Staphylococcus aureus

O'Brien FG, et al. 2002. J Antimicrob Chemother 50(3): 313-321. Genetic characterization of the fusidic acid and cadmium resistance determinants of Staphylococcus aureus plasmid pUB101. (PMID 12205055)

Firth N, et al. 1993. Gene 136(1-2): 13-25. Analysis of a transfer region from the staphylococcal conjugative plasmid pSK41. (PMID 8293996)

Weigel LM, et al. 2003. Science 302(5650): 1569-1571. Genetic analysis of a high-level vancomycin-resistant isolate of Staphylococcus aureus. (PMID 14645850)

Bjorland J, et al. 2003. Antimicrob Agents Chemother 47(10): 3046-3052. Novel plasmid-borne gene qacJ mediates resistance to quaternary ammonium compounds in equine Staphylococcus aureus, Staphylococcus simulans, and Staphylococcus intermedius. (PMID 14506007)

Anthonisen IL, et al. 2002. Antimicrob Agents Chemother 46(11): 3606-3612. Organization of the antiseptic resistance gene qacA and Tn552-related beta-lactamase genes in multidrug- resistant Staphylococcus haemolyticus strains of animal and human origins. (PMID 12384372)

Needham C, et al. 1995. Plasmid 34(3): 198-205. The staphylococcal insertion sequence IS257 is active. (PMID 8825372)

Khan SA and Novick RP. 1982. J Bacteriol 149(2): 642-649. Structural analysis of plasmid pSN2 in Staphylococcus aureus: no involvement in enterotoxin B production. (PMID 7056699)

Horinouchi S and Weisblum B. 1982. J Bacteriol 150(2): 815-825. Nucleotide sequence and functional map of pC194, a plasmid that specifies inducible chloramphenicol resistance. (PMID 6950931)

Baba T, et al. 2002. Lancet 359(9320): 1819-1827. Genome and virulence determinants of high virulence community-acquired MRSA. (PMID 12044378)

Netz DJ, et al. 2001. J Mol Biol 311(5): 939-949. Molecular characterisation of aureocin A70, a multi-peptide bacteriocin isolated from Staphylococcus aureus. (PMID 11531330)

Yamaguchi T, et al. 2001. Infect Immun 69(12): 7760-7771. Complete nucleotide sequence of a Staphylococcus aureus exfoliative toxin B plasmid and identification of a novel ADP-ribosyltransferase, EDIN-C. (PMID 11705958)

Caryl JA and O'Neill AJ. 2009. Plasmid 62(1): 35-38. Complete nucleotide sequence of pGO1, the prototype conjugative plasmid from the Staphylococci. (PMID 19298835)

Nakaminami H, et al. 2008. Plasmid 60(2): 108-117. Characterization of the pTZ2162 encoding multidrug efflux gene qacB from Staphylococcus aureus. (PMID 18539327)

Gentry DR, et al. 2008. Antimicrob Agents Chemother 52(12): 4507-4509. Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus. (PMID 18838584)

Kuroda M, et al. 2001. Lancet 357(9264): 1225-1240. Whole genome sequencing of meticillin-resistant Staphylococcus aureus. (PMID 11418146)

Berg T, et al. 1998. J Bacteriol 180(17): 4350-4359. Complete nucleotide sequence of pSK41: evolution of staphylococcal conjugative multiresistance plasmids. (PMID 9721269)

Herzberg O. 1991. J Mol Biol 217(4): 701-719. Refined crystal structure of beta-lactamase from Staphylococcus aureus PC1 at 2.0 A resolution. (PMID 2005620)

Herzberg O, et al. 1991. Biochemistry 30(39): 9503-9509. Structural basis for the inactivation of the P54 mutant of beta-lactamase from Staphylococcus aureus PC1. (PMID 1892849)

Chen CC, et al. 1993. J Mol Biol 234(1): 165-178. Structure of a phosphonate-inhibited beta-lactamase. An analog of the tetrahedral transition state/intermediate of beta-lactam hydrolysis. (PMID 8230196)

Herzberg O and Moult J. 1987. Science 236(4802): 694-701. Bacterial resistance to beta-lactam antibiotics: crystal structure of beta-lactamase from Staphylococcus aureus PC1 at 2.5 A resolution. (PMID 3107125)

Banerjee S, et al. 1998. Biochemistry 37(10): 3286-3296. Role of the omega-loop in the activity, substrate specificity, and structure of class A beta-lactamase. (PMID 9521648)

Zawadzke LE, et al. 1995. Protein Eng 8(12): 1275-1285. An engineered Staphylococcus aureus PC1 beta-lactamase that hydrolyses third-generation cephalosporins. (PMID 8869640)

Moult J, et al. 1985. Biochem J 225(1): 167-176. The crystal structure of beta-lactamase from Staphylococcus aureus at 0.5 nm resolution. (PMID 2983660)

Chen CC and Herzberg O. 1992. J Mol Biol 224(4): 1103-1113. Inhibition of beta-lactamase by clavulanate. Trapped intermediates in cryocrystallographic studies. (PMID 1569569)

Allignet J, et al. 1993. Gene 130(1): 91-98. Sequence of a staphylococcal gene, vat, encoding an acetyltransferase inactivating the A-type compounds of virginiamycin-like antibiotics. (PMID 8344533)

Patti JM, et al. 1992. J Biol Chem 267(7): 4766-4772. Molecular characterization and expression of a gene encoding a Staphylococcus aureus collagen adhesin. (PMID 1311320)

Ito T, et al. 2003. Drug Resist Updat 6(1): 41-52. Insights on antibiotic resistance of Staphylococcus aureus from its whole genome: genomic island SCC. (PMID 12654286)

Ito T, et al. 1999. Antimicrob Agents Chemother 43(6): 1449-1458. Cloning and nucleotide sequence determination of the entire mec DNA of pre-methicillin-resistant Staphylococcus aureus N315. (PMID 10348769)

Allignet J, et al. 1988. Plasmid 20(3): 271-275. Nucleotide sequence of a staphylococcal plasmid gene, vgb, encoding a hydrolase inactivating the B components of virginiamycin-like antibiotics. (PMID 3149758)

Horinouchi S and Weisblum B. 1980. Proc Natl Acad Sci U S A 77(12): 7079-7083. Posttranscriptional modification of mRNA conformation: mechanism that regulates erythromycin-induced resistance. (PMID 6938954)

Brisson-Noel A, et al. 1988. J Biol Chem 263(31): 15880-15887. Inactivation of lincosaminide antibiotics in Staphylococcus. Identification of lincosaminide O-nucleotidyltransferases and comparison of the corresponding resistance genes. (PMID 2846528)

Gray GS and Fitch WM. 1983. Mol Biol Evol 1(1): 57-66. Evolution of antibiotic resistance genes: the DNA sequence of a kanamycin resistance gene from Staphylococcus aureus. (PMID 6100986)

Gryczan TJ, et al. 1980. Nucleic Acids Res 8(24): 6081-6097. Conformational alteration of mRNA structure and the posttranscriptional regulation of erythromycin-induced drug resistance. (PMID 6162157)

Allignet J, et al. 1992. Gene 117(1): 45-51. Sequence of a staphylococcal plasmid gene, vga, encoding a putative ATP-binding protein involved in resistance to virginiamycin A-like antibiotics. (PMID 1644314)

Lina G, et al. 2006. Clin Microbiol Infect 12(12): 1175-1184. Staphylococcal chromosome cassette evolution in Staphylococcus aureus inferred from ccr gene complex sequence typing analysis. (PMID 17121623)

Truong-Bolduc QC, et al. 2005. J Bacteriol 187(7): 2395-2405. MgrA is a multiple regulator of two new efflux pumps in Staphylococcus aureus. (PMID 15774883)

Yoshida H, et al. 1990. J Bacteriol 172(12): 6942-6949. Nucleotide sequence and characterization of the Staphylococcus aureus norA gene, which confers resistance to quinolones. (PMID 2174864)

Ito T, et al. 2001. Antimicrob Agents Chemother 45(5): 1323-1336. Structural comparison of three types of staphylococcal cassette chromosome mec integrated in the chromosome in methicillin-resistant Staphylococcus aureus. (PMID 11302791)

Matsuoka M, et al. 2001. Antimicrob Agents Chemother 46(1): 211-215. New erm Gene in Staphylococcus aureus clinical isolates. (PMID 11751136)

Jonsson K, et al. 1991. Eur J Biochem 202(3): 1041-1048. Two different genes encode fibronectin binding proteins in Staphylococcus aureus. The complete nucleotide sequence and characterization of the second gene. (PMID 1837266)

Hiramatsu K, et al. 1992. FEBS Lett 298(2-3): 133-136. Molecular cloning and nucleotide sequence determination of the regulator region of mecA gene in methicillin-resistant Staphylococcus aureus (MRSA). (PMID 1544435)

Allignet J and El Solh N. 1997. Gene 202(1-2): 133-138. Characterization of a new staphylococcal gene, vgaB, encoding a putative ABC transporter conferring resistance to streptogramin A and related compounds. (PMID 9427556)

Matsuoka M, et al. 1998. FEMS Microbiol Lett 167(2): 221-227. A plasmid that encodes three genes for resistance to macrolide antibiotics in Staphylococcus aureus. (PMID 9809423)

Horinouchi S and Weisblum B. 1982. J Bacteriol 150(2): 804-814. Nucleotide sequence and functional map of pE194, a plasmid that specifies inducible resistance to macrolide, lincosamide, and streptogramin type B antibodies. (PMID 6279574)

Loeza-Lara PD, et al. 2004. Plasmid 52(1): 48-56. pBMSa1, a plasmid from a dairy cow isolate of Staphylococcus aureus, encodes a lincomycin resistance determinant and replicates by the rolling-circle mechanism. (PMID 15212891)

Chen L, et al. 2010. Antimicrob Agents Chemother 54(8): 3347-3354. Identification of a novel transposon (Tn6072) and a truncated staphylococcal cassette chromosome mec element in methicillin-resistant Staphylococcus aureus ST239. (PMID 20479198)

Hodgson JE, et al. 1994. Antimicrob Agents Chemother 38(5): 1205-1208. Molecular characterization of the gene encoding high-level mupirocin resistance in Staphylococcus aureus J2870. (PMID 8067768)

Murphy E. 1985. Mol Gen Genet 200(1): 33-39. Nucleotide sequence of a spectinomycin adenyltransferase AAD(9) determinant from Staphylococcus aureus and its relationship to AAD(3) (9). (PMID 2993813)

Shore AC, et al. 2011. Antimicrob Agents Chemother 55(8): 3765-3773. Detection of staphylococcal cassette chromosome mec type XI carrying highly divergent mecA, mecI, mecR1, blaZ, and ccr genes in human clinical isolates of clonal complex 130 methicillin-resistant Staphylococcus aureus. (PMID 21636525)

McLaughlin JR, et al. 1981. J Biol Chem 256(21): 11283-11291. Unique features in the ribosome binding site sequence of the gram-positive Staphylococcus aureus beta-lactamase gene. (PMID 6793593)

Chan PT. 1986. Nucleic Acids Res 14(14): 5940. Nucleotide sequence of the Staphylococcus aureus PC1 beta-lactamase gene. (PMID 3488540)

Kwong SM, et al. 2008. Microbiology 154(PT 10): 3084-3094. Analysis of the pSK1 replicon, a prototype from the staphylococcal multiresistance plasmid family. (PMID 18832314)

Simpson AE, et al. 2003. J Bacteriol 185(7): 2143-2152. A single gene on the staphylococcal multiresistance plasmid pSK1 encodes a novel partitioning system. (PMID 12644483)

Firth N, et al. 2000. J Bacteriol 182(8): 2170-2178. Replication of staphylococcal multiresistance plasmids. (PMID 10735859)

Rouch DA, et al. 1989. Mol Microbiol 3(2): 161-175. Trimethoprim resistance transposon Tn4003 from Staphylococcus aureus encodes genes for a dihydrofolate reductase and thymidylate synthetase flanked by three copies of IS257. (PMID 2548057)

Grkovic S, et al. 2003. Microbiology 149(PT 3): 785-794. Stable low-copy-number Staphylococcus aureus shuttle vectors. (PMID 12634346)

Jensen SO, et al. 2010. Plasmid 64(3): 135-142. Analysis of the prototypical Staphylococcus aureus multiresistance plasmid pSK1. (PMID 20547176)

Rouch DA, et al. 1987. J Gen Microbiol 133(11): 3039-3052. The aacA-aphD gentamicin and kanamycin resistance determinant of Tn4001 from Staphylococcus aureus: expression and nucleotide sequence analysis. (PMID 2833561)

Byrne ME, et al. 1989. Gene 81(2): 361-367. Nucleotide sequence analysis of IS256 from the Staphylococcus aureus gentamicin-tobramycin-kanamycin-resistance transposon Tn4001. (PMID 2553542)

Rouch DA, et al. 1990. Mol Microbiol 4(12): 2051-2062. Efflux-mediated antiseptic resistance gene qacA from Staphylococcus aureus: common ancestry with tetracycline- and sugar-transport proteins. (PMID 2089219)

Paulsen IT, et al. 1994. Gene 141(1): 109-114. Characterisation of sin, a potential recombinase-encoding gene from Staphylococcus aureus. (PMID 8163161)

Jamrozy DM, et al. 2014. J Antimicrob Chemother 69(5): 1193-1196. Identification of a novel plasmid-associated spectinomycin adenyltransferase gene spd in methicillin-resistant Staphylococcus aureus ST398 isolated from animal and human sources. (PMID 24402501)

Li B, et al. 2013. J Antimicrob Chemother 68(6): 1251-1255. Detection and new genetic environment of the pleuromutilin-lincosamide-streptogramin A resistance gene lsa(E) in methicillin-resistant Staphylococcus aureus of swine origin. (PMID 23386262)

Cardoso M, et al. 1992. J Appl Bacteriol 72(4): 289-293. Nucleotide sequence and structural relationships of a chloramphenicol acetyltransferase encoded by the plasmid pSCS6 from Staphylococcus aureus. (PMID 1517170)

Wang PZ, et al. 1993. EMBO J 12(1): 45-52. Origin recognition specificity in pT181 plasmids is determined by a functionally asymmetric palindromic DNA element. (PMID 8428593)

Projan SJ, et al. 1985. Mol Gen Genet 199(3): 452-464. Comparative sequence and functional analysis of pT181 and pC221, cognate plasmid replicons from Staphylococcus aureus. (PMID 2993795)

Bruckner R and Matzura H. 1985. EMBO J 4(9): 2295-2300. Regulation of the inducible chloramphenicol acetyltransferase gene of the Staphylococcus aureus plasmid pUB112. (PMID 3865770)

Schwarz S, et al. 1991. Antimicrob Agents Chemother 35(8): 1551-1556. Nucleotide sequence and phylogeny of a chloramphenicol acetyltransferase encoded by the plasmid pSCS7 from Staphylococcus aureus. (PMID 1929326)

Smith MC and Thomas CD. 2004. J Bacteriol 186(11): 3363-3373. An accessory protein is required for relaxosome formation by small staphylococcal plasmids. (PMID 15150221)

Bhakta M, et al. 2003. Curr Microbiol 46(6): 413-417. Identification and characterization of a shuttle plasmid with antibiotic resistance gene from Staphylococcus aureus. (PMID 12732947)

Lozano C, et al. 2012. J Antimicrob Chemother 67(12): 2804-2808. Genetic environment and location of the lnu(A) and lnu(B) genes in methicillin-resistant Staphylococcus aureus and other staphylococci of animal and human origin. (PMID 22899804)

Catchpole I, et al. 1988. J Gen Microbiol 134(3): 697-709. The nucleotide sequence of Staphylococcus aureus plasmid pT48 conferring inducible macrolide-lincosamide-streptogramin B resistance and comparison with similar plasmids expressing constitutive resistance. (PMID 3141573)

Murphy E, et al. 1985. EMBO J 4(12): 3357-3365. Transposon Tn554: complete nucleotide sequence and isolation of transposition-defective and antibiotic-sensitive mutants. (PMID 3004956)

Kaatz GW, et al. 2005. Antimicrob Agents Chemother 49(5): 1857-1864. Multidrug resistance in Staphylococcus aureus due to overexpression of a novel multidrug and toxin extrusion (MATE) transport protein. (PMID 15855507)

Nakaminami H, et al. 2010. Antimicrob Agents Chemother 54(10): 4107-4111. Fluoroquinolone efflux by the plasmid-mediated multidrug efflux pump QacB variant QacBIII in Staphylococcus aureus. (PMID 20660673)

Alam MM, et al. 2003. Microb Drug Resist 9(2): 109-121. Analysis on distribution and genomic diversity of high-level antiseptic resistance genes qacA and qacB in human clinical isolates of Staphylococcus aureus. (PMID 12820795)

Sekiguchi J, et al. 2005. Antimicrob Agents Chemother 49(9): 3948-3951. Cloning and characterization of a novel trimethoprim-resistant dihydrofolate reductase from a nosocomial isolate of Staphylococcus aureus CM.S2 (IMCJ1454). (PMID 16127079)

Tanimoto K, et al. 2002. J Bacteriol 184(20): 5800-5804. Analysis of the conjugal transfer system of the pheromone-independent highly transferable Enterococcus plasmid pMG1: identification of a tra gene (traA) up-regulated during conjugation. (PMID 12270839)