Accession ARO:3003822
Synonym(s)octapeptin B5
DefinitionBattacin is a cationic lipopeptide antibiotic produced from a Paenibacillus tianmuensis soil isolate. Battacin kills bacteria in vitro and has potent activity against Gram-negative bacteria, including multidrug-resistant and extremely drug-resistant clinical isolates. The bactericidal kinetics of battacin correlate with the depolarization of the cell membrane, suggesting that battacin kills bacteria by disrupting the cytoplasmic membrane.
Drug Classpeptide antibiotic
Classification3 ontology terms | Show
Parent Term(s)1 ontology terms | Show

Qian CD, et al. 2012. Antimicrob. Agents Chemother. 56(3):1458-65 Battacin (Octapeptin B5), a new cyclic lipopeptide antibiotic from Paenibacillus tianmuensis active against multidrug-resistant Gram-negative bacteria. (PMID 22183171)