Outer Membrane Porin (Opr) [AMR Gene Family]

Accession ARO:3004278
DefinitionThe Opr family consists of porins in Pseudomonas species, and other Gram-negative bacteria, that exhibit a variety of substrate selectivities.
Drug Classmonobactam, carbapenem, cephalosporin, cephamycin, penam, penem
Resistance Mechanismreduced permeability to antibiotic
Classification7 ontology terms | Show
Parent Term(s)8 ontology terms | Show
+ confers_resistance_to_drug_class monobactam [Drug Class]
+ confers_resistance_to_drug_class carbapenem [Drug Class]
+ confers_resistance_to_drug_class cephalosporin [Drug Class]
+ confers_resistance_to_drug_class cephamycin [Drug Class]
+ confers_resistance_to_drug_class penam [Drug Class]
+ determinant of beta-lactam resistance
+ protein modulating permeability to antibiotic
+ confers_resistance_to_drug_class penem [Drug Class]
Sub-Term(s)
2 ontology terms | Show
Publications

Pag├Ęs JM, et al. 2008. Nat. Rev. Microbiol. 6(12):893-903 The porin and the permeating antibiotic: a selective diffusion barrier in Gram-negative bacteria. (PMID 18997824)