daptomycin resistant liaS [AMR Gene Family]

Accession ARO:3004264
DefinitionMutations in the liaS histidine kinase that confer daptomycin resistance.
Drug Classpeptide antibiotic
Resistance Mechanismantibiotic efflux, antibiotic target alteration
Efflux Regulatorprotein(s) and two-component regulatory system modulating antibiotic efflux
Classification8 ontology terms | Show
Parent Term(s)3 ontology terms | Show
+ part_of daptomycin resistant liaFSR
+ confers_resistance_to_drug_class peptide antibiotic [Drug Class]
+ antibiotic resistant gene variant or mutant
2 ontology terms | Show

Arias CA, et al. 2011. N Engl J Med 365(10): 892-900. Genetic basis for in vivo daptomycin resistance in enterococci. (PMID 21899450)