co-dependent nonsense SNP

Accession MO:0000025
DefinitionAn AMR detection model parameter to describe concurrent nonsense mutations in multiple genes which produce a resistance phenotype. That is, either mutation independently will not confer resistance but co-mutation in a set of genes does. These mutation parameters are documented in CARD with the notation: [cvterm-id-gene-1],[gene-1-nonsenseSNP]+[cvterm-id-gene-2],[gene-2-nonsenseSNP]+ ... +[cvterm-id-gene-n],[gene-n-nonsenseSNP] e.g. 39879,G247S+40052,D500STOP. This is currently (August 2017) no algorithm for model detection with this parameter.
Classification2 ontology terms | Show
Parent Term(s)2 ontology terms | Show