lethal factor

Accession VIRO:0000089
DefinitionLF is a zinc-dependent protease that cleaves mitogen-activated protein kinase kinases (MAPKKs) in their amino-terminal regions. It induces the cytokine-independent shock-like death associated with anthrax.
Classification8 ontology terms | Show
Parent Term(s)2 ontology terms | Show

Okinaka RT, et al. 1999. J. Bacteriol. 181(20):6509-15 Sequence and organization of pXO1, the large Bacillus anthracis plasmid harboring the anthrax toxin genes. (PMID 10515943)

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