ANT(9) [AMR Gene Family]

Accession ARO:3000228
DefinitionA category of aminoglycoside O-nucleotidyltransferase enzymes with modification regiospecificity based at the 9-hydroxyl group of the respective antibiotic. These enzymes inactivate aminoglycoside antibiotics, specifically streptomycin, by transfer of an AMP group from an ATP substrate to the 9-hydroxyl group of the compound.
Drug Classaminoglycoside antibiotic
Resistance Mechanismantibiotic inactivation
Classification8 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ aminoglycoside nucleotidyltransferase (ANT)
+ confers_resistance_to_drug_class aminoglycoside antibiotic [Drug Class]
2 ontology terms | Show