The CARD:Live project collects pathogen identification, MLST, AMR gene list (RGI Perfect & Strict hits only), date, and geographical region for genome sequences submitted to RGI online, providing a dynamic view of antibiotic resistant isolates being analyzed around the world. All information collected is based on consent and no sequence information is retained. We ask RGI users to please consider sharing their AMR metadata so we can build and share a dynamic data set of antibiotic resistance pathogens from around the globe.
Currently, CARD:Live is running as a pilot project to assess community engagement and as a software test. As data accumulates, we will pilot geotemporal plots of AMR gene frequencies across the globe, including downloadable summary data.
| Pathogen ID | Citrobacter freundii |
| MLST | 88 |
| Region | Latin America and the Caribbean |
| Timestamp | 2020-03-31 09:01:01.318835 |
| Hit Criteria | CARD Bitscore Cut Off | Hit Bitscore | AMR Gene | ARO Accession | Percent Identity | Percentage Length of Reference Sequence | Model ID | Model Type | SNPs in Best Hit ARO | Other SNPs | Drug Class | Resistance Mechanism | AMR Gene Family | CARD Kmer Prediction |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Strict | 400 | 459.9 | QnrB10 | 3002724 | 98.67 | 100 | 139 | protein homolog model | n/a | n/a | fluoroquinolone antibiotic | antibiotic target protection | quinolone resistance protein (qnr) | Citrobacter freundii (plasmid) |
| Perfect | 500 | 544.3 | NDM-1 | 3000589 | 100 | 100 | 783 | protein homolog model | n/a | n/a | carbapenem; cephalosporin; cephamycin; penam | antibiotic inactivation | NDM beta-lactamase | Citrobacter freundii (chromosome or plasmid) |
| Strict | 1500 | 1538.5 | Escherichia coli gyrA conferring resistance to fluoroquinolones | 3003294 | 91.09 | 100.34 | 1545 | protein variant model | S83I | n/a | fluoroquinolone antibiotic | antibiotic target alteration | fluoroquinolone resistant gyrA | Citrobacter freundii (chromosome) |
Resistome and CARD Kmer predictions produced by the Resistome Gene Identifier, Pathogen Identification predicted by LMAT, MLST predicted by PubMLST, Geographical region supplied by User (following United Nations, Department of Economic and Social Affairs, Statistics Division).
