The Comprehensive Antibiotic Resistance Database

A bioinformatic database of resistance genes, their products and associated phenotypes.

6561 Ontology Terms, 5000 Reference Sequences, 1929 SNPs, 2963 Publications, 5046 AMR Detection Models

Resistome predictions: 263 pathogens, 16719 chromosomes, 2675 genomic islands, 33860 plasmids, 136704 WGS assemblies, 285146 alleles

CARD Bait Capture Platform 1.0.0 | State of the CARD 2021 Presentations & Demonstrations


The CARD is a rigorously curated collection of characterized, peer-reviewed resistance determinants and associated antibiotics, organized by the Antibiotic Resistance Ontology (ARO) and AMR gene detection models.


The CARD includes tools for analysis of molecular sequences, including BLAST and the Resistance Gene Identifier (RGI) software for prediction of resistome based on homology and SNP models.


CARD data and ontologies can be downloaded in a number of formats. RGI software is available as a command-line tool. CARD Bait Capture Platform sequences and protocol available for download.

Resistomes, Variants, & Prevalence

Computer-generated resistome predictions for 263 important pathogens. Includes sequence variants beyond those reported in the scientific literature, as well as prevalence statistics for AMR genes among pathogens, genomes, and plasmids.


The CARD:Live project collects pathogen identification, MLST, AMR gene list, date, and geographical region for genome sequences submitted to RGI online, providing a dynamic view of antibiotic resistant isolates being analyzed around the world.