protein modulating permeability to antibiotic

Accession ARO:3000270
DefinitionEnzymes or other proteins either directly or indirectly reducing overall permeability to antibiotics.
Resistance Mechanismreduced permeability to antibiotic
Classification2 ontology terms | Show
Parent Term(s)2 ontology terms | Show
11 ontology terms | Show
+ marA
+ General Bacterial Porin (GBP)
+ Outer Membrane Porin (Opr) [AMR Gene Family]
+ Sugar Porin (SP) [AMR Gene Family]
+ MipA-interacting Protein [AMR Gene Family]
+ CarO porin [AMR Gene Family]
+ tunicamycin resistance protein [AMR Gene Family]
+ Intrinsic peptide antibiotic resistant Lps [AMR Gene Family]
+ fungal nucleobase transporters [AMR Gene Family]
+ pH-responsive transcription factors [AMR Gene Family]
+ Serine/threonine kinases [AMR Gene Family]

Cohen SP, et al. 1988. J Bacteriol 170(12): 5416-5422. marA locus causes decreased expression of OmpF porin in multiple-antibiotic-resistant (Mar) mutants of Escherichia coli. (PMID 2848006)

Delcour AH. 2009. Biochim Biophys Acta 1794(5): 808-816. Outer membrane permeability and antibiotic resistance. (PMID 19100346)