antibiotic resistant polyketide synthase genes [AMR Gene Family]

Accession ARO:3005002
DefinitionGenes ppsA-E constitute an operon encoding enzymes involved in the biosynthesis of phthiocerol dimycocerosate and other lipids in Mycobacterium tuberculosis. Mutations within this region can result in resistance to pyrazinamide.
Drug Classpyrazine antibiotic
Resistance Mechanismantibiotic target alteration
Classification6 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ antibiotic resistant gene variant or mutant
+ confers_resistance_to_drug_class pyrazine antibiotic [Drug Class]
3 ontology terms | Show