prothionamide [Drug Class]

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Accession ARO:3004025
Synonym(s)protionamide
DefinitionProthionamide is a thioamide derivative with antibacterial properties. It increases cell wall permeability and decreases cell wall damage resistance by inhibition of mycolic acid synthesis, resulting in cell death. It is particularly used to treat M. tuberculosis and M. leprae infections.
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
Publications

Matsuo Y, et al. 1981. Int. J. Lepr. Other Mycobact. Dis. 49(3):302-6 Prothionamide and prothionamide-S-oxide in experimental leprosy. (PMID 6459296)