oleic acid [Antibiotic]

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Accession ARO:3003958
Synonym(s)Cis-9-Octadecenoic acid Cis-Oleic acid Elaidoic acid Oleate
DefinitionOleic acid is a fatty acid that occurs naturally in various animal and vegetable fats and oils. Oleic acid is found to have antibacterial activity, particularly in inhibiting the growth of several Gram-positive bacterial species.
Drug Classantibacterial free fatty acids
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
1 ontology terms | Show
+ farAB confers_resistance_to_antibiotic

Dilika F, et al. 2000. Fitoterapia 71(4):450-2 Antibacterial activity of linoleic and oleic acids isolated from Helichrysum pedunculatum: a plant used during circumcision rites. (PMID 10925024)

Stenz L, et al. 2008. FEMS Microbiol. Lett. 287(2):149-55 Impact of oleic acid (cis-9-octadecenoic acid) on bacterial viability and biofilm production in Staphylococcus aureus. (PMID 18754790)

Speert DP, et al. 1979. Infect. Immun. 26(3):1202-10 Bactericidal effect of oleic acid on group A streptococci: mechanism of action. (PMID 393631)

Desbois AP, et al. 2010. Appl. Microbiol. Biotechnol. 85(6):1629-42 Antibacterial free fatty acids: activities, mechanisms of action and biotechnological potential. (PMID 19956944)

Lee EH, et al. 1999. Mol. Microbiol. 33(4):839-45 The farAB-encoded efflux pump mediates resistance of gonococci to long-chained antibacterial fatty acids. (PMID 10447892)