rifampin glycosyltransferase [AMR Gene Family]

Accession ARO:3000443
DefinitionThe enzymatic inactivation of rifampin by glycosylation at the 23-OH position.
Drug Classrifamycin antibiotic
Resistance Mechanismantibiotic inactivation
Classification6 ontology terms | Show
Parent Term(s)3 ontology terms | Show
+ rifampin inactivation enzyme
+ participates_in glycosylation of antibiotic conferring resistance
+ confers_resistance_to_drug_class rifamycin antibiotic [Drug Class]
1 ontology terms | Show

Yazawa K, et al. 1993. Antimicrob Agents Chemother 37(6): 1313-1317. Inactivation of rifampin by Nocardia brasiliensis. (PMID 8328779)

Spanogiannopoulos P, et al. 2012. Antimicrob Agents Chemother 56(10): 5061-5069. Characterization of a rifampin-inactivating glycosyltransferase from a screen of environmental actinomycetes. (PMID 22802246)