daptomycin resistant CdsA [AMR Gene Family]

Accession ARO:3004096
DefinitionMutations to the CdsA phosphatidate cytidylyltransferase conferring resistance to daptomycin.
Drug Classpeptide antibiotic
Resistance Mechanismantibiotic target alteration
Classification8 ontology terms | Show
Parent Term(s)3 ontology terms | Show
+ antibiotic resistant gene variant or mutant
+ confers_resistance_to_antibiotic daptomycin [Antibiotic]
+ confers_resistance_to_drug_class peptide antibiotic [Drug Class]
1 ontology terms | Show

Mishra NN, et al. 2017. Antimicrob. Agents Chemother. 61(4): Perturbations of Phosphatidate Cytidylyltransferase (CdsA) Mediate Daptomycin Resistance in Streptococcus mitis/oralis by a Novel Mechanism. (PMID 28115347)