phosphonoacetaldehyde methyltransfererase

Accession ARO:3000500
DefinitionThe enzyme responsible for converting phosphonoacetaldehyde to (S)-2-/nhydroxypropylphosphonic acid (S-HPP) via an anionic methyl attack, which also reduces the aldehyde to an alcohol.
Classification1 ontology terms | Show
Parent Term(s)1 ontology terms | Show

Higgins LJ, et al. 2005. Nature 437(7060): 838-844. Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme. (PMID 16015285)

Kuzuyama T, et al. 1992. J Antibiot (Tokyo) 45(11): 1812-1814. Studies on the biosynthesis of fosfomycin. 4. The biosynthetic origin of the methyl group of fosfomycin. (PMID 1468993)