 UPDATE tet(31) efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with tet(31) " 877 UPDATE SHV-124 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 874 UPDATE AAC(1) antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 875 UPDATE dfrA19 antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 872 UPDATE vatC antibiotic inactivation enzyme; determinant of streptogramin resistance; ARO_category "UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 873 UPDATE KPC-19 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 870 UPDATE otr(B) efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with otr(B) " 871 UPDATE CGB-1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2037 UPDATE tetT antibiotic target protection protein; determinant of tetracycline resistance; ARO_category "UPDATED category_aro_name with determinant of tetracycline resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to tetracycline antibiotics or tetracycline-like derivatives. " 2036 UPDATE SHV-163 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2035 UPDATE CTX-M-15 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1242 UPDATE aadA6/aadA10 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2032 UPDATE CTX-M-62 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2031 UPDATE OXA-173 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2030 UPDATE AAC(3)-IXa antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 9 UPDATE ACT-35 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 645 UPDATE mecR1 antibiotic resistance gene cluster, cassette, or operon; antibiotic target replacement protein; determinant of beta-lactam resistance; gene modulating beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2039 UPDATE CARB-18 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2038 UPDATE KPC-17 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 890 UPDATE SHV-53 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 891 UPDATE QnrB37 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 892 UPDATE APH(6)-Ic antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 893 UPDATE linA determinant of lincosamide resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. " 894 UPDATE CMY-90 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 895 UPDATE SHV-122 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 896 UPDATE CTX-M-131 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 897 UPDATE OXA-383 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 898 UPDATE VEB-9 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 899 UPDATE OXA-94 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 646 UPDATE OXA-349 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 649 UPDATE OXA-115 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1537 UPDATE GES-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1964 UPDATE IMP-45 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1965 UPDATE LEN-11 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1788 UPDATE ACT-6 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1789 UPDATE QnrB44 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 768 UPDATE SHV-43 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1967 UPDATE OXA-116 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1780 UPDATE OXA-146 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1781 UPDATE AAC(2')-Ia antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1782 UPDATE TEM-12 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1783 UPDATE VIM-36 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1784 UPDATE OXA-334 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1785 UPDATE TEM-48 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1786 UPDATE mexY efflux pump complex or subunit conferring antibiotic resistance; ARO_name "UPDATED ARO_name with MexY " 1787 UPDATE VIM-42 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1962 UPDATE OXA-47 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1963 UPDATE TEM-190 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1078 UPDATE VIM-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1079 UPDATE OXA-161 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1076 UPDATE IMP-37 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 643 UPDATE OXY-2-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1074 UPDATE LEN-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1075 UPDATE TEM-20 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1072 UPDATE OXA-37 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1073 UPDATE OKP-B-19 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1070 UPDATE sul1 antibiotic target replacement protein; determinant of sulfonamide resistance; ARO_category "UPDATED category_aro_name with determinant of sulfonamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to sulfonamide antibiotics. " 1071 UPDATE DHA-22 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1678 UPDATE AAC(6')-Ib-cr antibiotic inactivation enzyme; determinant of aminoglycoside resistance; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1679 UPDATE OXA-49 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1674 UPDATE AAC(6')-It antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1675 UPDATE CTX-M-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1676 UPDATE GES-18 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1677 UPDATE cepA beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1670 UPDATE nalC efflux pump complex or subunit conferring antibiotic resistance; protein(s) and two-component regulatory system modulating antibiotic efflux; model_type; model_description; model_param; model_type_id "UPDATED model_type with presence and absence of protein variant model UPDATED model_description with This model detects the presence and absence of mutations in protein space. This model reflects how certain proteins are functional with and without mutations. For example, efflux pump subunits and regulators are functional with mutations and without mutations. Without mutations, efflux pump subunits and regulators are usually expressed at a low level. When an efflux pump subunit has a mutation, it can cause the drug resistance profile of the efflux pump to change. When an efflux pump regulator has a mutation, it can cause the overexpression of the efflux pump it is responsible for regulating, leading to resistance to specific drugs. Thus, the goal is to be able to detect the presence and absence of mutations in efflux pump subunits and regulators to identify a functional efflux pump system, as well as, a mutated and functional efflux pump system. UPDATED 7533 with G71E UPDATED 7533 with G71E UPDATED model_type_id with 41091 " 1671 UPDATE Salmonella serovars soxS mutants efflux pump complex or subunit conferring antibiotic resistance; antibiotic resistant gene variant or mutant; protein modulating permeability to antibiotic; protein(s) and two-component regulatory system modulating antibiotic efflux; model_name; ARO_name "UPDATED model_name with Salmonella serovars soxS with mutation conferring antibiotic resistance UPDATED ARO_name with Salmonella serovars soxS with mutation conferring antibiotic resistance " 1672 UPDATE TEM-211 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1673 UPDATE QnrA6 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1094 UPDATE CARB-17 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1095 UPDATE SHV-59 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1096 UPDATE TEM-79 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1097 UPDATE Erm(38) antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 678 UPDATE PDC-10 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 679 UPDATE SHV-108 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1092 UPDATE tet(39) efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with tet(39) " 1093 UPDATE AAC(6')-31 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 674 UPDATE OXA-15 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 675 UPDATE OXA-25 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 676 UPDATE AAC(6')-Ih antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 677 UPDATE OXA-171 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 670 UPDATE IND-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 671 UPDATE CTX-M-137 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 672 UPDATE CMY-27 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 673 UPDATE IMP-48 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1533 UPDATE SHV-143 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1418 UPDATE DHA-6 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1419 UPDATE OXA-454 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1410 UPDATE OXA-19 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1411 UPDATE OXA-62 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1412 UPDATE SHV-167 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1413 UPDATE OXA-172 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1414 UPDATE QnrB15 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1415 UPDATE AAC(2')-Id antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1416 UPDATE OXA-89 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1417 UPDATE OXA-131 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1322 UPDATE SHV-65 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1323 UPDATE Salmonella serovars parE conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1320 UPDATE Klebsiella mutant PhoP conferring antibiotic resistance to colistin efflux pump complex or subunit conferring antibiotic resistance; determinant of polymyxin resistance; antibiotic resistant gene variant or mutant; protein(s) and two-component regulatory system modulating antibiotic efflux; gene altering cell wall charge; ARO_category "UPDATED category_aro_name with determinant of polymyxin resistance " 644 UPDATE OXY-2-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1326 UPDATE OXA-170 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1327 UPDATE AAC(6')-Iq antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1324 UPDATE LRA-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1325 UPDATE OXA-65 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1328 UPDATE vanSM determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1329 UPDATE ANT(4')-IIb antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1531 UPDATE TEM-81 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1524 UPDATE cat-TC determinant of phenicol resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of phenicol resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to phenicol (chloramphenicol) antibiotics. These include chloramphenicol acetyltransferase (CAT) enzymes, which are found in a large number of species. " 1525 UPDATE TEM-160 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1254 UPDATE CTX-M-46 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1527 UPDATE SHV-51 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1520 UPDATE SHV-85 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1521 UPDATE VIM-32 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1522 UPDATE IMP-38 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1523 UPDATE mexD efflux pump complex or subunit conferring antibiotic resistance; model_name; ARO_name "UPDATED model_name with MexD UPDATED ARO_name with MexD " 1528 UPDATE TEM-168 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1529 UPDATE TEM-130 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1258 UPDATE OXA-55 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1259 UPDATE SHV-31 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 308 UPDATE CMY-118 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 309 UPDATE CMY-35 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 300 UPDATE AAC(6')-29a antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 301 UPDATE CMY-95 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 302 UPDATE TEM-207 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 303 UPDATE ErmQ antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 304 UPDATE IND-11 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 305 UPDATE chrB antibiotic target modifying enzyme; gene involved in self-resistance to antibiotic; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. " 306 UPDATE SHV-32 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 307 UPDATE CTX-M-101 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " _timestamp N/A N/A N/A N/A NEW: 2017-04-05T18:43:39+00:00 , OLD: 2017-03-06T15:41:51+00:00 985 UPDATE ErmA antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 114 UPDATE dfrA13 antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 1898 UPDATE OXA-379 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1899 UPDATE vanYF determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1895 UPDATE CfxA3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1896 UPDATE NDM-12 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1897 UPDATE tet(L) efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with tet(L) " 1890 UPDATE TEM-86 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1891 UPDATE AAC(6')-Iih antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1892 UPDATE OXA-114a antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1893 UPDATE SHV-127 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2136 UPDATE Escherichia coli 16S rRNA (rrsB) mutation conferring resistance to kanamycin A antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2137 UPDATE Escherichia coli EF-Tu mutants conferring resistance to kirromycin antibiotic resistant gene variant or mutant; determinant of elfamycin resistance; ARO_category "UPDATED category_aro_name with determinant of elfamycin resistance " 2134 UPDATE CMY-36 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2135 UPDATE ACT-33 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2132 UPDATE Mycobacterium tuberculosis 16S rRNA mutation conferring resistance to kanamycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2133 UPDATE Mycobacterium tuberculosis 16S rRNA mutation conferring resistance to viomycin determinant of resistance to peptide antibiotics; antibiotic resistant gene variant or mutant; ARO_category "UPDATED category_aro_name with determinant of resistance to peptide antibiotics " 2131 UPDATE Mycobacterium tuberculosis 16S rRNA mutation conferring resistance to streptomycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 951 UPDATE ACT-15 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 950 UPDATE ErmX antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 952 UPDATE sul2 antibiotic target replacement protein; determinant of sulfonamide resistance; ARO_category "UPDATED category_aro_name with determinant of sulfonamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to sulfonamide antibiotics. " 955 UPDATE SHV-96 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 954 UPDATE APH(3')-IIb antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2138 UPDATE NmcA beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2139 UPDATE vanSD determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 2002 UPDATE cat86 determinant of phenicol resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of phenicol resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to phenicol (chloramphenicol) antibiotics. These include chloramphenicol acetyltransferase (CAT) enzymes, which are found in a large number of species. " 2003 UPDATE pmrA efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with pmrA " 2000 UPDATE TEM-24 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2001 UPDATE OXA-250 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2006 UPDATE IMP-27 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2007 UPDATE OXA-335 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2004 UPDATE TEM-189 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2005 UPDATE CTX-M-89 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2008 UPDATE SHV-145 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2009 UPDATE aadA6 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1263 UPDATE QnrB56 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 666 UPDATE CTX-M-34 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1799 UPDATE TEM-147 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1798 UPDATE SHV-183 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 719 UPDATE CMY-33 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 718 UPDATE LRA-8 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 717 UPDATE CTX-M-100 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1792 UPDATE DHA-20 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1791 UPDATE TEM-164 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 714 UPDATE dfrB1 antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 713 UPDATE CTX-M-81 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 712 UPDATE catB2 determinant of phenicol resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of phenicol resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to phenicol (chloramphenicol) antibiotics. These include chloramphenicol acetyltransferase (CAT) enzymes, which are found in a large number of species. " 1795 UPDATE VEB-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1794 UPDATE tmrB determinant of resistance to nucleoside antibiotics; protein modulating permeability to antibiotic; ARO_category "UPDATED category_aro_name with determinant of resistance to nucleoside antibiotics " 661 UPDATE VIM-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 716 UPDATE QnrB32 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 505 UPDATE Mycobacterium tuberculosis iniC mutant conferring resistance to ethambutol efflux pump complex or subunit conferring antibiotic resistance; antibiotic resistant gene variant or mutant; determinant of resistance to polyamine antibiotics; ARO_category; model_param "UPDATED category_aro_name with determinant of resistance to polyamine antibiotics UPDATED param_description with A parameter to describe the mapped insertion or deletion. For an insertion: insert the location and genetic sequence of the insertion. For a deletion: insert the location of the deletion. For nucleotide space: insertion: [nt][position]+[number of nucleotides]:[nucleotides] eg. nt312+1:G. For protein space: insertion: +[amino acids][start position:end position] eg. +S3:12. If both are known, a ""/"" may be used to separate the protein and nucleotide notation eg. nt312+3:AGC/+S312. " 1069 UPDATE IMP-35 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1068 UPDATE AAC(6')-Ib3 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1061 UPDATE OXY-2-10 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1060 UPDATE SHV-103 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1063 UPDATE QnrB73 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1062 UPDATE SHV-71 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1065 UPDATE OXA-384 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1064 UPDATE CTX-M-141 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1067 UPDATE mexE efflux pump complex or subunit conferring antibiotic resistance; model_name; ARO_name "UPDATED model_name with MexE UPDATED ARO_name with MexE " 1066 UPDATE TEM-118 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1669 UPDATE vanZF determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1668 UPDATE CMY-68 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1667 UPDATE TEM-80 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1666 UPDATE vanXB determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1663 UPDATE ACC-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1662 UPDATE OKP-B-17 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1661 UPDATE CARB-8 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1660 UPDATE OXA-375 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1087 UPDATE OXA-253 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1086 UPDATE CMY-41 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1085 UPDATE OKP-B-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1084 UPDATE LEN-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1083 UPDATE OXA-323 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 594 UPDATE QnrB41 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1081 UPDATE IMP-30 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1080 UPDATE SHV-158 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 599 UPDATE OKP-A-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 598 UPDATE dfrA16 antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 1089 UPDATE CMY-14 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1088 UPDATE Staphylococcus aureus rpoB mutants conferring resistance to daptomycin antibiotic resistant gene variant or mutant; determinant of resistance to lipopeptide antibiotics; ARO_category "UPDATED category_aro_name with determinant of resistance to lipopeptide antibiotics " 1526 UPDATE AAC(6')-Iaa antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1409 UPDATE CMY-6 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1408 UPDATE TEM-124 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1403 UPDATE OXA-388 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1402 UPDATE OXA-390 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1400 UPDATE CTX-M-74 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1407 UPDATE CMY-62 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1406 UPDATE OXA-121 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1405 UPDATE armA antibiotic target modifying enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1404 UPDATE IMP-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1546 UPDATE Erm(43) antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 449 UPDATE SHV-133 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 448 UPDATE dfrG antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 1339 UPDATE Mycobacterium tuberculosis embR mutant conferring resistance to ethambutol antibiotic resistant gene variant or mutant; determinant of resistance to polyamine antibiotics; ARO_category "UPDATED category_aro_name with determinant of resistance to polyamine antibiotics " 1338 UPDATE BLA1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1547 UPDATE vanRC determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1335 UPDATE QnrB8 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1334 UPDATE SHV-126 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 441 UPDATE OXA-54 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1336 UPDATE BcII antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1331 UPDATE CTX-M-52 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 690 UPDATE OXA-347 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1333 UPDATE vanHD determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1332 UPDATE APH(3')-IIIa antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1545 UPDATE Escherichia coli gyrA conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1631 UPDATE CTX-M-71 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1543 UPDATE CMY-22 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 39 UPDATE AAC(3)-Ia antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 38 UPDATE APH(3')-Va antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1540 UPDATE rmtC antibiotic target modifying enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 32 UPDATE DHA-15 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 31 UPDATE CTX-M-155 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 30 UPDATE OXA-226 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 36 UPDATE Mycobaterium leprae gyrA conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 35 UPDATE FosA2 antibiotic inactivation enzyme; determinant of fosfomycin resistance; ARO_category "UPDATED category_aro_name with determinant of fosfomycin resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fosfomycin antibiotics. " 34 UPDATE OXY-6-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1241 UPDATE TEM-144 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1536 UPDATE OXA-421 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1535 UPDATE CMY-16 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1534 UPDATE PER-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1245 UPDATE TEM-114 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1532 UPDATE OXA-249 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1247 UPDATE CMY-72 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1530 UPDATE OXA-67 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1249 UPDATE FOX-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 648 UPDATE GES-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1539 UPDATE aadA3 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1538 UPDATE SHV-104 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 339 UPDATE ANT(3'')-Ii-AAC(6')-IId fusion protein antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 338 UPDATE OXY-1-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 335 UPDATE Staphylococcus aureus parE conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 334 UPDATE mexX efflux pump complex or subunit conferring antibiotic resistance; ARO_name "UPDATED ARO_name with MexX " 337 UPDATE adeC efflux pump complex or subunit conferring antibiotic resistance; model_param "UPDATED param_value with 850 UPDATED param_value with 1e-120 UPDATED param_type_id with 36302 UPDATED param_type with BLASTP e-value UPDATED param_description with A curated expectation value (e-value) for assignment of an Antibiotic Resistance Ontology term based on a BLASTP hit to a CARD reference sequence. " 336 UPDATE tlrB conferring tylosin resistance antibiotic target modifying enzyme; gene involved in self-resistance to antibiotic; determinant of macrolide resistance; ARO_category; model_name "UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED model_name with tlrB conferring tylosin resistance " 331 UPDATE TEM-166 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 330 UPDATE IMP-26 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 333 UPDATE CARB-23 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 332 UPDATE r39 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 8 UPDATE NDM-6 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1353 UPDATE GES-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1636 UPDATE QnrB57 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1462 UPDATE LRA-19 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1352 UPDATE OXA-251 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1889 UPDATE NDM-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1888 UPDATE MIR-10 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1887 UPDATE TEM-70 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1886 UPDATE LEN-24 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1885 UPDATE tet(Z) efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with tet(Z) " 1884 UPDATE CTX-M-111 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1883 UPDATE DHA-10 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1882 UPDATE OXA-80 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1881 UPDATE OXA-72 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2121 UPDATE LRA-7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2122 UPDATE Mycobacterium chelonae 16S rRNA mutation conferring resistance to neomycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2124 UPDATE Clostridium difficile EF-Tu mutants conferring resistance to elfamycin antibiotic resistant gene variant or mutant; determinant of elfamycin resistance; ARO_category "UPDATED category_aro_name with determinant of elfamycin resistance " 948 UPDATE mecI antibiotic resistance gene cluster, cassette, or operon; antibiotic target replacement protein; determinant of beta-lactam resistance; gene modulating beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 949 UPDATE CTX-M-77 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 946 UPDATE QnrB48 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 947 UPDATE OXA-100 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 945 UPDATE tet(40) efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with tet(40) " 942 UPDATE OXA-104 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 943 UPDATE vanU determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 940 UPDATE TEM-125 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 941 UPDATE GES-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2410 UPDATE Salmonella enterica parC conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 133 UPDATE arr-8 determinant of rifamycin resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of rifamycin resistance UPDATED category_aro_description with Enzymes, other proteins, or other gene products shown clinically to confer resistance to rifamycin (rifampin) antibiotics. " 132 UPDATE TEM-198 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 131 UPDATE CTX-M-50 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 130 UPDATE CTX-M-112 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 137 UPDATE APH(2'')-Ie antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 136 UPDATE CMY-9 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 135 UPDATE SME-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 134 UPDATE rgt1438 determinant of rifamycin resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of rifamycin resistance UPDATED category_aro_description with Enzymes, other proteins, or other gene products shown clinically to confer resistance to rifamycin (rifampin) antibiotics. " 139 UPDATE QnrB10 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1354 UPDATE Mycobacterium tuberculosis embA mutant conferring resistance to ethambutol antibiotic resistant gene variant or mutant; determinant of resistance to polyamine antibiotics; ARO_category "UPDATED category_aro_name with determinant of resistance to polyamine antibiotics " 2019 UPDATE OXA-213 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2018 UPDATE CMY-76 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2015 UPDATE DHA-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2014 UPDATE PmrF determinant of polymyxin resistance; gene altering cell wall charge; ARO_category "UPDATED category_aro_name with determinant of polymyxin resistance " 2017 UPDATE CTX-M-37 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2016 UPDATE OXA-370 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2011 UPDATE QnrB60 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 2010 UPDATE CTX-M-129 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2013 UPDATE Erm(41) antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 2012 UPDATE SHV-178 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 708 UPDATE CTX-M-49 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 709 UPDATE TEM-213 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 704 UPDATE oprJ efflux pump complex or subunit conferring antibiotic resistance; model_name; ARO_name "UPDATED model_name with OprJ UPDATED ARO_name with OprJ " 705 UPDATE CMY-116 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 706 UPDATE APH(7'')-Ia antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 707 UPDATE AIM-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 700 UPDATE ACT-31 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 701 UPDATE SHV-129 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 702 UPDATE CTX-M-98 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 703 UPDATE cmlv determinant of phenicol resistance; antibiotic inactivation enzyme; ARO_category; model_param "UPDATED category_aro_name with determinant of phenicol resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to phenicol (chloramphenicol) antibiotics. These include chloramphenicol acetyltransferase (CAT) enzymes, which are found in a large number of species. UPDATED param_value with 700 UPDATED param_type_id with 40725 UPDATED param_type with BLASTP bit-score UPDATED param_description with A score is a numerical value that describes the overall quality of an alignment. Higher numbers correspond to higher similarity. The bit-score (S) is determined by the following formula: S = (λ × S − lnK)/ ln2 where λ is the Gumble distribution constant, S is the raw alignment score, and K is a constant associated with the scoring matrix. " 88 UPDATE CMY-55 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 89 UPDATE vanYA determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 82 UPDATE PER-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 83 UPDATE IMP-47 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 80 UPDATE ACT-29 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 81 UPDATE FOX-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 86 UPDATE TEM-102 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 87 UPDATE TEM-116 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 84 UPDATE GIM-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 85 UPDATE IMP-42 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 762 UPDATE CTX-M-55 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1658 UPDATE OKP-B-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1659 UPDATE OXA-258 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1652 UPDATE IMP-20 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1653 UPDATE AAC(6')-Ip antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1650 UPDATE CMY-15 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1651 UPDATE AAC(6')-If antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1656 UPDATE CTX-M-79 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1657 UPDATE AAC(6')-IIa antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1654 UPDATE SHV-95 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1655 UPDATE TEM-117 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 586 UPDATE VIM-20 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 587 UPDATE TEM-73 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 584 UPDATE aadA21 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 585 UPDATE NDM-7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 763 UPDATE catI determinant of phenicol resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of phenicol resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to phenicol (chloramphenicol) antibiotics. These include chloramphenicol acetyltransferase (CAT) enzymes, which are found in a large number of species. " 583 UPDATE SHV-100 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 580 UPDATE TEM-110 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 581 UPDATE QnrB19 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1632 UPDATE CTX-M-53 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 588 UPDATE OKP-A-7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 589 UPDATE TEM-145 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1633 UPDATE catQ determinant of phenicol resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of phenicol resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to phenicol (chloramphenicol) antibiotics. These include chloramphenicol acetyltransferase (CAT) enzymes, which are found in a large number of species. " 1634 UPDATE CMY-78 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1635 UPDATE vanRG determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1436 UPDATE TEM-40 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1434 UPDATE Erm(35) antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 1432 UPDATE Mycobacterium tuberculosis mutant embC conferring resistance to ethambutol antibiotic resistant gene variant or mutant; determinant of resistance to polyamine antibiotics; ARO_category "UPDATED category_aro_name with determinant of resistance to polyamine antibiotics " 1433 UPDATE CMY-18 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1430 UPDATE SHV-125 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1431 UPDATE GES-15 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 418 UPDATE OXA-325 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1637 UPDATE MOX-7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1438 UPDATE SHV-19 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1439 UPDATE SHV-80 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1260 UPDATE APH(3')-IVa antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 458 UPDATE tet(B) efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with tet(B) " 1349 UPDATE IND-2a antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 450 UPDATE OXA-51 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 451 UPDATE LRA-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1342 UPDATE plasmid-encoded cat (pp-cat) determinant of phenicol resistance; antibiotic inactivation enzyme; ARO_category; model_name "UPDATED category_aro_name with determinant of phenicol resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to phenicol (chloramphenicol) antibiotics. These include chloramphenicol acetyltransferase (CAT) enzymes, which are found in a large number of species. UPDATED model_name with plasmid-encoded cat (pp-cat) " 1343 UPDATE OXA-166 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 454 UPDATE KPC-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 455 UPDATE vanC determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1346 UPDATE SHV-94 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1347 UPDATE OXA-425 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1082 UPDATE CTX-M-7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 517 UPDATE QnrD2 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1502 UPDATE OXA-209 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1503 UPDATE LEN-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1500 UPDATE APH(6)-Ia antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1501 UPDATE CMY-49 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1506 UPDATE ACT-12 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 653 UPDATE AAC(3)-VIIa antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1504 UPDATE CMY-108 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1505 UPDATE SAT-4 determinant of resistance to nucleoside antibiotics; antibiotic inactivation enzyme; ARO_category; model_name "UPDATED category_aro_name with determinant of resistance to nucleoside antibiotics UPDATED model_name with SAT-4 " 1508 UPDATE QnrA2 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1509 UPDATE vanXF determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 658 UPDATE CMY-104 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 659 UPDATE AAC(6')-29b antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1992 UPDATE dfrA1 antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 2127 UPDATE Borrelia burgdorferi 16S rRNA mutation conferring resistance to kanamycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2126 UPDATE Mycobacterium abscessus 16S rRNA mutation conferring resistance to tobramycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2129 UPDATE Escherichia coli 16S rRNA (rrsB) mutation conferring resistance to spectinomycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2128 UPDATE Mycobacterium abscessus 16S rRNA mutation conferring resistance to gentamicin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1292 UPDATE CTX-M-109 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1376 UPDATE MOX-6 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 322 UPDATE FEZ-1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 323 UPDATE aadA9 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 320 UPDATE Streptococcus pneumoniae PBP2x conferring resistance to amoxicillin antibiotic resistant gene variant or mutant; determinant of beta-lactam resistance; ARO_category; model_name "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. UPDATED model_name with Streptococcus pneumoniae PBP2x conferring resistance to amoxicillin " 321 UPDATE CTX-M-35 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 326 UPDATE OXA-225 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 327 UPDATE GES-17 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 324 UPDATE QnrB54 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 325 UPDATE LEN-23 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 329 UPDATE CTX-M-159 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2330 UPDATE leuO determinant of sulfonamide resistance; protein(s) and two-component regulatory system modulating antibiotic efflux; ARO_category "UPDATED category_aro_name with determinant of sulfonamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to sulfonamide antibiotics. " 2331 UPDATE kdpE determinant of aminoglycoside resistance; protein(s) and two-component regulatory system modulating antibiotic efflux; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2332 UPDATE mfd antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 2333 UPDATE LEN-26 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2335 UPDATE ADC-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1594 UPDATE VgbA antibiotic inactivation enzyme; determinant of streptogramin resistance; ARO_category "UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 1341 UPDATE OXA-53 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1995 UPDATE AAC(6')-Iz antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2482 UPDATE Chlamydomonas reinhardtii 16S rRNA (rrnS) mutation conferring resistance to streptomycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1598 UPDATE OXA-101 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2248 UPDATE fusD antibiotic inactivation enzyme; determinant of fusidic acid resistance; ARO_category "UPDATED category_aro_name with determinant of fusidic acid resistance " 2249 UPDATE LpxA gene conferring antibiotic resistance via molecular bypass; determinant of polymyxin resistance; antibiotic resistant gene variant or mutant; ARO_category; model_param "UPDATED category_aro_name with determinant of polymyxin resistance UPDATED param_description with A parameter to describe the mapped insertion or deletion. For an insertion: insert the location and genetic sequence of the insertion. For a deletion: insert the location of the deletion. For nucleotide space: insertion: [nt][position]+[number of nucleotides]:[nucleotides] eg. nt312+1:G. For protein space: insertion: +[amino acids][start position:end position] eg. +S3:12. If both are known, a ""/"" may be used to separate the protein and nucleotide notation eg. nt312+3:AGC/+S312. " 2244 UPDATE vanSI determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 2245 UPDATE vanKI determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category; model_name "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. UPDATED model_name with vanKI " 2246 UPDATE vanRI determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category; model_name "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. UPDATED model_name with vanRI " 2240 UPDATE vanJ determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 2241 UPDATE vanI determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category; model_name "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. UPDATED model_name with vanI " 2242 UPDATE vanWI determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 2243 UPDATE vanXI determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category; model_name "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. UPDATED model_name with vanXI " 995 UPDATE mexG efflux pump complex or subunit conferring antibiotic resistance; ARO_name "UPDATED ARO_name with MexG " 994 UPDATE SHV-77 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 997 UPDATE VIM-31 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 996 UPDATE CMY-77 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 991 UPDATE EreA determinant of macrolide resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. " 990 UPDATE FOX-9 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2462 UPDATE Propionibacterium acnes gyrA conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 992 UPDATE SHV-66 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 999 UPDATE LEN-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 998 UPDATE SHV-134 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 120 UPDATE aadA4 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 122 UPDATE VIM-34 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 123 UPDATE SHV-64 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 124 UPDATE IND-7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 125 UPDATE SHV-182 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 126 UPDATE TEM-183 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 127 UPDATE clbB determinant of phenicol resistance; determinant of macrolide resistance; determinant of linezolid resistance; antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; ARO_category "UPDATED category_aro_name with determinant of linezolid resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to linezolid antibiotics. UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of phenicol resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to phenicol (chloramphenicol) antibiotics. These include chloramphenicol acetyltransferase (CAT) enzymes, which are found in a large number of species. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 129 UPDATE FosX antibiotic inactivation enzyme; determinant of fosfomycin resistance; ARO_category "UPDATED category_aro_name with determinant of fosfomycin resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fosfomycin antibiotics. " 2068 UPDATE Escherichia coli 16S rRNA mutation conferring resistance to edeine determinant of resistance to peptide antibiotics; antibiotic resistant gene variant or mutant; determinant of resistance to polyamine antibiotics; ARO_category "UPDATED category_aro_name with determinant of resistance to peptide antibiotics UPDATED category_aro_name with determinant of resistance to polyamine antibiotics " 2069 UPDATE Escherichia coli 16S rRNA (rrsB) mutation conferring resistance to neomycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2060 UPDATE FosC2 antibiotic inactivation enzyme; determinant of fosfomycin resistance; ARO_category "UPDATED category_aro_name with determinant of fosfomycin resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fosfomycin antibiotics. " 2061 UPDATE VIM-7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2062 UPDATE mphC determinant of macrolide resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. " 2063 UPDATE blaR1 antibiotic resistance gene cluster, cassette, or operon; determinant of beta-lactam resistance; gene modulating beta-lactam resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2064 UPDATE TEM-196 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2065 UPDATE CMY-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2066 UPDATE Escherichia coli soxS mutant efflux pump complex or subunit conferring antibiotic resistance; antibiotic resistant gene variant or mutant; protein modulating permeability to antibiotic; protein(s) and two-component regulatory system modulating antibiotic efflux; model_name; ARO_name "UPDATED model_name with Escherichia coli soxS with mutation conferring antibiotic resistance UPDATED ARO_name with Escherichia coli soxS with mutation conferring antibiotic resistance " 2666 UPDATE antibiotic resistant fabI antibiotic resistant gene variant or mutant; determinant of isoniazid resistance; determinant of triclosan resistance; ARO_category; model_param "UPDATED category_aro_name with determinant of isoniazid resistance UPDATED category_aro_name with determinant of triclosan resistance UPDATED param_value with 1e-60 UPDATED param_type_id with 36302 UPDATED param_type with BLASTP e-value UPDATED param_description with A curated expectation value (e-value) for assignment of an Antibiotic Resistance Ontology term based on a BLASTP hit to a CARD reference sequence. " 2660 UPDATE Enterobacter cloacae acrA efflux pump complex or subunit conferring antibiotic resistance; model_param "UPDATED param_value with 760 UPDATED param_value with 1e-200 UPDATED param_type_id with 36302 UPDATED param_type with BLASTP e-value UPDATED param_description with A curated expectation value (e-value) for assignment of an Antibiotic Resistance Ontology term based on a BLASTP hit to a CARD reference sequence. " 723 UPDATE SHV-72 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1397 UPDATE dfrC antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 1645 UPDATE ACT-23 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1644 UPDATE SHV-70 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1647 UPDATE mexI efflux pump complex or subunit conferring antibiotic resistance; ARO_name "UPDATED ARO_name with MexI " 1646 UPDATE TEM-139 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1641 UPDATE OXA-203 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1640 UPDATE MIR-14 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1643 UPDATE arnA determinant of polymyxin resistance; gene altering cell wall charge; ARO_category "UPDATED category_aro_name with determinant of polymyxin resistance " 1642 UPDATE clbC determinant of phenicol resistance; determinant of macrolide resistance; determinant of linezolid resistance; antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; ARO_category "UPDATED category_aro_name with determinant of linezolid resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to linezolid antibiotics. UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of phenicol resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to phenicol (chloramphenicol) antibiotics. These include chloramphenicol acetyltransferase (CAT) enzymes, which are found in a large number of species. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 1396 UPDATE OXA-11 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1649 UPDATE DHA-21 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1648 UPDATE CTX-M-2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 728 UPDATE TEM-192 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 729 UPDATE CTX-M-8 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 578 UPDATE SHV-11 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 573 UPDATE OXA-136 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 572 UPDATE OXA-137 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 571 UPDATE clbA determinant of phenicol resistance; determinant of macrolide resistance; determinant of linezolid resistance; antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; ARO_category "UPDATED category_aro_name with determinant of linezolid resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to linezolid antibiotics. UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of phenicol resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to phenicol (chloramphenicol) antibiotics. These include chloramphenicol acetyltransferase (CAT) enzymes, which are found in a large number of species. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 570 UPDATE Streptococcus pyogenes folP with mutation conferring resistance to sulfonamides antibiotic resistant gene variant or mutant; determinant of sulfonamide resistance; ARO_category; model_name "UPDATED category_aro_name with determinant of sulfonamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to sulfonamide antibiotics. UPDATED model_name with Streptococcus pyogenes folP with mutation conferring resistance to sulfonamides " 577 UPDATE QnrB65 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 576 UPDATE MIR-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 575 UPDATE AAC(3)-Ib antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 574 UPDATE AAC(6')-Ia antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1209 UPDATE QnrB45 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1208 UPDATE SHV-173 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1421 UPDATE TEM-85 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2406 UPDATE rpsJ antibiotic target protection protein; determinant of tetracycline resistance; ARO_category "UPDATED category_aro_name with determinant of tetracycline resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to tetracycline antibiotics or tetracycline-like derivatives. " 1423 UPDATE TEM-15 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1422 UPDATE ACC-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1425 UPDATE RbpA antibiotic target protection protein; determinant of rifamycin resistance; ARO_category "UPDATED category_aro_name with determinant of rifamycin resistance UPDATED category_aro_description with Enzymes, other proteins, or other gene products shown clinically to confer resistance to rifamycin (rifampin) antibiotics. " 1394 UPDATE OXA-257 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2407 UPDATE Capnocytophaga gingivalis gyrA conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1429 UPDATE SHV-60 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1428 UPDATE cphA2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 939 UPDATE CTX-M-113 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 731 UPDATE IMP-11 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 730 UPDATE AAC(6')-IIc antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 938 UPDATE QnrB70 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 735 UPDATE TEM-30 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 734 UPDATE vanTC determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 737 UPDATE MIR-8 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 736 UPDATE arr-7 determinant of rifamycin resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of rifamycin resistance UPDATED category_aro_description with Enzymes, other proteins, or other gene products shown clinically to confer resistance to rifamycin (rifampin) antibiotics. " 739 UPDATE LRA-18 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 738 UPDATE AAC(6')-Iae antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1359 UPDATE OXA-233 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1358 UPDATE VIM-24 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 469 UPDATE SHV-49 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 468 UPDATE Erm(37) antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 465 UPDATE vanSO determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 464 UPDATE NDM-13 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 467 UPDATE CARB-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 466 UPDATE CTX-M-76 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1357 UPDATE CTX-M-132 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 460 UPDATE CMY-29 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1355 UPDATE TEM-149 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 462 UPDATE Staphylococcus aureus pgsA mutations conferring resistance to daptomycin antibiotic resistant gene variant or mutant; determinant of resistance to lipopeptide antibiotics; ARO_category; model_param "UPDATED category_aro_name with determinant of resistance to lipopeptide antibiotics UPDATED param_description with A parameter to describe the mapped insertion or deletion. For an insertion: insert the location and genetic sequence of the insertion. For a deletion: insert the location of the deletion. For nucleotide space: insertion: [nt][position]+[number of nucleotides]:[nucleotides] eg. nt312+1:G. For protein space: insertion: +[amino acids][start position:end position] eg. +S3:12. If both are known, a ""/"" may be used to separate the protein and nucleotide notation eg. nt312+3:AGC/+S312. " 1273 UPDATE otr(A) antibiotic target protection protein; determinant of tetracycline resistance; ARO_category; model_name "UPDATED category_aro_name with determinant of tetracycline resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to tetracycline antibiotics or tetracycline-like derivatives. UPDATED model_name with otr(A) " 2158 UPDATE Escherichia coli EF-Tu mutants conferring resistance to Pulvomycin antibiotic resistant gene variant or mutant; determinant of elfamycin resistance; ARO_category "UPDATED category_aro_name with determinant of elfamycin resistance " 1519 UPDATE vatE antibiotic inactivation enzyme; determinant of streptogramin resistance; ARO_category "UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 1518 UPDATE EreA2 determinant of macrolide resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. " 1515 UPDATE NDM-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1514 UPDATE IMP-28 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1517 UPDATE OXA-33 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 934 UPDATE IMP-8 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1274 UPDATE VIM-10 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1510 UPDATE vanTrL determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1513 UPDATE QnrB64 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1512 UPDATE SME-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 281 UPDATE CMY-110 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1735 UPDATE vatA antibiotic inactivation enzyme; determinant of streptogramin resistance; ARO_category "UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 1275 UPDATE ErmT antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 1004 UPDATE vanRD determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 280 UPDATE CTX-M-11 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 582 UPDATE FOX-7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 357 UPDATE VIM-38 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 356 UPDATE ErmU antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 355 UPDATE TEM-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 354 UPDATE QnrB24 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 353 UPDATE QnrB2 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 352 UPDATE PDC-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 351 UPDATE SHV-6 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 359 UPDATE TEM-112 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 358 UPDATE QnrB42 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 43 UPDATE tet(42) efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with tet(42) " 1033 UPDATE vanSN determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1447 UPDATE OKP-A-10 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2321 UPDATE cdeA efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with cdeA " 2326 UPDATE TLA-3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2325 UPDATE Mrx antibiotic inactivation enzyme; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. " 1446 UPDATE PDC-6 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2329 UPDATE MOX-9 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2328 UPDATE MUS-2 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 289 UPDATE OXA-85 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 288 UPDATE CMY-60 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1444 UPDATE IND-12 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1793 UPDATE DHA-14 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 5 UPDATE dfrF antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 283 UPDATE CMY-85 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 282 UPDATE CTX-M-125 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 285 UPDATE TEM-11 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 287 UPDATE TEM-67 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 286 UPDATE SHV-162 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1441 UPDATE Enterobacter aerogenes omp36 with mutation antibiotic resistant gene variant or mutant; determinant of beta-lactam resistance; protein modulating permeability to antibiotic; ARO_category; model_name "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. UPDATED model_name with Enterobacter aerogenes omp36 with mutation " 1116 UPDATE arr-2 determinant of rifamycin resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of rifamycin resistance UPDATED category_aro_description with Enzymes, other proteins, or other gene products shown clinically to confer resistance to rifamycin (rifampin) antibiotics. " 263 UPDATE dfrA24 antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 262 UPDATE VIM-8 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 261 UPDATE CMY-65 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 260 UPDATE ErmN antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 267 UPDATE OXA-43 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 266 UPDATE QnrB13 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 265 UPDATE SHV-128 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 264 UPDATE lsaE efflux pump complex or subunit conferring antibiotic resistance; model_param "UPDATED param_value with 850 UPDATED param_type_id with 40725 UPDATED param_type with BLASTP bit-score UPDATED param_description with A score is a numerical value that describes the overall quality of an alignment. Higher numbers correspond to higher similarity. The bit-score (S) is determined by the following formula: S = (λ × S − lnK)/ ln2 where λ is the Gumble distribution constant, S is the raw alignment score, and K is a constant associated with the scoring matrix. " 269 UPDATE CMY-8 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 268 UPDATE CfxA6 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1290 UPDATE TEM-141 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1291 UPDATE TEM-177 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1296 UPDATE OKP-B-12 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1297 UPDATE CTX-M-80 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1294 UPDATE Sed1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2259 UPDATE mphG antibiotic inactivation enzyme; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. " 2257 UPDATE Planobispora rosea EF-Tu mutants conferring resistance to inhibitor GE2270A antibiotic resistant gene variant or mutant; determinant of elfamycin resistance; ARO_category; model_param "UPDATED category_aro_name with determinant of elfamycin resistance UPDATED param_value with 1e-100 UPDATED param_type_id with 36302 UPDATED param_type with BLASTP e-value UPDATED param_description with A curated expectation value (e-value) for assignment of an Antibiotic Resistance Ontology term based on a BLASTP hit to a CARD reference sequence. " 1295 UPDATE catII determinant of phenicol resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of phenicol resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to phenicol (chloramphenicol) antibiotics. These include chloramphenicol acetyltransferase (CAT) enzymes, which are found in a large number of species. " 2251 UPDATE LpxC gene conferring antibiotic resistance via molecular bypass; determinant of polymyxin resistance; antibiotic resistant gene variant or mutant; ARO_category; model_param "UPDATED category_aro_name with determinant of polymyxin resistance UPDATED param_description with A parameter to describe the mapped insertion or deletion. For an insertion: insert the location and genetic sequence of the insertion. For a deletion: insert the location of the deletion. For nucleotide space: insertion: [nt][position]+[number of nucleotides]:[nucleotides] eg. nt312+1:G. For protein space: insertion: +[amino acids][start position:end position] eg. +S3:12. If both are known, a ""/"" may be used to separate the protein and nucleotide notation eg. nt312+3:AGC/+S312. " 988 UPDATE tet(J) efflux pump complex or subunit conferring antibiotic resistance; model_name "UPDATED model_name with tet(J) " 989 UPDATE ErmG antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 982 UPDATE TEM-153 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 983 UPDATE GES-20 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 980 UPDATE y56 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 981 UPDATE OXA-86 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 987 UPDATE CTX-M-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 984 UPDATE Bartonella bacilliformis gyrA conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 2478 UPDATE Helicobacter pylori 16S rRNA mutation conferring resistance to tetracycline antibiotic resistant gene variant or mutant; determinant of tetracycline resistance; ARO_category "UPDATED category_aro_name with determinant of tetracycline resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to tetracycline antibiotics or tetracycline-like derivatives. " 115 UPDATE TEM-87 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2198 UPDATE Pseudomonas aeruginosa parE conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1790 UPDATE vanHF determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 116 UPDATE QnrB18 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 111 UPDATE Escherichia coli gyrB conferring resistance to aminocoumarin determinant of aminocoumarin resistance; antibiotic resistant gene variant or mutant; ARO_category "UPDATED category_aro_name with determinant of aminocoumarin resistance " 110 UPDATE AAC(6')-Iu antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 113 UPDATE VEB-5 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 112 UPDATE FosA5 antibiotic inactivation enzyme; determinant of fosfomycin resistance; ARO_category "UPDATED category_aro_name with determinant of fosfomycin resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fosfomycin antibiotics. " 119 UPDATE VIM-12 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 118 UPDATE LRA-9 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1797 UPDATE ErmY antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 2079 UPDATE sgm antibiotic target modifying enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2078 UPDATE Mycobacterium chelonae 16S rRNA mutation conferring resistance to kanamycin A antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2073 UPDATE Escherichia coli 16S rRNA (rrsB) mutation conferring resistance to G418 antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2072 UPDATE NmcR antibiotic inactivation enzyme; determinant of beta-lactam resistance; gene modulating beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2071 UPDATE AAC(6')-Ib8 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2070 UPDATE Mycobacterium tuberculosis 16S rRNA mutation conferring resistance to amikacin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2077 UPDATE Mycobacterium smegmatis 16S rRNA (rrsA) mutation conferring resistance to neomycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2076 UPDATE Neisseria gonorrhoeae 16S rRNA mutation conferring resistance to spectinomycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 2075 UPDATE Salmonella enterica soxR mutants efflux pump complex or subunit conferring antibiotic resistance; antibiotic resistant gene variant or mutant; protein(s) and two-component regulatory system modulating antibiotic efflux; model_name; ARO_name "UPDATED model_name with Salmonella enterica soxR with mutation conferring antibiotic resistance UPDATED ARO_name with Salmonella enterica soxR with mutation conferring antibiotic resistance " 2074 UPDATE Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin antibiotic resistant gene variant or mutant; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1796 UPDATE CMY-119 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1035 UPDATE Streptococcus pneumoniae PBP2b conferring resistance to amoxicillin antibiotic resistant gene variant or mutant; determinant of beta-lactam resistance; ARO_category; model_name "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. UPDATED model_name with Streptococcus pneumoniae PBP2b conferring resistance to amoxicillin " 1389 UPDATE KPC-22 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1986 UPDATE OXA-309 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1987 UPDATE QnrA1 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1984 UPDATE SHV-144 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1985 UPDATE SHV-7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1982 UPDATE IMP-9 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1983 UPDATE vanTN determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1980 UPDATE OXA-247 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1981 UPDATE vanA determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1638 UPDATE CMY-111 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1639 UPDATE SHV-84 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1988 UPDATE CMY-7 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1989 UPDATE Klebsiella pneumoniae acrR mutant resulting in high level antibiotic resistance efflux pump complex or subunit conferring antibiotic resistance; antibiotic resistant gene variant or mutant; protein(s) and two-component regulatory system modulating antibiotic efflux; model_name; ARO_name "UPDATED model_name with Klebsiella pneumoniae acrR with mutation conferring multidrug antibiotic resistance UPDATED ARO_name with Klebsiella pneumoniae acrR with mutation conferring multidrug antibiotic resistance " 568 UPDATE CTX-M-20 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 569 UPDATE OXA-228 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 560 UPDATE OXA-77 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 561 UPDATE OKP-B-8 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 562 UPDATE TEM-187 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 563 UPDATE OKP-B-6 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 564 UPDATE IMP-22 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 565 UPDATE SHV-82 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 566 UPDATE OXA-32 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 567 UPDATE CTX-M-41 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1188 UPDATE ErmV antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 1189 UPDATE vatB antibiotic inactivation enzyme; determinant of streptogramin resistance; ARO_category "UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 1186 UPDATE OXA-327 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1187 UPDATE OXA-248 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1184 UPDATE OXA-182 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1185 UPDATE OXA-176 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1182 UPDATE CTX-M-105 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1183 UPDATE tetQ antibiotic target protection protein; determinant of tetracycline resistance; ARO_category "UPDATED category_aro_name with determinant of tetracycline resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to tetracycline antibiotics or tetracycline-like derivatives. " 726 UPDATE PC1 beta-lactamase (blaZ) antibiotic resistance gene cluster, cassette, or operon; antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 727 UPDATE ErmS antibiotic target modifying enzyme; determinant of lincosamide resistance; determinant of streptogramin resistance; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of lincosamide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to lincosamide antibiotics. UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. UPDATED category_aro_name with determinant of streptogramin resistance UPDATED category_aro_description with Ezymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics. " 724 UPDATE AAC(6')-Ij antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 725 UPDATE GES-11 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 722 UPDATE vanRA determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1749 UPDATE IMP-18 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 720 UPDATE BcI antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 721 UPDATE OXA-28 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1745 UPDATE KPC-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1746 UPDATE IMP-24 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1747 UPDATE CMY-103 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1740 UPDATE TEM-53 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1741 UPDATE OXA-359 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1742 UPDATE SHV-28 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1743 UPDATE OXA-338 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1164 UPDATE MIR-9 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1165 UPDATE OKP-A-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1166 UPDATE Staphylococcus aureus gyrA conferring resistance to fluoroquinolones antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1160 UPDATE QnrB34 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1162 UPDATE aadA15 antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1163 UPDATE CMY-94 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1168 UPDATE NDM-9 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1169 UPDATE OXA-360 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 48 UPDATE OXA-90 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 49 UPDATE tsnr antibiotic target modifying enzyme; determinant of resistance to peptide antibiotics; ARO_category "UPDATED category_aro_name with determinant of resistance to peptide antibiotics " 46 UPDATE CMY-114 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 47 UPDATE OXA-60 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 42 UPDATE OXY-6-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 2034 UPDATE TEM-108 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 40 UPDATE QnrB58 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 41 UPDATE rmtH antibiotic target modifying enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1568 UPDATE OXA-183 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1569 UPDATE catD determinant of phenicol resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of phenicol resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to phenicol (chloramphenicol) antibiotics. These include chloramphenicol acetyltransferase (CAT) enzymes, which are found in a large number of species. " 1299 UPDATE AAC(6')-Ic antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1560 UPDATE OKP-B-20 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1561 UPDATE vanTG determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1562 UPDATE aad(6) antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 1563 UPDATE CTX-M-63 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1564 UPDATE QnrB16 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1565 UPDATE ACT-18 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1566 UPDATE vanXD determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 1567 UPDATE FosB antibiotic inactivation enzyme; determinant of fosfomycin resistance; ARO_category "UPDATED category_aro_name with determinant of fosfomycin resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fosfomycin antibiotics. " 1713 UPDATE vanYM determinant of resistance to glycopeptide antibiotics; gene conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_category "UPDATED category_aro_name with determinant of resistance to glycopeptide antibiotics UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to glycopeptide antibiotics. " 474 UPDATE dfrD antibiotic target replacement protein; determinant of diaminopyrimidine resistance; ARO_category "UPDATED category_aro_name with determinant of diaminopyrimidine resistance " 796 UPDATE iri determinant of rifamycin resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of rifamycin resistance UPDATED category_aro_description with Enzymes, other proteins, or other gene products shown clinically to confer resistance to rifamycin (rifampin) antibiotics. " 1361 UPDATE OXA-223 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1711 UPDATE AQU-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1381 UPDATE CcrA beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1710 UPDATE Mycobacterium leprae gyrB conferring resistance to fluoroquinolone antibiotic resistant gene variant or mutant; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 1717 UPDATE OXA-230 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1716 UPDATE OXA-398 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1715 UPDATE OXA-73 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 732 UPDATE OXA-237 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 790 UPDATE CMY-32 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 472 UPDATE TEM-128 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 473 UPDATE mphE antibiotic inactivation enzyme; determinant of macrolide resistance; ARO_category "UPDATED category_aro_name with determinant of macrolide resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to macrolide antibiotics. " 470 UPDATE OXA-4 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 471 UPDATE TEM-151 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1362 UPDATE IMP-31 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 477 UPDATE catP determinant of phenicol resistance; antibiotic inactivation enzyme; ARO_category "UPDATED category_aro_name with determinant of phenicol resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to phenicol (chloramphenicol) antibiotics. These include chloramphenicol acetyltransferase (CAT) enzymes, which are found in a large number of species. " 1360 UPDATE Bartonella bacilliformis gyrB conferring resistance to aminocoumarin determinant of aminocoumarin resistance; antibiotic resistant gene variant or mutant; ARO_category "UPDATED category_aro_name with determinant of aminocoumarin resistance " 475 UPDATE OXA-106 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 478 UPDATE AAC(3)-IIa antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_category "UPDATED category_aro_name with determinant of aminoglycoside resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to aminoglycoside antibiotics. " 479 UPDATE IMP-29 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_category "UPDATED category_aro_name with determinant of beta-lactam resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to beta-lactam antibiotics. " 1369 UPDATE QnrB69 antibiotic target protection protein; determinant of fluoroquinolone resistance; ARO_category "UPDATED category_aro_name with determinant of fluoroquinolone resistance UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to fluoroquinolone antibiotics " 2327 DELETE aminocoumarin resistant cysB aminocoumarin resistance protein; antibiotic resistant gene variant or mutant; N/A N/A 2319 DELETE aminocoumarin resistant alaS aminocoumarin resistance protein; antibiotic resistant gene variant or mutant; N/A N/A 2420 DELETE drrC efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 733 DELETE cpxR efflux pump complex or subunit conferring antibiotic resistance; protein(s) and two-component regulatory system modulating antibiotic efflux; N/A N/A 2419 DELETE drrB efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2418 DELETE drrA efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2734 ADD PmpM efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2712 ADD MexXY-OprA efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2711 ADD MexXY-OprM efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2716 ADD OpmB efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2731 ADD MexJK-OpmH efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2732 ADD MexVW-OprM efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2733 ADD TriABC-OpmH efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2718 ADD MuxB efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2717 ADD MuxA efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2743 ADD Escherichia coli AcrAB-TolC with AcrR mutation conferring resistance to ciprofloxacin, tetracycline, and ceftazidime efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2688 ADD ArmR efflux pump complex or subunit conferring antibiotic resistance; protein(s) and two-component regulatory system modulating antibiotic efflux; N/A N/A 2744 ADD Escherichia coli AcrAB-TolC with MarR mutations conferring resistance to ciprofloxacin and tetracycline efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2685 ADD Pseudomonas aeruginosa CpxR efflux pump complex or subunit conferring antibiotic resistance; protein(s) and two-component regulatory system modulating antibiotic efflux; N/A N/A 2686 ADD MexAB-OprM with CpxR regulator conferring resistance to ciprofloxacin, ceftazidime, and aztreonam efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2680 ADD MexAB-OprM with prematurely terminated MexR conferring resistance to meropenem and ciprofloxacin efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2681 ADD antibiotic resistant fabG antibiotic resistant gene variant or mutant; determinant of triclosan resistance; N/A N/A 2682 ADD MexAB-OprM with NalC mutations conferring resistance to aztreonam efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2689 ADD Staphylococcus aureus 23S rRNA with mutation conferring resistance to linezolid antibiotic resistant gene variant or mutant; N/A N/A 2724 ADD MuxABC-OpmB efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2720 ADD MuxC efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2705 ADD MexEF-OprN with MexS mutations conferring resistance to chloramphenicol and ciprofloxacin efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2704 ADD MexEF-OprN with MexT mutation conferring resistance to chloramphenicol and ciprofloxacin efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2707 ADD MexEF-OprN with MvaT deletion conferring resistance to chloramphenicol and norfloxacin efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2745 ADD AcrAB-TolC efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2729 ADD MexJK-OprM efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2679 ADD MexAB-OprM with MexR mutations confers resistance to multiple antibiotics efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2694 ADD MexCD-OprJ with type A NfxB mutation efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2706 ADD MvaT efflux pump complex or subunit conferring antibiotic resistance; protein(s) and two-component regulatory system modulating antibiotic efflux; N/A N/A 2713 ADD MexXY-OprM efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2698 ADD MexCD-OprJ with NfxB mutation conferring resistance to ciprofloxacin efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2697 ADD EdeQ determinant of resistance to peptide antibiotics; antibiotic inactivation enzyme; gene involved in self-resistance to antibiotic; determinant of resistance to polyamine antibiotics; N/A N/A 2695 ADD MexCD-OprJ with type B NfxB mutation efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2683 ADD MexAB-OprM with NalD mutations conferring resistance to multiple antibiotics efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2693 ADD Type B NfxB efflux pump complex or subunit conferring antibiotic resistance; protein(s) and two-component regulatory system modulating antibiotic efflux; N/A N/A 2691 ADD Type A NfxB efflux pump complex or subunit conferring antibiotic resistance; protein(s) and two-component regulatory system modulating antibiotic efflux; N/A N/A