delamanid [Antibiotic]

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Accession ARO:3004490
Synonym(s)deltyba
DefinitionA novel nitroimidazole antibiotic for treating Mycobacterium tuberculosis infection. Delamanid inhibits bacterial cell wall growth by mycolic acid synthesis disruption and is particularly effective in combination therapies against multidrug-resistant tuberculosis.
SMILESC[C@]1(COc2ccc(N3CCC(Oc4ccc(OC(F)(F)F)cc4)CC3)cc2)Cn2cc([N+](=O)[O-])nc2O1
PubChem6480466
ChEMBLCHEMBL218650
ChEBI134742
CAS681492-22-8
Drug Classnitroimidazole antibiotic
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
Sub-Term(s)
2 ontology terms | Show
Publications

Xavier AS, et al. 2014. J Pharmacol Pharmacother 5(3):222-4 Delamanid: A new armor in combating drug-resistant tuberculosis. (PMID 25210407)

Curator Acknowledgements
Curator Description Most Recent Edit