pore-forming toxin

Accession VIRO:0000184
DefinitionClass of bacterial toxins which act to bind to a target cell and increase its permeability for other molecules. Resultant permeability is typically selective, but the nature of that selectivity is toxin-specific
Classification5 ontology terms | Show
Parent Term(s)1 ontology terms | Show
2 ontology terms | Show
+ alpha pore-forming toxin [Virulence Factor]
+ beta pore-forming toxin [Virulence Mechanism]

Dal Peraro M, et al. 2016. Nat. Rev. Microbiol. 14(2):77-92 Pore-forming toxins: ancient, but never really out of fashion. (PMID 26639780)