frameshift mutation

Ontology CARD's Model Ontology
Accession MO:0000024
DefinitionA frameshift is a sequence change between the translation initiation (start) and termination (stop) codon where, compared to a reference sequence, translation shifts to another reading frame as caused by nucleotide insertions and deletions. In ARO, these are annotated at the protein level with the first changed most N-terminal wildtype amino acid position. Format is given as [wildtype AA][position]fs, e.g. S531fs where S531 is a frameshifted coordinate beginning with codon 531. Termination may also be denoted as: Ter[position]fs.
Classification2 ontology terms | Show
Parent Term(s)3 ontology terms | Show
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