Ornibactin

Accession VIRO:0000540
DefinitionA linear tetrapeptide siderophore possessing two hydroxamate and alpha-hydroxycarboxylate with a 1-ornithine-d-hydroxyaspartate-1-serine-1-ornithine backbone. Ornibactin (along with pyochelin) is present mostly in Burkholderia spp. under iron-limiting conditions. Production of both siderophores has been correlated with morbity and mortality in CD patients.
Classification6 ontology terms | Show
Parent Term(s)1 ontology terms | Show
Sub-Term(s)
15 ontology terms | Show
Publications

Agnoli K, et al. 2006. J. Bacteriol. 188(10):3631-44 The ornibactin biosynthesis and transport genes of Burkholderia cenocepacia are regulated by an extracytoplasmic function sigma factor which is a part of the Fur regulon. (PMID 16672617)

Holden MT, et al. 2008. J Bacteriol 191(1): 261-277. The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of cystic fibrosis patients. (PMID 18931103)

Curator Acknowledgements
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