Accession VIRO:0000351
Synonym(s)type vi secretion exported 3
DefinitionA toxic effector protein secreted by the type VI secretion system of Pseudomonas aeruginosa responsible for degrading the peptidoglycan cell wall of Gram-negative bacteria. Tse3 is secreted into the periplasm and hydrolyses the bond between the N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues of the glycan backbone.
Classification6 ontology terms | Show
Parent Term(s)2 ontology terms | Show

Striebel HM, et al. 1996. Gene 172(1):41-6 Cloning and characterization of the MamI restriction-modification system from Microbacterium ammoniaphilum in Escherichia coli. (PMID 8654988)

Hood RD, et al. 2010. Cell Host Microbe 7(1):25-37 A type VI secretion system of Pseudomonas aeruginosa targets a toxin to bacteria. (PMID 20114026)

Russell AB, et al. 2011. Nature 475(7356):343-7 Type VI secretion delivers bacteriolytic effectors to target cells. (PMID 21776080)

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