antibiotic resistance fabG [AMR Gene Family]

Accession ARO:3004284
DefinitionfabG is a 3-oxoacyl-acyl carrier protein reductase involved in lipid metabolism and fatty acid biosynthesis. The bacterial biocide Triclosan blocks the final reduction step in fatty acid elongation, inhibiting biosynthesis. Point mutations in fabG can confer resistance to Triclosan.
Drug Classtriclosan
Resistance Mechanismantibiotic target alteration
Classification7 ontology terms | Show
Parent Term(s)3 ontology terms | Show
+ antibiotic resistant gene variant or mutant
+ confers_resistance_to_drug_class triclosan [Drug Class]
+ derives_from antibiotic sensitive fabG
1 ontology terms | Show