BAL30072 [Antibiotic]

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Accession ARO:3003821
DefinitionBAL30072 is a monocyclic beta-lactam antibiotic belonging to the sulfactams. BAL30072 was found to trigger the spheroplasting and lysis of Escherichia coli rather than the formation of extensive filaments.
Drug Classmonobactam
Classification3 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ monobactam [Drug Class]
2 ontology terms | Show
+ OXA-24 confers_resistance_to_antibiotic
+ OXA-51 confers_resistance_to_antibiotic

Page MG, et al. 2010. Antimicrob. Agents Chemother. 54(6):2291-302 In vitro properties of BAL30072, a novel siderophore sulfactam with activity against multiresistant gram-negative bacilli. (PMID 20308379)

Mushtaq S, et al. 2013. J. Antimicrob. Chemother. 68(7):1601-8 Activity of BAL30072 alone or combined with β-lactamase inhibitors or with meropenem against carbapenem-resistant Enterobacteriaceae and non-fermenters. (PMID 23449829)