Ethambutol resistant iniB [AMR Gene Family]

Accession ARO:3004136
DefinitionPoint mutations occurring in the iniB region of the iniBAC operon shown to confer resistance to ethambutol
Drug Classpolyamine antibiotic
Resistance Mechanismantibiotic efflux, antibiotic target alteration
Efflux Componentefflux pump complex or subunit conferring antibiotic resistance
Classification11 ontology terms | Show
Parent Term(s)4 ontology terms | Show
+ confers_resistance_to_antibiotic ethambutol [Antibiotic]
+ confers_resistance_to_drug_class polyamine antibiotic [Drug Class]
+ determinant of resistance to polyamine antibiotics
+ Antibiotic resistant iniB
Sub-Term(s)
1 ontology terms | Show
Publications

Ramaswamy SV, et al. 2000. Antimicrob Agents Chemother 44(2): 326-336. Molecular genetic analysis of nucleotide polymorphisms associated with ethambutol resistance in human isolates of Mycobacterium tuberculosis. (PMID 10639358)