antibiotic resistant Rv0678

Accession ARO:3007672
DefinitionRv0678 encodes a transcription factor which negatively regulates the expression of the mmpS5/L5 efflux pump.
Resistance Mechanismantibiotic target alteration
Classification5 ontology terms | Show
Parent Term(s)1 ontology terms | Show
1 ontology terms | Show
+ bedaquiline resistant Rv0678 [AMR Gene Family]

Otum CC, et al. 2023. Sci Rep 13(1):9212 Site-directed mutagenesis of Mycobacterium tuberculosis and functional validation to investigate potential bedaquiline resistance-causing mutations. (PMID 37280265)