Accession VIRO:0000093
DefinitionHBL-L1 is a component of Hemolysin BL, a membrane-lytic toxin from Bacillus cereus. HBL-B is the only protein able to associate productively with the cell membrane, and this binding is followed by the ordered recruitment of first L1 and then L2.The membrane-associated HBL components form a membrane attack complex that causes lysis by a colloid osmotic mechanism.
Classification10 ontology terms | Show
Parent Term(s)2 ontology terms | Show

Beecher DJ, et al. 1997. J. Biol. Chem. 272(1):233-9 Tripartite hemolysin BL from Bacillus cereus. Hemolytic analysis of component interactions and a model for its characteristic paradoxical zone phenomenon. (PMID 8995253)

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