daptomycin-resistant beta prime subunit of RNA polymerase (rpoC) [AMR Gene Family]

Accession ARO:3003290
DefinitionDaptomycin resistant RNA polymerases include amino acids substitutions which alter the binding affinity of daptomycin to the protein, resulting in antibiotic resistance.
Drug Classpeptide antibiotic
Resistance Mechanismantibiotic target alteration
Classification9 ontology terms | Show
Parent Term(s)5 ontology terms | Show
+ confers_resistance_to_antibiotic daptomycin [Antibiotic]
+ confers_resistance_to_drug_class peptide antibiotic [Drug Class]
+ determinant of resistance to lipopeptide antibiotics
+ antibiotic resistant rpoC
+ derives_from antibiotic sensitive beta-prime subunit of RNA polymerase (rpoC)
1 ontology terms | Show