fungal uracil phosphoribosyltransferase [AMR Gene Family]

Accession ARO:3007556
DefinitionFungal uracil phosphoribosyltransferases which include mutations to confer resistance to 5-flucytosine antibiotic.
Drug Classpyrimidine antifungal drug
Resistance Mechanismantibiotic target alteration
Classification6 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ antibiotic resistant gene variant or mutant
+ confers_resistance_to_drug_class pyrimidine antifungal drug [Drug Class]
2 ontology terms | Show

Hope WW, et al. 2004. Antimicrob Agents Chemother 48(11):4377-86 Molecular mechanisms of primary resistance to flucytosine in Candida albicans. (PMID 15504867)