General Bacterial Porin (GBP)

Accession ARO:3004277
DefinitionGeneral bacterial porins are a family of porins found in the outer membrane of Gram-negative bacteria. They catalyze the energy-independent transport of small molecules across the outer membranes of bacteria. Most of the porins of these family are homotrimeric and have variable selectivity, ranging from being cation-selective, anion-selective or selective for different compounds. The most well characterized members of this family are the OmpF and OmpC porins of Escherichia coli. This family is also known as the classical porins.
Resistance Mechanismreduced permeability to antibiotic
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Publications

Pag├Ęs JM, et al. 2008. Nat. Rev. Microbiol. 6(12):893-903 The porin and the permeating antibiotic: a selective diffusion barrier in Gram-negative bacteria. (PMID 18997824)