isoniazid resistant katG [AMR Gene Family]

Accession ARO:3003416
DefinitionBifunctional enzyme with both catalase and broad-spectrum peroxidase activity. It is a catalase-peroxidases that catalyzes the activation of isoniazid. Mutations that arises within this protein cause changes that results in the inability for katG to activate antibiotics, conferring resistance
Drug Classisoniazid
Resistance Mechanismantibiotic target alteration
Classification9 ontology terms | Show
Parent Term(s)3 ontology terms | Show
+ confers_resistance_to_drug_class isoniazid [Drug Class]
+ determinant of isoniazid resistance
+ antibiotic resistant katG
1 ontology terms | Show