Ace (toxin)

Accession VIRO:0000455
Synonym(s)Accessory cholera enterotoxin
DefinitionAccessory cholera enterotoxin (Ace) secreted by Vibrio cholerae strains. Ace activates chloride channels stimulating chloride/bicarbonate transport that augments fluid secretion resulting in diarrhea.
Classification4 ontology terms | Show
Parent Term(s)2 ontology terms | Show

Chatterjee T, et al. 2015. PLoS ONE 10(11):e0141283 Effects of Small Molecule Calcium-Activated Chloride Channel Inhibitors on Structure and Function of Accessory Cholera Enterotoxin (Ace) of Vibrio cholerae. (PMID 26540279)

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