Accession ARO:3000694
DefinitionMagainins are antimicrobial peptides produced by amphibians skil cells as part of their innate immune system. It is active against a broad range of gram-negative and gram-positive bacteria, fungi and protozoa.
Drug Classpeptide antibiotic
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ peptide antibiotic [Drug Class]
7 ontology terms | Show
+ cell membrane component targeted by antibiotic targeted_by_antibiotic
+ magainin A [Antibiotic]
+ Magainin B [Antibiotic]
+ Magainin G [Antibiotic]
+ Magainin H [Antibiotic]
+ magainin 1 [Antibiotic]
+ magainin 2 [Antibiotic]

Zasloff M, et al. 1988. Proc Natl Acad Sci U S A 85(3): 910-913. Antimicrobial activity of synthetic magainin peptides and several analogues. (PMID 3277183)