cytotoxic necrotizing factor 1

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Accession VIRO:0000130
DefinitionCytotoxic necrotizing factor 1 is a toxin expressed by certain uropathogenic and neonatal meningitis-causing strains of E. coli. It induces the formation of actin stress fibers and membrane ruffling, necrosis
Classification3 ontology terms | Show
Parent Term(s)1 ontology terms | Show

Doye A, et al. 2002. Cell 111(4):553-64 CNF1 exploits the ubiquitin-proteasome machinery to restrict Rho GTPase activation for bacterial host cell invasion. (PMID 12437928)

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