ribosomal complex

Accession ARO:3000729
DefinitionThe ribosomal complex can be targeted by antibiotics that stabilize the entire complex and prevent further translation. These antibiotics target both subunits in the process of protein translation.
Classification2 ontology terms | Show
Parent Term(s)3 ontology terms | Show
+ protein synthesis machinery targeted by antibiotic
+ targeted_by_antibiotic viomycin [Antibiotic]
+ targeted_by_antibiotic tuberactinomycin [Antibiotic]

Ermolenko DN, et al. 2007. Nat Struct Mol Biol 14(6): 493-497. The antibiotic viomycin traps the ribosome in an intermediate state of translocation. (PMID 17515906)

Modolell J and Vazquez. 1977. Eur J Biochem 81(3): 491-497. The inhibition of ribosomal translocation by viomycin. (PMID 202460)