lugdunin [Antibiotic]

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Ontology CARD's Antibiotic Resistance Ontology
Accession ARO:3003898
DefinitionLugdunin is a thiazolidine-containing cyclic peptide antibiotic isolated from nasal Staphylococcus lugnunensis that prohibits Staphylococcus aureus colony formation. It is a human commensal bacteria, indicating the potential for further antibiotic discoveries from human microbiota.
SMILESCC(C)C[C@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](C(C)C)NC(=O)[C@@H]2CS[C@H](N2)[C@H](C(C)C)NC(=O)[C@@H](C(C)C)NC(=O)[C@H](C(C)C)NC1=O
PubChem121596231
ChEBI133127
ChEMBLCHEMBL5267022
Drug Classpeptide antibiotic
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ peptide antibiotic [Drug Class]
Publications

Zipperer A, et al. 2016. Nature 535(7613):511-6 Human commensals producing a novel antibiotic impair pathogen colonization. (PMID 27466123)

Curator Acknowledgements
Curator Description Most Recent Edit