alpha pore-forming toxin [Virulence Factor]

Accession VIRO:0000185
Synonym(s)alpha PFT
DefinitionA subclass of pore-forming toxins for which the secondary structure consists of alpha-helices. The general mechanism involves the membrane attachment of monomers from which alpha-helices are then extracted and inserted into the membrane.
Classification10 ontology terms | Show
Parent Term(s)2 ontology terms | Show
3 ontology terms | Show

Dal Peraro M, et al. 2016. Nat. Rev. Microbiol. 14(2):77-92 Pore-forming toxins: ancient, but never really out of fashion. (PMID 26639780)