insertion mutation

Accession MO:0000040
DefinitionAn AMR detection model parameter to describe a set of mapped insertion mutations. An insertion mutation refers to the addition of one or more nucleotides to a DNA strand. In publications, insertion mutations may be reported in peptide or in nucleotide format. Insertions not of a multiple of 3 cause frameshifts in the nucleotide open reading frame. However, the insertion mutation parameter only refers to insertions which modify the peptide sequence and/or change its function, but do not result in premature termination or functional protein knockout (see: frameshift mutation, which covers these cases).
Classification1 ontology terms | Show
Parent Term(s)1 ontology terms | Show
2 ontology terms | Show