antifungal-resistant beta-1,3-D-glucan synthase

Accession ARO:3007545
DefinitionFungal beta-1,3-D-glucan synthase enzymes which include mutations to confer resistance to antifungal drug compounds.
Resistance Mechanismantibiotic target alteration
Classification5 ontology terms | Show
Parent Term(s)1 ontology terms | Show
1 ontology terms | Show

Garcia-Effron G, et al. 2009. Antimicrob Agents Chemother 53(9):3690-9 Effect of Candida glabrata FKS1 and FKS2 mutations on echinocandin sensitivity and kinetics of 1,3-beta-D-glucan synthase: implication for the existing susceptibility breakpoint. (PMID 19546367)