fosmidomycin [Drug Class]

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Accession ARO:3000758
DefinitionFosmidomycin is an inhibitor of 1-deoxy-D-xylulose 5-phosphate reductoisomerase, an enzyme in the non-mevalonate pathway for isoprenoid synthesis. It is active against enterobacteria, but not against Gram-positive bacteria or anaerobes.
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Publications

Jomaa H, et al. 1999. Science 285(5433): 1573-1576. Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs. (PMID 10477522)