CarO porin [AMR Gene Family]

Accession ARO:3004283
DefinitionThe imipenum resistance-associated CarO porin family is composed of the CarO porin originally identified in Acinetobacter baumannii. The loss of these porins is associated with imipenem and meropenem multi-drug resistance. The channels formed by CarO porins show slight cation selectivity.
Drug Classcarbapenem
Resistance Mechanismreduced permeability to antibiotic
Classification6 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ protein modulating permeability to antibiotic
+ confers_resistance_to_drug_class carbapenem [Drug Class]
1 ontology terms | Show
+ carO