Intrinsic peptide antibiotic resistant Lps [AMR Gene Family]

Accession ARO:3005050
DefinitionLpsB is involved in lipopolysaccharide synthesis. It provides intrinsic resistance to colistin and other peptide antibiotics such as polymyxins.
Drug Classpeptide antibiotic
Resistance Mechanismreduced permeability to antibiotic
Classification5 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ confers_resistance_to_drug_class peptide antibiotic [Drug Class]
+ protein modulating permeability to antibiotic
2 ontology terms | Show
+ LpsB
+ LpsA

Hood MI, et al. 2013. Infect. Immun. 81(2):542-51 genetic determinants of intrinsic colistin tolerance in Acinetobacter baumannii. (PMID 23230287)