nonhemolytic enterotoxin

Accession VIRO:0000096
Synonym(s)Nhe
DefinitionNonhemolytic enterotoxin (Nhe) from Bacillus cereus is a tripartite pore-forming toxin that require the combined action of the three proteins a cytolytic protein NheA, and two binding components NheB and NheC. Nhe possess hemolytic, cytotoxic, dermonecrotic, and vascular permeability activities.
Classification4 ontology terms | Show
Parent Term(s)2 ontology terms | Show
Sub-Term(s)
3 ontology terms | Show
+ NheA part_of
+ NheB part_of
+ NheC part_of
Publications

Fagerlund A, et al. 2008. Microbiology (Reading, Engl.) 154(Pt 3):693-704 Bacillus cereus Nhe is a pore-forming toxin with structural and functional properties similar to the ClyA (HlyE, SheA) family of haemolysins, able to induce osmotic lysis in epithelia. (PMID 18310016)