isoniazid resistant katG [AMR Gene Family]

Accession ARO:3003416
DefinitionBifunctional enzyme with both catalase and broad-spectrum peroxidase activity. It is a catalase-peroxidases that catalyzes the activation of isoniazid. Mutations that arises within this protein cause changes that results in the inability for katG to activate antibiotics, conferring resistance.
Drug Classisoniazid-like antibiotic
Resistance Mechanismantibiotic target alteration
Classification7 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ antibiotic resistant katG
+ confers_resistance_to_drug_class isoniazid-like antibiotic [Drug Class]
1 ontology terms | Show