peptide antibiotic [Drug Class]

Accession ARO:3000053
DefinitionPeptide antibiotics have a wide range of antibacterial mechanisms, depending on the amino acids that make up the antibiotic, although most act to disrupt the cell membrane in some manner. Subclasses of peptide antibiotics can include additional sidechains of other types, such as lipids in the case of the lipopeptide antibiotics.
Classification1 ontology terms | Show
Parent Term(s)1 ontology terms | Show
Sub-Term(s)
54 ontology terms | Show
+ bacitracin
+ edeine
+ gramicidin
+ tuberactinomycin [Antibiotic]
+ thiostrepton [Antibiotic]
+ defensin [Antibiotic]
+ magainin
+ actinomycin
+ teixobactin [Antibiotic]
+ lipopeptide antibiotic
+ edeine A [Antibiotic]
+ edeine B [Antibiotic]
+ lugdunin [Antibiotic]
+ thusin [Antibiotic]
+ formicin [Antibiotic]
+ lysocin
+ edeine D [Antibiotic]
+ microcin J25 [Antibiotic]
+ edeine F [Antibiotic]
+ BPI [Antibiotic]
+ determinant of resistance to peptide antibiotics confers_resistance_to_drug_class
+ 16s rRNA with mutation conferring resistance to peptide antibiotics [AMR Gene Family] confers_resistance_to_drug_class
+ Bah amidohydrolase [AMR Gene Family] confers_resistance_to_drug_class
+ viomycin phosphotransferase [AMR Gene Family] confers_resistance_to_drug_class
+ lysocin resistant menA [AMR Gene Family] confers_resistance_to_drug_class
+ undecaprenyl pyrophosphate related proteins [AMR Gene Family] confers_resistance_to_drug_class
+ General Bacterial Porin with reduced permeability to peptide antibiotics [AMR Gene Family] confers_resistance_to_drug_class
+ daptomycin resistant gshF [AMR Gene Family] confers_resistance_to_drug_class
+ non-erm 23S ribosomal RNA methyltransferase (A1067) [AMR Gene Family] confers_resistance_to_drug_class
+ lipid A phosphatase [AMR Gene Family] confers_resistance_to_drug_class
+ defensin resistant mprF [AMR Gene Family] confers_resistance_to_drug_class
+ Acinetobacter mutant Lpx gene conferring resistance to colistin [AMR Gene Family] confers_resistance_to_drug_class
+ daptomycin resistant beta-subunit of RNA polymerase (rpoB) [AMR Gene Family] confers_resistance_to_drug_class
+ daptomycin resistant pgsA [AMR Gene Family] confers_resistance_to_drug_class
+ daptomycin resistant cls [AMR Gene Family] confers_resistance_to_drug_class
+ daptomycin resistant walK [AMR Gene Family] confers_resistance_to_drug_class
+ daptomycin resistant gdpD [AMR Gene Family] confers_resistance_to_drug_class
+ daptomycin resistant agrA [AMR Gene Family] confers_resistance_to_drug_class
+ daptomycin resistant drmA [AMR Gene Family] confers_resistance_to_drug_class
+ daptomycin resistant YvlB [AMR Gene Family] confers_resistance_to_drug_class
+ daptomycin resistant CdsA [AMR Gene Family] confers_resistance_to_drug_class
+ daptomycin resistant mprF [AMR Gene Family] confers_resistance_to_drug_class
+ daptomycin resistant liaS [AMR Gene Family] confers_resistance_to_drug_class
+ daptomycin resistant liaR [AMR Gene Family] confers_resistance_to_drug_class
+ daptomycin resistant liaF [AMR Gene Family] confers_resistance_to_drug_class
+ daptomycin-resistant beta prime subunit of RNA polymerase (rpoC) [AMR Gene Family] confers_resistance_to_drug_class
+ daptomycin resistant YybT [AMR Gene Family] confers_resistance_to_drug_class
+ pmr phosphoethanolamine transferase [AMR Gene Family] confers_resistance_to_drug_class
+ MCR phosphoethanolamine transferase [AMR Gene Family] confers_resistance_to_drug_class
+ phoPQ confers_resistance_to_drug_class
+ lipid A acyltransferase [AMR Gene Family] confers_resistance_to_drug_class
+ intrinsic colistin resistant phosphoethanolamine transferase [AMR Gene Family] confers_resistance_to_drug_class
+ major facilitator superfamily (MFS) antibiotic efflux pump [AMR Gene Family] confers_resistance_to_drug_class
+ ATP-binding cassette (ABC) antibiotic efflux pump [AMR Gene Family] confers_resistance_to_drug_class
Publications

Axelsen PH. 2008. Biophys J 94(5): 1549-1550. A chaotic pore model of polypeptide antibiotic action. (PMID 18065456)

Hancock RE, et al. 1999. Antimicrob. Agents Chemother. 43(6):1317-23 Peptide antibiotics. (PMID 10348745)