Model_id Action ARO_name ARO_category Changes To Summary 882 UPDATE NPS beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; model_name; ARO_name "UPDATED model_name with class A Rhodobacter capsulatus beta-lactamase UPDATED ARO_name with class A Rhodopseudomonas capsulata beta-lactamase " 2234 UPDATE MSI-OXA antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_description "UPDATED ARO_description with MSI-OXA is an OXA-85-like class D beta lactamase isolated from Massilia oculi. " 627 UPDATE Escherichia coli rpoB mutants conferring resistance to rifampicin determinant of rifamycin resistance; antibiotic resistant gene variant or mutant; antibiotic target replacement protein; ARO_category "UPDATED category_aro_name with antibiotic target replacement protein UPDATED category_aro_cvterm_id with 36520 UPDATED category_aro_accession with 3000381 UPDATED category_aro_description with Alternate proteins that have the same functions as other antibiotic target proteins, but are structurally different and thus resistant to antibiotics. These can replace the activity of other antibiotic-sensitive proteins in the presence of antibiotics. " 603 UPDATE mdtG efflux pump complex or subunit conferring antibiotic resistance; model_param "UPDATED param_value with 700 " 624 UPDATE Mycobacterium leprae rpoB mutations conferring resistance to rifampicin determinant of rifamycin resistance; antibiotic resistant gene variant or mutant; antibiotic target replacement protein; ARO_category "UPDATED category_aro_name with antibiotic target replacement protein UPDATED category_aro_cvterm_id with 36520 UPDATED category_aro_accession with 3000381 UPDATED category_aro_description with Alternate proteins that have the same functions as other antibiotic target proteins, but are structurally different and thus resistant to antibiotics. These can replace the activity of other antibiotic-sensitive proteins in the presence of antibiotics. " 51 UPDATE AAC(3)-IIIc antibiotic inactivation enzyme; determinant of aminoglycoside resistance; model_param "UPDATED param_value with 500 " 1206 UPDATE qepA efflux pump complex or subunit conferring antibiotic resistance; ARO_description; ARO_name "UPDATED ARO_description with QepA is a plasmid-mediated efflux pump in E. coli, shown to contribute to fluoroquinolone resistance. It is regulated by sox genes, also known as global stress regulators. UPDATED ARO_name with QepA " 1200 UPDATE msrA efflux pump complex or subunit conferring antibiotic resistance; model_sequences; model_param "UPDATED fmax with 16258 UPDATED strand with + UPDATED accession with NC_022598.1 UPDATED fmin with 14791 UPDATED sequence with ATGGAACAATATACAATTAAATTTAACCAAATCAATCATAAATTGACAGATTTACGATCACTTAACATCGATCATCTTTATGCTTACCAATTTGAAAAAATAGCACTTATTGGGGGTAATGGTACTGGCAAAACCACATTACTAAATATGATTGCTCAAAAAACAAAACCAGAATCTGGAACAGTTGAAACGAATGGCGAAATTCAATATTTTGAACAGCTTAACATGGATGTGGAAAATGATTTTAACACGTTAGACGGTAGTTTAATGAGTGAACTCCATATACCTATGCATACAACCGACAGTATGAGTGGTGGTGAAAAAGCAAAATATAAATTAGCTAATGTCATATCAAATTATAGTCCGATATTACTTTTAGATGAACCTACAAATCACTTGGATAAAATTGGTAAAGATTATCTGAATAATATTTTAAAATATTACTATGGTACTTTAATTATAGTAAGTCACGATAGAGCACTTATAGACCAAATTGCTGACACAATTTGGGATATACAAGAAGATGGCACAATAAGAGTGTTTAAAGGTAATTACACACAGTATCAAAATCAATATGAACAAGAACAGTTAGAACAACAACGTAAATATGAACAGTATATAAGTGAAAAACAAAGATTGTCCCAAGCCAGTAAAGCTAAACGAAATCAAGCGCAACAAATGGCACAAGCATCATCAAAACAAAAAAATAAAAGTATAGCACCAGATCGTTTAAGTGCATCAAAACAAAAAGGCACGGTTGAGAAGGCTGCTCAAAAACAAGCTAAGCATATTGAAAAAAGAATGGAACATTTGGAAGAAGTTGAAAAACCACAAAGTTATCATGAATTCAATTTTCCACAAAATAAAATTTATGATATCCATAATAATTATCCAATCATTGCACAAAATCTAACATTGGTTAAAGGAAGTCAAAAACTGCTAACACAAGTACGATTCCAAATACCATATGGCAAAAATATAGCGCTCGTAGGTGCAAATGGTGTAGGTAAGACAACTTTACTTGAAGCTATTTACCACCAAATAGAGGGAATTGATTGTTCTCCTAAAGTGCAAATGGCATACTATCGTCAACTTGCTTATGAAGACATGCGTGACGTTTCATTATTGCAATATTTAATGGATGAAACGGATTCATCAGAATCATTCAGTAGAGCTATTTTAAATAACTTGGGTTTAAATGAAGCACTTGAGCGTTCTTGTAATGTTTTGAGTGGTGGGGAAAGAACGAAATTATCGTTAGCAGTATTATTTTCAACGAAAGCGAATATGTTAATTTTGGATGAACCAACTAATTTTTTAGATATTAAAACATTAGAAGCATTAGAAATGTTTATGAATAAATATCCTGGAATCATTTTGTTTACATCACATGATACAAGGTTTGTTAAACATGTATCAGATAAAAAATGGGAATTAACAGGACAATCTATTCATGATATAACTTAA UPDATED NCBI_taxonomy_name with Staphylococcus aureus UPDATED NCBI_taxonomy_id with 1280 UPDATED NCBI_taxonomy_cvterm_id with 35508 UPDATED accession with YP_008709794.1 UPDATED sequence with MEQYTIKFNQINHKLTDLRSLNIDHLYAYQFEKIALIGGNGTGKTTLLNMIAQKTKPESGTVETNGEIQYFEQLNMDVENDFNTLDGSLMSELHIPMHTTDSMSGGEKAKYKLANVISNYSPILLLDEPTNHLDKIGKDYLNNILKYYYGTLIIVSHDRALIDQIADTIWDIQEDGTIRVFKGNYTQYQNQYEQEQLEQQRKYEQYISEKQRLSQASKAKRNQAQQMAQASSKQKNKSIAPDRLSASKQKGTVEKAAQKQAKHIEKRMEHLEEVEKPQSYHEFNFPQNKIYDIHNNYPIIAQNLTLVKGSQKLLTQVRFQIPYGKNIALVGANGVGKTTLLEAIYHQIEGIDCSPKVQMAYYRQLAYEDMRDVSLLQYLMDETDSSESFSRAILNNLGLNEALERSCNVLSGGERTKLSLAVLFSTKANMLILDEPTNFLDIKTLEALEMFMNKYPGIILFTSHDTRFVKHVSDKKWELTGQSIHDIT UPDATED param_value with 400 " 332 UPDATE r39 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_name "UPDATED ARO_name with R39 " 392 UPDATE TUS-1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_name "UPDATED ARO_name with TUS-1 " 1480 UPDATE EXO beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_name "UPDATED ARO_name with EXO-1 " 395 UPDATE TLE beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; model_name; ARO_name "UPDATED model_name with blaF UPDATED ARO_name with blaF " 2803 UPDATE Mycobacterium tuberculosis thyA with mutation conferring resistance to para-aminosalicylic acid antibiotic resistant gene variant or mutant; determinant of aminosalicylate resistance; model_param "UPDATED param_value with 500 " 1928 UPDATE OXA-50 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_description "UPDATED ARO_description with OXA-50 is a beta-lactamase found in Pseudomonas aeruginosa. It confers decreased susceptibility to ampicillin and ticarcillin and, interestingly, to moxalactam and meropenem in P. aeruginosa but not in E. coli. Also confers resistance to piperacillin-tazobactam and cephalotin. " 1223 UPDATE viomycin phosphotransferase determinant of resistance to peptide antibiotics; antibiotic inactivation enzyme; ARO_name "UPDATED ARO_name with vph " 237 UPDATE BlaB beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_description; ARO_name "UPDATED ARO_description with This BlaB specific to Chryseobacterium meningosepticum mediates resistance against many beta-lactam antibiotics, notably penams and carbapenems. UPDATED ARO_name with Chryseobacterium meningosepticum BlaB " 1879 UPDATE AAC(3)-IIIa antibiotic inactivation enzyme; determinant of aminoglycoside resistance; model_param "UPDATED param_value with 450 " 2785 UPDATE Klebsiella pneumoniae OmpK37 protein modulating permeability to antibiotic; model_param "UPDATED param_value with 700 " 138 UPDATE Streptomyces lividans cml efflux pump complex or subunit conferring antibiotic resistance; determinant of phenicol resistance; ARO_description; ARO_category; ARO_name "UPDATED ARO_description with cmlR is a plasmid or chromosome-encoded chloramphenicol resistance determinant (putative transmembrane protein) that is found in Escherichia coli and Streptomyces lividans UPDATED category_aro_name with efflux pump complex or subunit conferring antibiotic resistance UPDATED category_aro_cvterm_id with 36298 UPDATED category_aro_accession with 3000159 UPDATED category_aro_description with Efflux proteins that pump antibiotic out of a cell to confer resistance. UPDATED ARO_name with Streptomyces lividans cmlR " 707 UPDATE AIM-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_description "UPDATED ARO_description with AIM-1 is an Ambler class B beta-lactamase that hydrolyzes most beta-lactams except aztreonam and ceftazidime. It was isolated from Pseudomonas aeruginosa and was the first subclass B3 mobile-elements encoded beta-lactamase discovered. " 1302 UPDATE tet34 protein(s) conferring antibiotic resistance via molecular bypass; antibiotic inactivation enzyme; determinant of tetracycline resistance; ARO_category "UPDATED category_aro_name with antibiotic inactivation enzyme UPDATED category_aro_cvterm_id with 36696 UPDATED category_aro_accession with 3000557 UPDATED category_aro_description with Enzyme that catalyzes the inactivation of an antibiotic resulting in resistance. Inactivation includes chemical modification, destruction, etc. " 1812 UPDATE KHM-1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_name "UPDATED ARO_name with KHM-1 " 49 UPDATE tsnr antibiotic target modifying enzyme; determinant of resistance to peptide antibiotics; ARO_description; model_sequences; model_name; ARO_name "UPDATED ARO_description with tsnR is a 23S ribosomal RNA methyltransferase that methylates adenosine-1067 to confer resistance to thiostrepton UPDATED fmax with 1158 UPDATED strand with + UPDATED accession with L39157.1 UPDATED fmin with 345 UPDATED sequence with GTGGCCAATCTTGACGTTATTGTCGACCGTTCCGACCCCGCGGTGCAGCGCATCGTCGATGTGACCAAGCATTCCCGGTCCGTCGTGCGAACGGTGCTGATCGAGGACATCGAGCCCCTGACGCAGAGCATCCGCGCCGGGGTCGAGTTCACCGAGGTCTACGGTCTCGACACCGTGCCGTTCCCGGGTGATCTGCTCGCCGCCTGCGAAAAGCGCGGAATTCGGGTGCGGCTGCTCTCCGCCGCGGTCGCGAATCAGGTTTTCAAGACCGAGAAGAAGCCCAAGGTCTTCGGTATCGCGAAGGTTCCGCCGGCCGGCCGTTTCGCCGACCTGGAGAGCCTTTCCGGCGATGTCGTCCTGCTCGACGGCGTGAAGATCGTCGGCAACATCGGCGCCATCGTGCGGACGCGTTCGGCGCTCGGCGCCGCCGGCATCGTCCTGGTCGACAGCGGCCTCGGCACCATCGCGGACCGCCGGCTCATCCGCGCCAGCCGCGGCTACGTGTTCTCCCTGCCGATCGTGCTCGCGACGCGCGACGAGGCGCTGGCCTTCTTCCGTGACGGCGGGATGCGGCCCGTGGTCTTCGAGGCGGACGGCAAGCTGTCCATCGGAGAGCTCGACGGCATCGACGAGCGGCTCGTGCTCGTGTTCGGCAGCGAGAAGACCGGCCCGTCGGGCGAGTTCGCCGGGGTCGCCACCGAGTCGGTGTCCATCCCGATGAACCCCGCCGCCGAGTCGCTCAACGTCTCGGTGTCGGCCGGCATCGCCCTGCACCGGCGGGCCCGCCGCAACCTCTCGCGCCCGCGCGGCTGA UPDATED NCBI_taxonomy_name with Streptomyces laurentii UPDATED NCBI_taxonomy_id with 39478 UPDATED NCBI_taxonomy_cvterm_id with 41352 UPDATED accession with AAA99931.1 UPDATED sequence with MANLDVIVDRSDPAVQRIVDVTKHSRSVVRTVLIEDIEPLTQSIRAGVEFTEVYGLDTVPFPGDLLAACEKRGIRVRLLSAAVANQVFKTEKKPKVFGIAKVPPAGRFADLESLSGDVVLLDGVKIVGNIGAIVRTRSALGAAGIVLVDSGLGTIADRRLIRASRGYVFSLPIVLATRDEALAFFRDGGMRPVVFEADGKLSIGELDGIDERLVLVFGSEKTGPSGEFAGVATESVSIPMNPAAESLNVSVSAGIALHRRARRNLSRPRG UPDATED model_name with tsnR UPDATED ARO_name with tsnR " 1942 UPDATE BJP-1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_name "UPDATED ARO_name with BJP-1 " 874 UPDATE AAC(1) antibiotic inactivation enzyme; determinant of aminoglycoside resistance; ARO_name "UPDATED ARO_name with AAC(1)-I " 1718 UPDATE DIM-1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_name "UPDATED ARO_name with DIM-1 " 2138 UPDATE NmcA beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_name "UPDATED ARO_name with NmcA " 871 UPDATE CGB-1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_name "UPDATED ARO_name with CGB-1 " 322 UPDATE FEZ-1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_name "UPDATED ARO_name with FEZ-1 " _version N/A N/A N/A N/A NEW: 1.2.1 , OLD: 1.2.0 2400 UPDATE oqxB efflux pump complex or subunit conferring antibiotic resistance; model_param "UPDATED param_value with 2000 " 1395 UPDATE Neisseria gonorrhoeae mutant porin PIB (por) with reduced permeability to antibiotic determinant of tetracycline resistance; antibiotic resistant gene variant or mutant; determinant of beta-lactam resistance; protein modulating permeability to antibiotic; ARO_description; ARO_name "UPDATED ARO_description with Mutant forms of the porin Por result in reduced permeability to antibiotics, particularly tetracyclines and beta-lactams. UPDATED ARO_name with Neisseria gonorrhoeae mutant porin PIB (por) with reduced permeability to antibiotics " 1677 UPDATE cepA beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_name "UPDATED ARO_name with cepA " 1393 UPDATE THIN-B beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_name "UPDATED ARO_name with THIN-B " 815 UPDATE GOB-1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_description; ARO_name "UPDATED ARO_description with GOB-1 confers resistance to cephalosporins in Elizabethkingia (Chryseobacterium) meningoseptica. UPDATED ARO_name with GOB-1 " 1294 UPDATE Sed1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_description; ARO_name "UPDATED ARO_description with Sed-1 is a chromosomal-encoded class A beta-lactamase identified in Citrobacter sedlakii. UPDATED ARO_name with Sed-1 " 753 UPDATE SMB-1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_name "UPDATED ARO_name with SMB-1 " 2279 UPDATE Listeria monocytogenes mprF antibiotic target modifying enzyme; gene altering cell wall charge; ARO_category "DELETED 37131 " 1237 UPDATE Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin determinant of rifamycin resistance; antibiotic resistant gene variant or mutant; antibiotic target replacement protein; ARO_category "UPDATED category_aro_name with antibiotic target replacement protein UPDATED category_aro_cvterm_id with 36520 UPDATED category_aro_accession with 3000381 UPDATED category_aro_description with Alternate proteins that have the same functions as other antibiotic target proteins, but are structurally different and thus resistant to antibiotics. These can replace the activity of other antibiotic-sensitive proteins in the presence of antibiotics. " 1338 UPDATE BLA1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_description; ARO_name "UPDATED ARO_description with Bla1 is a chromosomal-encoded beta-lactamase, found in Bacillus anthracis, which hydrolyzes penicillins. UPDATED ARO_name with Bla1 " 2281 UPDATE Brucella suis mprF antibiotic target modifying enzyme; gene altering cell wall charge; ARO_category "DELETED 37131 " 2282 UPDATE Clostridium perfringens mprF antibiotic target modifying enzyme; gene altering cell wall charge; ARO_category "DELETED 37131 " 2283 UPDATE Streptococcus agalactiae mprF antibiotic target modifying enzyme; gene altering cell wall charge; ARO_category "DELETED 37131 " 2819 UPDATE Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics antibiotic resistant gene variant or mutant; determinant of oxazolidinone resistance; ARO_category "UPDATED category_aro_name with antibiotic resistant gene variant or mutant UPDATED category_aro_cvterm_id with 35950 UPDATED category_aro_accession with 0000031 UPDATED category_aro_description with Resistance to antibiotics is often conferred by single nucleotide polymorphisms (SNPs) and other mutations in target genes. UPDATED category_aro_name with determinant of oxazolidinone resistance UPDATED category_aro_cvterm_id with 40403 UPDATED category_aro_accession with 3003747 UPDATED category_aro_description with Enzymes, other proteins or other gene products shown clinically to confer resistance to oxazolidinone (ie., linezolid) antibiotics. " 1109 UPDATE CAU-1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_name "UPDATED ARO_name with CAU-1 " 90 UPDATE Staphylococcus aureus rpoB mutants conferring resistance to rifampicin determinant of rifamycin resistance; antibiotic resistant gene variant or mutant; antibiotic target replacement protein; ARO_category "UPDATED category_aro_name with antibiotic target replacement protein UPDATED category_aro_cvterm_id with 36520 UPDATED category_aro_accession with 3000381 UPDATED category_aro_description with Alternate proteins that have the same functions as other antibiotic target proteins, but are structurally different and thus resistant to antibiotics. These can replace the activity of other antibiotic-sensitive proteins in the presence of antibiotics. " 222 UPDATE JOHN-1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_name "UPDATED ARO_name with JOHN-1 " 2831 UPDATE Nocardia rifampin resistant beta-subunit of RNA polymerase (rpoB2) determinant of rifamycin resistance; antibiotic resistant gene variant or mutant; antibiotic target replacement protein; ARO_name "UPDATED ARO_name with rpoB2 " _timestamp N/A N/A N/A N/A NEW: 2017-10-10T19:05:18+00:00 , OLD: 2017-08-30T14:13:02+00:00 1427 UPDATE acrD efflux pump complex or subunit conferring antibiotic resistance; model_param "UPDATED param_value with 1900 " 1282 UPDATE SIM-1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_name "UPDATED ARO_name with SIM-1 " 1558 UPDATE Bacillus subtilis mprF antibiotic target modifying enzyme; gene altering cell wall charge; ARO_category "DELETED 37131 " 1847 UPDATE emrB efflux pump complex or subunit conferring antibiotic resistance; model_param "UPDATED param_value with 900 " 943 UPDATE vanU determinant of resistance to glycopeptide antibiotics; protein(s) conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_description; ARO_id; ARO_accession; model_name; ARO_name "UPDATED ARO_description with vanUG is a vanG variant found in the vanG gene cluster. UPDATED ARO_id with 41417 UPDATED ARO_accession with 3004253 UPDATED model_name with vanUG UPDATED ARO_name with vanUG " 1460 UPDATE FosB3 antibiotic inactivation enzyme; determinant of fosfomycin resistance; model_param "UPDATED param_value with 250 " 1104 UPDATE acrB efflux pump complex or subunit conferring antibiotic resistance; model_param "UPDATED param_value with 1900 " 534 UPDATE vanV determinant of resistance to glycopeptide antibiotics; protein(s) conferring antibiotic resistance via molecular bypass; antibiotic resistance gene cluster, cassette, or operon; ARO_description; ARO_id; ARO_accession; model_name; ARO_name "UPDATED ARO_description with vanVB is a vanV variant found in the vanB gene cluster. It is found in some but not all vanB operons in E. faecalis, suggesting the existence of varied gene compositions in vanB operons. UPDATED ARO_id with 41418 UPDATED ARO_accession with 3004254 UPDATED model_name with vanVB UPDATED ARO_name with vanVB " 2752 UPDATE ANT(3'')-IIa antibiotic inactivation enzyme; determinant of aminoglycoside resistance; model_param "UPDATED param_value with 450 " 2753 UPDATE HMB-1 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_name "UPDATED ARO_name with HMB-1 " 1687 UPDATE CEPH-A3 antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_name "UPDATED ARO_name with cphA3 " 299 UPDATE CepS beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_description; ARO_name "UPDATED ARO_description with CEPS is a typical class C cephalosporinase found in Aeromonas sobria, first isolated from strain 163a. UPDATED ARO_name with CepS " 1721 UPDATE Mycobacterium leprae folP with mutation conferring resistance to dapsone antibiotic resistant gene variant or mutant; ARO_category "DELETED 36547 " 2375 UPDATE Rm3 beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_name "UPDATED ARO_name with Rm3 " 538 UPDATE Enterobacter cloacae rob efflux pump complex or subunit conferring antibiotic resistance; protein(s) and two-component regulatory system modulating antibiotic efflux; model_param "UPDATED param_value with 500 " 1381 UPDATE CcrA beta-lactamase antibiotic inactivation enzyme; determinant of beta-lactam resistance; ARO_description; ARO_name "UPDATED ARO_description with This CcrA beta-lactamases is found in Bacteroides fragilis. UPDATED ARO_name with CcrA " 431 UPDATE Escherichia coli marR mutant conferring antibiotic resistance efflux pump complex or subunit conferring antibiotic resistance; antibiotic resistant gene variant or mutant; protein(s) and two-component regulatory system modulating antibiotic efflux; model_param "UPDATED 8206 with R58L UPDATED 8206 with R58L " 2830 DELETE DnaA antibiotic target protection protein; determinant of rifamycin resistance; N/A N/A 2840 ADD NPS-1 antibiotic inactivation enzyme; determinant of beta-lactam resistance; N/A N/A 2839 ADD GOB-18 antibiotic inactivation enzyme; determinant of beta-lactam resistance; N/A N/A 2838 ADD MCR-1.2 determinant of polymyxin resistance; gene altering cell wall charge; N/A N/A 2837 ADD APH(2'')-If antibiotic inactivation enzyme; determinant of aminoglycoside resistance; N/A N/A 2836 ADD Bla2 antibiotic inactivation enzyme; determinant of beta-lactam resistance; N/A N/A 2835 ADD PatA-PatB efflux pump complex or subunit conferring antibiotic resistance; N/A N/A 2834 ADD Mycobacterium tuberculosis iniB with mutation conferring resistance to ethambutol efflux pump complex or subunit conferring antibiotic resistance; antibiotic resistant gene variant or mutant; determinant of resistance to polyamine antibiotics; N/A N/A