determinant of streptogramin resistance

Accession ARO:3000240
DefinitionEzymes, other proteins or other gene products shown clinically to confer resistance to streptogramin antibiotics.
Drug Classstreptogramin antibiotic
Classification2 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ confers_resistance_to_drug_class streptogramin antibiotic [Drug Class]
+ determinant of antibiotic resistance
4 ontology terms | Show

Singh KV, et al. 2002. Antimicrob Agents Chemother 46(6): 1845-1850. An Enterococcus faecalis ABC homologue (Lsa) is required for the resistance of this species to clindamycin and quinupristin-dalfopristin. (PMID 12019099)

Allignet J, et al. 1992. Gene 117(1): 45-51. Sequence of a staphylococcal plasmid gene, vga, encoding a putative ATP-binding protein involved in resistance to virginiamycin A-like antibiotics. (PMID 1644314)

Allignet J and El Solh N. 1997. Gene 202(1-2): 133-138. Characterization of a new staphylococcal gene, vgaB, encoding a putative ABC transporter conferring resistance to streptogramin A and related compounds. (PMID 9427556)