thiorphan [Adjuvant]

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Accession ARO:3007302
DefinitionThiorphan is the active metabolite of the antidieuretic drug racecadotril. It has shown inhibitory activity against various metallo-beta-lactamases.
Classification5 ontology terms | Show
Parent Term(s)4 ontology terms | Show
+ is_small_molecule_inhibitor NDM-1
+ is_small_molecule_inhibitor IMP-7
+ is_small_molecule_inhibitor VIM-1
+ unclassified metallo-beta-lactamase inhibitor
Publications

González-Bello C, et al. 2020. J Med Chem 63(5):1859-1881 β-Lactamase Inhibitors To Restore the Efficacy of Antibiotics against Superbugs. (PMID 31663735)