Ontology | CARD's Antibiotic Resistance Ontology |
Accession | ARO:3003462 |
Definition | kasA is a ketoacyl acyl carrier protein synthase that catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. It is involved in elongation of fatty acids intermediate in the biosynthetic pathway of mycolic acids. |
Drug Class | isoniazid-like antibiotic |
Resistance Mechanism | antibiotic target alteration |
Classification | 6 ontology terms | Show |
Parent Term(s) | 3 ontology terms | Show + antibiotic resistant gene variant or mutant + derives_from antibiotic sensitive kasA + confers_resistance_to_drug_class isoniazid-like antibiotic [Drug Class] |
Sub-Term(s) | 1 ontology terms | Show |
Publications | Lee AS, et al. 1999. Antimicrob Agents Chemother 43(8): 2087-2089. Contribution of kasA analysis to detection of isoniazid-resistant Mycobacterium tuberculosis in Singapore. (PMID 10428945) |
Curator | Description | Most Recent Edit |
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